1. A drug increases cardiac output by 30% and decreases arterial pressure by 10%.
What is
the effect of the drug on vascular resistance?
A. No change
B. Increase
C. Decrease
2. An isolated cannulated vessel is perfused at a constant flow rate (ml/min) with a saline
solution. The driving pressure along the vessel is 2 mm Hg. After the application of a
vasoconstrictor, the vessel diameter is reduced by 50%. What new driving pressure is required
to keep the flow rate constant?
A. 4 mm Hg
B. 8 mm Hg
C. 16 mm Hg
D. 32 mm Hg
3. An arteriole with a resistance of 3 mm Hg/L/min divides into four capillary branches with
resistances of 2, 3, 1 and 6, respectively. These capillaries combine into a single venule with a
resistance of 1. Which of the following values most closely represents the total resistance of
this vascular bed?
A. 3.0
B. 4.5
C. 6.0
D. 7.5
4. The following data were obtained from an individual:
temperature = 980 F
pulse rate = 200 beats/min
mean arterial blood pressure = 85 mm Hg
oxygen consumption = 2 L/ min
pulmonary artery oxygen content = 100 ml/ L blood
aortic oxygen content = 200 ml/ L blood
coronary sinus blood oxygen content = 50 ml/ L blood
The cardiac output (L/min) of this person is:
A. 2
B. 10
C. 20
D. 25
E. 30
5. From the value of cardiac output that you just calculated you would expect that this individual
is:
A. sleeping
B. sitting at rest in a chair
C. exercising vigorously
D. hanging upside down
6. Given the data blow, what is the net filtration pressure (mm Hg) across this capillary wall?
Capillary hydrostatic pressure 44 mm Hg
Interstitial capsule hydrostatic pressure 9 mm Hg
Plasma osmotic pressure 28 mm Hg
Interstitial fluid osmotic pressure 0 mm Hg
A. – 5
B. 7
C. 25
D. 63
E. 81
(Ans: 1-C, 2-D, 3-B, 4-C, 5-C, 6-B)