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Flumazine

Silver sulfadiazine 1% cream, brand name Flumazine, is an antimicrobial cream used to prevent and treat wound sepsis in patients with second- and third-degree burns. It should be applied once or twice daily at a thickness of 1.5mm and has broad-spectrum antibacterial and antifungal properties. Potential side effects include transient leucopenia, burning sensation, skin rash, itching, skin necrosis, and discoloration with internal absorption over large or prolonged areas. It is contraindicated in those with hypersensitivity to silver sulfadiazine or pregnant patients approaching term.

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213 views2 pages

Flumazine

Silver sulfadiazine 1% cream, brand name Flumazine, is an antimicrobial cream used to prevent and treat wound sepsis in patients with second- and third-degree burns. It should be applied once or twice daily at a thickness of 1.5mm and has broad-spectrum antibacterial and antifungal properties. Potential side effects include transient leucopenia, burning sensation, skin rash, itching, skin necrosis, and discoloration with internal absorption over large or prolonged areas. It is contraindicated in those with hypersensitivity to silver sulfadiazine or pregnant patients approaching term.

Uploaded by

zimmerstyle09
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Generic Name: silver sulfadiazine 1%

Brand Name: FLUMAZINE


Classification: antimicrobial
Dosage: The burn areas should be covered with the cream at all time, it is applied once or twice daily to a thickness of
1.5 mm, dressings are not required, unless necessary.
Indication: wounds and burns
Action: It has a broad-spectrum activity against gram positive and gram negative bacteria including pseudomonas
aeruginose and against some yeasts and fungi.
Therapeutic Effect: Prevention and treatment of wound sepsis in patients with second- and third-degree burns.

Adverse Reaction/Side effect:


1. Transient leucopenia after 2-4 days from initial treatment, may occurs and subsides spontaneously.
2. Burning sensation, skin rash, itching, skin necrosis, and discoloration.
3. Internal absorption with discoloration of the skin and neuropathy, can occur if medicine is applied to a large
area of wounds over prolonged periods.
4. It rarely causes interstitial nephritis.

Contraindication:
1. Hypersensitivity to silver sulfadiazine.
2. Pregnant patients approaching or at term, premature infants and newborn infants during the first two months
of life.
Nursing Responsibilities:

 Prepare the medication as prescribed.


 Maintain sterility when preparing and administering the medication.
 Administer the medication as prescribed.
 Document the procedure and note the patient’s reaction
 Teach patient that virus transmission can occur during treatment. Tell patient that there may be some
discomfort with application.
 Teach patient that therapy should begin as soon as signs and symptoms appear. Tell patient to notify prescriber
if adverse reactions occur

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