DRUG STUDY

Name of Drug Classification Mechanism of Action Indication Contraindications Side Effects Nursing Responsibilities
of Drug
DRUG STUDY
Generic Name: Therapeutic: Bind to bacterial cell Treatment of Hypersensitivity to GI: Before:
Cefuroxime Anti-infectives wall membrane, It is effective for cephalosporins Diarrhea,
 Determine history
causing cell death the treatment of and related nausea, antibiotic-
Trade Name: Pharmacologic: penicillinase- antibiotics; associated colitis. of hypersensitivity reacti
Ceftin Second Therapeutic Effects: producingNeisseria pregnancy
ons to cephalosporins,
generation Bactericidal action (category B), Skin:
gonorrhoea(PPNG).
Cephalosporins lactation. Ra sh , penicillins, and history
Effectively treats
pruritus, urticaria.
Pregnancy bone and joint of allergies, particularly
Catergory B infections, Urogenital: to drugs, before therapy
bronchitis, Increased serum
meningitis, creatinine and is initiated.
gonorrhea, otitis BUN, decreased  Lab tests: Perform
media, creatinine
clearance. culture and sensitivity
pharyngitis/tonsilliti
s, sinusitis, lower tests before initiation of
respiratory tract Hemat:
Hemolytic anemia therapy and periodically
infections, skin and
soft tissue during therapy if
MISC:
infections, urinary Anaphylaxis indicated. Therapy may
tract infections, and
be instituted pending
is used for surgical
prophylaxis, test results. Monitor
reducing or periodically BUN and
eliminating
infection. creatinine clearance.

During:
DRUG STUDY

 Inspect IM and IV
injection sites frequently
for signs of phlebitis.
 Monitor for
manifestations
of hypersensitivity (see
Appendix F).
Discontinue drug and
report their appearance
promptly.
 Monitor I&O rates
and pattern: Especially
important in severely ill
patients receiving high
doses. Report any
significant changes.
 Report onset of loose
stools or diarrhea.
Although
pseudomembranous
colitis (see Signs &
Symptoms, Appendix F)
DRUG STUDY

rarely occurs, this

potentially life-
threatening
complication should be
ruled out as the cause
of diarrhea during and
after antibiotic therapy.
After:
 Instruct patient to take
medication around the
clock at evenly spaced
times and to finish the
medication completely,
even if feeling better
 Advise patient to report
signs of superinfection
and allergy
 Instruct patient to notify
health professional if
fever and diarrhea
develop