PFT Interpretation Algorithm
FEV1
RV
Normal
Obstructive
(Decreased FEV1/FVC <70%)
Mild
Moderate
Severe
>75
75-60
60-40
<40
80-120
120-150
150-175
Reversible if FEV1 or FVC increase by more than 15% with Bronchodilator Inhalation
Irreversible if No Chnage with Bronchodialtor Inhalation
>200
Normal
Restrictive
(Decreased TLC or FVC <80%)
Mild
Moderate
Severe
TLC or FVC
>80
80-60
60-50
<50
FEV1
>75
>75
>75
>75
RV
120-80
120-80
80-70
70
It's Parenchymal in origin if DLCO is decreased-like Interstitial Lung diseases
It's Extraparenchymal in origin if DLCO is normal -Think of Neuromusclular disorders/Skeletal as Kyphoscoliosis/Obesity/Pleural
effusion and Heavy Ascites
Pulmonary Embolism/Pulmonary Hypertension
Normal PFTs+Decreased DLCO
Pulmonary Function Values
Forced vital capacity (FVC). This measures the amount of air you can exhale with force after you inhale as deeply as possible.
Forced expiratory volume (FEV1). This measures the amount of air you can exhale with force in one breath. The amount of air you exhale
may be measured at 1 second (FEV1), 2 seconds (FEV2), or 3 seconds (FEV3). FEV1 divided by FVC can also be determined.
Forced expiratory flow 25% to 75%. This measures the air flow halfway through an exhale.
Peak expiratory flow (PEF). This measures how quickly you can exhale. It is usually measured at the same time as your forced vital capacity
(FVC).
Total lung capacity (TLC). This measures the amount of air in your lungs after you inhale as deeply as possible.
Functional residual capacity (FRC). This measures the amount of air in your lungs at the end of a normal exhaled breath.
Residual volume (RV). This measures the amount of air in your lungs after you have exhaled completely. It can be done by breathing in helium
or nitrogen gas and seeing how much is exhaled.
Expiratory reserve volume (ERV). This measures the difference between the amount of air in your lungs after a normal exhale
(FRC) and the amount after you exhale with force (RV).
Pulmonary Function Values(Obstructive vs Restrictive)
Lung function test
Restrictive
Obstructive
Forced vital capacity (FVC)
Lower than predicted value
Normal or lower than predicted value
Forced expiratory volume (FEV1)
Normal or lower
Lower
FEV1/FVC
Normal or higher
Lower
Forced expiratory flow 25% to 75%
Normal or lower
Lower
Peak expiratory flow (PEF)
Normal or lower
Lower
Maximum voluntary ventilation (MVV)
Normal or lower
Lower
Total lung capacity (TLC) (VT)
Lower
Normal or higher
Functional residual capacity (FRC)
Normal or lower
Higher
Residual volume (RV)
Normal, lower, or higher
Higher
Expiratory reserve volume (ERV)
Normal or lower
Normal or lower
FEV1
FVC
FEV/FVC
TLC
RV
DLCO
Asthma
Decreased More
than FVC
Decreased
Decreased
Increased
Increased
Normal
Emphysema
Decreased
Decreased
Decreased
Increased
Increased
Decreased(due to
destruction of
Alveolar wall)
COPD
Decreased
Decreased
Decreased
Increased
Increased
Normal if
underlying cause
is Bronchitis and
Decreased in
Emphysema
Interstitial Lung
Disease
Decreased
Decreased
Normal/Elevated
Decreased
Decreased
Decreased(Normal
in
Extraparenchymal
causes)
Pulmonary
Embolism
Normal
Normal
Normal
Normal
Normal
Decreased