Search Results (705)

Background: Prostate cancer is a leading cause of cancer-related deaths in men worldwide, making accurate diagnosis critical for effective treatment. Recent advancements in artificial intelligence (AI) and machine learning (ML) have shown promise in improving the diagnostic accuracy of prostate cancer. Objectives: This systematic review aims to evaluate the effectiveness of AI-based tools in diagnosing prostate cancer using MRI, with a focus on accuracy, specificity, sensitivity, and clinical utility compared to conventional diagnostic methods. Methods: A comprehensive search was conducted across PubMed, Embase, Ovid MEDLINE, Web of Science, Cochrane Library, and Institute of Electrical and Electronics Engineers (IEEE) Xplore for studies published between 2019 and 2024. Inclusion criteria focused on full-text, English-language studies involving AI for Magnetic Resonance Imaging (MRI) -based prostate cancer diagnosis. Diagnostic performance metrics such as area under curve (AUC), sensitivity, and specificity were analyzed, with risk of bias assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. Results: Seven studies met the inclusion criteria, employing various AI techniques, including deep learning and machine learning. These studies reported improved diagnostic accuracy (with AUC scores of up to 97%) and moderate sensitivity, with performance varying based on training data quality and lesion characteristics like Prostate Imaging Reporting and Data System (PI-RADS) scores. Conclusions: AI has significant potential to enhance prostate cancer diagnosis, particularly when used for second opinions in MRI interpretations. While these results are promising, further validation in diverse populations and clinical settings is necessary to fully integrate AI into standard practice. Full article

Sentiment analysis is a crucial tool for measuring public opinion and understanding human communication across digital social media platforms. However, due to linguistic complexities and limited data or computational resources, it is under-represented in many African languages. While state-of-the-art Afrocentric pre-trained language models (PLMs) have been developed for various natural language processing (NLP) tasks, their applications in eXplainable Artificial Intelligence (XAI) remain largely unexplored. In this study, we propose a novel approach that combines Afrocentric PLMs with XAI techniques for sentiment analysis. We demonstrate the effectiveness of incorporating attention mechanisms and visualization techniques in improving the transparency, trustworthiness, and decision-making capabilities of transformer-based models when making sentiment predictions. To validate our approach, we employ the SAfriSenti corpus, a multilingual sentiment dataset for South African under-resourced languages, and perform a series of sentiment analysis experiments. These experiments enable comprehensive evaluations, comparing the performance of Afrocentric models against mainstream PLMs. Our results show that the Afro-XLMR model outperforms all other models, achieving an average F1-score of 71.04% across five tested languages, and the lowest error rate among the evaluated models. Additionally, we enhance the interpretability and explainability of the Afro-XLMR model using Local Interpretable Model-Agnostic Explanations (LIME) and Shapley Additive Explanations (SHAP). These XAI techniques ensure that sentiment predictions are not only accurate and interpretable but also understandable, fostering trust and reliability in AI-driven NLP technologies, particularly in the context of African languages. Full article

The widespread use of machine and deep learning algorithms for anomaly detection has created a critical need for robust explanations that can identify the features contributing to anomalies. However, effective evaluation methodologies for anomaly explanations are currently lacking, especially those that compare the explanations against the true underlying causes, or ground truth. This paper aims to address this gap by introducing a rigorous, ground-truth-based framework for evaluating anomaly explanation methods, which enables the assessment of explanation correctness and robustness—key factors for actionable insights in anomaly detection. To achieve this, we present an innovative benchmark dataset of digital circuit truth tables with model-based anomalies, accompanied by local ground truth explanations. These explanations were generated using a novel algorithm designed to accurately identify influential features within each anomaly. Additionally, we propose an evaluation methodology based on correctness and robustness metrics, specifically tailored to quantify the reliability of anomaly explanations. This dataset and evaluation framework are publicly available to facilitate further research and standardize evaluation practices. Our experiments demonstrate the utility of this dataset and methodology by evaluating common model-agnostic explanation methods in an anomaly detection context. The results highlight the importance of ground-truth-based evaluation for reliable and interpretable anomaly explanations, advancing both theory and practical applications in explainable AI. This work establishes a foundation for rigorous, evidence-based assessments of anomaly explanations, fostering greater transparency and trust in AI-driven anomaly detection systems. Full article

Unmanned autonomous systems (UASs), including drones and robotics, are widely employed across various fields. Despite significant advances in AI-enhanced intelligent systems, there remains a notable deficiency in the interpretability and comprehensive quantitative evaluation of these systems. The existing literature has primarily focused on constructing evaluation frameworks and methods, but has often overlooked the rationality and reliability of these methods. To address these challenges, this paper proposes an innovative optimization evaluation method for data-driven unmanned autonomous systems. By optimizing the weights of existing indicators based on data distribution characteristics, this method enhances the stability and reliability of assessment outcomes. Furthermore, interpretability techniques such as Local Interpretable Model-agnostic Explanations (LIMEs) and Partial Dependence Plots (PDPs) were employed to verify the effectiveness of the designed evaluation indicators, thereby ensuring the robustness of the evaluation system. The experimental results validated the effectiveness of the proposed approach. Full article

Background/Objectives: Glaucoma is the leading cause of irreversible blindness, with a significant proportion of cases remaining undiagnosed globally. The interpretation of optic disc and retinal nerve fibre layer images poses challenges for optometrists and ophthalmologists, often leading to misdiagnosis. AI has the potential to improve diagnosis. This study aims to validate an AI system (a convolutional neural network based on the Inception-v3 architecture) for detecting glaucomatous optic neuropathy (GON) using colour fundus photographs from a UK population and to compare its performance against Australian optometrists. Methods: A retrospective external validation study was conducted, comparing AI’s performance with that of 11 AHPRA-registered optometrists in Australia on colour retinal photographs, evaluated against a reference (gold) standard established by a panel of glaucoma specialists. Statistical analyses were performed using sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC). Results: For referable GON, the sensitivity of the AI (33.3% [95%CI: 32.4–34.3) was significantly lower than that of optometrists (65.1% [95%CI: 64.1–66.0]), p < 0.0001, although with significantly higher specificity (AI: 97.4% [95%CI: 97.0–97.7]; optometrists: 85.5% [95%CI: 84.8–86.2], p < 0.0001). The optometrists demonstrated significantly higher AUROC (0.753 [95%CI: 0.744–0.762]) compared to AI (0.654 [95%CI: 0.645–0.662], p < 0.0001). Conclusion: The AI system exhibited lower performance than optometrists in detecting referable glaucoma. Our findings suggest that while AI can serve as a screening tool, both AI and optometrists have suboptimal performance for the nuanced diagnosis of glaucoma using fundus photographs alone. Enhanced training with diverse populations for AI is essential for improving GON detection and addressing the significant challenge of undiagnosed cases. Full article

In this work we study the use of artificial intelligence models, particularly focusing on transfer learning and interpretability, to predict polymer properties. Given the challenges imposed by data scarcity in polymer science, transfer learning offers a promising solution by using learnt features of models pre-trained on other datasets. We conducted a comparative analysis of direct modelling and transfer learning-based approaches using a polyacrylates’ glass transitions dataset as a proof-of-concept study. The AI models utilized tokenized SMILES strings to represent polymer structures, with convolutional neural networks processing these representations to predict Tg. To enhance model interpretability, Shapley value analysis was employed to assess the contribution of specific chemical groups to the predictions. The results indicate that while transfer learning provides robust predictive capabilities, direct modelling on polymer-specific data offers superior performance, particularly in capturing the complex interactions influencing Tg. This work highlights the importance of model interpretability and the limitations of applying molecular-level models to polymer systems. Full article

Industries are increasingly adopting digital systems to improve control and accessibility by providing real-time monitoring and early alerts for potential issues. While digital transformation fuels exponential growth, it exposes these industries to cyberattacks. For critical sectors such as nuclear power plants, a cyberattack not only risks damaging the facility but also endangers human lives. In today’s digital world, enormous amounts of data are generated, and the analysis of these data can help ensure effectiveness, including security. In this study, we analyzed the data using a deep learning model for early detection of abnormal behavior. We first examined the Asherah Nuclear Power Plant simulator by initiating three different cyberattacks, each targeting a different system, thereby collecting and analyzing data from the simulator. Second, a Bi-LSTM model was used to detect anomalies in the simulator, which detected it before the plant’s protection system was activated in response to a threat. Finally, we applied explainable AI (XAI) to acquire insight into how distinctive features contribute to the detection of anomalies. XAI provides valuable explanations of model behavior by revealing how specific features influence anomaly detection during attacks. This research proposes an effective anomaly detection technique and interpretability to better understand counter-cyber threats in critical industries, such as nuclear plants. Full article

The Future Internet aims to revolutionize digital interaction by integrating advanced technologies like AI and IoT, enabling a dynamic and resilient network. It envisions emotionally intelligent systems that can interpret and respond to human feelings, creating immersive, empathy-driven learning experiences. This evolution aspires to form a responsive digital ecosystem that seamlessly connects technology and human emotion. This paper presents a computational model aimed at enhancing the emotional aspect of learning experiences within museum environments. The model is designed to represent and manage affective and emotional feedback, with a focus on how emotions can significantly impact the learning process in a museum context. The proposed model seeks to identify and quantify emotions during a visitor’s engagement with museum exhibits. To achieve this goal, we primarily explored the following: (i) methods and techniques for assessing and recognizing emotional responses in museum visitors, (ii) feedback management strategies based on the detection of visitors’ emotional states. Then, the methodology was tested on 1000 cases via specific questionnaire forms, along with the presentation of images and short videos, and the results of data analysis are reported. The findings contribute toward establishing a comprehensive methodology for the identification and quantification of the emotional state of museum visitors. Full article

The integration of artificial intelligence (AI) in cytopathology is an emerging field with transformative potential, aiming to enhance diagnostic precision and operational efficiency. This umbrella review seeks to identify prevailing themes, opportunities, challenges, and recommendations related to AI in cytopathology. Utilizing a standardized checklist and quality control procedures, this review examines recent advancements and future implications of AI technologies in this domain. Twenty-one review studies were selected through a systematic process. AI has demonstrated promise in automating and refining diagnostic processes, potentially reducing errors and improving patient outcomes. However, several critical challenges need to be addressed to realize the benefits of AI fully. This review underscores the necessity for rigorous validation, ongoing empirical data on diagnostic accuracy, standardized protocols, and effective integration with existing clinical workflows. Ethical issues, including data privacy and algorithmic bias, must be managed to ensure responsible AI applications. Additionally, high costs and substantial training requirements present barriers to widespread AI adoption. Future directions highlight the importance of applying successful integration strategies from histopathology and radiology to cytopathology. Continuous research is needed to improve model interpretability, validation, and standardization. Developing effective strategies for incorporating AI into clinical practice and establishing comprehensive ethical and regulatory frameworks will be crucial for overcoming these challenges. In conclusion, while AI holds significant promise for advancing cytopathology, its full potential can only be achieved by addressing challenges related to validation, cost, and ethics. This review provides an overview of current advancements, identifies ongoing challenges, and offers a roadmap for the successful integration of AI into diagnostic cytopathology, informed by insights from related fields. Full article

Background: As the demand for early and accurate diagnosis of autism spectrum disorder (ASD) increases, the integration of machine learning (ML) and explainable artificial intelligence (XAI) is emerging as a critical advancement that promises to revolutionize intervention strategies by improving both accuracy and transparency. Methods: This paper presents a method that combines XAI techniques with a rigorous data-preprocessing pipeline to improve the accuracy and interpretability of ML-based diagnostic tools. Our preprocessing pipeline included outlier removal, missing data handling, and selecting pertinent features based on clinical expert advice. Using R and the caret package (version 6.0.94), we developed and compared several ML algorithms, validated using 10-fold cross-validation and optimized by grid search hyperparameter tuning. XAI techniques were employed to improve model transparency, offering insights into how features contribute to predictions, thereby enhancing clinician trust. Results: Rigorous data-preprocessing improved the models’ generalizability and real-world applicability across diverse clinical datasets, ensuring a robust performance. Neural networks and extreme gradient boosting models achieved the best performance in terms of accuracy, precision, and recall. XAI techniques demonstrated that behavioral features significantly influenced model predictions, leading to greater interpretability. Conclusions: This study successfully developed highly precise and interpretable ML models for ASD diagnosis, connecting advanced ML methods with practical clinical application and supporting the adoption of AI-driven diagnostic tools by healthcare professionals. This study’s findings contribute to personalized intervention strategies and early diagnostic practices, ultimately improving outcomes and quality of life for individuals with ASD. Full article

Maternal mortality (MM) is considered one of the major worldwide concerns. Despite the advances of artificial intelligence (AI) in healthcare, the lack of transparency in AI models leads to reluctance to adopt them. Employing explainable artificial intelligence (XAI) thus helps improve the transparency and effectiveness of AI-driven healthcare solutions. Accordingly, this article proposes a complete framework integrating an Internet of Medical Things (IoMT) architecture with an XAI-based deep learning model. The IoMT system continuously monitors pregnant women’s vital signs, while the XAI model analyzes the collected data to identify risk factors and generate actionable insights. Additionally, an efficient IoMT transmission model is developed to ensure reliable data transfer with the best-required system quality of service (QoS). Further analytics are performed on the data collected from different regions in a country to address high-risk cities. The experiments demonstrate the effectiveness of the proposed framework by achieving an accuracy of 80% for patients and 92.6% for regional risk prediction and providing interpretable explanations. The XAI-generated insights empower healthcare providers to make informed decisions and implement timely interventions. Furthermore, the IoMT transmission model ensures efficient and secure data transfer. Full article

Background: The integration of artificial intelligence (AI) into radiology aims to improve diagnostic accuracy and efficiency, particularly in settings with limited access to expert radiologists and in times of personnel shortage. However, challenges such as insufficient validation in actual real-world settings or automation bias should be addressed before implementing AI software in clinical routine. Methods: This cross-sectional study in a maximum care hospital assesses the concordance between diagnoses made by a commercial AI-based software and conventional radiological methods augmented by AI for four major thoracic pathologies in chest X-ray: fracture, pleural effusion, pulmonary nodule and pneumonia. Chest radiographs of 1506 patients (median age 66 years, 56.5% men) consecutively obtained between January and August 2023 were re-evaluated by the AI software InferRead DR Chest^®. Results: Overall, AI software detected thoracic pathologies more often than radiologists (18.5% vs. 11.1%). In detail, it detected fractures, pneumonia, and nodules more frequently than radiologists, while radiologists identified pleural effusions more often. Reliability was highest for pleural effusions (0.63, 95%-CI 0.58–0.69), indicating good agreement, and lowest for fractures (0.39, 95%-CI 0.32–0.45), indicating moderate agreement. Conclusions: The tested software shows a high detection rate, particularly for fractures, pneumonia, and nodules, but hereby produces a nonnegligible number of false positives. Thus, AI-based software shows promise in enhancing diagnostic accuracy; however, cautious interpretation and human oversight remain crucial. Full article

Smart meter data provide an in-depth perspective on household energy usage. This research leverages on such data to enhance demand response (DR) programs through a novel application of ensemble clustering. Despite its promising capabilities, our literature review identified a notable under-utilization of ensemble clustering in this domain. To address this shortcoming, we applied an advanced ensemble clustering method and compared its performance with traditional algorithms, namely, K-Means++, fuzzy K-Means, Hierarchical Agglomerative Clustering, Spectral Clustering, Gaussian Mixture Models (GMMs), BIRCH, and Self-Organizing Maps (SOMs), across a dataset of 5567 households for a range of cluster counts from three to nine. The performance of these algorithms was assessed using an extensive set of evaluation metrics, including the Silhouette Score, the Davies–Bouldin Score, the Calinski–Harabasz Score, and the Dunn Index. Notably, while ensemble clustering often ranked among the top performers, it did not consistently surpass all individual algorithms, indicating its potential for further optimization. Unlike approaches that seek the algorithmically optimal number of clusters, our method proposes a practical six-cluster solution designed to meet the operational needs of utility providers. For this case, the best performing algorithm according to the evaluation metrics was ensemble clustering. This study is further enhanced by integrating Explainable AI (xAI) techniques, which improve the interpretability and transparency of our clustering results. Full article

The integration of artificial intelligence (AI) in healthcare management marks a significant advance in technological innovation, promising transformative effects on healthcare processes, patient care, and the efficacy of emergency responses. The scientific novelty of the study lies in its integrated approach, combining systematic review and predictive algorithms to provide a comprehensive understanding of AI’s role in improving healthcare management across different contexts. Covering the period between 2019 and 2023, which includes the global challenges posed by the COVID-19 pandemic, this research investigates the operational, strategic, and emergency response implications of AI adoption in the healthcare sector. It further examines how the impact of AI varies across temporal and geographical contexts. The study addresses two main research objectives: to explore how AI influences healthcare management in operational, strategic, and emergency response domains, and to identify variations in the impact of AI on healthcare management based on temporal and geographical contexts. Utilizing an integrated approach, we compared various prediction algorithms, including logistic regression, and interpreted the results through SHAP (SHapley Additive exPlanations) analysis. The findings reveal five key thematic areas: AI’s role in enhancing quality assurance, resource management, technological innovation, security, and the healthcare response to the COVID-19 pandemic. The study highlights AI’s positive influence on operational efficiency and strategic decision making, while also identifying challenges related to data privacy, ethical considerations, and the need for ongoing technological integration. These insights provide opportunities for targeted interventions to optimize AI’s impact in current and future healthcare landscapes. In conclusion, this work contributes to a deeper understanding of the role of AI in healthcare management and provides insights for policymakers, healthcare professionals, and researchers, offering a roadmap for addressing both the opportunities and challenges posed by AI integration in the healthcare sector. Full article

Background: Advances in medical image classification have recently benefited from general augmentation techniques. However, these methods often fall short in performance and interpretability. Objective: This paper applies the Unified Model Agnostic Computation (UMAC) framework specifically to the medical domain to demonstrate its utility in this critical area. Methods: UMAC is a model-agnostic methodology designed to develop machine learning approaches that integrate seamlessly with various paradigms, including self-supervised, semi-supervised, and supervised learning. By unifying and standardizing computational models and algorithms, UMAC ensures adaptability across different data types and computational environments while incorporating state-of-the-art methodologies. In this study, we integrate UMAC as a plug-and-play module within convolutional neural networks (CNNs) and Transformer architectures, enabling the generation of high-quality representations even with minimal data. Results: Our experiments across nine diverse 2D medical image datasets show that UMAC consistently outperforms traditional data augmentation methods, achieving a 1.89% improvement in classification accuracy. Conclusions: Additionally, by incorporating explainable AI (XAI) techniques, we enhance model transparency and reliability in decision-making. This study highlights UMAC’s potential as a powerful tool for improving both the performance and interpretability of medical image classification models. Full article