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Proses Lipogenesis

This document summarizes the process of lipogenesis. It involves glucose entering the cell and being converted to pyruvate then acetyl-CoA which can then be used to synthesize fatty acids through a series of reactions. The fatty acids are converted to acyl-CoA which react with glycerol to form triglycerides. Lipolysis is the breakdown of triglycerides into glycerol and free fatty acids through the action of hormone-sensitive lipase when stimulated by compounds like epinephrine that increase cyclic AMP levels.

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914 views2 pages

Proses Lipogenesis

This document summarizes the process of lipogenesis. It involves glucose entering the cell and being converted to pyruvate then acetyl-CoA which can then be used to synthesize fatty acids through a series of reactions. The fatty acids are converted to acyl-CoA which react with glycerol to form triglycerides. Lipolysis is the breakdown of triglycerides into glycerol and free fatty acids through the action of hormone-sensitive lipase when stimulated by compounds like epinephrine that increase cyclic AMP levels.

Uploaded by

Ary Rio Pambudi
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Proses lipogenesis

Glikolisis

Beta-oksidasi
FFA

Glukosa
Insulin
mentransp
ort

Masuk dalam sel

Asil koa by asil


koa sintase

Glukosa 6 fosfat
Masuk dalam
mitokondria
diubah dulu jadi
acyl-karnitin

Dalam proses
Dihidrosi
aseton

piruvat

Karnitin
mentranspo
rt

Di ubah jdi Asil

Di ubah jdi Asitel


Di reduksi jadi gliserol

Di ubah jdi Acyl coa


dalam proses
lipogenesis
Gliserol + acy-coa
diesterifikasi ->
Trigliserida

lipolisis
Oleh enzim hormon
sensitif lipase dipecah
butuh cAMP

Penginhibisi enzim
:

hamba

ATP

Pengaktifi enzim :
1.ACTH
2.TSH
3.glucagon
4.katekolamin

Diubah
jd
cAMP

Adenyl cyclase

aktifasi

ATP ->cAMP
Di ubah
jd

aktifasi
Phospho diesterae
cAMP->5AMP
Sintesis VLDL

Adenyl cyclase

5AMP

ATP ->cAMP
FFA

gliserol
darah

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