Drug Classification Mode of Action Indications Contraindications Side effects Nursing responsibilities
Generic Rabies Used in a post Pre- & If you are feverish Signs of an allergic Wounds must be
name: Immune exposure post- or if you have an reaction, like rash; immediately
Globulin prophylaxis exposur acute disease (in hives; itching; red, washed/flushed for 15
Verorab (Vaccine) regimen that this case, it is swollen, blistered, or minutes and
e
Brand includes active immuniz preferable to peeling skin with or disinfected.
name: immunization ation postpone without fever;
with rabies vaccination).Post- wheezing; tightness Rabies PEP should
against
RabAvert vaccine and exposure in the chest or be instituted
rabies.
passive vaccination: Given throat; trouble immediately. PEP
immunization the fatal outcome breathing, consists of a course of
with RIG. of the declared swallowing, or potent, effective
rabies infection, talking; unusual rabies vaccine that
Dosage: RIG provides there are hoarseness; or meets WHO
immediate, no contraindicati swelling of the recommendations and
The temporary administration of
ons to post- mouth, face, lips,
vaccinatio rabies virus- rabies
exposure tongue, or throat.
n neutralizing immunoglobulin
vaccination.
schedule antibodies until Signs of meningitis
should be the patient has like headache with PEP must be applied
adapted an fever, stiff neck, using vaccine
according immunologic upset stomach, regimens and
to the response to confusion, or if lights administration routes
circumsta active bother the eyes. that have been proven
nces of immunization Feeling very tired or to be safe and
the with rabies weak. Not able to effective.
vaccinatio
n and the vaccine and move face muscles PEP does not have
subject's produces virus- as much. Muscle contraindications if
rabies neutralizing weakness. purified rabies
immune antibodies immunoglobulin and
status. Not able to move. vaccine are used.
Given IM Very bad headache. Pregnancy and
Feeling confused. infancy are not
contraindications to
Change in eyesight. PEP
Swollen gland. Patients presenting
for rabies PEP even
Very bad dizziness
months after having
or passing out.
been bitten should be
A burning, treated as if the
numbness, or contact had recently
tingling feeling that occurred.
is not normal.
PEP should be
Trouble controlling administered even if
body movements. the suspect animal is
not available for
Irritation where the testing or observation.
shot is given. However, vaccine and
immunoglobulin
Flu-like signs. administration may be
These include
discontinued if the
headache,
weakness, fever, animal involved: is a
vaccinated dog (cat or
shakes, aches, ferret) that following
pains, and sweating. observation for 10
days, remains healthy
Upset stomach.
or is humanely killed
Muscle or joint pain. and declared negative
for rabies by a WHO
Dizziness. prescribed laboratory
test.
In areas enzootic for
(canine and wildlife)
rabies, PEP should be
instituted immediately
unless adequate
laboratory
surveillance and data
indicates that the
species involved is
not a vector of rabies