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Nafarin

Nafarin is a sympathomimetic amine used to treat urinary incontinence and relieve symptoms of allergic disorders like asthma and hay fever. It works as a vasoconstrictor in the nasal passages and respiratory tract by stimulating alpha- and beta-adrenergic receptors. Common side effects include dry mouth, urinary retention, sweating, anxiety and irregular heartbeat. It should be used cautiously in patients with hypertension, heart or lung disease, diabetes or thyroid problems.

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4K views2 pages

Nafarin

Nafarin is a sympathomimetic amine used to treat urinary incontinence and relieve symptoms of allergic disorders like asthma and hay fever. It works as a vasoconstrictor in the nasal passages and respiratory tract by stimulating alpha- and beta-adrenergic receptors. Common side effects include dry mouth, urinary retention, sweating, anxiety and irregular heartbeat. It should be used cautiously in patients with hypertension, heart or lung disease, diabetes or thyroid problems.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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Brand Name: Nafarin

Generic Name: Phenylpropanolamine HCl


Indications: urinary incontinence, relive symptoms of some allergic disorders such as asthma and
hay fever.
Drug Classification: Sympathomimetic
Mechanism of Action: The phenylpropanolamine HCl is a sympathomimetic amine with a
chemical structure and pharmacological actions similar to the ephedrine, but with
fewer central stimulant effects. It is a vasoconstrictor with decongestant action on
the nose and upper respiratory tract mucous membranes. It directly and indirectly
stimulates the a- and b-adrenergic receptors. It exerts this last action by allowing the
norepinephrine liberation (noradrenaline) from its storage sites. Its action on the a-
receptors in the respiratory tract mucosa produces vasoconstriction, which results in
the decrease of the mucosa edema and the consequent increase of the nasal air flow.
Dosage: Adults 25 mg at 4-hr intervals or 50 mg at 8-hr intervals, as indicated.
Children 6-12 yr: 25 mg at 8-hr intervals; 2-6 yr: 12.5 mg q 8 hrs; elixir: 20 mg/ml.
Special Precautions: elderly, hypertension, cardiovascular disease, hyperthyroidism, diabetes,
prostatic enlargement, tricyclic antidepressants.
Pregnancy Risk Category: C
Adverse Reactions:
GI: dry mouth
GU: urinary retention
Derm: sweating, cold extremities
CNS: anxiety, restlessness, insomia
CV: heartbeat irregularities
Contraindications: Patients with high blood pressure, overactivity of the thyroid gland, coronary
heart disease or diabetes, or who are taking antidepressant drugs
Forms: Sustained-release capsules, dilute syrup, (topical) nasal or throat spray, elixir.
Nursing Responsibilities:
 Administer the medication with a full glass of water after a meal or snack. The
tablet can be broken in half. However, the whole or half tablet should be
swallowed whole.
 Assess for kidney disease, heart disease, lung disease, asthma, emphysema,
high blood pressure, an overactive thyroid, diabetes, glaucoma, prostate
trouble, depression, any allergies of the patient.
 Caution patient not to exceed recommended doses.

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