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Search Results (5,202)

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11 pages, 544 KiB  
Article
Secondhand Smoke Exposure and Its Impact on Pediatric Lung Function, Aerobic Fitness, and Body Mass: Evidence from a Cross-Sectional Study
by Ivan Pavić, Iva Topalušić, Tamara Poljičanin, Ozana Hofmann Jaeger, Sara Žaja and Asja Stipić Marković
Children 2024, 11(10), 1250; https://doi.org/10.3390/children11101250 - 17 Oct 2024
Viewed by 225
Abstract
Background: Several studies have documented the detrimental impacts of secondhand smoke (SHS) exposure to a range of pediatric respiratory conditions, including asthma, bronchitis, and reduced lung function. The aim of the study was to investigate the influence of SHS exposure on lung function, [...] Read more.
Background: Several studies have documented the detrimental impacts of secondhand smoke (SHS) exposure to a range of pediatric respiratory conditions, including asthma, bronchitis, and reduced lung function. The aim of the study was to investigate the influence of SHS exposure on lung function, physical fitness, and body mass index (BMI) in children aged 10 to 14 years. Methods: This cross-sectional study included children aged 10 to 14 years at the Elementary School “Trilj” in Trilj, Croatia. Data on SHS exposure were collected using a questionnaire. Antropometric and spirometry measurements were performed. Physical fitness was assessed using the shuttle run (BEEP) test. Results: This study included 157 children, 89 (56.69%) boys and 68 (43.31%) girls. Children exposed to every day SHS in households had significantly lower values of forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC, peak expiratory flow (PEF) (p < 0.001) and higher z-score BMI levels (p = 0.018) in comparison to unexposed children. Logistic regression showed that children unexposed to SHS had higher odds for better results in the BEEP test (OR 62.45, 95% CI 21.26–179.24, p < 0.001). Children with poorer physical fitness, expressed by lower BEEP score levels, had significantly lower FVC, FEV1, FEV1/FVC, and PEF (p < 0.001). Conclusions: Every day SHS exposure in children was associated with poorer lung function, higher BMI, and poorer physical fitness. Full article
(This article belongs to the Section Pediatric Pulmonary and Sleep Medicine)
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<p>Association between passive smoking exposure and BEEP test levels.</p>
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17 pages, 6889 KiB  
Article
Legionella in Primary School Hot Water Systems from Two Municipalities in the Danish Capital Region
by Niss Skov Nielsen, Peter Fojan, Rasmus Lund Jensen, Haseebullah Wahedi and Alireza Afshari
Microorganisms 2024, 12(10), 2074; https://doi.org/10.3390/microorganisms12102074 - 16 Oct 2024
Viewed by 282
Abstract
Legionella contamination in public water systems poses significant health risks, particularly in schools where vulnerable populations, including children, regularly use these facilities. This study investigates the presence of Legionella in the hot water systems from 49 primary schools across two municipalities in the [...] Read more.
Legionella contamination in public water systems poses significant health risks, particularly in schools where vulnerable populations, including children, regularly use these facilities. This study investigates the presence of Legionella in the hot water systems from 49 primary schools across two municipalities in the Danish capital region. Water samples were collected from taps in each school, and both first-flush and stabile temperature samples were analysed for Legionella contents. The findings revealed that 97% of schools in Municipality 1 and 100% in Municipality 2 had Legionella in their hot water systems. The content of Legionella colonies was significantly higher in schools in Municipality 1, which was probably because of overall lower water temperatures. At stabile temperatures, 76% and 50% of the schools in the two municipalities exceeded the European Union’s recommended limit of 1000 CFU/L. Stabile peripheral water temperatures were achieved after 3 min. Tap water temperatures above 54 °C and central tank temperatures above 59 °C were associated with Legionella contents below 1000 CFU/L. This study highlights the need for more stringent Legionella control procedures in schools, including higher water temperatures and refining Legionella reducing interventions with the addition of regular flow and draining procedures. Full article
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<p>Legionella colony counts (CFU/L) as a function of water temperature, both measured after 2 min of flow from peripheral taps of hot water systems from 49 schools in the two Danish municipalities. In this figure is included a vertical reference line that marks 50 degrees Celsius and a horizontal reference line that mark 10,000 CFU/L.</p>
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<p>Legionella colony counts (CFU/L) related to water temperature from samples taken from peripheral taps of hot water systems in 49 schools in the two Danish municipalities. The water samples were collected after 2 min of flow, and the temperatures were measured after 3 min of flow from peripheral taps. In this figure are included vertical reference lines that mark 50 degrees Celsius and 54 degree Celsius and horizontal reference lines that mark 1000 CFU/L and 10,000 CFU/L.</p>
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<p>Legionella colony counts (CFU/L) to water temperature measurements in the central hot water tank in 49 schools in the two Danish municipalities. After 2 min of hot water flow from peripheral taps, water samples for CFU measurements were collected. In this figure are included vertical reference lines that mark 59 degrees Celsius and horizontal reference lines that mark 1000 CFU/L and 10,000 CFU/L.</p>
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<p>Mean water temperature (in Celsius) from hot water systems at seven schools from two Danish municipalities. Water temperatures were measured from taps after 2, 3, 4, 5, and 8 min of flow.</p>
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<p>Mean and median contents of Legionella (CFU/L) from six schools from two Danish municipalities. Water samples were collected after 0, 2, 4, and 8 min. Standard error of mean around the mean line are marked by dots. The calculated mean CFU/L after 3 min of flow is marked on the mean line.</p>
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27 pages, 2215 KiB  
Article
From Welcoming Newly Arrived Migrant Students to Creating an Inclusive and Hospitable Environment: The Proposal from the Universe School
by Mar Badia Martín and Adriana Devant Cerezo
Educ. Sci. 2024, 14(10), 1122; https://doi.org/10.3390/educsci14101122 (registering DOI) - 16 Oct 2024
Viewed by 291
Abstract
In Catalan schools, the rising influx of newly immigrated students poses significant challenges concerning their inclusion. These students show lower academic performance and self-esteem, are more likely to engage in risky behaviors, and lack support as they cope with the mourning process of [...] Read more.
In Catalan schools, the rising influx of newly immigrated students poses significant challenges concerning their inclusion. These students show lower academic performance and self-esteem, are more likely to engage in risky behaviors, and lack support as they cope with the mourning process of migrating. Implementing intercultural education, working on socio-emotional skills, and helping to build a support network can be protective factors in improving the students’ development. This project was implemented in a Barcelona public school and aimed to identify the needs of newcomer students and enhance their inclusion. A questionnaire administered to 30 teachers revealed low knowledge about migratory mourning and intercultural education. Consequently, training sessions addressed to the school’s teaching staff were developed to provide them with the necessary knowledge and skills to deal with these topics. Interviews were conducted with the newly arrived children, specifically with 12 of them. They revealed a need for emotional support, the presence of migratory mourning, and a lack of a support network and socio-emotional skills. Students have appreciated the active listening and the opportunity to share their migration process. Teachers feel more empowered to support students in the migration mourning process after the training sessions. Feedback after the training sessions highlighted the clarity, ease of understanding, and usefulness of the material shared positively. The project lays the groundwork for more inclusive and intercultural initiatives in the school. Integrating the provided training into the teacher training curriculum could have a significant impact, better equipping educators to support recently arrived migrant students. Full article
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<p>Comparison of the issues that are currently taken into account and those that should be adopted in the school during the reception of newly arrived students.</p>
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<p>Emotions experienced by newly arrived students during the last year.</p>
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<p>Representation of the presence of migratory mourning domains collected in interviews with newly arrived students.</p>
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<p>Representation of the interpersonal relationships of the newly arrived students.</p>
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<p>This figure compares different perspectives: (<b>a</b>) Teachers’ difficulties in including newly arrived students in the classroom; (<b>b</b>) Difficulties for newcomers to feel included in the school.</p>
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<p>Resources from the Escola Univers that have helped newly arrived students during their reception process.</p>
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<p>Two-page extract from the teacher training in a visual format on migratory grief (<b>a</b>) and intercultural education (<b>b</b>).</p>
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22 pages, 349 KiB  
Article
Private Educational Expenditure Inequality between Migrant and Urban Households in China’s Cities
by Yiwen Chen, Ioana Salagean and Benteng Zou
Economies 2024, 12(10), 277; https://doi.org/10.3390/economies12100277 (registering DOI) - 15 Oct 2024
Viewed by 342
Abstract
This paper studies households’ expenditure on the education of children in China’s cities to assess how internal migrant families’ investment in the human capital of their offspring differs from that of local urban families. The private education-related expenditure reflects both households’ willingness to [...] Read more.
This paper studies households’ expenditure on the education of children in China’s cities to assess how internal migrant families’ investment in the human capital of their offspring differs from that of local urban families. The private education-related expenditure reflects both households’ willingness to invest in human capital and institutional constraints, as China’s household registration (hukou) system prevents children without a local city hukou from enrolling in urban public schools. In-school fees (consisting of statutory tuition and institutional tuition fees) are commonly topped-up with substantial private tutoring expenditure. We apply multiple regression to the 2008 “Rural–Urban Migration Survey in China” data to analyze the average expenditure differences between temporary migrants, permanent migrants and locals. The findings are, after controlling for social and economic characteristics, that: (1) the overall spending on education of migrant households overwhelmingly exceeds that of locals, which is expected since migrants must finance privately all education-related expenses their children incur; (2) migrant households spend more on institutional tuition fees compared to households with a local city hukou, reflecting the varying severity of administrative hurdles faced by families; and (3) temporary migrants spend more on institutional tuition fees than permanent migrant households, but less in private tutoring. Full article
(This article belongs to the Special Issue Economics of Migration)
39 pages, 3828 KiB  
Review
A Recent Advance in the Diagnosis, Treatment, and Vaccine Development for Human Schistosomiasis
by Tanushri Chatterji, Namrata Khanna, Saad Alghamdi, Tanya Bhagat, Nishant Gupta, Mohammad Othman Alkurbi, Manodeep Sen, Saeed Mardy Alghamdi, Ghazi A. Bamagous, Dipak Kumar Sahoo, Ashish Patel, Pankaj Kumar and Virendra Kumar Yadav
Trop. Med. Infect. Dis. 2024, 9(10), 243; https://doi.org/10.3390/tropicalmed9100243 (registering DOI) - 15 Oct 2024
Viewed by 908
Abstract
Schistosomiasis, which affects a large number of people worldwide, is among the most overlooked parasitic diseases. The disease is mainly prevalent in sub-Saharan Africa, southeast Asian countries, and South America due to the lack of adequate sanitation. The disease is mainly associated with [...] Read more.
Schistosomiasis, which affects a large number of people worldwide, is among the most overlooked parasitic diseases. The disease is mainly prevalent in sub-Saharan Africa, southeast Asian countries, and South America due to the lack of adequate sanitation. The disease is mainly associated with poor hygiene, sanitation, and contaminated water, so it is also known as a disease of poverty. Three Schistosoma species (S. mansoni, S. japonicum, and S. haematobium) cause significant human infections. Co-infections with Schistosoma and other parasites are widely common. All these parasites may cause intestinal or urogenital schistosomiasis, where the disease may be categorized into the acute, sensitized, and chronic phases. The disease is more prevalent among school children, which may cause anemia and reduce development. Chronic infections frequently cause significant liver, intestinal, and bladder damage. Women exposed to contaminated water while performing normal duties like washing clothes might acquire urogenital schistosomiasis (UGS), which can cause tissue damage and raise the risk of blood-borne disease transmission, including human immunodeficiency virus (HIV) transmission. Praziquantel (PZQ) is the World Health Organization (WHO)-prescribed treatment for individuals who are known to be infected, but it does not prevent further re-infections with larval worms. Vaccine development and new molecular-based diagnosis techniques have promised to be a reliable approach to the diagnosis and prevention of schistosomiasis. The current review emphasizes the recent advancement in the diagnosis of schistosomiasis by molecular techniques and the treatment of schistosomiasis by combined and alternative regimes of drugs. Moreover, this review has also focused on the recent outbreak of schistosomiasis, the development of vaccines, and their clinical trials. Full article
(This article belongs to the Section Neglected and Emerging Tropical Diseases)
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<p>(<b>a</b>) Schematic infection cycle of <span class="html-italic">schistosomiasis</span> in human hosts, (<b>b</b>) the life cycle of <span class="html-italic">S. japonicum</span> and intestinal schistosomiasis, and (<b>c</b>) the life cycle of <span class="html-italic">S. haematobium</span> and resulting genital schistosomiasis. (<b>a</b>) was produced with BioRender (<a href="http://www.biorender.com" target="_blank">www.biorender.com</a>; accessed on 8 January 2024).</p>
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<p>(<b>A</b>) The presented visual depicts a cystoscopic field of the posterior bladder mucosa exhibiting UGS lesions, granulomas, ulcers, and tumors. (<b>B</b>) Histology from the bladder mass biopsy shows <span class="html-italic">S. haematobium</span> ova (black circles) and Squamous cell carcinoma (SCC) of the bladder (expression of sialyl Lea). The figure is adapted with permission from Vale et al. (2015) and Santos et al. (2021) [<a href="#B37-tropicalmed-09-00243" class="html-bibr">37</a>,<a href="#B38-tropicalmed-09-00243" class="html-bibr">38</a>].</p>
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<p>The metabolites present in urine with urogenital schistosomiasis and UGS-associated SCC and absent from the urine samples of healthy individuals. The figure is adapted from Santos et al. (2021) [<a href="#B37-tropicalmed-09-00243" class="html-bibr">37</a>], Bruner et al. (2000) [<a href="#B39-tropicalmed-09-00243" class="html-bibr">39</a>], and Gouveia et al. (2020) with permission, along with license no: 5887131166730 [<a href="#B40-tropicalmed-09-00243" class="html-bibr">40</a>].</p>
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<p>Different phases of immune response in schistosomiasis.</p>
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<p>Global distribution of schistosomal infection adapted with permission from [<a href="#B51-tropicalmed-09-00243" class="html-bibr">51</a>].</p>
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<p><span class="html-italic">Schistosoma</span>-derived immunological diagnosis of human schistosomiasis.</p>
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<p>The current and upcoming POC diagnostic assays for schistosomiasis.</p>
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12 pages, 1005 KiB  
Article
Prevalence of Overweight and Obesity among Primary School Students in Split, Croatia
by Ivan Šimunović, Dina Mrčela, Željka Karin, Zenon Pogorelić and Joško Markić
Nutrients 2024, 16(20), 3488; https://doi.org/10.3390/nu16203488 (registering DOI) - 15 Oct 2024
Viewed by 543
Abstract
The rising prevalence of obesity among children and adolescents is a global public health concern, significantly contributing to noncommunicable chronic diseases such as cardiovascular disease, diabetes and cancer. In Croatia, obesity rates are alarmingly high, affecting both children and adults. Data from the [...] Read more.
The rising prevalence of obesity among children and adolescents is a global public health concern, significantly contributing to noncommunicable chronic diseases such as cardiovascular disease, diabetes and cancer. In Croatia, obesity rates are alarmingly high, affecting both children and adults. Data from the Institute of the Public Health of Split-Dalmatian County were analyzed to identify trends in body mass index (BMI) among primary school students in Split, Croatia and possible connection with sports participation and parental education levels. A longitudinal analysis of students was conducted across three medical examinations during primary school education. The findings showed an increase in the prevalence of overweight and obesity from 23.4% in the first to 30.2% in the fifth grade, returning back to 23.4% in the eighth grade. Significant differences among students were associated with parental education level. Boys who participated in sports demonstrated a higher BMI in the first grade but there was no difference in BMI in later grades. Sports participation had no significant impact on the BMI of girls. The study underscores the critical role of parental education in influencing children’s weight status and highlights the necessity of tailored public health interventions to address these trends from an early age. The implementation of comprehensive strategies, including educational programs and policy measures as part of the national health policy, is the only way to combat childhood obesity and promote long-term health benefits. Full article
(This article belongs to the Special Issue Dietary Surveys and Nutritional Epidemiology—2nd Edition)
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<p>Graphical representation of body mass categories based on the z-score of BMI (<span class="html-italic">n</span> = 427).</p>
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<p>Graphical representation of overweight and obesity prevalence based on sex difference (<span class="html-italic">n</span> = 427).</p>
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10 pages, 586 KiB  
Article
Media Usage and Adherence to the Mediterranean Diet in Children
by Alessandra Buja, Andrea Miatton, Anna Zanovello, Filippo Brocadello, Tatjana Baldovin, Marian Nur Muhiddin and Ilaria Spreghini
Nutrients 2024, 16(20), 3481; https://doi.org/10.3390/nu16203481 (registering DOI) - 14 Oct 2024
Viewed by 307
Abstract
Background: Increased screen time in children is significantly associated with lower adherence to the Mediterranean diet (MD). The purpose of this study was to explore the association between different types of media use and the adherence to the MD in children. Methods: The [...] Read more.
Background: Increased screen time in children is significantly associated with lower adherence to the Mediterranean diet (MD). The purpose of this study was to explore the association between different types of media use and the adherence to the MD in children. Methods: The study sample included 332 children aged 10–11 years attending the fifth year of primary school in Veneto, north-east Italy. The children’s mothers were surveyed on their children’s adherence to the MD, using the KidMed questionnaire, and on the time of media use, using the Media Activity Form-Parent (MAF-P). A multivariable backward stepwise linear regression was applied, adjusting the association for other potential confounding factors. Results: Children’s primary digital activities were watching TV or streaming platforms (5.0 h/week) and video content (2.5 h/week), followed by digital games (2.3 h/week). Lower adherence to the Mediterranean diet was associated with digital games (regression coefficient −0.65, SE 0.29, p = 0.026) and time spent watching TV or streaming platforms (regression coefficient −0.60, SE 0.29, p = 0.04). Conclusion: Interventions to promote healthier diets justify an approach that includes media education. Providing parents with recommendations on children’s use of digital media devices can empower them to improve their children’s well-being. Full article
(This article belongs to the Section Pediatric Nutrition)
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<p>The sample’s distribution of scores for media usage and time spent on online and digital activities.</p>
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21 pages, 2825 KiB  
Article
Executive Functioning in Different Types of Reading Disabilities
by Irene Cadime, Bruna Rodrigues, Iolanda Ribeiro and María Teresa Martín-Aragoneses
J. Intell. 2024, 12(10), 101; https://doi.org/10.3390/jintelligence12100101 - 14 Oct 2024
Viewed by 261
Abstract
Students with reading disabilities form a heterogeneous group: some struggle with accurate and fast reading (dysfluent readers), others with comprehension (poor comprehenders), and some face challenges in both areas (poor readers). Research has indicated a link between executive functioning skills and reading performance; [...] Read more.
Students with reading disabilities form a heterogeneous group: some struggle with accurate and fast reading (dysfluent readers), others with comprehension (poor comprehenders), and some face challenges in both areas (poor readers). Research has indicated a link between executive functioning skills and reading performance; yet, further studies are necessary to fully understand the executive profiles in various types of reading disabilities. The goal of this study was to examine differences in executive functioning among three types of reading disabilities, comparing their performance with that of children without difficulties in either skill (typical readers). Ninety-one students from schools in Portugal participated in the study. The results reveal specific deficits in naming speed and cognitive flexibility in poor readers and dysfluent readers compared to the other groups. Additionally, poor readers exhibited significantly slower processing speed and lower working memory. However, no significant differences were observed in planning. Discriminant function analysis results indicated that the examined executive functions are better at discriminating groups with fluency deficits than those with comprehension difficulties. In conclusion, these results suggest distinct deficit patterns in executive functioning skills across different types of reading disabilities. Taking into account these findings is crucial for effective assessment and intervention with these children. Full article
(This article belongs to the Special Issue Skill Acquisition, Expertise, and Achievement)
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<p>Mean differences among groups in the RAN and RAS tasks. Note: error bars represent 95% interval confidence. <span class="html-italic">p</span>-Values are for the Bonferroni post-hoc comparisons. Effect sizes: η<sup>2</sup><sub>p</sub> = 0.294 for RAS; η<sup>2</sup><sub>p</sub> = 0.236 for RAN.</p>
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<p>Mean differences among groups in the processing speed (symbol search) and working memory tasks. Note: error bars represent 95% interval confidence. <span class="html-italic">p</span>-Values are for the Bonferroni post-hoc comparisons. Effect sizes: η<sup>2</sup><sub>p</sub> = 0.085 for processing speed; η<sup>2</sup><sub>p</sub> = 0.115 for working memory.</p>
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<p>Mean differences among groups in the cognitive flexibility task. Note: error bars represent 95% interval confidence. <span class="html-italic">p</span>-values are for the Bonferroni post-hoc comparisons. Effect size: η<sup>2</sup><sub>p</sub> = 0.141.</p>
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<p>Plot of the readers groups’ centroids on the canonical discriminant functions.</p>
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16 pages, 260 KiB  
Article
Knowledge, Attitudes, and Practices towards Influenza Vaccine among Guangzhou Residents: A Cross-Sectional Study
by Jiawen Xu, Jianyun Lu, Qing He, Yu Ma, Keyi Wu, Haowen Chen, Xiaowei Ma and Xianbo Wu
Vaccines 2024, 12(10), 1169; https://doi.org/10.3390/vaccines12101169 - 14 Oct 2024
Viewed by 330
Abstract
Background: Influenza vaccination is an important prevention strategy for flu illness. However, the vaccination rate is still low in Guangzhou, China. This study aimed to understand the status of knowledge, the attitude towards the vaccines’ reliability and safety, and other aspects associated with [...] Read more.
Background: Influenza vaccination is an important prevention strategy for flu illness. However, the vaccination rate is still low in Guangzhou, China. This study aimed to understand the status of knowledge, the attitude towards the vaccines’ reliability and safety, and other aspects associated with the willingness and practice of influenza vaccines in the pediatric and adult populations of Guangzhou city. Methods: This study was performed in eleven districts in Guangzhou between November 2020 and December 2020, including the Yuexiu, Liwan, Haizhu, Tianhe, Baiyun, Panyu, Huadu, Nansha, Huangpu, Zengcheng, and Conghua districts. The parents of children and teenagers under the age of eighteen in Guangzhou were surveyed using self-administered questionnaires in four domains: demographic information, the knowledge status and perception of influenza vaccination, the willingness and attitude towards influenza vaccination, and previous vaccine uptake. A multivariable logistic regression was employed to assess the possible determinants of willingness and practice to receive influenza vaccination, calculating the odds ratios (ORs) and 95% confidence interval (CI). A two-sided p-value < 0.05 was deemed statistically significant. Results: A total of 13,213 valid questionnaires were collected (validity rate 98.8%). Out of these participants, 42.62% (5631 participants) expressed a willingness to receive the influenza vaccine, while 55.40% (7320 participants) reported that their children and teenagers had been vaccinated against the flu. Furthermore, 40.44% of the respondents (5343 participants) or other family members had received the influenza vaccine. Logistic regression indicated that factors such as being female (OR = 1.395, 95% CI: 1.278–1.522), being involved in the work of COVID-19 prevention and control (1.551, 1.396–1.724), affirming the preventive effects of vaccination (2.474, 2.106–2.906), knowing about annual influenza vaccination (2.756, 2.540–2.992), and understanding prioritized influenza vaccination populations (1.464, 1.343–1.596) were all positively associated with vaccination willingness. Conversely, middle-aged persons (aged 40–49 years old) (0.726, 0.617–0.853), higher educational levels (undergraduate versus middle school) (0.858, 0.768–0.959), heightened concerns about vaccine safety (considering side effects are obvious versus considering it is safe and basically no side effects) (0.284, 0.188–0.429) and lower knowledge scores (0.813, 0.701–0.942) were adversely linked with vaccination willingness. Conclusion: These findings provide essential insights for altering the perception of influence and influenza vaccination, as well as enhancing health communication strategies to improve influenza vaccine uptake among Guangzhou residents. Full article
(This article belongs to the Special Issue Immune Response after Respiratory Infection or Vaccination)
12 pages, 1160 KiB  
Article
Dehydration and Suboptimal Sleep Aggravate Early Renal Impairment in Children: Longitudinal Findings from the PROC Study
by Menglong Li, Huidi Xiao, Nubiya Amaerjiang, Bipin Thapa, Wen Shu, Yeerlin Asihaer, Mengying Guan, Sten H. Vermund, Zhiyong Zou, Dayong Huang and Yifei Hu
Nutrients 2024, 16(20), 3472; https://doi.org/10.3390/nu16203472 - 14 Oct 2024
Viewed by 462
Abstract
Background: While dehydration is associated with pediatric renal impairment, the regulation of hydration status can be affected by sleep. However, the interaction of hydration and sleep on kidney health remains unclear. Methods: We conducted a cohort study among 1914 healthy primary school children [...] Read more.
Background: While dehydration is associated with pediatric renal impairment, the regulation of hydration status can be affected by sleep. However, the interaction of hydration and sleep on kidney health remains unclear. Methods: We conducted a cohort study among 1914 healthy primary school children from October 2018 to November 2019 in Beijing, China. Four-wave urinary β2-microglobulin and microalbumin excretion were assayed to assess transient renal tubular and glomerular impairment, and specific gravity was measured to determine hydration status with contemporaneous assessment of sleep duration, other anthropometric, and lifestyle covariates. We used generalized linear mixed-effects models to assess longitudinal associations of sleep duration and hydration status with renal impairment. Results: We observed 1378 children with optimal sleep (9–<11 h/d, 72.0%), 472 with short sleep (<9 h/d), and 64 with long sleep (≥11 h/d, 3.3%). Over half (55.4%) of events determined across 6968 person-visits were transient dehydration, 19.4% were tubular, and 4.9% were glomerular impairment events. Taking optimal sleep + euhydration as the reference, the results of generalized linear mixed-effects models showed that children with long sleep + dehydration (odds ratio [OR]: 3.87 for tubular impairment [tubules] and 3.47 for glomerular impairment [glomerulus]), long sleep + euhydration (OR: 2.43 for tubules), optimal sleep + dehydration (OR: 2.35 for tubules and 3.00 for glomerulus), short sleep + dehydration (OR: 2.07 for tubules and 2.69 for glomerulus), or short sleep + euhydration (OR: 1.29 for tubules) were more likely to present transient renal impairment, adjusting for sex, age, body mass index z-score, systolic blood pressure z-score, screen time, physical activity, and Mediterranean diet adherence. Conclusions: Dehydration and suboptimal sleep aggravate transient renal impairment in children, suggesting its role in maintaining pediatric kidney health. Full article
(This article belongs to the Special Issue 2024 Collection: Dietary, Lifestyle and Children Health)
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<p>Median and prevalence of urinary indicators across four waves of this study by sleep duration. β<sub>2</sub>-MG: β<sub>2</sub>-microglobulin; MA: microalbumin; SG: specific gravity; IQR: interquartile range.</p>
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<p>Longitudinal associations between the interaction of sleep duration and hydration status with renal tubular and glomerular impairment among children aged 6–9 years in Beijing, China. Model 1: unadjusted; model 2: adjusted for sex, age, and body mass index z-score; model 3: model 2 further adjusted for systolic blood pressure z-score, screen time, physical activity level, and Mediterranean diet adherence. cOR: crude odds ratio; aOR: adjusted odds ratio; CI: confidence interval. All models included one random effect: the weekday of the urine assay.</p>
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14 pages, 212 KiB  
Article
Faith Inside an Immanent Frame
by Paul Sharkey
Religions 2024, 15(10), 1240; https://doi.org/10.3390/rel15101240 - 14 Oct 2024
Viewed by 291
Abstract
Those who are charged with the responsibility of governing, leading or teaching in Catholic schools at this time are challenged by questions which go to the heart of their school’s mission. How is it possible for the mission of the Catholic school to [...] Read more.
Those who are charged with the responsibility of governing, leading or teaching in Catholic schools at this time are challenged by questions which go to the heart of their school’s mission. How is it possible for the mission of the Catholic school to be realised in a culture that is increasingly secularising? What is the secularising context and how is religious belief still possible today? These are questions of profound significance also for the families who seek a Catholic education for their children. Charles Taylor’s analysis of our secular age provides a foundation for addressing these questions as do findings from the Enhancing Catholic School Identity (ECSI) research. Whilst the secularising context is sometimes painted as the enemy of Catholic education, it is presented here as being the context in which Catholic schools must realise their mission and this cultural context, like any cultural context, has elements which support the mission and elements which impede it. The following key concepts from Taylor’s analysis are reviewed because of their relevance for Catholic schools: the Expressivist Age, the Cross-Pressured context and the Immanent Frame. The Post-Critical Belief Scale from the ECSI research is also reviewed, as a key finding is that Post-Critical Belief is the only viable option for faith in a secularising context. Full article
15 pages, 947 KiB  
Article
Early Socio-Emotional Difficulty as a Childhood Barrier to the Expected Benefits of Active Play: Associated Risks for School Engagement in Adolescence
by Laurie-Anne Kosak, Kianoush Harandian, Simon L. Bacon, Isabelle Archambault, Luca Correale and Linda S. Pagani
Int. J. Environ. Res. Public Health 2024, 21(10), 1353; https://doi.org/10.3390/ijerph21101353 (registering DOI) - 13 Oct 2024
Viewed by 462
Abstract
Active play allows children to develop social and cognitive skills, which could lead to higher school engagement. Little is known about the role of child socioemotional difficulty in these associations. This study aims to examine the interaction between active play and socioemotional difficulty [...] Read more.
Active play allows children to develop social and cognitive skills, which could lead to higher school engagement. Little is known about the role of child socioemotional difficulty in these associations. This study aims to examine the interaction between active play and socioemotional difficulty in childhood and their prospective association with academic engagement in adolescence. The participants were 4537 children (51.1% boys) who were longitudinally followed, between ages 6 and 14 years, from the National Longitudinal Study on Children and Youth (NLSCY), Canada. Active play (weekly organized sport and unstructured physical activity outside of school hours) and child behavior (hyperactivity, anxiety, and relational difficulties) were reported by mothers for their children at age 6 years. Academic engagement was self-reported at age 14 years. Unstructured physical activity predicted lower subsequent school engagement for boys (β = −0.057, p < 0.05). Boys with high anxiety symptoms and high relational aggression who participated in more unstructured physical activity in childhood were subsequently less engaged in school (respectively, β = −0.066, p < 0.05 and β = −0.062, p < 0.05). Girls who partook in more organized sports showed lower school engagement in adolescence when they had high anxiety symptoms (β = −0.067, p < 0.05). Although past studies have highlighted the contribution of active play to school engagement, certain socioemotional difficulties could impede the child’s ability to reap its benefits. Full article
(This article belongs to the Special Issue Mental Health and Wellbeing of Children and Adolescents)
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<p>Decomposition of the adjusted interaction between anxiety symptoms and organized sports at age 6 years associated with school engagement at age 14 years for girls.</p>
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<p>Decomposition of the adjusted interaction between anxiety symptoms and unstructured physical activity at age 6 years associated with school engagement at age 14 years for boys.</p>
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<p>Decomposition of the adjusted interaction between relational aggression and unstructured physical activity at age 6 years associated with school engagement at age 14 years for boys.</p>
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11 pages, 249 KiB  
Article
Teacher Comfort in Managing Asthma: A Two-State Study
by Yvette Q. Getch, Ethan Schilling, Stacey M. Neuharth-Pritchett and Sofia Hirt
Allergies 2024, 4(4), 181-191; https://doi.org/10.3390/allergies4040013 - 12 Oct 2024
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Abstract
Background/Objectives: This study assessed teacher comfort in supporting the medical management of children with asthma in elementary and middle schools in two southern states in the U.S. Teacher comfort in asthma management is a largely underexplored area yet holds promise to support medical [...] Read more.
Background/Objectives: This study assessed teacher comfort in supporting the medical management of children with asthma in elementary and middle schools in two southern states in the U.S. Teacher comfort in asthma management is a largely underexplored area yet holds promise to support medical management in schools. Methods: Using survey methods, data were gathered from a random sample of teachers in two southern U.S. states (n = 574). Data from the Teacher Capability and School Resource Scale for Asthma Management scale were used to assess teacher comfort and capability in managing stressful asthma management episodes. Results: Teachers expressed comfort in supporting children with asthma in their classrooms. On the Teacher Capability in Social and Emotional Aspects of Asthma Management (SEAM) factor, the mean rating was 3.89 (SD = 0.83) out of 5, and the mean rating for the School Resources/Institutional Capability for Asthma Management factor was 3.77 (SD = 0.99) out of 5. Conclusions: The findings demonstrate that access to school, community, and medical resources; coordinated school-based asthma care plans; and pre-service preparation improve teacher comfort. School nursing support is needed for teacher education. Full article
(This article belongs to the Section Asthma/Respiratory)
12 pages, 514 KiB  
Article
Impact of Weight Status on Hemodynamic Parameters and Aerobic Fitness in School-Aged Children: A Study in a Rural School Community
by Ncomi Primrose Lukhele, Lourens Millard and Gerrit Jan Breukelman
Int. J. Environ. Res. Public Health 2024, 21(10), 1340; https://doi.org/10.3390/ijerph21101340 - 10 Oct 2024
Viewed by 359
Abstract
Maintaining a high level of physical activity provides significant health benefits for children, particularly in enhancing cardiorespiratory fitness and maintaining a healthy weight. This study aimed to investigate the impact of weight status on children’s hemodynamic parameters and aerobic fitness levels. This cross-sectional [...] Read more.
Maintaining a high level of physical activity provides significant health benefits for children, particularly in enhancing cardiorespiratory fitness and maintaining a healthy weight. This study aimed to investigate the impact of weight status on children’s hemodynamic parameters and aerobic fitness levels. This cross-sectional study included 350 rural primary school children (146 boys and 204 girls) aged 11–13 years, randomly selected from two schools in the King Cetshwayo District, KwaDlangezwa area of KwaZulu-Natal. The anthropometric measurements recorded included height, weight, waist circumference, and hip circumference, with percentiles calculated using Cole’s Lambda, Mu, and Sigma method. Additionally, skinfold measurements were obtained at four sites (biceps, triceps, subscapular, and suprailiac). Hemodynamic measurements included systolic blood pressure, diastolic blood pressure, and heart rate. Aerobic fitness was assessed using the 20 m shuttle run test, which evaluated speed, level, and age. The healthy group demonstrated significantly lower ratios in several measurements compared to those of the overweight group, i.e., the VO2max was 6% higher (<0.001), the waist-to-hip ratio was 6% lower (<0.001), the body fat percentage was 16% lower (<0.001), the waist circumference was 12% lower (<0.001), and the resting heart rate was 3% lower (p ≤ 0.055). Differences in systolic and diastolic blood pressure were also observed, with the systolic pressure 2% lower (p ≤ 0.116) and the diastolic pressure 3% lower (p ≤ 0.086) in the healthy group. The study revealed a significant association between body weight status, aerobic fitness, and blood pressure parameters. Conducted in rural primary schools in KwaDlangezwa, KwaZulu-Natal, the research highlights notable correlations among weight status, aerobic competence, and blood pressure (BP) in children aged 11 to 13 years. The findings indicate that children with a healthy body weight showed higher VO2max levels and a reduced risk of developing childhood obesity and hypertension, unlike their overweight or obese peers, who displayed lower aerobic fitness and higher blood pressure. Full article
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<p>Procedures of the study.</p>
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16 pages, 2933 KiB  
Article
Dynamics of Peripheral Lymphocyte Subsets from Birth until Old Age
by Nawal A. B. Taher, Johana M. Isaza-Correa, Ashanty M. Melo, Lynne A. Kelly, Alhanouf I. Al-Harbi, Mary I. O’Dea, Zunera Zareen, Emer Ryan, Murwan Omer, Liam Townsend, Eleanor J. Molloy and Derek G. Doherty
Immuno 2024, 4(4), 358-373; https://doi.org/10.3390/immuno4040023 - 10 Oct 2024
Viewed by 381
Abstract
The immune system is inexperienced before birth and tends to be tolerogenic, rather than immunogenic. After birth, the adaptive immune system develops while facing microbial challenges, but it can become impaired as old age progresses and persistent inflammation can lead to chronic morbidity, [...] Read more.
The immune system is inexperienced before birth and tends to be tolerogenic, rather than immunogenic. After birth, the adaptive immune system develops while facing microbial challenges, but it can become impaired as old age progresses and persistent inflammation can lead to chronic morbidity, disability and frailty. To investigate the potential contributions of lymphocyte subsets to immunity from birth until old age, we enumerated circulating innate and conventional lymphocytes and measured serum cytokine levels in 10 cord blood samples and in peripheral blood from 10 healthy term neonates, 23 healthy school-age children, 25 young adults and 11 older subjects. Flow cytometric analysis revealed that B cell frequencies increase during childhood and gradually decrease into adulthood, whereas natural killer cell frequencies increase throughout life. T cell frequencies remained relatively constant throughout life, as did their expression of CD4 and CD8. However, all four innate T cell populations studied—invariant natural killer T cells, mucosa-associated invariant T cells and the Vδ1 and the Vδ2 subsets of γδ T cells—were extremely rare in cord blood and in peripheral blood of neonates, but they expanded after birth reaching highest levels in adulthood. Analysis of serum cytokine levels revealed that proinflammatory and T helper type 1 (Th1) cytokine levels increase in adulthood, whereas Th2 and Th17 cytokine levels remain relatively constant. These changes in lymphocyte numbers and cytokine levels across the lifetime are likely to affect immunocompetence, leaving newborn and elderly people susceptible to infection, cancer and immune-mediated disease. Full article
(This article belongs to the Section Acquired Immunity)
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<p>Gating strategy for the detection of T cells, B cells, NK cells, CD4<sup>+</sup> T cells, CD8<sup>+</sup> T cells, CD4<sup>-</sup>CD8<sup>-</sup> T cells, CD4<sup>+</sup>CD8<sup>+</sup> T cells, iNKT cells, MAIT cells, Vδ1 T cells and Vδ2 T cells by flow cytometry. Whole blood was stained with a dead cell stain (DCS) and monoclonal antibodies specific for glycophorin A, CD3, CD4, CD8, CD19, CD56, CD161 and the Vα7.2, Vα24Jα18, Vδ1 and Vδ2 T cell receptors and analysed by flow cytometry. Upper panels, left to right: flow cytometry dot plots showing forward scatter area (FSC-A) plotted against side scatter area (SSC-A) with an electronic gate drawn around the lymphocytes; dot plot showing CD3 plotted against glycophorin A with a gate drawn around the glycophorin-negative cells to exclude erythrocytes; dot plot showing FSC-A plotted against FSC-height (FSC-H) for gated lymphocytes with a gate drawn around the single cells; dot plot showing FSC-A plotted against the dead cell stain for gated single cells with a gate drawn around the live cells. Centre panels: five dot plots showing expression of CD3 and either CD19, CD56, Vα24Jα18, Vδ1 or Vδ2 by gated live singlet lymphocytes with gates drawn around the B cells, T cells, NK cells, iNKT cells, Vδ1 and Vδ2 T cells. Lower panels, left and right: dot plot showing expression of CD4 and CD8 by gated T cells with gates drawn around the CD4<sup>+</sup> T cells, CD8<sup>+</sup> T cells, double negative (DN) CD4<sup>-</sup>CD8<sup>-</sup> T cells and double positive (DP) CD4<sup>+</sup>CD8<sup>+</sup> T cells; dot plot showing expression of CD161 and Vα7.2 by gated T cells with a gate drawn around the MAIT cells.</p>
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<p>T cell (<b>A</b>), B cell (<b>B</b>) and NK cell (<b>C</b>) frequencies in cord blood (n = 10) and in peripheral blood of neonates (n = 17), school-age children (n = 23), young adults (n = 25) and elderly adults (n = 11). Cell frequencies in the different groups were compared using the Kruskal–Wallis test with Dunn’s multiple comparison analysis.</p>
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<p>Frequencies of CD4<sup>+</sup> (<b>A</b>), CD8<sup>+</sup> (<b>B</b>), CD4<sup>+</sup>CD8<sup>+</sup> (double positive or DP; (<b>C</b>)) and CD4<sup>-</sup>CD8<sup>-</sup> (double negative or DN; (<b>D</b>)) T cells in cord blood (n = 10) and in peripheral blood of neonates (n = 17), school-age children (n = 23), young adults (n = 25) and elderly adults (n = 11). Cell frequencies in the different groups were compared using the Kruskal–Wallis test with Dunn’s multiple comparison analysis.</p>
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<p>Frequencies of the innate T cells—Vδ1 T cells (<b>A</b>), Vδ2 T cells (<b>B</b>), invariant natural killer T (iNKT) cells (<b>C</b>) and mucosal-associated invariant T (MAIT) cells (<b>D</b>)—in cord blood (n = 10) and in peripheral blood of neonates (n = 17), school-age children (n = 23), young adults (n = 25) and elderly adults (n = 11). Cell frequencies in the different groups were compared using the Kruskal–Wallis test with Dunn’s multiple comparison analysis.</p>
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<p>Frequencies of CD8<sup>+</sup> (<b>A</b>), CD4<sup>-</sup> CD8<sup>-</sup> (<b>B</b>) and activated (CD69<sup>+</sup>; (<b>C</b>)) MAIT cells in cord blood (n = 10) and in peripheral blood of neonates (n = 17), school-age children (n = 23), young adults (n = 25) and elderly adults (n = 11). Cell frequencies in the different groups were compared using the Kruskal–Wallis test with Dunn’s multiple comparison analysis.</p>
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<p>Cytokine levels in 10 cord blood samples and in peripheral blood from 10 healthy neonates, 10 school-age children and 15 adults. Cytokine levels in the different groups were compared using the Kruskal–Wallis test with Dunn’s multiple comparison analysis.</p>
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