This document discusses pituitary disorders and their treatments. Pituitary hypofunction results from destruction or pressure on the pituitary cells in the pituitary fossa and can affect the anterior or posterior pituitary. Anterior pituitary macroadenomas cause anterior pituitary hormone failure when sufficient pressure occurs. Treatments for pituitary hyperfunction involve removing excess hormones. Trans-sphenoidal hypophysectomy is used to treat Cushing's disease and acromegaly but can cause pituitary hormone deficiencies. Medical treatment with dopamine agonists is the first-line approach for prolactinoma. Treatments for pituitary adenomas are outlined from most to least invasive.
This document discusses pituitary disorders and their treatments. Pituitary hypofunction results from destruction or pressure on the pituitary cells in the pituitary fossa and can affect the anterior or posterior pituitary. Anterior pituitary macroadenomas cause anterior pituitary hormone failure when sufficient pressure occurs. Treatments for pituitary hyperfunction involve removing excess hormones. Trans-sphenoidal hypophysectomy is used to treat Cushing's disease and acromegaly but can cause pituitary hormone deficiencies. Medical treatment with dopamine agonists is the first-line approach for prolactinoma. Treatments for pituitary adenomas are outlined from most to least invasive.
This document discusses pituitary disorders and their treatments. Pituitary hypofunction results from destruction or pressure on the pituitary cells in the pituitary fossa and can affect the anterior or posterior pituitary. Anterior pituitary macroadenomas cause anterior pituitary hormone failure when sufficient pressure occurs. Treatments for pituitary hyperfunction involve removing excess hormones. Trans-sphenoidal hypophysectomy is used to treat Cushing's disease and acromegaly but can cause pituitary hormone deficiencies. Medical treatment with dopamine agonists is the first-line approach for prolactinoma. Treatments for pituitary adenomas are outlined from most to least invasive.
This document discusses pituitary disorders and their treatments. Pituitary hypofunction results from destruction or pressure on the pituitary cells in the pituitary fossa and can affect the anterior or posterior pituitary. Anterior pituitary macroadenomas cause anterior pituitary hormone failure when sufficient pressure occurs. Treatments for pituitary hyperfunction involve removing excess hormones. Trans-sphenoidal hypophysectomy is used to treat Cushing's disease and acromegaly but can cause pituitary hormone deficiencies. Medical treatment with dopamine agonists is the first-line approach for prolactinoma. Treatments for pituitary adenomas are outlined from most to least invasive.
Pituitary disorders include several clinically important conditions
that arise because of hyperfunction. Prolactinomas, acromegaly and Cushings disease are discussed elsewhere in the Endocrine Disorders Chapter. Pituitary hypofunction results from destruction or pressure on the pituitary cells in the pituitary fossa. Hypofunction can affect the anterior or the posterior pituitary. Anterior pituitary macroadenomas cause anterior pituitary hormone failure when sufficient pressure occurs. Posterior pituitary failure is less common, and other causes are more likely. Treatment of pituitary hyperfunction involves removing the excess hormone. Trans-sphenoidal hypophysectomy is the treatment of choice in Cushings disease and acromegaly, but can result in deficiency of pituitary hormones. Medical treatment is the firstline approach in prolactinoma, because the lactotroph hyperplasia that causes the problem regresses with dopamine agonists. Such medical treatment has no effect on other pituitary cells. Treatments for pituitary adenoma are shown in Figure 1, in the order that they should be undertaken until the patient is cured.
