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Coag 6

The document discusses the coagulation process, which involves three pathways - the intrinsic pathway, extrinsic pathway, and common pathway. The intrinsic pathway is activated by platelet factor 3 in the presence of calcium and involves coagulation factors VIII and IX. The extrinsic pathway is activated by tissue factor in the presence of calcium and factor VII. Both pathways activate factor X and lead to the common pathway, which involves the conversion of prothrombin to thrombin and thrombin converting fibrinogen to fibrin to form a blood clot.

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92 views1 page

Coag 6

The document discusses the coagulation process, which involves three pathways - the intrinsic pathway, extrinsic pathway, and common pathway. The intrinsic pathway is activated by platelet factor 3 in the presence of calcium and involves coagulation factors VIII and IX. The extrinsic pathway is activated by tissue factor in the presence of calcium and factor VII. Both pathways activate factor X and lead to the common pathway, which involves the conversion of prothrombin to thrombin and thrombin converting fibrinogen to fibrin to form a blood clot.

Uploaded by

pieterinpretoria391
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Coagulation

Study online at quizlet.com/_3182z


a

1. activated proenzymes (usually factor XII): platelet factor (PF-3)


2. Ca2: clotting factor (VII)
3. Ca2+: clotting factors (VIII,IX)
4. clotting factors (VIII, IX): factor X activator complex
5. clotting factor (VII): tissue factor complex
6. coagulation phase diagram:

7. common pathway: Factor X, Prothrombinase, prothrombin, thrombin, fibrin, fibrinogen.


8. extrinsic pathway: tissue damage, tissue factor (factor III), Ca2, clotting factor (VII), tissue factor complex.
9. Factor X: prothrombinase
10. fibrinogen: fibrin
11. intrinsic pathway: activated proenzymes (usually factor XII) platelet factor (PF-3), Ca2, clotting factors (VIII, IX), factor X activator
complex.
12. platelet factor (PF-3): Ca2
13. prothrombin: thrombin
14. prothrombinase: prothrombin
15. thrombin: fibrinogen
16. Tissue damage: tissue factor (factor III)
17. tissue factor (factor III): Ca2

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