BLOOD
ERYTHROCYTES
(HEMATOCRIT)
45%
BUFFY COAT
<1%
PLATELETS
PLASMA (MATRIX)
55%
LEUKOCYTES
(WBCs)
GRANULOCYTES
(polymophonuclear
- PMN)
NEUTROPHILS
40-75%
Extravascular
Extravascular
phagocytosis
Barr Bodies
1 (lysosomes)
2 (enzymes, activators)
3
3 (phosphatases,
(phosphatases,
metalloproteinases)
EOSINOPHILS
2-4%
Bi-lobed, peripheral
nucleus
Phagocytosis
Parasites, chronic infection,
allergic rxn
Specific (crystalloid bodies)
Non-specific (lysosomes)
FIBRINOGEN +
CLOTTING FACTORS
SERUM
AGRANULOCYTES
BASOPHILS
0.5-1%
S-shaped, bi-lobed
nucleus
Specific (Heparin,
Histamine, Hep Sulfate)
Non-Specific
(Lysosomes)
LYMPHOCYTES
20-35%
Round, dark nucleus
B- and T-lymphocytes, NK cells
MONOCYTES
3-8%
Crescent/kidney-shaped
Crescent/kidney-shaped
nucleus
Small lysosome granules
Phagocytosis
(become
Phagocytosis (become
macrophages in the blood))