Usefulness
This method is simple, easy and can be used for the majority of ABGs. It only addresses acid-base balance and considers just 3
values.
pH,
PaCO2
HCO3-
Step 1. Use pH to determine Acidosis or Alkalosis.
ph
< 7.35 7.35-7.45 > 7.45
Normal or
Acidosis Alkalosis
Compensated
Step 2. Use PaCO2 to determine respiratory effect.
PaCO2
< 35 35 -45 > 45
Tends toward Normal Tends toward
alkalosis acidosis
Causes high pH Causes low pH
Neutralizes low or Neutralizes high
pH pH
Compensated
Step 3. Assume metabolic cause when respiratory is ruled out.
You'll be right most of the time if you remember this simple table:
High pH Low pH
Alkalosis Acidosis
High PaCO2 Low PaCO2 High PaCO2 Low PaCO2
Metabolic Respiratory Respiratory Metabolic
If PaCO2 is abnormal and pH is normal, it indicates compensation.
o pH > 7.4 would be a compensated alkalosis.
o pH < 7.4 would be a compensated acidosis.
Step 4. Use HC03 to verify metabolic effectNormal
HCO3- is 22-26
Please note:Remember, the first three steps apply to the majority of cases, but do not take into account:
o the possibility of complete compensation, but those cases are usually less serious, and
o instances of combined respiratory and metabolic imbalance, but those cases are pretty rare.
"Combined" disturbance means HCO3- alters the pH in the same direction as the PaCO2.
High PaCO2 and low HCO3- (acidosis) or
Low PaCO2 and high HCO3- (alkalosis).