Debi P. Sarkar, C.V.

October, 2010

CURRICULUM VITAE

Name: Designation (Pay Scale):

DEBI PRASAD SARKAR Professor (Rs. 37,400/--Rs. 67,000/-), Former Head & Dean Rs. 50,440/- + Grade Pay Rs.10,000/Department of Biochemistry University of Delhi, South Campus, Benito Juarez Road, Dhaula Kuan, New Delhi-110021, INDIA Tel: (Off.) 91-11-24111967& 24114159 (Res.) 91-11-24113869, 9810432097 (mobile) Fax: 91-11-24110283, 24115270 and 24110876 Mobile: 9810696767 E.Mail : dpsarkar59@rediffmail.com dpsarkar59@gmail.com, debi.sarkar@south.du.ac.in 15th January, 1958 Male Married Dr. Neelam K. Sarkar Ms. Tanushree Sarkar

Present Basic Pay: Complete Postal Address, Telephone No., Fax No. and E.Mail:

Date of Birth: Sex: Marital Status: Name of Spouse: Name of Child:

Debi P. Sarkar, C.V. October, 2010

Educational Qualifications: Degree Subjects Year University Class

P.U. (Sc.) B.Sc. M.Sc.

Science Chemistry (Hons) Biochemistry

1974 1978 1980

Calcutta University Banaras Hindu University Banaras Hindu University

1st 1st 1st, Gold Medalist

Ph.D.

Biochemistry

1986

Calcutta University

Research/Training Experience : A Duration Position Institution Particulars of work done

1981-1985

JRF/SRF (DST/ CSIR)

Indian Institute of Chemical Biology, (CSIR) Calcutta.

Immunogenicity of Carbohydrate Determinants mediated through Liposomes. Liposome Mediated Drug Delivery. Liposomes as Immunomodulators, Drug Delivery using Liposomes Animal virus induced cell fusion. Entry Mechanism of Influenza virus.

1985-1986

SRF/ Research Dept. of Biochem. Associate University of Delhi, South Campus, New Delhi. Visiting Fellow Lab of Mathematical Biology, National Cancer Institute, NIH, Bethesda, Md 20892, U.S.A. Dept. of Biochemistry, University of Delhi, South Campus, New Delhi.

1986-1988

1988-1993

Lecturer

Teaching M.Sc (Biochemistry) students & Research. Honorary Lecturer, Jawaharlal Nehru University, New

Debi P. Sarkar, C.V. October, 2010

1993-1996

Senior Lecturer

-do-

Delhi. Teaching M.Sc (Biochemistry) Students & Research. -do-

1996-2002

Reader

-do-

2002-till date

Full Professor

-do-

-do-

MAY-AUG, 1989

ICRETT Awardee

LMMB, NIH/NCI, Bethesda, Md 20892, U.S.A. LMMB, NIH/NCI, Bethesda, Md 20892, U.S.A. LMMB, NIH/NCI, Md 20892, U.S.A.

Entry Mechanism of Influenza Virus.

OCT-DEC, 1990 MAY-AUG, 1991

Courtesy Associate Courtesy Associate

Entry Mechanism of Influenza Virus. Entry Mechanism of Influenza Virus.

MAY-JULY 1992

Courtesy Associate

LMMB, NIH/NCI, Bethesda, Md 20892, U.S.A. Division of Molecular Biology & Biochemistry, School of Basic Life Science, Univ. of Missouri, Kansas City, U.S.A. LMMB, NIH/NCI, Bethesda, Md 20892, USA and Division of Molecular Biology & Biochemistry, UMKC, USA. LMMB, NIH/NCI, Bethesda, Md 20892 USA.

Entry Mechanism of Influenza Virus.

JUNE-JULY 1993

Visiting Scientist

Influenza HA induced cell-cell fusion.

NOV-DEC 1994

Expert

Influenza HA induced cell-cell fusion.

JUNE-JULY 1995

Expert

Moloney Murine Leukemia Virus Envelope Protein

Debi P. Sarkar, C.V. October, 2010

Induced Membrane Fusion. June, 2006 till date Visiting Scientist Albert Einstein College of Medicine (AECOM), Bronx, NY, USA Pre-clinical Gene Therapy studies for TypeI Jaundice (NRDC, Govt. of India Sponsored)

B Worked as a Principal Investigator on a DST (Govt. of India) sponsored Research Project (1991-1995), entitled An Approach for Target Specific Delivery of Biologically active Molecules Using Virosomes and Fusogenic Vesicles. (Net Grant Value Rs. 21,79,000) Worked as a Principal Investigator on a CSIR (Govt. of India) sponsored Research Project (1992-1996), entitled Biophysical studies on the Formation and Dynamics of Viral Components and Evaluation of their Potential as Fusogenic Particulate Carriers for Introducing Biological Molecules into the Cells. (Net Grant Value Rs. 14,27,677) Worked as a Principal Investigator on a DBT (Govt. of India) sponsored Research Project w.e.f. Feb.1995, entitled Role of Glycosylation of Sendai Viral Fusion Protein--------Targeted Cytosolic and Nuclear Delivery System.(Net Grant Value Rs. 32,86,000) Worked as Co-Principal Investigator in a DBT (Govt. of India) sponsored Research Project w.e.f. Jan.1996, entitled Liposomal and Allied Lipid Vesicles--Development of Therapeutic Products.(Net Grant Value Rs. 32,81,000) Worked as a Principal Investigator on a CSIR (Govt. of India) sponsored Research Project w.e.f. Sept.1996, entitled Virosome-Mediated Delivery------Antisense Therapeutics.(Net Grant Value Rs. 22,00,000) Worked as a Principal Investigator on a DBT (Govt. of India) sponsored Research Project w.e.f March, 1998 entitled Development of Recombinant Sendai Virus---Therpeutic Importance (Net Grant value Rs. 32,00,000) Worked as a Principal Investigator on a CSIR (Govt. of India) sponsored Research Project, NMITLI programme, w.e.f. March, 2001 entitled Development of Advanced Drug Delivery Systems (Net Grant Value Rs. 72,00,000) till 2004. Working as a PI on a PANACEA BIOTEC Ltd., Lalru, Punjab sponsored Project entitled Virosome Mediated Anticancer Drug Deliverywef April, 2003 (Net Grant Value Rs. 46, 00,000).

Debi P. Sarkar, C.V. October, 2010

Worked as a PI on a DBT sponsored Project entitled Development of the Process for Mass Production of Targeted Delivery of Antigens Through Nanoparticles Using Sendai Virus System wef March, 2003 (Net Grant Value Rs. 62,00, 000) till 2006. Working as Co-PI with Dr. Saumitra Das, Dept. of Microbiology and Cell Biology, Indian Institute of Science, Bangalore-560012 on a DBT sponsored project entitled Inhibition of HCV RNA translational and replication using small RNAs wef November, 2005 (Net Grant Rs. 23.34 Lakhs). Working as Co-PI in a DBT sponsored Project with Prof. Subrata Sinha, Dept. of Biochemistry, AIIMS, New Delhi entitled Therapy of Infectious & Chronic Disesaes-Targeted Gene Delivery & Long Term Specific Modulation of Gene Expression wef. September, 2006, with a total amount of Rs. 93.43 Lakhs. Working as Co-PI in a DBT sponsored project with Dr. Sandeep Saxena, NII, New Delhi entitled Utilization of siRNA tools to study ----------- nanoparticle derived from Sendai virus wef 2008, with a total amount of Rs. 97.36 Lakhs. Working as Co-PI in a DBT sponsored project with Dr. SS Jana, IACS (DST), Kolkata entiltled Role of Nonmescle Myosin II in virus-cell fusion wef 2009, with a total budget of Rs. 8.82 Lakhs.

C Eight students (Ms. Sangeeta Bagai, Mr. Mukesh Kumar, Ms. Komal Ramani, Ms. Ruchika Nijhara, Mr. Siddhartha S. Jana, Santosh K. Verma, Indu Kohaar and Nishiraj Sharma) have been awarded Ph.D. (Biochemistry) degree, University of Delhi, under my supervision. Ira Surolia has submitted thesis under my supervision. Four students (working for Ph.D. degree), one SRF, one STA and one DST Fast Track Scientist are working with me in these projects.

D Established Collaborative Projects in the areas of: a)Viral spike glycoprotein induced cell fusion with Dr. Robert Blumenthal, Director, CCR Nanobiology Programme, NCI/NIH, Frederick, MD, U.S.A. b)Mechanism of Hepatitis B virus X protein mediated activation of signal transduction with Dr. Vijay Kumar, Scientist, International Center for Genetic Engineering and Biotechnology, New Delhi. c) Targeted delivery of bilirubin - UDP-glucoronosyl transferase(BUGT) gene in the Gunn rat model with Prof. Jayanta Roy-Chowdhury, MD, MCRP, Director, Gene Therapy Core, Albert Einstein College of Medicine, New York, USA in the area of Gene Therapy. d) Targeted delivery of HCV specific shRNA using Sendai virosomes both in vitro and whole animal (mouse model) with Prof. Saumitra Das, Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore.

Research Specialization / Major Scientific fields of interest:

Debi P. Sarkar, C.V. October, 2010

Molecular Virology, Cell Biology, Immunology, Biotechnology, Model Membranes & Drug/Gene Targeting. Short Term Training Attended: a) Completed courses on Recombinant DNA Methodology andHybridoma: Monoclonal Antibody Production, at Foundation for Advanced Education in Sciences. Inc., NIH, Bethesda. Md-20892, USA, Jan-March, 1988. b) Attended FEBS International Summer School on Immunology, 10-20thSept. 1984. Ionian Village, West Coast of Peloponese, Greece & Delivered a talk entitled Carrier and adjuvant role of Liposomes in eliciting sugar specific antibodies.

Awards: Awarded a Gold Medal from the Banaras Hindu University for standing first in the M.Sc. (Biochemistry) examination in 1980. Awarded a Travel Fellowship by the International Union of Biochemistry to attend the 13th International Congress of Biochemistry, Amsterdam, The Netherlands, August 25th-30th, 1985. Awarded an ICRETT Fellowship by the International Union Against Cancer to work in NCI/NIH, USA for 76 days from May 16th to August 1st, 1989. Awarded S. S. BHATNAGAR Prize in BIOLOGICAL SCIENCES, 1998. Conferred M. SREENIVASAYA MEMORIAL AWARD, by SBC, India, 2005 JC BOSE National Fellowship (DST) Award, September, 2010 Publications: 1. Sarkar, Debi P., Das, Pijush K. and Das, Manoj K: Antibody Induced Agglutination of Galactocerebroside Liposomes. Indian Journal of Experimental Biology, 20 : 522-524, 1982. 2. Sarkar, Debi P., Das, Pijush K., Bachhawat, Bimal K. and Das, Manoj K: The Adjuvant Role of Liposomes in Eliciting Antigalactosyl Antibodies. Immunological Communications, 11 : 175-188, 1982. 3. Das, Manoj K. and Sarkar, Debi P.: Interaction of Fab of Antigalactocerebroside Antibody with Galactocerebroside Liposomes. Immunology Letters,6: 223-226, 1983. 4. Sarkar, Debi P. and Das, Manoj K.: Immunogenicity of Galactosylated Liposomes. Immunological Communications, 13 : 5-13, 1984. 5. Sarkar, Debi P. and Das, Manoj K.: Properties of Antigalactosyl Antibodies Raised Through Liposomes. Indian Journal of Experimental Biology, 22 : 175-178, 1984. 6. Das, Manoj K., Roy, Samir K. and Sarkar, Debi P.: Characterization of Anti-NAcetyl-D-Glucosamine Antibodies Elicited through Haptenated Liposomes. Carbohydrate Research, 128 : 335-340, 1984. 7. Das, Manoj K., Bachhawat, Bimal K., Das, Pijush K. and Sarkar, Debi P.: Dual Role of Liposomes as Adjuvant and Carrier for the Production of Sugar Specific Antibodies. Proceedings of Indian Academy of Sciences (Chemical Sciences), 93 : 1111-1115, 1984.

Debi P. Sarkar, C.V. October, 2010

8. Sarkar, Debi P. and Das, Manoj K: The effect of Membrane Composition on the Immune Reactivity of Galactosylated Liposomes. Indian Journal of Biochemistry and Biophysics, 21 : 155-157, 1984. 9. Sarkar, Debi P. and Das, Manoj K: A Simple Procedure to Elicit Sugar Specific Antibodies Using Liposomes. Indian Journal of Biochemistry and Biophysics, 22 : 244-246, 1985. 10. Sarkar, Debi P. and Das, Manoj K: Binding of Antigalactosyl Antibody to Galactosylated Liposomes. Immunology Letters, 8 : 257-260, 1984. 11. Sarkar, Debi P. and Blumenthal, Robert: The Role of Target Membrane Structure in Fusion with Sendai virus. Membrane Biochemistry, 7 : 231-247, 1987/1988. 12. Morris, Stephen J., Sarkar, Debi P., White, Judith M. and Blumenthal, Robert: Kinetics of pH Dependent Fusion Between 3T3 Fibroblasts Expressing Influenza Hemagglutinin and Red Blood Cells: Measured by Dequenching of Fluorescence. J. Biol. Chem., 264 : 3972-3978, 1989. 13. Blumenthal, Robert, Puri, Anu, Sarkar, Debi P., Chen. Yi-der., Eidelman, Ofer and Morris, Stephen J.: Membrane Fusion Mediated by Viral Spike Glycoproteins in Cell Biology of Virus Entry, Replication and Pathogenesis Vol.90 pp 197-217, 1989 (eds. Compans, R., Helenius, Ari and Oldstone, M., Alam R. Liss Inc.). 14. Sarkar, Debi P., Morris, Stephen J., Eidelman, Ofer, Zimmerberg, Joshua and Blumenthal, Robert: Initial Stages of Influenza Hemagglutinin-Induced Cell Fusion Monitored Simultaneously by two Fluorescent Events: Cytoplasmic Continuity and Membrane Mixing. J. Cell Biol., 109 : pp 113-122, 1989. 15. Lowy, R. Joel, Sarkar, Debi P., Chen, Yider, Blumenthal, Robert: Observation of Single Influenza Virus-Cell Fusion and Measurement by Fluorescent Video Microscopy. Proc. Natl. Acad. Sci. (USA), 87 : 1850-1854, 1990. 16. Morris, Stephen, J., Sarkar, Debi P., Zimmerberg, Joshua and Blumenthal Robert: Kinetics of Viral Envelope Protein-Induced Cell Fusion by Continuous Monitoring of Fluorescent Dyes in Membrane Technology, 1989 (R. Verna, ed) Vol 64, pp 125135. Raven Press, New York. 17. Kaplan, Doron, Zimmerberg, Joshua, Puri, Anu, Sarkar, Debi P. and Blumenthal Robert: Single Cell Fusion Events Induced by Influenza Hemagglutinin:Studies with Rapid-Flow, Quantitative Fluorescence Microscopy. Exp. Cell. Res., 195 : 137-144, 1991. 18. Morris, Stephen, J., Zimmerberg, Joshua, Sarkar, Debi P. and Blumenthal Robert : Kinetics of Cell Fusion Mediated by Viral Spike Glycoproteins. Methods in Enzymology, 221 : Part B, 42-58, 1993. 19. Bagai, Sangeeta, Puri, Anu, Robert Blumenthal and Sarkar, Debi, P.: Hemagglutinin-Neuraminidase Enhances F Protein-Mediated Membrane Fusion of Reconstituted Sendai Viral Envelopes with Cells. J. Virol, 67 : 3312-3318, 1993. 20. Bagai, Sangeeta and Sarkar, Debi P.: Targeted Delivery of Hygromycin B Using Reconstituted Sendai Viral Envelopes Lacking Hemagglutinin-Neuraminidase. FEBS Lett., 326 : 183-188, 1993. 21. Bagai, Sangeeta and Sarkar, Debi P.: Fusion-Mediated Microinjection of Lysozyme into HepG2 Cells Through Hemagglutinin Neuraminidase-Depleted Sendai Virus Envelopes. J. Biol. Chem., 269 : 1966-1972, 1994.

Debi P. Sarkar, C.V. October, 2010

22. Bagai, Sangeeta and Sarkar, Debi P.: Reconstituted Sendai Virus Envelopes as Biological Carriers; Dual Role of F Protein in Binding and Fusion With Liver Cells. Biochim. Biophys. Acta, 1152 : 15-25, 1993. 23. Bagai, Sangeeta and Sarkar, Debi P.: Kinetics of Fusion With Cells of Reconstituted Sendai Virus Envelopes Lacking Hemagglutinin-Neuraminidase. Indian Journal of Biochemistry and Biophysics, 30 : 395-399, 1993. 24. Zimmerberg, Joshua, Blumenthal, Robert, Sarkar, Debi P., Curran, Michael and Morris, Stephen J.: Restricted Movement of Lipid and Aqueous Dyes Through Pores Formed by Influenza Hemagglutinin During Cell Fusion. J. Cell. Biol. 127 : 18851894, 1994. 25. Bagai, Sangeeta and Sarkar, Debi P.: Effect of Substitution of HemagglutininNeuraminidase with Influenza Hemagglutinin on Sendai Virus F Protein Mediated Membrane Fusion. FEBS Lett. 353 : 332-336, 1994. 26. Morris, Stephen J., Howard, Daniel E., Chang, Teng H., Sarkar, Debi P. and Blumenthal, Robert : Hemagglutinin-Catalyzed Cell-Cell Fusion: Kinetics of Initial Pore Formation from Video Rate Multi-Wavelength Fluorescence Microscopy. J. Microscopy Soc. of America. 1 : 47-54, 1995. 27. Lowy, R.Joel, Sarkar, Debi P., Whitnall, Mark H. and Blumenthal, Robert: Differences in Dispersion of Influenza Virus Lipids and Proteins During Fusion as Observed by Fluorescence Video Microscopy. Exp. Cell. Res. 216 : 411-421, 1995. 28. Kumar, Mukesh and Sarkar, Debi P.: F Protein Induced Fusion of Sendai Viral Envelopes with Mouse Teratocarcinoma Cells Through Lex-Lex Interaction. FEBS Lett. 391 : 17-20, 1996. 29. Blumenthal, Robert, Sarkar, Debi P., Durrell, Stewart, Howard, Daniel E. and Morris, Stephen J. : Dilation of the Influenza Hemagglutinin Fusion Pore Revealed by the Kinetics of Individual Cell-Cell Fusion Events. J.Cell Biol., 135: 63-71, 1996. 30. Ramani, Komal, Bora, Roop S., Kumar, Mukesh, Tyagi, Sandeep K. and Sarkar, Debi P.: Novel Gene Delivery To Liver Cells Using Engineered Virosomes. FEBS Lett., 404 : 164-168,1997. 31. Kumar, Mukesh, Hassan, M. Q., Tyagi, Sandeep K. and Sarkar, Debi P.: A 45,000Mr Glycoprotein in Sendai Viral Envelope Triggers Virus-Cell Fusion. J. Virol, 71 : 6398-6406, 1997. 32. Ramani, K., Hassan, M. Q., Venkaiah, B., Hasnain, S. E. and Sarkar, Debi P.: SiteSpecific Gene Delivery in vivo through Engineered Sendai Viral Envelopes. Proc. Natl. Acad. Sci. USA, 95: 11886-11890, 1998. 33. Nijhara, R., Jana, S. S., Goswami, S. K., Rana, A., Majumdar, S. S., Kumar, V., and Sarkar, Debi P. Sustained Activation of Mitogen-Activated Protein Kinases and AP1 by the Hepatitis B Virus X Protein in Mouse Hepatocytes in vivo. J. Virol. 75: 10348-10358, 2001. 34. Nijhara, R., Jana, S. S., Goswami, S. K., Kumar, V., and Sarkar, Debi P. An Internal Segment (residues 58 to 119) of the Hepatitis B Virus X Protein is Sufficient to Activate MAP Kinase Pathways in Mouse Liver. FEBS Lett, 504: 59-64, 2001. 35. Sarkar, Debi P., Ramani, K. and Tyagi, S. K. Targeted Delivery of Genes. Proc. Indian Natn Sci Acad. (PINSA), B68 No. 4, 315-332, 2002.

Debi P. Sarkar, C.V. October, 2010

36. Jana, S. S., Bharali, D. J., Mani, P., Maitra, A., Gupta, C. M. and Sarkar, Debi P. Targeted Cytosolic Delivery of Hydrogel Nanoparticles into HepG2 Cells Through Engineered Sendai Viral Envelopes. FEBS Lett, 515: 184-189, 2002 37. Verma, S. K., Mani, P., Sharma, N. R., Krishnan, A., Kumar, V. V., Reddy, B. S., Chaudhuri, A., Roy, R. P. and Sarkar, Debi P. Histidylated Lipid - Modified Sendai Viral Envelopes Mediate Enhanced Membrane Fusion And Potentiate Targeted Gene Delivery. J. Biol. Chem., 280, 35399-35409, 2005 38. Kohaar, I., Thakur, N., Salhan, S., Batra, S., Singh, V., Sharma, A., Sodhani, P., Das, B.C., Sarkar, Debi P. and Bharadwaj, M. TNF-308G/A polymorphism as a risk factor for HPV associated cervical cancer in Indian population. Cellular Oncology, 29, 249-256, 2007 39. Surolia, I., Chhiber, M., Sarkar, Debi P., and Sinha, S., Fibrillogenesis in Adan peptides is inhibited by biphenyl ethers. Biochim. Biophys. Res. Commun., 370, 681-686, 2008 . 40. Surolia, I., Sarkar, Debi P., and Sinha, S. Form and dimensions of aggregates dictate cytotoxicities of Danish dementia peptides. Biochim. Biophys. Res. Commun., 372,62-66, 2008 . 41. Surolia. I., Sinha, S., Sarkar, Debi P., Reddy, P. Y., Reddy G. B., and Surolia A., Concurrence of Danish dementia and cataract: Insights from the interactions of dementia associated peptides with eye lens -Crystallin. PloS One, 3, e2927, 2008 42. Krishnan, A., Verma, S. K., Mani, P., Gupta, R., Kundu S. and Sarkar Debi P. A histidine switch in hemagglutinin-neuraminidase triggers paramyxovirus-cell membrane fusion. Journal of Virology, 83, 1727-1741, 2009 43. Kohaar, I., Hussain, S., Thakur, N., Tiwari, P., Nasare, V., Batra, S., Singh, V., Bhambani, S., Das, B.C., Sarkar, Debi P., Bharadwaj, M. Association between HLA Class II alleles with HPV mediated Cervical Cancer in Indian women, Human Immunology, 70, 222-229, 2009 44. Subramanian, N., Mani, P., Roy, S., Sarkar, Debi P., and Das, S., Targeted delivery of hepatitis C virus specific shRNA in mouse liver using Sendai virosomes. Journal of General Virology, 90, 1812-1819, 2009. 45. Wang, X., Sarkar, Debi P., Mani, P., Steer, Clifford J., Chen, Y., Guha, C., Chandrasekhar, V., Chaudhuri, A., Roy-Chowdhury, N., Kren, Betsy T., RoyChowdhury, J., Long-term reduction of jaundice in Gunn rats by non-viral livertargeted delivery of Sleeping Beauty transposon. Hepatology, 50, 815-824, 2009. 46. Sharma, NR., Mani, P., Nandwani, N., Mishra, R., Rana, A. and Sarkar, Debi P., Reciprocal regulation of AKT and MAP Kinase dictates virus-host cell fusion. Journal of Virology, 84, 4366-4382, 2010. 47. Sivakumar Vadivel Gnanasundram, Prasanna Bhat, Prashant Mani, Partho Sarothi Ray, Debi P Sarkar and Saumitra Das, Small RNA derived from HCV IRES inhibits its translation and replication by interfering ribosome assembly, 2010 (Communicated)

Debi P. Sarkar, C.V. October, 2010

Patents: 1. Sarkar, Debi P. Ramani, Komal, Bora, Roop S., Kumar, Mukesh, and Tyagi, Sandeep K. : Process for Producing A Targeted Gene. US Patent Application Granted. Patent No. 5,683,866; Date. 4th Nov, 1997. 2. Debi P. Sarkar et. al. (2005) Process for producing modified reconstituted Sendai viral envelope specific for drug and/or gene delivery to liver cells Indian Patent Applications Filed. # 1003/Del/2005 dated 21/4/2005. PCT application filed, October, 2005 (PCT No. PCT/IN2006/000061 dated 6th Nov., 2009). USA Patent Application Published, Pub. No. US 2010/0047897 A1, dated 25th Feb., 2010

Books: 1. Sarkar, Debi. P., Ramani, K. and Tyagi, S.K. Targeted Gene Delivery by Virosomes. In a book chapter entitled "LIPOSOME METHODS AND PROTOCOLS" Edited by Subhash C. Basu and Manju Basu, Series Editor, John M. Walker, Humana Press Inc. Totowa, New Jersey, USA, ISBN 089603-845-9 (alk. paper) in "METHODS IN MOLECULAR BIOLOGY SERIES" Vol. 199 pp. 163-173, 2002. 2. Kumar, Vijay and Sarkar, Debi P., Hepatitis B Virus X Protein: StructureFunction Relationships and Role in Viral Pathogenesis in Handbook of Experimental Pharmacology/Transcription Factors Edited by Drs. Jorg Kaufmann, Atugen AG, Berlin, Germany, and S. Triezenberg, MSU, East Lansing, USA, vol. 166, pp. 377-407, SPRINGER-VERLAG , Germany, 2004. 3. Wang, X., Mani, P., Sarkar, Debi P., Roy-Chowdhury, N. and Roy-Chowdhury, J., Ex Vivo Gene Transfer into Hepatocytes in a book chapter entitled Hepatocyte Transplantation edited by Anil Dhawan and Robin D. Hughes (eds.), METHODS IN MOLECULAR BIOLOGY SERIES, Chapter 11, Humana Press, New Jersey, USA, vol. 481, 2009.

Places Where Work of Last Thirteen Years Has Been Referred/Cited:

Paper

Methods in Mol. Biol. (2002) 199 163

Name of the author who has cited Torchilin VP

Year of Publication 2005

Name of Journal

Volume

Page No.

Dimitrov DS

2004

Nature Reviews (Drug Discovery) Nature Reviews

145

109

10

Debi P. Sarkar, C.V. October, 2010

(Microbiology)

FEBS Lett (2002) 515 184

Jun L Flenniken ML Nayak S Verma SK Latha N Daemen T

2006 2006 2005 2005 2005 2005

Ma LY

2004

Biomaterial Chem. Biol. Angew. Chem. Int. Edit. J. Biol. Chem. Drug Design Reviews Online Adv. Drug. Deliver. Rev. Spectrochim. Acta. A

In Press 13 44 280 2 57

In Press 161 7686 35399 145 451

60

1865

J. Virol (2001) 75 10348

Tanaka Y Zhang X Verma SK Lwa SH Guo L Hsiang C-Y Guan J Bouchard MJ Gong M Parashar Mishra K Noh EJ

2006 2005 2005 2005 2005 2004 2004 2004 2004 2004 2004

Oncogene J. Med. Virol. J. Biol. Chem. Virology J. Life Sci. Tumor Biol. World J. Gastroentro. J. Virol. World Chinese J. Digesto. Virus Res. Biochem. & Biophy. Res. Comm. World Chinese J. Digesto. Virus Res. World Chinese J. Digesto. World Chinese J. Digesto. World Chinese J. Digesto. Rev. Med. Virol. World Chinese J. Digesto. World Chinese J.

25 77 280 2 77 25 10 78 12 105 319

633 374 35399 1869 313 3522 12725 2572 157 738

Ji D Wang J-C Ji D Ji D Dai Z-Y Singh M Cheng J

2004 2004 2003 2003 2003 2003 2003

12 102 11 11 11 13 11

1559 133 1959 1874 1349 243 925

11

Debi P. Sarkar, C.V. October, 2010

Cheng J Macdonald A Tanabe K Lian Z Cheng J Reddi H Jana SS Tanaka Y Yoo Y-G Gong M Parashar Mishra K Hung L Ji D Ji D Singh M Reddi H Verma SK Daemen T Kapczynski DR Kaneda Y Kapczynski DR Kapczynski DR Kaneda Y Ghosh S Jana SS Kowolik CM Johnson-Saliba M Rader DJ Ponimaskin EG Nijhara R Xingjiang X Nijhara R Ghosh SS Kaneda Y

2003 2003 2003 2003 2003 2003 2002 2006 2004 2004 2004 2004 2003 2003 2003 2003 2005 2005 2004 2003 2003 2003 2002 2002 2002 2002 2001 2001 2001 2001 2001 2001 2000 2000

Digesto. J. Biol. Chem. Anesthesiology Neoplasia World Chinese J. Digesto. Virus Genes FEBS Lett. Oncogene FEBS Lett. World Chinese J. Digesto. Virus Res. FEBS Lett. World Chinese J. Digesto. World Chinese J. Digesto. Rev. Med. Virol. Virus Genes J. Biol. Chem. Adv. Drug Deliver. Rev. Avian Dis. Curr. Drug Targets Avian Dis. Avian Dis. Mol. Ther. Mol. Ther. FEBS Lett. Mol. Ther. Curr. Drug Targets Nutr. Metab. Cardivas. Curr. Genomics FEBS Lett. Chinese J. Med. Genet. J. Virol. J. Hepatol. Adv. Drug.

11 278 98 3 11 26 515 25 577 12 105 560 11 11 13 26 280 57 48 4 47 47 6 6 515 5 2 11 2 504 18 75 32 43

888 17775 1147 229 472 227 184 633 121 2572 157 210 1959 1874 243 227 35399 451 332 599 578 272 219 5 184 762 371 40 261 59 59 10348 238 197

FEBS Lett (2001) 504 59

Proc. Natl. Acad. Sci. USA (1998) 95 11886

12

Debi P. Sarkar, C.V. October, 2010

Ponimaskin E Trigiante G Qian C Rouse RJD Drummond DC Suzuki K Fukuma T

2000 2000 2000 2000 2000 2000 2000

McCluskie MJ McCluskie MJ

1999 1999 2005 2005 2005 2004 2003 2003 2003 2003 2003 2002 2002 2002

FEBS Lett. (1997) 404 164

Verma SK Daemen T Kaneda Y Kapczynski DR Kaneda Y Kapczynski DR Kapczynski DR Roy I Oker-Blom C Kaneda Y Jana SS Kim HS

Johnson-Saliba M 2001 Nijhara R 2001 Kaneda Y 2000 Orellana A McCluskie MJ McCluskie MJ Tarahovsky YS 1998 Dimitrov DS J. Virol. (1997) 71 6398 Verma SK Plattet P Okano S 1997 2005 2005 2003

1999 1999 1999

Deliver. Rev. Virology Antiviral Res. J. Hepatol. Biotechniques Prog. Lipid Res. Gene Therapy Regulation Gene Therapy Regulation Microbes Infec. Clin. Rev. Immunol. J. Biol. Chem. Adv. Drug Deliver. Rev. Adv. Genetics Avian Dis. Curr. Drug Targets Avian Dis. Avian Dis. Int. J. Pharm. Method Enzymol. Mol. Ther. FEBS Lett. Cancer Gene Ther. Curr. Drug Targets FEBS Lett. Adv. Drug. Deliver. Rev. J. Biotechnol. Microbes Infec. Clin. Rev. Immunol. BiochemistryMoscow CELL J. Biol. Chem. Virology Gene Ther.

269 45 32 29 39 1 1 1 19 280 57 53 48 4 47 47 250 372 6 515 9 2 504 43

391 211 344 810 409 65 79 685 303 35399 451 307 332 599 578 272 25 418 219 184 173 371 59 197

75 1 19 63 91 280 337 10

209 685 303 607 721 35399 312 1381

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Debi P. Sarkar, C.V. October, 2010

Hong SK Moll M Jana SS Liang E Johnston ICD Rasmusson BJ Tomasi M Daemen T Hong SK Wagner M Laine RA Kumar M Melikyan GB

2002 2002 2002 1999 1999 1998 1998 2005 2002 1998 1997 1997 1996

FEBS Lett. (1996) 391 17

J. Micros. Soc. Am. (1995) 1 47 Exp. Cell Res. (1995) 216 411 J. Biol. Chem. (1994) 269 1966

J. Biochem. Mol. Biol. J. Virol. FEBS Lett. Pharmazie J. Virol. BBA- Mol. Cell Res. FEBS Lett. Adv. Drug Deliver. Rev. J. Biochem. Mol. Biol. Antiviral Res. Pure Appl. Chem. J. Virol. Biophys. J

35 76 515 54 73 1404 423 57 35 39 69 71 71

459 7174 184 559 6903 338 286 451 459 113 1867 6398 2680

Edidin M

1996

Curr. Top. Membr. J. Biol. Chem. J. Biochem. Mol. Biol. FEBS Lett. Cancer Gene Ther. J. Virol. J. Virol. J. Virol. FEBS Lett. Indian J. Biochem. Bio. J. Virol. Curr. Sci. India FEBS Lett. Sem. Liv.Dis. Hepatology Elswhere J. Biol. Chem. Adv. Drug Deliver. Rev. BBA-

43

Verma SK Hong SK Jana SS Kim HS Nijhara R Spiegel M Bitzer M Ramani K Swain PK Kumar M Rangarajan PN Kumar M Meijer DKF Basu SK &Roy Chowdhury J Verma SK Daemen T Watabe A

2005 2002 2002 2002 2001 1998 1997 1997 1997 1997 1996 1996 1995 1994

280 35 515 9 75 72 54 404 34 71 71 391 15 20

35399 459 184 173 10348 5296 5481 164 186 6398 360 17 202 1640

FEBS Lett. (1994) 353 352

2005 2005 1999

280 57 1416

35399 451 339

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Debi P. Sarkar, C.V. October, 2010

Kumar M Mizuguchi H J. Cell Biol. Melikyan GB (1994) 127 Pak CC 1885 Rex S White JM Monck JR Danieli T Gandin Y Melikyan GB Do BBABiomembranes (1993) 1152 15 Verma SK Daemen T Huckriede A Jana SS Cho JE Yu Y-C Mammen M Bitzer M Ramani K Kumar M Kumar M Kaneda Y Verma SK Kaneda Y Kaneda Y Jana SS Pachuk CJ Drummond DC Colosimo A Ramani K Kumar M Harris JD

1997 1996 1994 1996 1996 1995 1995 1996 1995 1995 1995 2005 2005 2003 2002 2001 1998 1998 1997 1997 1997 1996 2005 2005 2003 2002 2002 2000 2000 1998 1997 1997 1996

Biomembrane J. Virol. Biochem. Bioph. Res. Co. Biophys. J. BBA Biophys. Chem. Cold. Spr. Habor. Symp. Curr. Opin. Cell Bio. J. Cell Biol. J. Gen. Virol. J. Cell Biol. J. Gen. Physl.

71 218 71 1278 58 60 8 133 76 131 106 280 57 373 515 18 120 37 71 404 71 391 53 280 4 6 515 2 39 48 404 71 12

6398 402 2680 98 75 581 524 559 1541 679 783 & 803 35399 451 74 184 421 9979 2755 5481 164 6398 17 307 35399 599 219 184 188 409 221 164 6398 400

FEBS Lett. (1993) 326 183

J. Biol. Chem. Adv. Drug Deliver. Rev. Method Enzymol. FEBS Lett. J. Microencapsul. J.Am.Chem.Soc Angew Chem Int Ed J. Virol. FEBS Lett. J. Virol. FEBS Lett. Adv. Genetics J. Biol. Chem. Curr. Drug Targets Mol. Ther. FEBS Lett. Curr. Opin. Mol. Ther. Prog. Lipid Res. Acta Pharmaceutica FEBS Lett. J. Virol. Trends Genet.

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Debi P. Sarkar, C.V. October, 2010

Rangarajan PN Kumar M Dallocchio F Miller N J. Virol (1993) 67 3312 Verma SK Ohki S Kapczynski DR Ludwig K Rawat SS Kapczynski DR Hong SK Jana SS Kim HS Cobaleda C

1996 1996 1995 1995 2005 2004 2004 2003 2003 2003 2002 2002 2002 2002

Curr. Sci. FEBS Lett. Biochem. Bioph. Res. Co. FASEB J. J. Biol. Chem. J. Membrane Biol. Avian Dis. EMBO J. Mol. Membr. Biol. Avian Dis. J. Biochem. Mol. Biol. FEBS Lett. Cancer Gene Ther. Int. J. Biochem. Cell B. FEBS Lett. J. Virol. Methods J. Virol. Cloning J. Microencapsul. Virology Prog. Lipid Res. BBABiomembrane J. Virol. Langmuir J. Gen. Virol. Comp. Biochem. Phys. B Virology Biophys. J. FEBS Lett. Indian J. Biochem. Bio. J. Virol. J. Cell Biol. FEBS Lett. Biochem Bioph.

71 391 208 9 280 199 48 22 20 47 35 515 9 34

360 17 36 190 35399 73 332 3761 243 578 459 184 173 403

Nijhara R Wang ZM Nijhara R Markgraf K Cho JE Paterson RG Drummond DC Watabe A Dutch RE Longo ML Leyrer S Reyes-Leyva J

2001 2001 2001 2001 2001 2000 2000 1999 1998 1998 1998 1997

504 98 75 3 18 270 39 1416 72 14 79 118

56 53 10348 11 421 17 409 339 7745 2385 683 327

Bagai S Longo ML Ramani K Swain PK Kumar M Bagai S

1997 1997 1997 1997 1997 1996

238 73 404 34 71 135

283 1430 164 186 6398 73

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Debi P. Sarkar, C.V. October, 2010

Kumar M Tsujii E Bagai S Liu TM Ambrose MR Taira H Lamb RA Methods Enzymol. (1993) 221 42 J. Biol. Chem. (2005), 280, pp. 3539935409, Oct. 2005 Blumenthal R Zimmerberg J Do

1996 1996 1995 1995 1995 1995 1993 1996 1994 1993

Res. Co. J. Virol. J. Immunol. J. Infec. Dis. Arch. Virol. Virology

391 220 69 154 171 140 197 135 127 221

17 459 6712 3147 851 187 1 63 1885 99

J. Cell Biol Do Methods Enzymol. Biosci. Rep.

NM Rao & V Gopal

2006

26

301-324

Summary of Citation Index of last 13 years papers published by Prof. Debi P. Sarkar, Ph.D. from the Department of Biochemistry, University of Delhi South Campus

Total Number of Papers: 17 Total number of citations: 199 Maximum citations received by a paper: 35 Average citations per paper: 11.7 (Bagai et. al., J. Virol (1993) 67, 3312)

Abstract Presented in Meetings/Invited Talks: 1. Bagai, Sangeeta and Sarkar, Debi P. Noninvolvement of Hemagglutinin of Sendai Virus (HVJ) in Virosome-Cell Fusion. Poster Presented in the 59th Annual
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Debi P. Sarkar, C.V. October, 2010

Meeting of Society of Biological Chemists (INDIA), 27-29th December 1990, Udaipur. 2. Bagai, Sangeeta and Sarkar, Debi P. : Use of Sendai Virus Fusion Protein for the Intracellular Delivery of Biologically Active Molecules. Abstract Presented in the 4th National Symposium on Liposome Research, 1st-4th March, 1992, University of Delhi South Campus, New Delhi. 3. Bagai, Sangeeta and Sarkar, Debi P. : Reconstituted Sendai Virus Envelopes as Biological Carriers - Dual Role of F Protein in Binding and Fusion with Liver Cells. Poster Presented in the 61st Annual General Body Meeting of Society of Biological Chemists, India, 21st - 23rd December, 1992. CCMB, Hyderabad. 4. Bagai, Sangeeta and Sarkar, Debi P. : Fusion Mediated Microinjection of Bioactive Molecules in Liver Cells Through Hemagglutinin-Neuraminidase Depleted Sendai Virus Envelopes. Lecture (By Invitation) presented in 3rd International Symposium on Biochemical Role of Eukaryotic Cell Surface Macromolecules. 4th - 8th January 1993. Holiday Inn, Crown Plaza, New Delhi 5. Tyagi, Sandeep K., Kumar, Mukesh and Sarkar, Debi P. : Protease Activity Associated with F Glycoprotein of Sendai Virus : A Possible Role in Virus-Cell Fusion. Poster presented in the 16th International Congress of Biochemistry and Molecular Biology. New Delhi, India, Sep 19-22, 1994. 6. Bagai, Sangeeta and Sarkar, Debi P.: Dual Role of Sendai Virus F Glycoprotein in Binding and Fusion with Liver Cells. Delivered Lecture (By Invitation) in 23rd Annual Meeting, Society for Glycobiology, University of Notre Dame, USA. 9th12th November, 1994. 7. Invited by Prof D.Balasubramanian, Convenor, GRC 94 to attend and present research work in the Guha Research Conference, Rameswaram/Mandapam, Tamil Nadu. 28th Dec to 31st Dec 1994. 8. Kumar, Mukesh, Tyagi, Sandeep K. and Sarkar, Debi P.: Evidence For a Third Envelope Glycoprotein of Sendai Virus and Its Role in Membrane Fusion. Poster presented in the First ICGEB-UCI Virology Symposium. New Delhi, India, Feb 20th - 23rd, 1995. 9. Sarkar, Debi P.: Targeted Cytosolic Delivery of Drugs through Virosomes. Delivered Lecture (By Invitation) in Global Meet on Parasitic Diseases, 18-22nd March, 1996, Hotel Hyatt Regency, New Delhi. 10. Sarkar, Debi P. Novel gene delivery to liver cells both in vitro and in vivo using engineered virosomes, Invited Speaker in the workshop entitled The Cell Biology of Viral Entry NCI - FCRDC, Frederick, Md, USA, Sep21 - 24, 1997 11. Sarkar, Debi P. Targeted gene delivery (By Invitation), In fifth Chandigarh Symposium on New Biology, Chandigarh, Feb.6 - 7, 1998. 12. Sarkar, Debi P. Site - Specific Gene Delivery Both in vitro And in vivo Through Engineered Sendai Viral Envelopes (By Invitation) In Current Trends in Liposome Research : Dream to Reality, March 23 - 25, 1998, Dept of Pharmaceutical Sciences, Doctor Hari Singh Gour Vishwavidyalya, Sagar, MP 13. Parashar, B., Ramani, K., Kadakol, A., Roy Chowdhuri, N., Sarkar, Debi P. and Roy Chowdhury, J. Efficient Liver - Targeted Gene Delivery in vivo into UDP Glucuronosyltransferase - Deficient Gunn Rats Using the F-protein of the Hemagglutinating Virus of Japan, Poster presented in the 50th Annual Meeting of

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Debi P. Sarkar, C.V. October, 2010

the American Association for the Study of Liver Disease (AASLD), Wyndham Anatole Hotel, Dallas, Texas, USA, November 5 - 9, 1999. 14. Sarkar, Debi P. TARGETED CYTOSOLIC DELIVERY OF HEPATITIS X GENE INTO MOUSE HEPATOCYTES IN VIVO THROUGH SENDAI VIRAL ENVELOPES: MODULATION OF MITOGENIC SIGNALING CASCADES, Invited for Presentation in the workshop entitled 3rd Workshop on The Cell Biology of Viral Entry NCI - FCRDC, Frederick, MD, USA, May 05-08, 2002. 15. Sarkar, Debi P., Delivered a talk entitled Use of Viral Nanoparticles in Studying Role of Cell Signalling in Membrane Fusion, Invited Speaker in 2nd Annual Cancer Nanibiology Think Tank, May 24th, 2007, Organized by CCR Nanobiology Program, NCI - FCRDC, Frederick, MD, USA. Delivered Invited Lectures at Various Places: Centre for Cellular & Molecular Biology (CSIR), Hyderabad., National Institute of Immunology, Delhi., National Institutes of Health, Bethesda, MD, USA., University of Missouri at Kansas City, USA., University of Notre Dame, USA., Wright State University, Dayton, USA. Department of Biotechnology, Punjab University, Chandigarh (In Chandigarh Symposium on New Biology, 1992). Department of Biological Chemistry, The University of Michigan, USA, Cancer Research Institute, Bombay, BARC, Bombay, Seth G.S. Medical College, Bombay, National Chemical Laboratory, Pune, National Facility for Animal Tissue and Cell Culture, Pune, Institute of Microbial Technology, Chandigarh, Central Drug Research Institute, Lucknow (Annual Meeting of Society of Biological Chemists, 1995) and Jawahar Lal Nehru University. New Delhi, Invited speaker in the workshop entitled The cell biology of viral entry, 21st Sep97 - 24th Sep97, NCI - FCRDC, NIH, MD, USA, University of Calcutta, Indian Institute of Chemical Biology (CSIR), Calcutta. Indian Institute of Technology, Delhi. National Centre for Cell Science, Pune, Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, New York, USA. NIPER, Mohali, Chandigarh, North Western University, Evanston, Chicago, USA, McMaster University, Hamilton, Ontario, Canada, The Texas A&M University System Health Science Center College of Medicine, Temple, Texas, Cleveland Clinic Foundation, Boston University, University of North Dakota Administrative Experiences: Organized (as a Secretary) the 4th National Symposium on Liposome Research, 1st - 4th March, 1992, University of Delhi South Campus (UDSC), New Delhi. Organized (as a Convener) the 4th International Symposium on Cell Surface Macromolecules, 6th-10th January, 1996, National Institute of Immunology, New Delhi. Organised (as a Member) the 5th International Symposium on Cell Surface Macromolecules, 4th-8th January, 1999, Indian Institute of Science, Bangalore. Worked as Head, Department of Biochemistry (UDSC) wef 16th Aug.05 till 15th August, 2008 and Dean and Executive Council (EC) member DU, Faculty of Interdisciplinary & Applied Sciences, UDSC, New Delhi wef. 16th August, 2005 till Sep.06. Co-Convener, Guha Research Conference (GRC), 2008 at Gangtok, Sikkim

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Debi P. Sarkar, C.V. October, 2010

Fellowship/Membership: Elected, Fellow of The National Academy of Sciences, India (1996), International Union Against Cancer (Switzerland), Society of Biological Chemists, Life Member, # 749, year 1995 (India), Biophysical Society (USA), The New York Academy of Sciences (USA, By Invitation), Guha Research Conference (India, Elected, 1994), Molecular Immunology Forum (India, Elected). Elected, Fellow of The Indian Academy of Sciences (2007). Declared Elected, Fellow of the Indian National Science Academy (INSA), New Delhi, wef. 1st January 2011. Expert/Reviewer: Indian Journal of Biochemistry and Biophysics, CSIR-UGC National Eligibility Test of JRF/SRF/RA. Reviewer of research grant proposals for CSIR, DBT and DST, Govt. of India. Reviewer of research papers from FEBS Letters. Reviewer of research papers from Molecular Pharmaceutics USA. Reviewer of research papers from Molecular Membrane Biology, USA. Reviewer of research papers from BioTechniques, USA. Reviewer of research papers from "Antiviral Research", Belgium. Reviewer of research papers from Archaea, Canada. (Member, Editorial Review Board). Regional manuscript reviewer of PDA Journal of Pharmaceutical Science and Technology, USA. Elected member of the editorial board of Indian Journal of Biochemistry and Biophysics. Ph.D.Thesis(Biochemistry/Life Sciences)Examiner of Various Universities/Institutes viz. BHU, JNU, Jadavpur University, University of Mumbai, Cancer Research Institute, Mumbai, NII, NIPER, University of Pune, Osmania University, Hyderabad, Jamia Millia Islamia, New Delhi, NCCS, etc. Reviewer of research papers from International Medical Journal for Experimental and Clinical Research, Poland, USA. Reviewer of Research papers from BBA-Biomembrane, Elsevier Press. Member of the Special Committee of Center for Biotechnology, JNU, New Delhi. Member of the Academic Committee of ICGEB, New Delhi. Member of the Special Committee of SLS, JNU, New Delhi. Member of the Task Force on Fast Track Project, DST, New Delhi. Member, Academic Council, Delhi University, Delhi Member, Executive Council, Sep.05 to Aug.06, Delhi University, Delhi Member (#21220M, Regular, wef.1st Jan. to 31st Dec. 2006, By Invitation, Sponsored by Prof. Charles E. Samuel, UC, Santa Barbara, USA), American Society of Biochemistry and Molecular Biology (ASBMB), USA, 2005 Member, Task Force, RCGM, DBT, New Delhi Member, Task Force, Biotech Facilities and Infrastructure, DBT, New Delhi Member, Task Force, Basic Research in Modern Biology, DBT, New Delhi

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Debi P. Sarkar, C.V. October, 2010

Member, Thematic-Group on National S&T Human Resource Development, CSIR, for the formulation of Eleventh Five Year Plan. Dean, Faculty of Interdisciplinary & Applied Sciences, Delhi University South Campus, New Delhi, Sep.05 to Sep.06. Member, of the Academic Committee of CCMB (CSIR), Hyderabad Member, of the Academic Committee of IMTECH (CSIR), Chandigarh Member, of the RC of CIMAP (CSIR), Lucknow Reviewer of research papers from Journal of Infectious Diseases (The University of Chicago Press) Reviewer of research papers from Nanotechnology, IOP Publishing Limited Registered in England under Registration No 467514. Registered Office: Dirac House, Temple Back, Bristol BS1 6BE England Vat No GB 461 6000 84. Reviewer of research papers from Langmuir, ACS Publications. Member, Award Committee, SBC(I), India, 2007-08 Member, Planning and Monitoring Board of National Brain Research Centre (NBRC, DBT), Manesar, Gurgaon Expert Member, RAB/CSIR Member, Standing Committee on Recognized Research Institute, JNU Member, Course committee, IISER, Mohali, Chandigarh Member of the expert committee of CSIR Eng-42 RA/SRF selection Member, Editorial Board of Human Gene Therapy, MaryAnn Liebert Inc. Publishers, A Journal of European Society for Gene and Cell Therapy wef August 2009

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Debi P. Sarkar, C.V. October, 2010

References: INDIA Prof. Sandip K. Basu Emeritus Scientist (Professor of Eminence) National Institute of Immunology Aruna Asaf Ali Marg New Delhi - 110067 Tel : (011)-26717107/26741703 Fax : (011)-26741704 E.Mail : sandip@nii.res.in FOREIGN Dr. Robert Blumenthal Chief, LECB, Director, Nanobiology Programme National Cancer Institute - FCRDC National Institutes of Health Frederick, MD. 21702 - 1201 USA Tel : 301-846-1446 Fax : 301-846-5598 E.Mail : blumen@helix.nih.gov Prof. Ananda M. Chakrabarty Dept. of Microbiology & Immunology College of Medicine University of Illinois, E-704, Medical Sciences Bldg., 835, South Wolcott Ave., Chicago, IL. 60612-7344, USA Tel : 312-996-7470 Fax : 312-996-6415 E.Mail : ananda.chakrabarty@uic.edu Prof. Andreas Herrmann Humboldt-Universitat zu Berlin, Mathematisch-Naturwissenschaftliche Fakultat I, Institute fur Biologie/Biophysik, Berlin, Germany Email: andreas.herrmann@rz.hu-berlin.de & h1211dyz@rz.hu-berlin.de

Prof. Asis Datta Professor of Eminence Former Director/NIPGR & VC (JNU) Jawahar Lal Nehru University Campus New Delhi - 110067 Tel: (011)-26735119/26742750/26735179 Fax: (011)-26741759 E.Mail : asis_data@rediffmail.com and asis_data@nipgr.res.in Prof. D. Balasubramanian Director of Research Hyderabad Eye Research Foundation L.V. Prasad Eye Institute Road No. 2, Banjara Hills Hyderabad - 500 034 Tel : (040)-3543652 / 3608262 / 3548267 Fax : (040)-3548271 E.Mail : dbala@lvpeye.stph.net Prof. Avadhesha Surolia Director National Institute of Immunology Aruna Asaf Ali Marg New Delhi - 110067 Tel : (011)-26175002 & 26175008 Fax : (011)-26109433 & 26162125 E.Mail : surolia@nii.res.in E.Mail : surolia@mbu.iisc.ernet.in

Dr. Dimiter S. Dimitrov, PhD CCR Nanobiology Program Head, Protein Interaction Group, Senior Investigator, Building 469, Room 150B, NCI/NIH, Frederick, MD-21702-1201, USA, Tel: 301-846-1352, Fax: 301-8465598, Email: dimitrov@ncifcrf.gov

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Debi P. Sarkar, C.V. October, 2010

Prof. K. Muniyappa Anindya Dutta, M.D., Ph.D. Professor & Chairman Byrd Professor of Biochemistry & Department of Biochemistry Molecular Genetics Indian Institute of Science Professor of Pathology Bangalore-560 012 Jordan Hall 1240, Box 800733 Tel: 080-2360 0278, 2293 2235, Res: 080- University of Virginia Health Sciences 2360 1242, Fax: 080-2360 0814 Center Charlottesville, VA 22908, USA E. Mail : kmbc@biochem.iisc.ernet.in Tel:434-924-1227 Fax:434-924-5069 ad8q@virginia.edu

Prof. Ganes C. Sen, Ph.D. Chairman, Department of Molecular Genetics, NE20, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA, Tel: 216-444-0636, Fax: 216-4440513, Cell: 216-233-9869, Email: seng@ccf.org

RESERACH CONTRIBUTIONS OF PROF. DEBI P. SARKAR, DURING 1988TILL DATE, IN THE DEPARTMENT OF BIOCHEMISTRY, UNIVERSITY OF DELHI SOUTH CAMPUS, NEW DELHI, INDIA: Two types of reconstituted Sendai virus envelopes, F-virosomes containing only the fusion protein (F) and F, HN-virosomes containing both the F protein and the hemagglutinin-neuraminidase (HN) have been prepared by solubilization of the intact virus with Triton X-100 followed by its removal using SM2 Bio-Beads. We also prepared reduced F,HN-virosomes (F,HNred-virosomes), by treating the F,HN-virosomes with dithiothreitol and its subsequent removal by dialysis. We demonstrated the fusion of Fand F,HNred-virosomes with HepG2 and HeLa cells respectively, using an assay method

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