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Finding Structure

Friedrich Miescher discovered DNA and isolated it in 1869. Phoebus Levene identified the base, sugar and phosphate units that make up DNA in the early 1900s. Oswald Avery showed DNA was the molecule that carries genetic information in 1944. James Watson and Francis Crick were not the first to study DNA's structure, building on prior work of Miescher, Levene and Avery to develop their 1953 double helix model of DNA structure.

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138 views1 page

Finding Structure

Friedrich Miescher discovered DNA and isolated it in 1869. Phoebus Levene identified the base, sugar and phosphate units that make up DNA in the early 1900s. Oswald Avery showed DNA was the molecule that carries genetic information in 1944. James Watson and Francis Crick were not the first to study DNA's structure, building on prior work of Miescher, Levene and Avery to develop their 1953 double helix model of DNA structure.

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Finding the structure ACTIVITAT TEMA ADN

Aquesta activitat us ensenyarà com va ser la història del descobriment de l'estructura de


la doble hèlix. per això haureu de navegar dins de la fantàstica pàgina www.dnai.org i
contestar una sèrie de senzilles preguntes. Les qüestions són senzilles, però les haures
de respondre a partir del que haureu llegit i escoltat en anglés. Tranquis que les pelis són
subtitulades. A més, sempre podreu "fardar" davant de la profe d'anglés)
Aquest treball l'haureu de presentar el dia 10 de sesembre (hi ferem l'examen si no
passa res) i podeu contestar en la llengua que més us agrade

Finding the Structure: pieces of the puzzle


Background

James Watson and Francis Crick are given credit for developing the three-dimensional structural model of
DNA used today. However, they were not the first to ask the question, “How is hereditary information
carried from one generation to the next?” or “How does it work?”
Throughout history, our understanding of science changes as small modifications are made to what is
known. Each discovery makes it possible for the next step in our understanding of scientific concepts to
occur. The Watson and Crick model of DNA would not have happened without the work done by Oswald
Avery, Phoebus Levene, and Friedrich Miescher.

Go to www.dnai.org > Code > Finding the Structure > problem


As you work through the problem section, record the specific contribution that each scientist made

Friedrich Miescher
Phoebus Levene
Oswald Avery

Solving the DNA puzzle

Other scientists working with DNA at the same time as Watson and Crick include Erwin Chargaff,
Rosalind Franklin, Linus Pauling, and Maurice Wilkins. The discoveries made by these individuals were
important in solving the DNA puzzle.

1. Obtain the file containing 17 puzzle pieces. (FILE: puzzle_ADN.jpg)


Examine the pieces and read through any information provided on them.
: 2. Go to www.dnai.org > Code > Finding the Structure > players
As you watch and listen to the videos and read the text, write the name of the scientist/s that select that
match the contributions each made to our understanding of DNA structure.
: 3. Before you make your final selection, work through the pieces of the puzzle section.
(www.dnai.org > Code > Finding the Structure > pieces of the puzzle)

: 4. Once your puzzle is finished, go to putting it together.


(www.dnai.org > Code > Finding the Structure > pieces of the puzzle)
Observe the animations.Try the base pairing interactive. (Hint: there are clues at the bottom of the
interactive to help you).
Questions
Explain why it would not have been possible for Watson and Crick to develop their DNA model without
the data from Franklin, Wilkins and Chargall?.

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