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Search Results (324)

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Keywords = self-stigma

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12 pages, 290 KiB  
Article
Exploring the Impact of Stigma on Health and Wellbeing: Insights from Mothers with Lived Experience Accessing Recovery Services
by Lydia Lochhead, Michelle Addison, John Cavener, Steph Scott and William McGovern
Int. J. Environ. Res. Public Health 2024, 21(9), 1189; https://doi.org/10.3390/ijerph21091189 - 6 Sep 2024
Viewed by 1077
Abstract
Stigmatisation is the process by which an individual is devalued based on their attributes, characteristics, and/or behaviour, with this often leading to prejudice, social and health-related harms, active discrimination, and microaggressions. The aim of this paper is to show how social harms can [...] Read more.
Stigmatisation is the process by which an individual is devalued based on their attributes, characteristics, and/or behaviour, with this often leading to prejudice, social and health-related harms, active discrimination, and microaggressions. The aim of this paper is to show how social harms can occur and how stigma is damaging to the health and wellbeing of a person in recovery. To do so, we focus on the harms that arise from the internalisation of labels that mothers who use drugs encounter in a treatment and recovery setting whilst in active recovery, and how this stigmatisation can manifest negative self-beliefs. Qualitative data was used from two semi-structured focus groups involving females with lived experience of substance use (n = 13). A reflexive thematic analysis approach was used to analyse the interview transcripts, and three themes were identified: (1) the enduring nature of stigma; (2) gender disparity and the need for mothers- and women-only spaces; and (3) stigma as a barrier to services and wellbeing. Findings revealed the enduring nature of stigma amongst mothers who were in active recovery, with women feeling judged more harshly than men and experiencing pressure to live up to a “good mother” ideal whilst in recovery. This paper demonstrates that mothers in recovery are still stigmatised and, as a consequence, approach services with increased sensitivity, with stigma often resulting in disengagement or reluctance to access healthcare settings. We conclude that staff in health, social, and primary care settings need to develop a strong therapeutic alliance with mothers in recovery and promote anti-stigma approaches in their practice, in order to mitigate stigma and reduce harms to health and wellbeing. Full article
(This article belongs to the Section Behavioral and Mental Health)
19 pages, 380 KiB  
Review
Unravelling Migraine Stigma: A Comprehensive Review of Its Impact and Strategies for Change
by Javier Casas-Limón, Sonia Quintas, Alba López-Bravo, Alicia Alpuente, Alberto Andrés-López, María Victoria Castro-Sánchez, Javier Amós Membrilla, Cristian Morales-Hernández, Nuria González-García and Pablo Irimia
J. Clin. Med. 2024, 13(17), 5222; https://doi.org/10.3390/jcm13175222 - 3 Sep 2024
Viewed by 623
Abstract
Migraine-related stigma is a pervasive issue impacting nearly half of chronic migraine patients, with significant consequences for their quality of life, disability and mental health. Despite its profound effects, migraine stigma remains under-recognised in both clinical practice and research. This narrative review explores [...] Read more.
Migraine-related stigma is a pervasive issue impacting nearly half of chronic migraine patients, with significant consequences for their quality of life, disability and mental health. Despite its profound effects, migraine stigma remains under-recognised in both clinical practice and research. This narrative review explores the three primary types of stigmas affecting migraine patients: public, structural and internalised. Public stigma involves negative societal attitudes and stereotypes that trivialise the condition. Structural stigma is reflected in policies that restrict access to necessary care and resources. Internalised stigma occurs when patients absorb these negative views, leading to self-blame and diminished self-worth. Addressing these different types of stigmas is crucial for improving the understanding, diagnosis and treatment of migraine. Educational efforts, advocacy and policy reform are essential strategies in this context. A deep understanding of stigma is vital for developing effective interventions that enhance clinical management and patient quality of life. Ultimately, reducing stigma can lead to better health outcomes and a more comprehensive approach to migraine care. Full article
11 pages, 316 KiB  
Brief Report
What Women with HIV Know about Heart Health and Cardiovascular Risk and Intervention Preferences
by Lunthita M. Duthely, Sanjana Satish, Sapna A. Kedia, Lilliana Vilchez, Priscilla T. Valls, Michaela E. Larson, Carolina Cruzval O’Reilly, Vanessa Hurtado, Maria Camila Bernal, Karla Inestroza, Nicholas F. Nogueira, Tiffany R. Glynn, Mariano J. Kanamori and Claudia A. Martinez
Int. J. Environ. Res. Public Health 2024, 21(9), 1149; https://doi.org/10.3390/ijerph21091149 - 29 Aug 2024
Viewed by 522
Abstract
Cardiovascular disease (CVD) is a significant health concern influenced by various determinants. Stigma and resilience have emerged as factors in CVD development and management. Women with HIV (WWH) have higher CVD rates than women without HIV. To improve cardiovascular health for WWH, a [...] Read more.
Cardiovascular disease (CVD) is a significant health concern influenced by various determinants. Stigma and resilience have emerged as factors in CVD development and management. Women with HIV (WWH) have higher CVD rates than women without HIV. To improve cardiovascular health for WWH, a comprehensive understanding of how these factors interact, the understanding about individual awareness and willingness to engage in risk-reduction interventions are needed. Methods: As part of a study examining CVD risk among WWH aged >35 years old, 90-min focus groups were conducted (May 2022) in the English language. Focus groups aimed to elicit participants’ CVD risk knowledge and potential prevention strategies. Transcripts underwent a qualitative analysis. Results: Nineteen WWH participated in three focus groups. Participants experienced the following: (a) enacted stigma related to their HIV diagnosis (e.g., family, church member, healthcare staff); (b) a recent event (e.g., hospitalization of self/family, death in family, chest pain) triggered both heart health-promoting lifestyle changes and suboptimal health behaviors (e.g., COVID-19 pandemic: unhealthy snacking). Participants wanted to obtain more knowledge (“on a mission”) about CVD risk. In total, 100% expressed willingness to take medication or embark on other lifestyle changes to prevent future CVD events. Although participants identified preventative heart health behaviors (e.g., eating healthy foods; exercising; limiting stress, substances, and smoking), misconceptions were also identified (e.g., “catching” heart disease). Conclusions: Understanding the interplay of the different factors related to heart health is needed both at the provider and the patient level to inform interventions that reduce CVD risk amongst racial/ethnic minoritized women with HIV, living in the Southern region of the US. Full article
(This article belongs to the Special Issue Women Living with HIV)
12 pages, 281 KiB  
Article
“They Can’t Possibly Understand What I’m Going Through”: Female Farmers’ Perspectives on Barriers to Care in Georgia
by Noah Hopkins, Lauren Ledbetter Griffeth, Chase Reece and Christina Proctor
Int. J. Environ. Res. Public Health 2024, 21(9), 1130; https://doi.org/10.3390/ijerph21091130 - 27 Aug 2024
Viewed by 1142
Abstract
The purpose of this study was to explore female farmers’ perspectives on barriers to engaging with resources for physical and mental healthcare faced by agriculture producers in the state of Georgia. In-depth interviews were conducted with female farm owners and managers (n [...] Read more.
The purpose of this study was to explore female farmers’ perspectives on barriers to engaging with resources for physical and mental healthcare faced by agriculture producers in the state of Georgia. In-depth interviews were conducted with female farm owners and managers (n = 16) across the state. Interviews were recorded and transcribed, and researchers coded interviews separately before thematic analysis was used to identify common themes. Three primary themes were identified: (i) formal healthcare challenges, (ii) stigma, and (iii) cultural norms. Formal healthcare challenges included time constraints, healthcare costs, and a lack of cultural competence from healthcare providers. Both community and self-stigma were identified as barriers to engaging with mental health resources. Cultural norms that acted as a barrier to care included the prioritization of farm operations, self-reliance, pride, and the minimization of health concerns. Interviewees identified gender differences in the impact of stigma and cultural norms, reporting that these sociocultural barriers were more prominent among older, male producers. Central to many of these barriers is the concept of ‘farm identity’, where farmers’ commitment to their operations consistently trumped concerns about physical or mental health. Future efforts to improve health outcomes among farmers should utilize the concept of farm identity as a guide for tailoring interventions and improving cultural competence among rural healthcare providers. Full article
12 pages, 355 KiB  
Article
Somebody to Lean on: Understanding Self-Stigma and Willingness to Disclose in the Context of Addiction
by Qing Ma, Christopher R. Whipple, Övgü Kaynak, Erica Saylor and Weston S. Kensinger
Int. J. Environ. Res. Public Health 2024, 21(8), 1044; https://doi.org/10.3390/ijerph21081044 - 8 Aug 2024
Viewed by 605
Abstract
Substance use self-stigma is a barrier to treatment and can negatively impact individuals’ well-being and treatment engagement. Given the mixed findings in previous research and the limited specific investigation into the concept of self-stigma within the context of opioid misuse, examining factors associated [...] Read more.
Substance use self-stigma is a barrier to treatment and can negatively impact individuals’ well-being and treatment engagement. Given the mixed findings in previous research and the limited specific investigation into the concept of self-stigma within the context of opioid misuse, examining factors associated with self-stigma in the context of opioid use disorder (OUD) is warranted. The current study examines the influence of individual-level factors (race, sex, urban/rural status, support group attendance) on self-stigma and willingness to disclose opioid use. Data for this study were from a larger study of OUD-related stigma among adults in Pennsylvania, U.S. The current study included participants who indicated a personal past or current history with OUD were included (n = 84). Exploratory factor analysis and multiple indicators, multiple causes (MIMIC) model were used to explore the associations between demographic factors (i.e., sex, age, race/ethnicity, urban/rural status), attendance at mutual support groups, and self-stigma factors. Results indicated that sex and attendance at mutual support groups significantly predicted levels of self-stigma. Women and individuals with no previous experience attending mutual support groups endorsed lower levels of self-stigma. Additionally, attendance at mutual support groups predicted willingness to self-disclose past and present opioid use. Individuals who reported no history of attending mutual support groups demonstrated less willingness to disclose past and present OUD use compared to participants who were support group attendees. The current research findings enhance the understanding of OUD-related self-stigma by examining its relationship with individual-level factors, disclosure, and attendance to mutual support groups. The results offer insights into the influence of sex and support group attendance on self-stigma and disclosure. These findings have significant clinical implications for developing future interventions and promoting health policy changes. Full article
(This article belongs to the Special Issue 3rd Edition of Stigma, Health and Wellbeing)
23 pages, 1606 KiB  
Article
Addressing the Syndemic Relationship between Lymphatic Filariasis and Mental Distress in Malawi: The Potential of Enhanced Self-Care
by Carrie Barrett, John Chiphwanya, Dorothy E. Matipula, Janet Douglass, Louise A. Kelly-Hope and Laura Dean
Trop. Med. Infect. Dis. 2024, 9(8), 172; https://doi.org/10.3390/tropicalmed9080172 - 31 Jul 2024
Cited by 1 | Viewed by 897
Abstract
Lymphatic filariasis (LF) causes disfiguring and disabling lymphoedema, which can lead to mental distress and requires life-long self-care treatment. This study applies syndemic theory to understand the biosocial relationship between LF and mental distress in Malawi. Using in-depth qualitative methods, we critically evaluate [...] Read more.
Lymphatic filariasis (LF) causes disfiguring and disabling lymphoedema, which can lead to mental distress and requires life-long self-care treatment. This study applies syndemic theory to understand the biosocial relationship between LF and mental distress in Malawi. Using in-depth qualitative methods, we critically evaluate experiences of mental distress and LF through 21 life-history interviews, to narrate experiences from the perspective of persons affected by LF, and to understand how enhanced self-care (ESC) for lymphoedema management disrupts the syndemic relationship. Complementary key informant interviews with Ministry of Health LF programme staff were conducted to further understand intervention and health system delivery. All interviews were recorded, transcribed, and translated, and then subject to thematic analysis. Our findings suggest that for persons affected by LF in Malawi, before being trained in ESC, absent referral pathways, inequalities in healthcare provision or available treatment, and limited knowledge of the condition (LF) drove the syndemic of LF and mental distress. Distress was often exacerbated by stigma and social exclusion, and shaped by intersections of gender, generation, poverty, and extreme climate conditions. We argue that addressing the syndemic suffering associated with LF and mental distress through interventions which center the needs of persons affected is critical in effective and equitable LF care delivery. Full article
(This article belongs to the Special Issue An Update on Syndemics)
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<p>A Model for Understanding the Syndemic of LF and Mental Distress in the Context of Malawi.</p>
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<p>Chimwemwe’s story.</p>
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<p>Gracious’ story.</p>
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14 pages, 707 KiB  
Review
Strategies for Coping with Occupational Trauma: A Scoping Review of the Police Officer Context
by Mantji Juliah Modula, Ellen Mokgobola Mathapo-Thobakgale, Champion N. Nyoni and Ronelle Jansen
Int. J. Environ. Res. Public Health 2024, 21(7), 921; https://doi.org/10.3390/ijerph21070921 - 15 Jul 2024
Viewed by 969
Abstract
Background: Occupational trauma is heightened among police officers due to their exposure to physical, biological, chemical, and psychological hazards. Sustained occupational trauma results in mental illness among members of the police, which is a public health issue of concern. This study aimed to [...] Read more.
Background: Occupational trauma is heightened among police officers due to their exposure to physical, biological, chemical, and psychological hazards. Sustained occupational trauma results in mental illness among members of the police, which is a public health issue of concern. This study aimed to report a scoping review of the literature on strategies employed by police officers for coping with occupational trauma around the globe. Methods: A search string, formulated from the review question of what is known about the strategies of police officers for coping with occupational trauma, was used to search for articles from databases. A total of 588 hits were screened against inclusion criteria, resulting in 36 full-text studies between 1983 and 2022 being included in this review. Data were extracted using a standardised data extraction tool. The multi-step process was used to analyse the extracted data, integrating quantitative and qualitative approaches. Results: From this review, ‘adaptive coping mechanisms’, involving confrontation; ‘maladaptive coping mechanisms’, such as self-isolation, distancing and substance use; ‘resilience’, relating to mental preparation, and ‘seeking support systems’ from family, colleagues and professionals reflected the strategies used by police officers to cope with occupational trauma. Social stigma related to mental health disorders impacts the strategies used by police officers to cope with occupational trauma. Conclusions: the police management and healthcare practitioners must collaborate towards providing constructive environments that support and strengthen police officers’ strategies for coping with occupational trauma. Full article
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<p>PRISMA Flow diagram of included studies (adapted from Moher, Liberati, Tetzlaff, Altman, and The PRISMA Group (2009)).</p>
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15 pages, 251 KiB  
Article
“Exercise… to Me, It’s Freedom”: Motivation, Support, and Self-Management to Keep Physically Active with Parkinson’s Disease: A Qualitative Study
by Leanne Ahern, Catriona Curtin, Suzanne Timmons, Sarah E. Lamb and Ruth McCullagh
Geriatrics 2024, 9(4), 92; https://doi.org/10.3390/geriatrics9040092 - 11 Jul 2024
Viewed by 888
Abstract
The benefits of exercise have been widely explored among people with Parkinson’s (PwP). Exercise can improve non-motor (fatigue, pain, sleep, etc.) and motor features (balance, muscle strength, gait speed, etc.), maintain function, as well as prevent disease progression. Although the benefits are well [...] Read more.
The benefits of exercise have been widely explored among people with Parkinson’s (PwP). Exercise can improve non-motor (fatigue, pain, sleep, etc.) and motor features (balance, muscle strength, gait speed, etc.), maintain function, as well as prevent disease progression. Although the benefits are well known, PwP continue to show difficulty adhering to physical activity and exercise. This study aims to explore motivation to exercise, support, and self-management needs among people with Parkinson’s, their family members, and physiotherapists. Purposeful and maximum-variation sampling methods (age, sex, geographical setting, and disease severity) were employed. PwP and family members were recruited through physiotherapy services and local support groups. Twelve semi-structured interviews with PwP and two group interviews, one with family members (n = 4) and one with physiotherapists (n = 5), were conducted. Interview guides were informed by patient–public input and a recent systematic review. Interviews were recorded, transcribed, and analysed using thematic analysis informed by the Grounded Theory methodology. Four common themes emerged: (1) The value of an intrinsic connection with exercise, for which there are challenges. A greater connection to exercise led to long-term adherence. (2) Adapting exercise to the needs and preferences of a person is essential. Preferred exercises and environments were mixed, with differences emerging between sexes. (3) Physiotherapists’ aim to only maintain physical function led to frustration. Limited self-management opportunities, stigma, and dehumanisation were discussed. (4) Non-motor symptoms, stigma, fear, and determination as well as apathy, pain, and low mood were discussed. Exercise provided physical, emotional, and social rewards. Supports are necessary; however, challenges arise when PwP’s motivations are mismatched to family members’ and physiotherapists’ goals. Co-created goals, tailored to their preferences, and exercise plans with supported self-management are recommended. Full article
(This article belongs to the Special Issue Physical Activity and Exercise in Older Adults)
12 pages, 249 KiB  
Article
Understanding Internalized Stigma’s Role in Sex-Specific Suicidal Ideation among Individuals with Bipolar Disorder
by Martina D’Angelo and Luca Steardo
J. Clin. Med. 2024, 13(14), 4000; https://doi.org/10.3390/jcm13144000 - 9 Jul 2024
Viewed by 1101
Abstract
Background: The experience of stigma can exert a profound impact on the mental health and well-being of individuals with bipolar disorder (BD). Our study explores which factors of internalized stigma are associated with suicidal ideation and how they differ between the two [...] Read more.
Background: The experience of stigma can exert a profound impact on the mental health and well-being of individuals with bipolar disorder (BD). Our study explores which factors of internalized stigma are associated with suicidal ideation and how they differ between the two sexes in a clinical sample of BD patients. Methods: The study follows a cross-sectional study design, employing the Clinical Global Impression for Bipolar Patients (CGI-BP) to evaluate the overall severity of illness and the alteration in patients affected by bipolar disorder, the Internalized Stigma of Mental Illness (ISMI) assessing self-stigma among individuals experiencing mental disorders, and the Columbia Suicide Severity Rating Scale (C-SSRS) identifying and assessing individuals vulnerable to suicide. Descriptive analyses, analysis of variance (ANOVA), and logistic regression analysis were conducted, and 344 BD subjects were recruited. Results: Our ANOVA results revealed a significant association between sex and suicide across ISMI sub-items (p = 0.000). Logistic regression analysis comprised three phases: Discrimination was consistently significant across all phases (p < 0.001), while Alienation and Stereotype emerged as additional predictors of suicide in later phases of the analysis (p < 0.001). Conclusions: Our study contributes to the growing body of literature on internalized stigma, sex, and suicidality among individuals with bipolar disorder. Early intervention programs and prevention strategies are needed. Full article
(This article belongs to the Section Mental Health)
10 pages, 253 KiB  
Article
Religious/Spiritual Abuse, Meaning-Making, and Posttraumatic Growth
by Sarah Perry
Religions 2024, 15(7), 824; https://doi.org/10.3390/rel15070824 - 8 Jul 2024
Viewed by 1620
Abstract
While religion and spirituality (R/S) have been broadly studied for their positive mental health impacts, instances of abuse within religious or spiritual contexts remain under-researched. This scoping review aims to elucidate how individuals experiencing such abuse navigate their trauma, find meaning, and foster [...] Read more.
While religion and spirituality (R/S) have been broadly studied for their positive mental health impacts, instances of abuse within religious or spiritual contexts remain under-researched. This scoping review aims to elucidate how individuals experiencing such abuse navigate their trauma, find meaning, and foster posttraumatic growth (PTG). The research was conducted using a scoping review methodology as a guide, and 10 articles were selected based on predefined inclusion and exclusion criteria. Synthesizing these articles revealed the following three central themes: recognizing abuse, relaying one’s story, and redefining spirituality. Survivors often face disbelief and stigma, hindering their ability to process their experiences. However, narrative sharing enables many to reclaim agency and healing through validation and the integration of the narrative into one’s life story. Additionally, survivors often transform spirituality, shifting from rigid frameworks to more nuanced and flexible understandings of the Divine and self. These findings underscore the importance of trauma-informed, spiritually sensitive clinical approaches that validate survivors’ experiences, facilitate narrative sharing, and support spiritual redefining. Future research must address knowledge gaps, including the development of improved assessment tools, exploration of effective treatment strategies, and the unifying of terms to better support survivors’ healing journeys and promote meaning-making and PTG in the aftermath of R/S abuse. Full article
(This article belongs to the Special Issue Spirituality, Resilience and Posttraumatic Growth)
22 pages, 320 KiB  
Article
“I Can’t Get No Satisfaction”—Psychosocial Aspects and Awareness of Negative Impacts in Chemsex Users: Results from an Anonymous Online Survey
by Marcus Gertzen, Sinan Karcher, Johanna Schwarz, Cornelia Rosenberger, Moritz Strasburger, Andrea Rabenstein, Anna-Martina Strasser, Ulrich Palm and Tobias Rüther
Brain Sci. 2024, 14(7), 666; https://doi.org/10.3390/brainsci14070666 - 29 Jun 2024
Viewed by 620
Abstract
Chemsex is the interplay of substance use by men who have sex with men (MSM) in sexual contexts. The minority stress model and the identity process theory are explanatory models. In this study, we investigated whether (i) differences in certain psychosocial aspects (i.e., [...] Read more.
Chemsex is the interplay of substance use by men who have sex with men (MSM) in sexual contexts. The minority stress model and the identity process theory are explanatory models. In this study, we investigated whether (i) differences in certain psychosocial aspects (i.e., shame, aspects of queer identity, and sexual self-concepts) exist between chemsex users and non-users, and (ii) which factors influence an awareness of negative impacts in chemsex users. We conducted an anonymous, cross-sectional, online survey, including sociodemography, sexual history, history of substance use, validated scales for shame-proneness, aspects of queer identity, and sexual self-concepts. Our analysis comprised descriptive statistics, t-tests, Spearman’s correlations, and a multiple linear regression model. We recorded a total of 3257 datasets with 107 chemsex users. Chemsex users showed higher rates for risky sexual behavior. Values for shame proneness, more negative aspects of queer identity, and sexual self-concepts were elevated in chemsex users with an awareness of negative impacts. Sexual anxiety, intravenous substance use, and having had a difficult process coming out were significant predictors of feeling negative impacts. Aspects of shame, queer identity aspects, and sexual self-concepts play an important role in the field of chemsex. Different explanatory models seem to be relevant for different subgroups of chemsex users. Chemsex users with an awareness of a problem were particularly vulnerable and distressed but had the highest motivation for change. Prevention, counseling, and care might profit from the inclusion of these aspects. Further anti-stigma campaigns and a specialization of the healthcare system are needed. Registration: DRKS00022336, date: 29th of October, 2020. Full article
(This article belongs to the Special Issue Psychiatry and Addiction: A Multi-Faceted Issue)
13 pages, 616 KiB  
Article
Fear of Food in Gastrointestinal Disease: A Framework Based on the Interpreted Experiences of Adults with Diverticular Disease
by Skye Marshall, Fiona Eberhardt, Phoebe Dalwood, Megan Crichton, Xueying Tang, Russell Canavan and Dianne P. Reidlinger
Dietetics 2024, 3(2), 214-226; https://doi.org/10.3390/dietetics3020017 - 19 Jun 2024
Viewed by 722
Abstract
The patient voice is missing from the evidence regarding the dietary management of diverticular disease. This study aimed to determine the patient experiences of imposed dietary restrictions during the medical treatment of acute, uncomplicated diverticulitis. An Interpretive Phenomenological Analysis methodology guided participant selection, [...] Read more.
The patient voice is missing from the evidence regarding the dietary management of diverticular disease. This study aimed to determine the patient experiences of imposed dietary restrictions during the medical treatment of acute, uncomplicated diverticulitis. An Interpretive Phenomenological Analysis methodology guided participant selection, data collection, and the data analysis of a qualitative interview study. Four interviews were conducted with adults admitted to hospital with acute, uncomplicated diverticulitis. Six themes were interpreted. Five themes were found to inter-relate as a cycle, which was embedded within a driving theme of ‘corrupted diet-disease knowledge of patients, family, and healthcare providers’. The cycle commenced with a theme of ‘fear of food’, which was followed by the theme of an ‘internal locus of control with rigid constraint’. ‘Loss of culture and social stigma’ ensued, which led to ‘vulnerability amid self-perceived failure’, and finally ‘overshadowed psychological pain’. The cycle recommenced with a renewed fear of food. The thematic phenomenon of the ‘Fear of Food in Gastrointestinal Disease Framework’ was developed. Adults with diverticular disease and at least one hospitalisation for acute, uncomplicated diverticulitis were interpreted to experience a cyclical thematic phenomenon represented by the ‘Fear of Food in Gastrointestinal Disease Framework’. Further qualitative research is required to evaluate the transferability of the framework to other conditions. Full article
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<p>The ‘Fear of Food in Gastrointestinal Disease Framework’ representing the downward spiral-like cyclical thematic phenomenon interpreted as the experiences of patients placed on restrictive diets during inpatient treatment for acute, uncomplicated diverticulitis. T, theme. Solid arrows, dominant relationship. Dashed lines/arrows, divergent and/or complex relationships.</p>
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17 pages, 1096 KiB  
Article
Transcriptome Analysis of Stigmas of Vicia faba L. Flowers
by Inés Casimiro-Soriguer, David Aguilar-Benitez, Natalia Gutierrez and Ana M. Torres
Plants 2024, 13(11), 1443; https://doi.org/10.3390/plants13111443 - 23 May 2024
Viewed by 725
Abstract
Pollination in angiosperms depends on complex communication between pollen grains and stigmas, classified as wet or dry, depending on the presence or absence of secretions at the stigma surface, respectively. In species with wet stigma, the cuticle is disrupted and the presence of [...] Read more.
Pollination in angiosperms depends on complex communication between pollen grains and stigmas, classified as wet or dry, depending on the presence or absence of secretions at the stigma surface, respectively. In species with wet stigma, the cuticle is disrupted and the presence of exudates is indicative of their receptivity. Most stigma studies are focused on a few species and families, many of them with self-incompatibility systems. However, there is scarce knowledge about the stigma composition in Fabaceae, the third angiosperm family, whose stigmas have been classified as semidry. Here we report the first transcriptome profiling and DEGs of Vicia faba L. styles and stigmas from autofertile (flowers able to self-fertilize in the absence of manipulation, whose exudate is released spontaneously) and autosterile (flowers that need to be manipulated to break the cuticle and release the exudates to be receptive) inbred lines. From the 76,269 contigs obtained from the de novo assembly, only 45.1% of the sequences were annotated with at least one GO term. A total of 115,920, 75,489, and 70,801 annotations were assigned to Biological Process (BP), Cellular Component (CC), and Molecular Function (MF) categories, respectively, and 5918 differentially expressed genes (DEGs) were identified between the autofertile and the autosterile lines. Among the most enriched metabolic pathways in the DEGs subset were those related with amino acid biosynthesis, terpenoid metabolism, or signal transduction. Some DEGs have been related with previous QTLs identified for autofertility traits, and their putative functions are discussed. The results derived from this work provide an important transcriptomic reference for style-stigma processes to aid our understanding of the molecular mechanisms involved in faba bean fertilization. Full article
(This article belongs to the Special Issue Advances in Legume Crops Research)
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<p>Gene ontology (GO) functional classification of the <span class="html-italic">V. faba</span> transcriptome obtained from stigma and style samples. Histogram of the main transcripts annotated to specific GO categories: Biological Processes, Cellular Components, and Molecular Function. The <span class="html-italic">x</span>-axis represents the GO term, and the <span class="html-italic">y</span>-axis represents the number of genes annotated.</p>
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<p>Metabolism pathway assignments of the downregulated (red, left) and upregulated (blue, right) differentially expressed genes (DEGs) in AF vs. AS based on the Kyoto Encyclopedia of Genes and Genomes (KEGGs). The enrichment degree is calculated compared to the number of genes for a certain category present in <span class="html-italic">Medicago truncatula</span> in the KOBAS-i database.</p>
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10 pages, 326 KiB  
Article
The Role of Attachment Anxiety and Avoidance in Predicting Proximal Minority Stressors among Gay and Lesbian People in Italy
by Tommaso Trombetta, Maria Noemi Paradiso, Fabrizio Santoniccolo and Luca Rollè
Int. J. Environ. Res. Public Health 2024, 21(6), 655; https://doi.org/10.3390/ijerph21060655 - 21 May 2024
Cited by 1 | Viewed by 1117
Abstract
As has been widely documented, minority stress affects the psychosocial well-being of gay and lesbian people. Recently, researchers have turned their attention to psychological factors that may influence the level of minority stress experienced, in order to explain individual differences in perceptions of [...] Read more.
As has been widely documented, minority stress affects the psychosocial well-being of gay and lesbian people. Recently, researchers have turned their attention to psychological factors that may influence the level of minority stress experienced, in order to explain individual differences in perceptions of proximal minority stressors. The present research aimed at assessing the effect of attachment avoidance and anxiety on levels of perceived stigma and internalized homonegativity. A total of 163 participants who self-identified as lesbian or gay (Mage = 32.56, SD = 10.87) were recruited and responded to the self-report questionnaires. Two multiple regression models were applied to assess the association between adult attachment and perceived stigma and internalized homonegativity. Results showed a positive association between attachment anxiety and avoidance and internalized homonegativity, as well as between attachment avoidance and perceived stigma. The emerging results demonstrate the impact of attachment anxiety and avoidance on proximal minority stressors and provide useful data for interventions addressing lesbian and gay people aimed at promoting security-based strategies of affect regulation and positive representations of self and others, which in turn may reduce the level of proximal minority stressors experienced and promote psychosocial well-being. Full article
16 pages, 2695 KiB  
Article
FASD: The Living Experience of People with Fetal Alcohol Spectrum Disorder—Results of an Anonymous Survey
by Emily Hargrove, C. J. Lutke, Katrina Griffin, Myles Himmelreich, Justin Mitchell, Anique Lutke and Peter Choate
Disabilities 2024, 4(2), 332-347; https://doi.org/10.3390/disabilities4020022 - 8 May 2024
Viewed by 2666
Abstract
Fetal Alcohol Spectrum Disorder (FASD) is considered a lifelong disability that has been framed with neurobiological descriptions focused on the brain. These are important features but fail to tell the story of living with FASD. By surveying those with FASD, this work expanded [...] Read more.
Fetal Alcohol Spectrum Disorder (FASD) is considered a lifelong disability that has been framed with neurobiological descriptions focused on the brain. These are important features but fail to tell the story of living with FASD. By surveying those with FASD, this work expanded upon prior survey work which illustrated a multitude of early-onset physiological issues occurring at rates much higher than is typical of the general population. The current project, again using an anonymous survey methodology, sought to open up other direct experiences to better understand the complexity of living with FASD. An anonymous online survey was used to gather data on adversity in childhood, schooling, employment, housing and finances, and involvement with the criminal justice system, as well as relationships and parenting. Results indicate high levels of adversity throughout the life span; vulnerability to manipulation, which is connected to involvement in the criminal justice system; struggles with housing; economic instability; and struggles maintaining employment, as well as difficulties with social and familial relationships. Systemic stigma was also identified. Suggestions are offered to inform others on how support can be enhanced and targeted with a goal of improving quality of life, as well as dealing with self-imposed stigma. The survey was developed by adults living with FASD who have served as a long-standing advocacy and educational group influencing policy and practice in the field. Full article
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<p>Having connections to people with FASD who are acting as pro-social supports at a peer level is an important informal linkage that can be sustained over time.</p>
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<p>Examining the exposure to ACEs across various caregiving environments. Respondents may have answered for one, two, or three living situations. (Mental health included depression, suicide, exhaustion or other mental health issues).</p>
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<p>Exposure to interpersonal violence within the home.</p>
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<p>Sexual abuse reported by respondents. As indicated in the chart, 44 individuals reported sexual abuse in both categories.</p>
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<p>Adversity of physical abuse and sexual assault—interpersonal violence. Numbers may vary from <a href="#disabilities-04-00022-f004" class="html-fig">Figure 4</a> due to varying response rates.</p>
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<p>The behaviors reported linked to manipulation.</p>
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<p>The evolution of the dialogue of self-stigma. (Source: ALC FASD Changemaker authors).</p>
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