Emergências Psiquiátricas
Emergências Psiquiátricas
Emergências Psiquiátricas
KEYWORDS
Suicide Homicide Mania Psychosis Agitation Psychiatric emergency
KEY POINTS
Psychiatric emergencies, such as mania, psychosis, and suicidal or homicidal ideation,
present as an acute disturbance of thought, behavior, or mood that require prompt inter-
vention to prevent imminent danger.
The first priority in a psychiatric emergency is ensuring the safety of the patient and those
surrounding.
Initial assessment should consist of a thorough history and physical examination, to rule
out underlying medical causes, while simultaneously establishing a safe environment for
patient and clinician.
It is imperative to debrief with the patient, family, and the health care team following the
treatment of a psychiatric emergency.
There are important legal considerations, particularly concerning involuntary admission,
surrounding psychiatric emergencies.
INTRODUCTION
Northwestern McGaw Family Medicine Residency Program, Erie Family Heath Center, 2750 West
North Avenue, Chicago, IL 60647, USA
* Corresponding author.
E-mail address: swheat@eriefamilyhealth.org
The most important first step in the management of a psychiatric emergency is the
initial evaluation. An evaluation should take place in a quiet, private room where the
safety of the patient, provider, staff, and other individuals can be maintained. When-
ever there is a patient who is extremely agitated, aggressive, or suicidal, the health
care team needs to be aware and alert. Patients who need a crisis intervention in a
psychiatric emergency typically fall into three main categories: (1) acute psychosis
and mania, (2) suicidal and depressed patients, and (3) aggressive and homicidal pa-
tients. For each type of psychiatric crisis, the screening and management process
may differ and require specific types of interventions.
Table 1
Differential diagnosis for patients with mania or acute psychosis
Data from Sood TR, McStay CM. Evaluation of the psychiatric patient. Emerg Med Clin North Am
2009;27(4):669–83, ix; and Hirschfeld RM, Russell JM. Assessment and treatment of suicidal
patients. N Engl J Med 1997;337(13):910–5.
After obtaining the history, the clinician should determine how alert and oriented the
patient is to person, place, and situation. The clinician can then assess for dissociation
from reality. This may include assessing for hallucinations and delusions, listening for
disorganized thinking or behavior, tangential speech, and observing for blunted affect
and avolition. This includes assessing activities of daily living, such as hygiene or
eating, and instrumental activities of daily living, such as shopping or managing
money. Next, the clinician should obtain the past medical history including psychiatric
history and history of substance use. The physical examination should include vital
signs, general appearance, attention, and interaction. A full neurologic examination
including assessment of alertness, orientation, strength, sensation, cranial nerves,
gait, cerebellar tests, and reflexes should be done. Finally, specific organ systems
should be assessed particularly looking for signs of infection, hepatic dysfunction,
trauma, and cardiac disease.1 Provisional diagnoses of the mental disorder and any
potentially contributing medical diagnoses or substance use should be made to guide
further evaluation and management decisions (Fig. 1).4
Screening tools can be useful for assessment of the patient with acute psychosis or
mania. The Mini Mental Status Exam and the Quick Confusion Scale are useful tools to
help providers evaluate a patient’s cognitive functioning.12 In addition, a patient’s level
of agitation is assessed using the Agitation Behavior Scale or the Behavioral Activity
Box 1
Patients likely to have coexisting medical illness
1. Elderly
2. History of substance abuse
3. No history of psychiatric history
4. Pre-existing medical illness
5. Lower socioeconomic status
Data from Sood TR, McStay CM. Evaluation of the psychiatric patient. Emerg Med Clin North
Am 2009;27(4):669–83, ix.
344 Wheat et al
Box 2
Key points of assessment of suicidal patient
History
Current circumstances
Mental state
Suicidal thinking
Suicidal behaviors
Data from Practice guideline for the assessment and treatment of patients with suicidal behav-
iors. Am J Psychiatry 2003;160(11 Suppl):1–60.
Ratings Scale.1,13 Failure to refer to standardized criteria for assessing the level of risk
is a common pitfall and can lead to inadequately triaging the patient.14
After a history and examination have been completed, the clinician may consider
laboratory studies. If a patient has a significant psychiatric history, laboratory studies
are unlikely to add much useful information. However, certain tests can be done to rule
out common medical causes and substance use. The diagnostic evaluation should be
dictated by the specific psychiatric symptoms and the patient’s history and physical
examination.15 For example, a urine drug screen or blood alcohol level may be useful
in assessing for intoxication and specific substance abuse. A lumbar puncture is only
useful in the setting of suspected meningitis or encephalitis. Computed tomography
scan or other imaging is unlikely to add much information if there are no focal findings
on examination, except in the case of an elderly patient.1,16
Suicidal and Homicidal Ideation
The evaluation of a patient with suicidal ideation is different than that of a patient with
acute psychosis or mania. This evaluation is done to identify factors that increase or
decrease risk of suicide, to address immediate safety to determine the most appro-
priate setting for treatment, and to develop a differential diagnosis that can further
guide the plan of treatment. Throughout this evaluation, it is important for the clinician
to elicit details surrounding the patient’s history and situation, and to maintain a good
rapport with the patient while demonstrating empathy.4
Similar to the assessment of patients with other psychiatric emergencies, the
clinician should identify specific psychiatric signs and symptoms and assess for
immediate safety (Box 3). During questioning of the patient, the clinician should inquire
about past suicidal behavior and frequency of attempts and means. The clinician
should also assess for the consumption of drugs and alcohol, because these may
make the patient more impulsive, aggressive, and cognitively impaired. There should
be an assessment of what treatments the patient has had previously and their
response to interventions. An assessment of family history of mental illness and partic-
ularly of suicides of family members is important in determining risk. The clinician
should determine the current social situation and any recent losses of relationships,
status, or employment. The patient should also be evaluated for positive coping skills,
Fig. 1. Evaluation of patient with psychiatric emergency. (Data from Sood TR, McStay CM.
Evaluation of the psychiatric patient. Emerg Med Clin North Am 2009;27(4):669–83, ix.)
Psychiatric Emergencies 345
Box 3
Risk factors for eventual suicide
Male sex
Age greater than 60
Widowed or divorced
White or Native American
Lives alone
Unemployed/financial problems
Recent adverse event
Depression
Schizophrenia
Substance abuse
History of suicide attempts or ideation
Feelings of hopelessness
Panic attacks
Severe anxiety
Severe anhedonia
Data from Sood TR, McStay CM. Evaluation of the psychiatric patient. Emerg Med Clin North
Am 2009;27(4):669–83, ix; and Hirschfeld RM, Russell JM. Assessment and treatment of suicidal
patients. N Engl J Med 1997;337(13):910–5.
MANAGEMENT GOALS
Once the evaluation has been completed, the clinician must determine whether the
patient is willing to form an alliance that allows for successful assessment and treat-
ment. The clinician should determine if the patient is at risk of harm to self or others
and then if involuntary treatment and admissions are necessary. The clinician should
then develop a specific plan, which includes immediate treatment, disposition, and
follow-up.4
Acute Psychosis, Mania, and Agitated or Homicidal Patients
The first priorities regardless of the cause of behavior are stabilizing and ensuring the
safety of the patient, staff, and family or friends. After ensuring the safety of the patient
and staff, the initial approach to an acutely agitated patient should involve assisting the
patient to manage his or her stress. The methods of assisting the patient are via behav-
ioral interventions, pharmacologic interventions, or both if necessary.2,17,18 When the
patient has a comorbid medical illness contributing to the psychiatric emergency, it is
crucial for the clinician to also treat the medical illness. In some cases, the medical
illness is the cause of the psychiatric emergency and is therefore important for the
clinician to distinguish. The clinician must distinguish whether these emergencies
are secondary to substance or medication use or organic disease using certain clinical
criteria, including (1) greater than 30 years with no personal history of psychiatric
illness, (2) history of illness or substance use, (3) sudden onset or fluctuation of psychi-
atric symptoms, (4) confusion and disorientation to time and place, (5) symptoms not
corresponding to a specific psychiatric diagnosis, (6) abnormal vital signs, (7) coexist-
ing signs of specific organic illness, and (8) poor response to treatment.11 The pres-
ence of these clinical criteria alters the goals of care. Additionally, the provider must
determine the most appropriate location of care. The locations chosen must allow
the patient to be treated and have the least amount of restrictiveness while still main-
taining safety (Box 4).
Suicidal Ideation
Treatment of the patient with suicidal ideation should focus on mitigating risk and
strengthening protective factors that are modifiable (Box 5). Such modifiable factors
include patient safety, associated psychological or social stressors, social support
networks, and potentially treatable psychiatric disorders. When managing a patient
with suicidal ideation, the clinician must first foster a therapeutic alliance while
attending to patient safety. With use of the information gathered in the assessment,
a treatment setting should be determined and a treatment plan developed. The
clinician should promote adherence to the treatment plan with the patient and any per-
sons providing social support through education and should coordinate care and
Box 4
Criteria for psychiatric admission
Adapted from Zun LS. Evidence-based evaluation of psychiatric patients. J Emerg Med
2005;28(1):35–9.
Psychiatric Emergencies 347
Box 5
Suicide treatment plan based on risk
Data from Practice guideline for the assessment and treatment of patients with suicidal behav-
iors. Am J Psychiatry 2003;160(11 Suppl):1–60.
collaborate with other clinicians as necessary. After establishing and beginning the
treatment plan, the patient should be continuously monitored for psychiatric status
and treatment response while also reassessing safety and suicide risk.4,19
NONPHARMACOLOGIC STRATEGIES
Acute Psychosis, Mania, and Agitated or Homicidal
When approaching a patient with acute agitation, behavioral strategies should be first
line. Behavioral strategies focus on using verbal de-escalation, such as described by
Richmond and colleagues,17 to help the patient to calm and self-regulate his or her
emotional state, and then allow the patient to begin to engage in his or her own treat-
ment plan. The general approach consists of first helping the patient to feel safe by
creating a nonthreatening environment, and speaking in calm, low tones. The inter-
viewer attempting to engage with the patient should also be aware of the need for
additional back up staff, should safety become a concern.2,17 Working from an estab-
lished rapport, the interviewer should then begin the discussion as to how to proceed
with treatment. The interview should be concise, clear, and to the point. The inter-
viewer should listen carefully to the patient and attempt to reach an understanding
if possible. When discussing next treatments, it is helpful to lay out the range of
options available and, if possible, allow the patient to choose. For instance, the inter-
viewer may discuss that she would like to give the patient a medication to help him
keep calm. The interviewer may then offer options, that is, would the patient rather
try a pill or an injection. When the plan has been decided on, the provider should
then review with the patient to gauge his or her understanding and engagement as
an active participant in their own care.17
Suicidal Ideation
The first aspect of management of a patient with suicidal ideation is to find a safe place
as the treatment location.1 The decision of where to treat a suicidal patient depends on
348 Wheat et al
PHARMACOLOGIC STRATEGIES
Acute Psychosis, Mania, and Agitation or Homicidal Ideation
Should medications become necessary in the management of an acutely psychotic or
agitated patient, there are numerous approaches, both general and specific. First-line
approach for an agitated, but cooperative patient should consist of oral medications
when possible. If rapid intervention or sedation is required, parenteral medications
should be used.15,16 A general approach to medications by suspected diagnosis, as
proposed by consensus guidelines, is outlined in Table 2 and Box 6.
In some cases when the agitated patient suffers from underlying medical comorbid-
ities, it is important to adjust medications used and avoid others to prevent further
complications. Benzodiazepines should be avoided in patients with chronic obstruc-
tive pulmonary disease, the elderly, and patients with known drug-seeking behavior or
history of dependence and/or abuse. For patients with history of neurologic side
effects, including akathisia, tardive dyskinesia, neuroleptic malignant syndrome, dys-
tonia, or parkinsonian symptoms, typical antipsychotic medications should not be
used (Table 3).10
Suicidal Ideation
The pharmacologic treatment of the patient with suicidal ideation depends on the
psychiatric diagnosis. In general, evidence for the use of antidepressants is inconclu-
sive for patients with suicidal ideation. Their proven benefits among patients with
depressive episodes and anxiety are, however, in support of their use with suicidal pa-
tients. When using an antidepressant, it is preferable to use one with little risk of
Psychiatric Emergencies 349
Table 2
Pharmacologic treatments in psychiatric emergency
lethality by means of an acute overdose. For this reason selective serotonin reuptake
inhibitors or newer agents are preferable. For patients with insomnia, agitation, panic
attacks, or psychic anxiety, benzodiazepines can be used on a short-term basis; how-
ever, when used, long-acting benzodiazepines are preferable and should be tapered.
If benzodiazepines are not desired, other calming medications, such as trazadone, low
doses of second-generation antipsychotics, and anticonvulsants can be used. There
is evidence suggesting a benefit to the use of longer-term maintenance with lithium
salts in reducing suicide and suicide attempts among patients with bipolar disorder
and some evidence for use in major depressive disorder. Among patients with
schizoaffective disorder, clozapine has demonstrated decreased suicide risk. How-
ever, with the risk of agranulocytosis and myocarditis, this medication should be
reserved for those with frequent suicidal ideation or suicide attempts. Second-
generation antipsychotics, such as risperidone, olanzapine, and quetiapine, are pref-
erable to the first-generation antipsychotics.
350 Wheat et al
Box 6
Medications for agitation and psychosis
Benzodiazepines
Diazepam, 5–10 mg po q 30–60 minutes (average dose, 20–60 mg)
Lorazepam, 1–3 mg po or IM q 30–60 minutes
Typical Antipsychotics
Haloperidol, 5–10 mg po or 5 mg IM every 30–60 minutes (average dose, 10–20 mg)
Atypical Antipsychotics
Olanzapine, 5–10 mg po or 10 mg IM
Ziprasidone, 20–40 mg po bid or 10 mg IM q 2 hours or 20 mg IM q 4 hours
Risperidone, 2 mg po daily, increase by 1–2 mg q 24 hours until goal 4–8 mg; 25 mg IM q
2 weeks, start with po and continue oral for 3 weeks
Quetiapine, 25–50 mg po bid, increase by 25–50 mg bid until goal of 300–400 mg daily
Adapted from Allen MH, Currier GW, Hughes DH, et al. The expert consensus guideline series.
Treatment of behavioral emergencies. Postgrad Med 2001;(Spec No):1–88; [quiz 89–90]; with
permission.
After any involuntary intervention with an agitated patient, it is the responsibility of the
clinician who ordered such interventions to try to restore the therapeutic relationship
and lessen the impact of any trauma from restraining interventions and prevent the risk
Table 3
Preferred medications for comorbid medical conditions
Preferred Alternate
Medical Condition Medication Medication Avoid
Chronic obstructive pulmonary disease TA AA BNZ
Cardiac (arrhythmia or abnormal conduction) BNZ TA ––
AA
Delirium TA AA ––
Dementia AA –– ––
TA
Elderly AA TA BNZ
History of akathisia BNZ –– TA
AA
History of tardive dyskinesia, neuroleptic malignant BNZ AA TA
syndrome, dystonia, parkinsonian symptoms
Mental retardation/developmental delay AA –– ––
History for drug seeking, abuse, or dependence –– AA BNZ
TA
History of seizures BNZ AA ––
Elevated blood alcohol and symptoms of withdraw BNZ –– ––
LEGAL CONSIDERATIONS
There are special legal considerations concerning patients with psychiatric emergen-
cies. The 1975 US Supreme Court ruling in the case of O’Conner v Donaldson gave
persons with mental illness rights when it came to involuntary admission. This ruling
indicated that mental illness alone was not sufficient for an involuntary admission.1,11
Following this ruling, states also restricted the involuntary admission to a predeter-
mined time period of days to weeks after which time the patient was entitled to a court
hearing to determine if the involuntary admission should continue. This time is
commonly 72 hours and often known as the 72-hour hold (Box 7).1,11
In response to these criteria, the American Psychiatric Association developed a
model in which a patient must meet all six criteria to be eligible for involuntary
admission: (1) mental illness, (2) danger to self or others, (3) refusal to consent,
352 Wheat et al
Box 7
Criteria for involuntary admissions
1. Mental illness
2. Danger to self or others
3. Refusal to consent
4. Treatability
5. Lack capacity to make treatment decisions
6. Hospitalization is least restrictive treatment
From Sood TR, McStay CM. Evaluation of the psychiatric patient. Emerg Med Clin North Am
2009;27(4):669–83, ix; with permission.
(4) treatability, (5) lack the capacity to make treatment decisions, and (6) hospitaliza-
tion as the least restrictive treatment.1 To commit a patient, the physician has to com-
plete an initial certificate and hold the patient in a psychiatric facility until further legal
proceedings. When completing a petition for involuntary admission, the clinician
should make three copies for (1) medical record, (2) ambulance/police, and (3) hospital
records. Then the physician has 72 hours to hold a hearing for involuntary hospitaliza-
tion or the patient is allowed to leave. Involuntary commitment statutes vary from state
to state, thus it is important for clinicians to be aware of the statutes and processes in
their jurisdiction.1
For patients with homicidal ideation, clinicians should be aware of civil commitment
laws in their jurisdiction. In some jurisdictions, physicians are legally responsible for
informing the potential victim and/or the police.1
SUMMARY/DISCUSSION
care medical providers, including nursing and support staff, need to be trained in the
assessment, treatment, and management of these patients.
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