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Search Results (1,880)

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27 pages, 18578 KiB  
Article
Development of Construction Safety Dashboard Based on Four-Dimensional Building Information Modeling for Fall Prevention: Case Study of Stadium Roof Works
by Rossy Armyn Machfudiyanto, Titi Sari Nurul Rachmawati, Naufal Budi Laksono, Mehrtash Soltani and Chansik Park
Buildings 2024, 14(9), 2882; https://doi.org/10.3390/buildings14092882 - 12 Sep 2024
Viewed by 243
Abstract
The construction sector is known for exposing workers to numerous potential hazards, with falls from heights being the leading cause. These fatal fall accidents not only result in human loss but also impose significant financial costs on construction projects. However, current safety planning [...] Read more.
The construction sector is known for exposing workers to numerous potential hazards, with falls from heights being the leading cause. These fatal fall accidents not only result in human loss but also impose significant financial costs on construction projects. However, current safety planning and management is typically carried out manually using safety documents and 2D models, which are time-consuming and labor-intensive. There is also a lack of visualization for the placement of temporary safety facilities (TSFs) during construction. Meanwhile, Building Information Modeling (BIM) has the potential to be used as a comprehensive workspace planning for TSFs in a scheduling manner. Therefore, this study proposes the development of a construction safety dashboard to inform workers about fall hazards using spatial–temporal data stored in 4D BIM. The proposed approach includes four modules: (1) identification and assessment of risk from identified work activities, (2) development of 4D BIM model, (3) creation of a dashboard to share safety knowledge, and (4) validation of the dashboard through interviews with safety managers and site workers. This approach is tested on a stadium project, particularly focusing on roof work activities, where workers are most prone to fall hazards. The proposed method aims to provide ease for site workers to access safety knowledge, including risk identification (including risk, fatality, location, and time), visualization of TSFs, personal protective equipment, and safety work instructions. This interactive dashboard also enables safety managers to plan safety measures, allocate TSFs efficiently, and make well-informed decisions to effectively mitigate risks. Full article
(This article belongs to the Section Construction Management, and Computers & Digitization)
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<p>Framework for construction safety dashboard development.</p>
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<p>Workflow of HIRARC analysis.</p>
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<p>The content of the dashboard: (<b>a</b>) front page; (<b>b</b>) safety knowledge page of chosen work activity.</p>
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<p>Safety knowledge content: (<b>a</b>) temporary safety facilities; (<b>b</b>) risk identification.</p>
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<p>Roof zones of stadium project: (<b>a</b>) Zone 1; (<b>b</b>) Zone 2; (<b>c</b>) Zone 3; (<b>d</b>) Zone 4.</p>
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<p>WBS of roof work stadium construction project.</p>
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<p>Work activities of roof work stadium construction project.</p>
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<p>The page to select the work progress phase in the dashboard.</p>
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<p>The page of work progress phase for console mounting activity: (<b>a</b>) Phase 1; (<b>b</b>) Phase 2.</p>
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<p>The safety knowledge tabs of the dashboard for console mounting activity: (<b>a</b>) identified risk; (<b>b</b>) temporary safety facility; (<b>c</b>) PPE; (<b>d</b>) safety work instructions.</p>
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<p>The dashboard for space frame roof assembly: (<b>a</b>) Phase 1; (<b>b</b>) Phase 2.</p>
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<p>The safety knowledge tabs of the dashboard for space frame roof assembly: (<b>a</b>) identified risk; (<b>b</b>) temporary safety facility; (<b>c</b>) PPE; (<b>d</b>) safety work instructions.</p>
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13 pages, 2122 KiB  
Article
Prevalence of Septate Uterus in a Large Population of Women of Reproductive Age: Comparison of ASRM 2016 and 2021, ESHRE/ESGE, and CUME Diagnostic Criteria: A Prospective Study
by Isabel Carriles, Isabel Brotons, Tania Errasti, Alvaro Ruiz-Zambrana, Artur Ludwin and Juan Luis Alcazar
Diagnostics 2024, 14(18), 2019; https://doi.org/10.3390/diagnostics14182019 - 12 Sep 2024
Viewed by 228
Abstract
In this study, we aimed to assess and compare the prevalence of septate uterus using the diagnostic criteria of the ESHRE-ESGE, ASRM 2016, ASRM 2021, and CUME classifications. This prospective observational study included 977 women of reproductive age. Each participant underwent a transvaginal [...] Read more.
In this study, we aimed to assess and compare the prevalence of septate uterus using the diagnostic criteria of the ESHRE-ESGE, ASRM 2016, ASRM 2021, and CUME classifications. This prospective observational study included 977 women of reproductive age. Each participant underwent a transvaginal ultrasound, and a 3D volume of the uterus was obtained for further analysis. Offline assessment of the uterine coronal plane was conducted to measure uterine wall thickness, fundal indentation length, and indentation angle. The diagnosis of a septate uterus was determined according to the criteria of the ESHRE-ESGE, ASRM, and CUME classifications. The prevalence of septate uterus was then calculated and compared across these classifications. The ESHRE-ESGE classification identified 132 women (13.5%) with a septate uterus. The 2016 ASRM classification identified nine women (0.9%), with an additional nine women falling into a grey zone. The 2021 ASRM classification identified fourteen women (1.4%), with eleven women in the grey zone. The CUME classification identified 23 women (2.4%). The prevalence of septate uterus was significantly higher when using the ESHRE-ESGE criteria compared to the 2016 ASRM [relative risk (RR): 7.33 (95% CI: 4.52–11.90)], the 2021 ASRM [RR: 5.28 (95% CI: 3.47–8.02)], and the CUME [RR: 5.94 (95% CI: 3.72–8.86)] (p < 0.001). Our findings indicate that the ESHRE-ESGE criteria result in a significantly higher prevalence of septate uterus compared to the ASRM and CUME criteria. The ASRM 2016 criteria may underdiagnose more than half of the cases. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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<p>Three-dimensional ultrasound depicting how measurements were taken, according to Ludwin and Martin’s recommendations [<a href="#B23-diagnostics-14-02019" class="html-bibr">23</a>].</p>
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<p>A case of septate uterus according to ESHRE-ESGE criteria. I:WT ratio is 192%.</p>
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<p>The same case as <a href="#diagnostics-14-02019-f002" class="html-fig">Figure 2</a>. According to 2016 and 2021 ASRM criteria, this is a case that falls within the grey zone. Indentation length is 17.3 mm, but indentation angle is 104° (larger than 90°).</p>
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<p>The same case as <a href="#diagnostics-14-02019-f002" class="html-fig">Figure 2</a> and <a href="#diagnostics-14-02019-f003" class="html-fig">Figure 3</a>. According to CUME criteria, this is a septate uterus, with an indentation length of 17.3 mm.</p>
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<p>(<b>A</b>) Box plot showing median fundal indentation length, interquartile range, and outliers. (<b>B</b>) Box plot showing median indentation angle, interquartile range, and outliers. (<b>C</b>) Box plot showing median uterine wall thickness, interquartile range, and outliers. (<b>D</b>) Box plot showing median uterine wall thickness–indentation ratio (UWT:I), interquartile range, and outliers.</p>
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<p>(<b>A</b>) Box plot showing median fundal indentation length, interquartile range, and outliers. (<b>B</b>) Box plot showing median indentation angle, interquartile range, and outliers. (<b>C</b>) Box plot showing median uterine wall thickness, interquartile range, and outliers. (<b>D</b>) Box plot showing median uterine wall thickness–indentation ratio (UWT:I), interquartile range, and outliers.</p>
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<p>(<b>A</b>) Box plot showing median fundal indentation length, interquartile range, and outliers. (<b>B</b>) Box plot showing median indentation angle, interquartile range, and outliers. (<b>C</b>) Box plot showing median uterine wall thickness, interquartile range, and outliers. (<b>D</b>) Box plot showing median uterine wall thickness–indentation ratio (UWT:I), interquartile range, and outliers.</p>
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26 pages, 2478 KiB  
Review
An Evaluation of the Technologies Used for the Real-Time Monitoring of the Risk of Falling from Height in Construction—Systematic Review
by Filipa Pereira, María de las Nieves González García and João Poças Martins
Buildings 2024, 14(9), 2879; https://doi.org/10.3390/buildings14092879 - 12 Sep 2024
Viewed by 256
Abstract
The construction industry has the highest number of fatal accidents compared to other industries. However, manual safety compliance monitoring is complex and difficult for safety engineers, and more automated solutions need to be found. The main research objective was to review the state [...] Read more.
The construction industry has the highest number of fatal accidents compared to other industries. However, manual safety compliance monitoring is complex and difficult for safety engineers, and more automated solutions need to be found. The main research objective was to review the state of the art of real-time monitoring technologies used to assess the risk of falling from height in the construction sector. A systematic review is proposed in order to summarise the technologies used for real-time monitoring in the construction sector, following the PRISMA methodology. Only studies that assessed the risk of falling in real time were selected. From an initial set of 1289 articles, 40 were classified as strictly relevant to addressing the research questions. Various technologies that use artificial intelligence have been designed to monitor workers in real time and to send alerts to workers at any time in the event of a risk situation, thus preventing accidents. This study showed that new technologies are being introduced to predict the risk of a fall in real time, changing the approach from reactive to proactive and allowing this monitoring to improve workplace surveillance and safety. Further research is needed to develop effective systems that are easy for people to use without compromising productivity. Full article
(This article belongs to the Section Construction Management, and Computers & Digitization)
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<p>PRISMA diagram [<a href="#B22-buildings-14-02879" class="html-bibr">22</a>,<a href="#B23-buildings-14-02879" class="html-bibr">23</a>] of the systematic review conducted for this study.</p>
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<p>Number of relevant publications per year.</p>
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<p>Number of publications per country.</p>
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<p>Citation–sources network of the representative journals.</p>
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<p>Keyword co-occurrence networks of technologies used for real-time monitoring research.</p>
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18 pages, 1415 KiB  
Article
Optimizing Fall Risk Diagnosis in Older Adults Using a Bayesian Classifier and Simulated Annealing
by Enrique Hernandez-Laredo, Ángel Gabriel Estévez-Pedraza, Laura Mercedes Santiago-Fuentes and Lorena Parra-Rodríguez
Bioengineering 2024, 11(9), 908; https://doi.org/10.3390/bioengineering11090908 - 11 Sep 2024
Viewed by 285
Abstract
The aim of this study was to improve the diagnostic ability of fall risk classifiers using a Bayesian approach and the Simulated Annealing (SA) algorithm. A total of 47 features from 181 records (40 Center of Pressure (CoP) indices and 7 patient descriptive [...] Read more.
The aim of this study was to improve the diagnostic ability of fall risk classifiers using a Bayesian approach and the Simulated Annealing (SA) algorithm. A total of 47 features from 181 records (40 Center of Pressure (CoP) indices and 7 patient descriptive variables) were analyzed. The wrapper method of feature selection using the SA algorithm was applied to optimize the cost function based on the difference of the mean minus the standard deviation of the Area Under the Curve (AUC) of the fall risk classifiers across multiple dimensions. A stratified 60–20–20% hold-out method was used for train, test, and validation sets, respectively. The results showed that although the highest performance was observed with 31 features (0.815 ± 0.110), lower variability and higher explainability were achieved with only 15 features (0.780 ± 0.055). These findings suggest that the SA algorithm is a valuable tool for feature selection for acceptable fall risk diagnosis. This method offers an alternative or complementary resource in situations where clinical tools are difficult to apply. Full article
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<p>Absolute frequencies of the features selected by SA through all dimensions (<math display="inline"><semantics> <mrow> <mi>n</mi> </mrow> </semantics></math> = 11 to 35). The colors refer to a gradient bar associated with the frequency of use of the features.</p>
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<p>Set of features that integrate the best-performance results in feature selection.</p>
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<p>Performance of the SA algorithm based on the AUC value with respect to the dimension size.</p>
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27 pages, 4364 KiB  
Article
Investigating Factors Influencing Crash Severity on Mountainous Two-Lane Roads: Machine Learning Versus Statistical Models
by Ziyuan Qi, Jingmeng Yao, Xuan Zou, Kairui Pu, Wenwen Qin and Wu Li
Sustainability 2024, 16(18), 7903; https://doi.org/10.3390/su16187903 - 10 Sep 2024
Viewed by 415
Abstract
Due to poor road design, challenging terrain, and difficult geological conditions, traffic accidents on mountainous two-lane roads are more frequent and severe. This study aims to address the lack of understanding of key factors affecting accident severity with the goal of improving mountainous [...] Read more.
Due to poor road design, challenging terrain, and difficult geological conditions, traffic accidents on mountainous two-lane roads are more frequent and severe. This study aims to address the lack of understanding of key factors affecting accident severity with the goal of improving mountainous traffic safety, thereby contributing to sustainable transportation systems. The focus of this study is to compare the interpretability of model performances with three statistical models (Ordered Logit, Partial Proportional Odds Model, and Multinomial Logit) and six machine learning models (Decision Tree, Random Forest, Gradient Boosting, Extra Trees, AdaBoost, and XGBoost) on two-lane mountain roads in Yunnan Province, China. Additionally, we assessed the ability of these models to uncover underlying causal relationships, particularly how accident causes affect severity. Using the SHapley Additive exPlanations (SHAP) method, we interpreted the influence of risk factors in the machine learning models. Our findings indicate that machine learning models, especially XGBoost, outperform statistical models in predicting accident severity. The results highlight that accident patterns are the most significant determinants of severity, followed by road-related factors and the type of colliding vehicles. Environmental factors like weather, however, have minimal impact. Notably, vehicle falling, head-on collisions, and longitudinal slope sections are linked to more severe accidents, while minor accidents are more frequent on horizontal curve sections and areas that combine curves and slopes. These insights can help traffic management agencies develop targeted measures to reduce accident rates and enhance road safety, which is critical for promoting sustainable transportation in mountainous regions. Full article
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<p>The workflow of the research framework.</p>
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<p>Changes in AIC and BIC values during iteration.</p>
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<p>Comparison of AIC and BIC values in statistical models.</p>
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<p>Accuracy comparison by resampling methods.</p>
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<p>Comparison of F1-score in machine learning models.</p>
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<p>ROC curves of multiple models for different accident severity levels. Note: WR (weather), AP (accident pattern), RSC (roadside conditions), CVT (collision vehicle type), TE (time), RA (road alignment), VCT (vertical curve type), and HY (holiday).</p>
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<p>Horizontal comparison of model fitting abilities.</p>
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<p>SHAP summary plot. Note: WR (weather), AP (accident pattern), RSC (roadside conditions), CVT (collision vehicle type), TE (time), RA (road alignment), VCT (vertical curve type), and HY (holiday).</p>
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<p>SHAP dependence plots for AP across different accident severities. Note: on the horizontal axis, AP refers to the accident pattern; 0 represents collision with fixed object; 1 represents rollover; 2 represents vehicle falling; 3 represents side collision; 4 represents rear-end collision; 5 represents head-on collision; 6 represents collision with pedestrian; 7 represents other collisions; 8 represents scratch.</p>
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<p>SHAP dependence plots for CVT across different accident severities. Note: on the horizontal axis, CVT refers to the collision vehicle type. A value of 0 represents vehicle pedestrian accident; 1 represents single vehicle accident; 2 represents multiple vehicle accident.</p>
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<p>SHAP dependence plots for RA across different accident severities. Note: on the horizontal axis, RA refers to the road alignment. A value of 0 represents horizontal curve section; 1 represents longitudinal slope section; 2 represents straight road section; 3 represents combination of curved and sloping sections.</p>
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24 pages, 4050 KiB  
Article
Sources, Distribution, and Health Implications of Heavy Metals in Street Dust across Industrial, Capital City, and Peri-Urban Areas of Bangladesh
by Md. Sohel Rana, Qingyue Wang, Weiqian Wang, Christian Ebere Enyoh, Md. Rezwanul Islam, Yugo Isobe and Md Humayun Kabir
Atmosphere 2024, 15(9), 1088; https://doi.org/10.3390/atmos15091088 - 7 Sep 2024
Viewed by 638
Abstract
Heavy metals in road dusts can directly pose significant health risks through ingestion, inhalation, and dermal contact. This study investigated the pollution, distribution, and health effect of heavy metals in street dust from industrial, capital city, and peri-urban areas of Bangladesh. Inductively coupled [...] Read more.
Heavy metals in road dusts can directly pose significant health risks through ingestion, inhalation, and dermal contact. This study investigated the pollution, distribution, and health effect of heavy metals in street dust from industrial, capital city, and peri-urban areas of Bangladesh. Inductively coupled plasma mass spectrometry (ICP-MS) examined eight hazardous heavy metals such as Zn, Cu, Pb, Ni, Mn, Cr, Cd, and Co. Results revealed that industrial areas showed the highest metal concentrations, following the order Mn > Zn > Cr > Pb > Ni > Co > Cd, with an average level of 444.35, 299.25, 238.31, 54.22, 52.78, 45.66, and 2.73 mg/kg, respectively, for fine particles (≤20 μm). Conversely, multivariate statistical analyses were conducted to assess pollution levels and sources. Anthropogenic activities like traffic emissions, construction, and industrial processing were the main pollution sources. A pollution load index revealed that industrial areas had significantly higher pollution (PLI of 2.45), while the capital city and peri-urban areas experienced moderate pollution (PLI of 1.54 and 1.59). Hazard index values were below the safety level of 1, but health risk evaluations revealed increased non-carcinogenic risks for children, especially from Cr, Ni, Cd, and Pb where Cr poses the highest cancer risk via inhalation, with values reaching 1.13 × 10−4–5.96 × 10−4 falling within the threshold level (10−4 to 10−6). These results underline the need for continuous environmental monitoring and pollution control in order to lower health hazards. Full article
(This article belongs to the Special Issue Climate Change, Allergy and Respiratory Diseases)
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<p>(<b>a</b>) A map of street dust sampling areas in Bangladesh, (<b>b</b>) showing the Mymensingh Division, with sampling locations highlighted along the street, and (<b>c</b>) showing the Dhaka division, highlighting sampling locations from the street.</p>
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<p>Street dust sampling and preparation stage.</p>
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<p>Street dust sample preparation and heavy metal analysis.</p>
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<p>Plots of principal components in rotated space for toxic elements in suspended street dust.</p>
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<p>An HCA dendrogram illustrating the categorization of toxic elements in street dust being studied.</p>
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<p>Igeo value of toxic elements in three different areas. (IA indicates ‘industrial area’, CCA indicates ‘capital city area’, and PUA indicates ‘peri-urban area’).</p>
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14 pages, 786 KiB  
Article
Examining Performance between Different Cognitive-Motor Dual-Task Tests in Community-Dwelling Older Adults
by Anastasios Georgantas, Panagiota Stefani, Epameinondas Lyros, Dimitrios Chytas and Anna Christakou
Appl. Sci. 2024, 14(17), 7957; https://doi.org/10.3390/app14177957 - 6 Sep 2024
Viewed by 336
Abstract
Performing dual-task (DT) activities is essential for independent living among elderly people. No study has investigated motor performance in various cognitive-motor DT activities, utilizing the Timed Up and Go (TUG) test. This study aimed to compare motor performance between four cognitive-motor DT tests [...] Read more.
Performing dual-task (DT) activities is essential for independent living among elderly people. No study has investigated motor performance in various cognitive-motor DT activities, utilizing the Timed Up and Go (TUG) test. This study aimed to compare motor performance between four cognitive-motor DT tests in community-dwelling older adults. The sample consisted of 60 older women. The cognitive tasks performed with the TUG test were (a) mental calculation, (b) memory recall, (c) verbal fluency, and (d) reaction to a stimulus. Lower limb muscle strength was assessed with the 30-Second Chair Stand Test, balance with the Four Square Step Test, and balance confidence with the Activities-specific Balance Confidence Scale. Completion times and DT costs were calculated. Mental calculation (r = 0.63, p < 0.01) and verbal fluency (r = 0.65, p < 0.01) tasks were similarly correlated with the TUG test, and significantly impacted motor performance compared to other DT tests. The reaction to a stimulus test showed a high relationship with the TUG test (r = 0.89, p < 0.01) and had the least impact on motor performance. These findings suggest that the cognitive task type can significantly influence motor performance during DT activities. Adding a cognitive load to the TUG test may improve its ability to identify older adults at risk for falls, aiding in the development of targeted interventions. Further research is required to validate these findings. Full article
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<p>Relationships between Timed Up and Go (TUG) test performance and (<b>a</b>) TUG<sub>ME</sub>, (<b>b</b>) TUG<sub>MC</sub>, (<b>c</b>) TUG<sub>VF</sub> and (<b>d</b>) TUG<sub>RE</sub> performance.</p>
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<p>Relationships between Timed Up and Go (TUG) test performance and (<b>a</b>) TUG<sub>ME</sub>, (<b>b</b>) TUG<sub>MC</sub>, (<b>c</b>) TUG<sub>VF</sub> and (<b>d</b>) TUG<sub>RE</sub> performance.</p>
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12 pages, 1538 KiB  
Article
Remote Parenting in Families Experiencing, or at Risk of, Homelessness: A Study Based on Grounded Theory
by Filipa Maria Reinhardt Andrade, Ana Resende, Maria Clara Roquette-Viana and Amélia Simões Figueiredo
Int. J. Environ. Res. Public Health 2024, 21(9), 1184; https://doi.org/10.3390/ijerph21091184 - 5 Sep 2024
Viewed by 399
Abstract
The situation/risk of family homelessness presents multiple interrelated issues. It has considerable negative consequences, namely the deterioration of the family members’ health and well-being, and alterations in the family’s dynamics, with parents sometimes being separated from their children. The aim of this research [...] Read more.
The situation/risk of family homelessness presents multiple interrelated issues. It has considerable negative consequences, namely the deterioration of the family members’ health and well-being, and alterations in the family’s dynamics, with parents sometimes being separated from their children. The aim of this research was to understand how parenting takes place in families experiencing, or at risk of, homelessness. The conducted study falls within the qualitative paradigm, using Strauss and Corbin’s version of the Grounded Theory methodology. Three main categories emerged, supported by all the participating families: “Meaning of Parenthood”, “Key Events”, and “Transition Circumstances”. These categories were translated into facilitating/inhibiting factors, within the following dimensions: “Individual”, “Family”, and “Society”. We were able to conclude that, in the population under study, parenting is restricted, being mostly exerted in a remote manner. Furthermore, it takes on different forms, depending on the specific homelessness situation/risk. In families at risk of homelessness, we identified “Remote Parenting with Maintained Parental Authority”, as well as “Restricted Parenting”, when the children still lived with their parents. On the other hand, in families experiencing homelessness, we identified “Remote Parenting with Maintained Parental Authority”, “Unilateral Remote Parenting”, “Interrupted Parenting”, and the “Total Disruption of Parenting”. Full article
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<p>Parenting response patterns of families experiencing, or at risk of, homelessness. <b>Caption</b>—<span class="html-fig-inline" id="ijerph-21-01184-i001"><img alt="Ijerph 21 01184 i001" src="/ijerph/ijerph-21-01184/article_deploy/html/images/ijerph-21-01184-i001.png"/></span>—<b>Roofless;</b> <span class="html-fig-inline" id="ijerph-21-01184-i002"><img alt="Ijerph 21 01184 i002" src="/ijerph/ijerph-21-01184/article_deploy/html/images/ijerph-21-01184-i002.png"/></span>—<b>Housing First;</b> <span class="html-fig-inline" id="ijerph-21-01184-i003"><img alt="Ijerph 21 01184 i003" src="/ijerph/ijerph-21-01184/article_deploy/html/images/ijerph-21-01184-i003.png"/></span>—<b>Houseless;</b> <span class="html-fig-inline" id="ijerph-21-01184-i004"><img alt="Ijerph 21 01184 i004" src="/ijerph/ijerph-21-01184/article_deploy/html/images/ijerph-21-01184-i004.png"/></span>—<b>Living with Family;</b> <span class="html-fig-inline" id="ijerph-21-01184-i005"><img alt="Ijerph 21 01184 i005" src="/ijerph/ijerph-21-01184/article_deploy/html/images/ijerph-21-01184-i005.png"/></span>—Inadequate Housing; <span class="html-fig-inline" id="ijerph-21-01184-i006"><img alt="Ijerph 21 01184 i006" src="/ijerph/ijerph-21-01184/article_deploy/html/images/ijerph-21-01184-i006.png"/></span>—Insecure Housing.</p>
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18 pages, 1843 KiB  
Article
Capturing Tail Risks in Cryptomarkets: A New Systemic Risk Approach
by Itai Barkai, Elroi Hadad, Tomer Shushi and Rami Yosef
J. Risk Financial Manag. 2024, 17(9), 397; https://doi.org/10.3390/jrfm17090397 - 5 Sep 2024
Viewed by 383
Abstract
Using daily returns of Bitcoin, Litecoin, Ripple and Stellar, we introduce a novel risk measure for quantitative-risk management in the cryptomarket that accounts for the significant co-movements between cryptocurrencies. We find that our model has a lower error margin when forecasting the extent [...] Read more.
Using daily returns of Bitcoin, Litecoin, Ripple and Stellar, we introduce a novel risk measure for quantitative-risk management in the cryptomarket that accounts for the significant co-movements between cryptocurrencies. We find that our model has a lower error margin when forecasting the extent of future losses than traditional risk measures, such as Value-at-Risk and Expected Shortfall. Most notably, we observe this in Litecoin’s results, where Expected Shortfall, on average, overestimates the potential fall in the price of Litecoin by 8.61% and underestimates it by 3.92% more than our model. This research shows that traditional risk measures, while not necessarily inappropriate, are imperfect and incomplete representations of risk when it comes to the cryptomarket. Our model provides a suitable alternative for risk managers, who prioritize lower error margins over failure rates, and highlights the value in exploring how risk measures that incorporate the unique characteristics of cryptocurrencies can be used to supplement and complement traditional risk measures. Full article
(This article belongs to the Special Issue Financial Technologies (Fintech) in Finance and Economics)
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<p>Scaled cryptocurrency prices over time. <b>Notes</b>: The figure shows the co-movements between different cryptocurrency prices. All prices have been scaled as follows: Bitcoin is divided by 350, Litecoin is divided by 10, Ripple is multiplied by 10, and Stellar is multiplied by 10.</p>
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<p>Cryptocurrency log returns separated into drawup and drawdown periods. <b>Notes</b>: Drawup periods describe low-risk market periods characterized by predominantly positive returns; drawdown periods denote predominantly negative returns and higher risk.</p>
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<p>Bull and bear regimes for all cryptocurrencies. <b>Notes</b>: The figure illustrates bull and bear regimes over the period from 8 August 2015 to 21 July 2019.</p>
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<p>Litecoin loss forecasts by systemic and traditional risk measures. <b>Notes</b>: The figure illustrates Litecoin daily loss forecasts from 8 August 2015 to 21 July 2019. Due to high volatility, the figure depicts the loss forecast in different timeframes.</p>
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<p>Bitcoin loss forecasts by systemic and traditional risk measures. <b>Notes</b>: The figure illustrates Bitcoin daily loss forecasts from 8 August 2015 to 21 July 2019. Due to high volatility, the figure depicts the loss forecast in different timeframes.</p>
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<p>Ripple loss forecasts by systemic and traditional risk measures. <b>Notes</b>: The figure illustrates Ripple daily loss forecasts from 8 August 2015 to 21 July 2019. Due to high volatility, the figure depicts the loss forecast in different timeframes.</p>
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<p>Stellar loss forecasts by systemic and traditional risk measures. <b>Notes</b>: The figure illustrates Stellar daily loss forecasts from 8 August 2015 to 21 July 2019. Due to high volatility, the figure depicts the loss forecast in different timeframes.</p>
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15 pages, 1277 KiB  
Article
Positive Selection Drives the Evolution of the Structural Maintenance of Chromosomes (SMC) Complexes
by Diego Forni, Alessandra Mozzi, Manuela Sironi and Rachele Cagliani
Genes 2024, 15(9), 1159; https://doi.org/10.3390/genes15091159 - 3 Sep 2024
Viewed by 307
Abstract
Structural Maintenance of Chromosomes (SMC) complexes are an evolutionary conserved protein family. In most eukaryotes, three SMC complexes have been characterized, as follows: cohesin, condensin, and SMC5/6 complexes. These complexes are involved in a plethora of functions, and defects in SMC genes can [...] Read more.
Structural Maintenance of Chromosomes (SMC) complexes are an evolutionary conserved protein family. In most eukaryotes, three SMC complexes have been characterized, as follows: cohesin, condensin, and SMC5/6 complexes. These complexes are involved in a plethora of functions, and defects in SMC genes can lead to an increased risk of chromosomal abnormalities, infertility, and cancer. To investigate the evolution of SMC complex genes in mammals, we analyzed their selective patterns in an extended phylogeny. Signals of positive selection were identified for condensin NCAPG, for two SMC5/6 complex genes (SMC5 and NSMCE4A), and for all cohesin genes with almost exclusive meiotic expression (RAD21L1, REC8, SMC1B, and STAG3). For the latter, evolutionary rates correlate with expression during female meiosis, and most positively selected sites fall in intrinsically disordered regions (IDRs). Our results support growing evidence that IDRs are fast evolving, and that they most likely contribute to adaptation through modulation of phase separation. We suggest that the natural selection signals identified in SMC complexes may be the result of different selective pressures: a host-pathogen arms race in the condensin and SMC5/6 complexes, and an intragenomic conflict for meiotic cohesin genes that is similar to that described for centromeres and telomeres. Full article
(This article belongs to the Section Molecular Genetics and Genomics)
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<p>Evolutionary rates in SMC complexes. (<b>a</b>) Comparison of evolutionary rates. The distribution of dN/dS values for more than 9000 genes in a representative mammalian phylogeny [<a href="#B60-genes-15-01159" class="html-bibr">60</a>] is shown. The hatched red lines correspond to the 10th, 50th, and 90th percentiles. The dN/dS values of the genes we analyzed are indicated. The inset shows the correlation between the dN/dS values we calculated and those previously reported by Ebel and coworkers for 11 SMC complex genes (<span class="html-italic">NCAPD2</span>, <span class="html-italic">NCAPD3</span>, <span class="html-italic">NCAPG</span>, <span class="html-italic">NCAPH</span>, <span class="html-italic">NCAPH2</span>, <span class="html-italic">RAD21</span>, <span class="html-italic">RAD21L</span>, <span class="html-italic">REC8</span>, <span class="html-italic">SMC1B</span>, <span class="html-italic">SMC4</span>, <span class="html-italic">STAG3</span>). (<b>b</b>) Boxplot representation of dN−dS values calculated for meiotic and mitotic Cohesin, Condensin, and SMC5/6 genes. Statistical significance was assessed by Nemenyi post hoc pairwise comparison after a Kruskal–Wallis test. All comparisons are significant, with a <span class="html-italic">p</span>-value &lt; 0.001.</p>
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<p>Domain structures of SMC complexes. Schematic domain structures of the 7 proteins with evidence of positive selection are drawn to scale. Domains are defined using the InterPro (<a href="https://www.ebi.ac.uk/interpro/" target="_blank">https://www.ebi.ac.uk/interpro/</a>, accessed on 15 July 2024) classification. The gray-shaded areas represent IDRs identified by the Metapredict tool based on human proteins. The red arrows denote positively selected sites as obtained from positive selection analysis. ParSe sequences are represented in blue.</p>
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<p>Evolutionary rates and gene expression in meiosis. Average dN/dS for all SMC complex genes is plotted against the log2 fold-change (FC) of gene expression in the leptotene or pachytene stages vs. the pre-meiotic stage of mouse oogenesis or spermatogenesis. Kendall’s correlation coefficients are also reported.</p>
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20 pages, 2732 KiB  
Article
Sources Analysis and Health Risk Assessment of Heavy Metals in Street Dust from Urban Core of Zhengzhou, China
by Minghao Ren, Yali Deng, Wenshan Ni, Jingjing Su, Yao Tong, Xiao Han, Fange Li, Hongjian Wang, Fei Zhao, Xiaoxiao Huang and Zhiquan Huang
Sustainability 2024, 16(17), 7604; https://doi.org/10.3390/su16177604 - 2 Sep 2024
Viewed by 966
Abstract
Fifty-one street dust samples were systematically collected from the urban core of Zhengzhou, China, and analyzed for potentially toxic metals. The concentrations of vanadium (V), manganese (Mn), copper (Cu), zinc (Zn), arsenic (As), lead (Pb), and nickel (Ni) in the samples surpassed the [...] Read more.
Fifty-one street dust samples were systematically collected from the urban core of Zhengzhou, China, and analyzed for potentially toxic metals. The concentrations of vanadium (V), manganese (Mn), copper (Cu), zinc (Zn), arsenic (As), lead (Pb), and nickel (Ni) in the samples surpassed the background values of the local soil, indicating a notable potential for contamination. Spatially, the traffic area was the most polluted with a total heavy metal concentration of Cu, Zn, As, Pb, and Ni, while the pollution levels were lower in the culture and education area and commercial area with total concentrations of V and Mn. Seasonal variations were discerned in the concentrations of heavy metals, with V, Cu, Zn, and As exhibiting heightened levels during the fall and winter, while Mn, Ni, and Pb reached peaks in the spring season. Zn exhibited the highest mean geo-accumulation index (Igeo) value at 2.247, followed by Cu at 2.019, Pb at 0.961, As at 0.590, Ni at 0.126, Mn at −0.178, and V at −0.359. The potential ecological risk index (RI) in the traffic-intensive area markedly exceeded other functional areas. Health risk assessments showed that children were more vulnerable to heavy metal exposure than adults, particularly through the ingestion pathway. Correlation analysis, principal component analysis (PCA), and cluster analysis (CA) were applied in conjunction with the spatial–temporal concentration patterns across various functional areas to ascertain the plausible sources of heavy metal pollutants. The results indicated that heavy metals in the urban street dust of Zhengzhou were multifaceted, stemming from natural processes and diverse anthropogenic activities such as coal burning, industrial emissions, traffic, and construction operations. Full article
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<p>Sampling sites in the study area. (<b>a</b>) Location of Zhengzhou city in Henan. (<b>b</b>) Central urban region of Zhengzhou city and its county-level cities. (<b>c</b>) Study area and sampling sites in Zhengzhou, China. Note: S1, culture and education area; S2, traffic area; S3, commercial area.</p>
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<p>The distribution of mean concentrations for heavy metals in the urban street dust of Zhengzhou (mg·kg<sup>−1</sup>, dry weight) from three functional areas. Note: S1, culture and education area; S2, traffic area; S3, commercial area.</p>
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<p>Seasonal variations in heavy metal concentrations. (<b>a</b>) The mean concentrations of heavy metals. (<b>b</b>) Seasonal variations in heavy metal concentrations from three functional areas. Note: (<b>a</b>) The ends of the half box represent the 25th and 75th percentile values, respectively. The horizontal line at the bottom and top denotes the minimum and maximum concentration. The data distribution is depicted by colorful dots. (<b>b</b>) Data are represented as the mean ± 95% CI (confidence interval). The solid circle represents the mean heavy metal concentrations.</p>
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<p>A box plot of the geo-accumulation index (<span class="html-italic">I<sub>geo</sub></span>) for selected heavy metals in urban road dust. Note: The dashed line denotes the threshold of contamination assessment and their classification values are listed in <a href="#app1-sustainability-16-07604" class="html-app">Table S1</a>. The black horizontal line in the middle of the box represents the median values, while the solid black square in the box represents the mean values. The ends of the box represent the 25th and 75th percentile values, respectively. The horizontal line in the bottom and top of the box plots denotes a multiplication of the interquartile range (IQR) by 1.5.</p>
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<p>A source analysis of heavy metal contamination in urban street dust. (<b>a</b>) A heatmap illustrating the Pearson correlation coefficients of heavy metals. (<b>b</b>) Diagrams of three-dimensional space: three principal components for seven heavy metals in Zhengzhou. (<b>c</b>) The results of the cluster analysis of heavy metals obtained by Ward’s hierarchical clustering method (the distances reflect the degree of correlation between different elements). Note: (<b>a</b>) one (*) and two (**) asterisks indicate that the correlation is significant at the 0.05 level (two-tailed) and the 0.01 level (two-tailed), respectively. The values of correlation coefficients have been labeled in the figure.</p>
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23 pages, 511 KiB  
Review
Nepali Migrant Workers and Their Occupational Health Hazards in the Workplace: A Scoping Review
by Sharada Prasad Wasti, Emmanuel Babatunde, Santosh Bhatta, Ayushka Shrestha, Pratikshya Wasti and Vijay S. GC
Sustainability 2024, 16(17), 7568; https://doi.org/10.3390/su16177568 - 1 Sep 2024
Viewed by 861
Abstract
An increasing number of people are relocating to search for work, leading to substantial implications for both local and global health. Approximately 3.6% of the global population (281 million) migrates annually. Nepal has experienced a notable surge in labour migration in recent years, [...] Read more.
An increasing number of people are relocating to search for work, leading to substantial implications for both local and global health. Approximately 3.6% of the global population (281 million) migrates annually. Nepal has experienced a notable surge in labour migration in recent years, with a substantial proportion of its residents actively seeking work opportunities abroad. Understanding work-related risks is crucial for informing policies, interventions, and practices that can improve the welfare of this hard-to-reach population. This scoping review aims to systematically identify and analyse occupational health hazards encountered by Nepali migrant workers employed overseas. Medline, Scopus, Directory of Open Access Journals (DOAJ), and the NepJOL databases were systematically searched for primary research papers published in English up to July 2024. Relevant data, including workplace hazards and their impact on health outcomes, were extracted and narratively synthesised by highlighting key themes in the existing literature. A total of 24 articles met the inclusion criteria and were included in this review. Of these, twelve studies were conducted in Nepal, five in Gulf countries, four in Malaysia, two in Hong Kong, and one each in India and Korea. Workplace injuries (motor vehicle injuries, machinery injuries, falls from a height, and falls on a heavy object), poor working environment (including long working hours, work without leave, discrepancy in pay scale, limited access to drinking water and toilet/bathroom facilities), workplace abuse, sexual abuse, and torture were identified as key occupational health hazards faced by the Nepali migrant workers abroad. Multi-level intervention strategies, such as safety training standards, improving working conditions, and eliminating exploitative labour practices, are critical to improving occupational health and safety standards for Nepali migrant workers abroad. This includes creating a supportive working environment where employees can easily and timely access health services as needed. Full article
(This article belongs to the Section Health, Well-Being and Sustainability)
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<p>PRISMA-ScR flowchart of this study’s search and selection process.</p>
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11 pages, 349 KiB  
Article
Improvement in Body’s Dynamic Adaptation during Walking with Vestibular Rehabilitation Therapy in Patients with Cerebellopontine Angle Tumor Resection
by Natasa Kos, Tomaz Velnar, Marusa Brcar and Marko Brcar
Life 2024, 14(9), 1100; https://doi.org/10.3390/life14091100 - 31 Aug 2024
Viewed by 445
Abstract
Background: Our study aimed to investigate the effects of vestibular rehabilitation therapy on functional gait performance in patients with balance disorders. Methods: A total of 40 post-operative patients with balance disorders were included in the study. They were divided into two groups and [...] Read more.
Background: Our study aimed to investigate the effects of vestibular rehabilitation therapy on functional gait performance in patients with balance disorders. Methods: A total of 40 post-operative patients with balance disorders were included in the study. They were divided into two groups and participated in a vestibular rehabilitation program during their hospital stay. After discharge, the intervention group performed vestibular exercises at home, while the control group did not. Balance was assessed using the Functional Gait Assessment Scale at discharge and three months after surgery. Results: The intervention group included 15 women and 5 men with an average age of 45 years, while the control group included 7 women and 13 men with an average age of 50 years. Three months after surgery, the change in Functional Gait Assessment (FGA) scores exceeded the clinically significant threshold of 5 points in 17 patients in the intervention group and 14 in the control group. There was a statistically significant difference in FGA progression between the groups (p = 0.034). After three months post-surgery, 7 patients in the intervention group experienced falls compared to 12 in the control group. Conclusion: Three months after surgery, we observed a significant improvement in the performance of balance tasks while walking and a lower risk of falls in the intervention group. Full article
(This article belongs to the Special Issue Feature Paper in Physiology and Pathology: 2nd Edition)
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<p>Graphical distribution of changes in FGA measurements for all patients from both groups before hospital discharge and three months after surgery.</p>
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12 pages, 555 KiB  
Article
Occupational Accidents, Injuries, and Associated Factors among Migrant and Domestic Construction Workers in Saudi Arabia
by Musaad Alruwaili, Patricia Carrillo, Robby Soetanto and Fehmidah Munir
Buildings 2024, 14(9), 2714; https://doi.org/10.3390/buildings14092714 - 30 Aug 2024
Viewed by 465
Abstract
The number of migrant workers in Saudi Arabia (SA) has gradually increased, particularly in the construction industry, where migrant workers make up 89% of the workforce. Migrant workers frequently experience exposure to dangerous working conditions and increased risk for occupational injury and hazards [...] Read more.
The number of migrant workers in Saudi Arabia (SA) has gradually increased, particularly in the construction industry, where migrant workers make up 89% of the workforce. Migrant workers frequently experience exposure to dangerous working conditions and increased risk for occupational injury and hazards due to the work they typically perform. Despite this, there is a lack of comprehensive studies comparing occupational accidents and injuries between migrant and domestic workers. To address this challenge, this study explores the differences between migrant and domestic workers’ injuries and occupational accident rates in SA’s construction industry. Data were analyzed from reported accidents and injuries obtained from the General Organisation for Social Insurance (GOSI) between 2014 and 2019. Chi-square test was used to examine the associations of occupational accidents and injuries among migrant and domestic workers. Migrant workers experienced higher incidences of falls, strikes, collisions, abrasions (wounds caused by scraping), bodily reactions (e.g., chemical reactions), and car accidents compared to domestic workers. Furthermore, migrant workers aged 30–39 and domestic workers aged 20–29 experienced more severe injuries and higher seasonal mortality rates during the six-year period examined (2014–2019). In addition, domestic workers achieved a higher proportion of full recovery across all types of accidents, except for transport and car accidents related to construction. The findings emphasize the need for ongoing safety education, training, and improved safety measures to protect the health and safety of construction workers, especially migrant workers. Full article
(This article belongs to the Section Construction Management, and Computers & Digitization)
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<p>Distribution of accidents (%) by season each year in Saudi Arabia’s construction industry.</p>
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8 pages, 1717 KiB  
Proceeding Paper
Gait Analysis and Fall Risk Assessment in Different Age Groups: A Comparative Study
by Thanaporn Sukpramote and Wongwit Senavongse
Eng. Proc. 2024, 74(1), 19; https://doi.org/10.3390/engproc2024074019 - 28 Aug 2024
Viewed by 135
Abstract
Daily walking reflects the quality of life concerning physical status and its association with the risk of falls. Abnormal walking can lead to injuries and increase the likelihood of future falls. It has been found that older adults are more prone to falls [...] Read more.
Daily walking reflects the quality of life concerning physical status and its association with the risk of falls. Abnormal walking can lead to injuries and increase the likelihood of future falls. It has been found that older adults are more prone to falls than younger persons. However, there is limited research on gait analysis in older adults. Thus, we analyzed gait parameters, involving 10 participants aged between 20 and 30 years old, and 10 participants aged 50 years and older, using the Gait Analysis System (LONGGOOD Meditech Ltd., Taipei, Taiwan), which automatically positions the human body and GaitBEST. GaitBEST is used for analyzing and calculating key timing points and displacement values from the Kinect detector as it captures the location of joint points and adjusts them to the program. After the gait testing, the result is displayed immediately. Each volunteer did not have any surgery that impacted their walking and signed a written informed consent statement before the study. The volunteers walked on a straight flat surface for 4.2 m, repeating the walking test five times at a self-determined comfortable speed. Subsequently, a comparative analysis of the gait parameter outcomes was performed using a parametric test by a t-test. The results showed the balance parameters of both groups significantly differed in the head sway range (p = 0.008), head tilt range (p = 0.018), and pelvis tilt range (p = 0.003). The younger group exhibited better postural control than the other group. The spatiotemporal parameters, stride length, and step length during walking were also significantly different at p = 0.001. This indicated that the older group had shorter lengths compared to the other group, leading to a significant difference in the percentage of falls and functional loss at p = 0.021 and 0.023, respectively. The result of this study assists in examining and assessing the physical condition, preventing falls, optimizing walking efficiency, preventing injuries, and reducing the falling risk. Full article
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<p>Straight flat floor walkways and starting and ending points for laboratory walking tests.</p>
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<p>Experiment with walking using the Gait Analysis System.</p>
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<p>Comparison of significant balance parameters, which includes head sway range, head tilt range, and pelvis tilt range between the volunteers aged 20–39 years group and volunteers aged 50 years and above group.</p>
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<p>Comparison of the significant spatiotemporal parameters, which includes stride length and step length between the volunteers aged 20–39 years group and volunteers aged 50 years and above group.</p>
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<p>Comparison of the significant health risk score parameters, which includes the risk of falling and functional loss between the volunteers aged 20–39 years group and volunteers aged 50 years and above group.</p>
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