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4.2. Kuliah Program Baru Hookworm

This document discusses hookworm, its etiology, pathogenesis, clinical manifestations, treatment, and prognosis. It identifies the main species that cause hookworm infections in humans as Ancylostoma duodenale and Necator americanus. It describes the hookworm lifecycle and notes that larvae can penetrate the skin, migrate through the lungs, and attach to the intestinal mucosa, causing anemia and potential cardiac failure. Symptoms include ground itch, cough, fever, and abdominal pain. Treatment involves oral anthelmintics like mebendazole or albendazole, with repeat treatment in 2 weeks and iron supplements for anemia. Prognosis is generally good if treated before complications arise.

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0% found this document useful (0 votes)
40 views9 pages

4.2. Kuliah Program Baru Hookworm

This document discusses hookworm, its etiology, pathogenesis, clinical manifestations, treatment, and prognosis. It identifies the main species that cause hookworm infections in humans as Ancylostoma duodenale and Necator americanus. It describes the hookworm lifecycle and notes that larvae can penetrate the skin, migrate through the lungs, and attach to the intestinal mucosa, causing anemia and potential cardiac failure. Symptoms include ground itch, cough, fever, and abdominal pain. Treatment involves oral anthelmintics like mebendazole or albendazole, with repeat treatment in 2 weeks and iron supplements for anemia. Prognosis is generally good if treated before complications arise.

Uploaded by

Bombom
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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HOOKWORM

(Cacing tambang)
ETIOLOGY:
ANCYLOSTOMA DUODENALE
NECATOR AMERICANUS
(Intestinal Helminthiasis)

N. americanus & A. duodenale


Intensitas

NA RTGT

RTGT AD

Ringan

< 2.000

< 7.000

Sedang

2000-7000

7000 35.000

Berat

> 7.000

> 35.000

Prepaten

7 mgg

6 mgg

RTGT

80

50-80

Live span

3-5 th

1-6 th

Isapan darah/hr.ekor

0,05 cc

0,15 cc

Cara infeksi

Oral, enteral, perkutaneus,


intest.otoinfeksi

Oral, perkutaneus,

Telur/induk.hari

6000-10.000

15.000-20.000

Habitat

Duod + jejun

Jej + ilem prox

dewasa
esofagus
Telur (200 rb/hr/induk)
tertelan

Tinja
Tanah

Naik ke trakea

Larva rabditiform

Life cycle

Sal. Napas > besar


Menembus alveoli

Larva filariform

Paru

Menembus kulit
Aliran darah

Jantung kanan

ETIOLOGY
Ankylostoma :
A. duodenale
N. amerikanus
(pembunuh org Amerika)
A. ceylanicum
A. malayanum
A. braziliensis
A. caninum

PATHOGENESIS
- FILARIFORM LARVAY MAY CAUSE A RASH AT THE SITE WHERE THEY
PENETRATE THE SKIN.
- LARVAL MIGRATION IN THE LUNGS EVOKES AN INFLAMMATORY
RESPONSE, PETECHIAL HEMORRHAGE, AND EPITHELIAL CELL
PROLIFERATION
- ATTACHMENT OF WORMS BY THEIR BUCCAL CAVITY LEADS TO
MUCOSAL INJURY ANEMIA CARDIAC FAILURE

CLINICAL MANIFESTATIONS (1)


SYMPTOMS
- GROUND ITCH PRURITIC
- COUGH
- LOW GRADE FEVER
- ANOREXIA
- DIARRHEA
- VAGUE ABDOMINAL PAIN
- ULCER-LIKE EPIGASTRIC SYMPTOMS

TREATMENT (1)
A. GENERAL MEASURES
1. RE-TREATMENT AT 2 WEEKS INTERVALS
2. IF ANEMIA IS PRESENT
- ORAL FERROUS SULFATE
- DIET: HIGH PROTEIN & VITAMINS 3 MONTHS

TREATMENT (2)
B. SPESIFIC MEASURES:
- PYRANTEL PAMOATE, SINGLE DOSE, 10 MG/KGBW (MAX. 1 GR)
- MEBENDAZOLE: 2X 100 MG/DAYLY FOR 3 DAYS OR SINGLE DOSE
500 MG
- AL BENDAZOLE: ORALLY ONCE 400 MG, FOR 2-3 DAYS
- THIABENDAZOLE: CUTANEOUS LARVA MIGRANS; 15% OINTMENT
FOR 3 DAYS
- TETRACHLORETHYLENE, 0,1 MG/KGBW (MAX. 5 ML) TAKEN
WHEN FASTING IN CAPSULES. ALLOW FOOD 3 H LATER, REPEAT
AT 4-DAY
- BEPHENIUM HYDROXYNAPHTHOATE, 5 G TID 1 DAY.

PROGNOSIS
IF IT IS RECOGNIZED BEFORE COMPLICATION
APPEAR COMPLETE RECOVERY AFTER TEATMENT

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