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Influence of Clinical, Physical, Psychological, and Psychophysical Variables on Treatment Outcomes in Somatic Tinnitus Associated With Temporomandibular Pain: Evidence From a Randomized Clinical Trial

Pain Pract. 2021 Jan;21(1):8-17. doi: 10.1111/papr.12919. Epub 2020 Jun 4.

Abstract

Objective: To assess the influence of clinical, psychological, and psychophysical variables on treatment outcomes after application of exercise combined with education with/without manual therapy in people with tinnitus associated with temporomandibular disorder (TMD).

Methods: A secondary analysis of a clinical trial was performed investigating the effectiveness of including cervico-mandibular manual therapy into an exercise combined with education program in 61 subjects with TMD-related tinnitus. Clinical outcomes including tinnitus severity and tinnitus-related handicap were assessed at 3 and 6 months post-intervention. Patients were assessed at baseline for clinical (tinnitus severity, tinnitus-related handicap, quality of life), physical (range of motion), psychological (depression), and psychophysical (pressure pain thresholds [PPTs]) variables that were included as predictors.

Results: The regression models indicated that higher scores of tinnitus severity at baseline predicted better outcomes 3 and 6 months post-intervention (explaining 13% to 41% of the variance) in both groups. Higher scores of tinnitus-related handicap at baseline predicted better outcome of tinnitus-related handicap (45% variance) in the manual therapy with exercise/education group. Lower PPTs over the temporalis muscle at baseline predicted poorer clinical outcomes (10.5% to 41% of the variance) in both groups. Other predictors were sex and quality of life (6.7% variance) in the manual therapy group and PPTs over the masseter muscle (5.8% variance) in the exercise/education group.

Conclusion: This study found that baseline tinnitus severity and localized PPT over the temporalis muscle were predictive of clinical outcomes in individuals with TMD-related tinnitus following physical therapy. Other predictors (eg, sex, quality of life) were less influential.

Keywords: manual therapy; outcome; temporomandibul0061r pain; tinnitus.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Exercise Therapy / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Musculoskeletal Manipulations / methods
  • Patient Education as Topic
  • Quality of Life
  • Temporomandibular Joint Disorders / complications*
  • Temporomandibular Joint Disorders / psychology*
  • Temporomandibular Joint Disorders / rehabilitation*
  • Tinnitus / etiology*
  • Tinnitus / psychology*
  • Tinnitus / rehabilitation*
  • Treatment Outcome