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Use of recreational drug 1,3 Dimethylamylamine (DMAA) [corrected] associated with cerebral hemorrhage

Ann Emerg Med. 2012 Oct;60(4):431-4. doi: 10.1016/j.annemergmed.2012.04.008. Epub 2012 May 9.

Abstract

Dimethylamylamine (DMAA) was a forgotten pharmaceutical that was patented in 1944 as a nasal decongestant. DMAA has recently gained popularity as a dietary supplement, with claims of effectiveness as an athletic performance enhancer and weight loss aid. It is also sold as a recreational stimulant drug. DMAA is a sympathomimetic and potent pressor agent. This report describes 3 cases of cerebral hemorrhage in adults after the use of DMAA. The status of this substance as a synthetic or naturally occurring compound is also discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / diagnostic imaging
  • Brain / drug effects
  • Cerebral Hemorrhage / chemically induced*
  • Cerebral Hemorrhage / diagnostic imaging
  • Ethylamines / adverse effects*
  • Female
  • Humans
  • Illicit Drugs / adverse effects*
  • Male
  • Neuroimaging
  • Subarachnoid Hemorrhage / chemically induced
  • Subarachnoid Hemorrhage / diagnostic imaging
  • Substance-Related Disorders / complications*
  • Substance-Related Disorders / diagnostic imaging
  • Tomography, X-Ray Computed
  • Young Adult

Substances

  • Ethylamines
  • Illicit Drugs
  • N,N-dimethylethylamine