Search Results (37,439)

This paper addresses the need to contextualize sustainability standards and supply chain management in dairy value chains in East Africa, where milk perishability and limited cold storage significantly impact the industry. The study highlights the importance of localizing these standards, given the greater dependence on local supply chains following the COVID-19 pandemic. Drawing on milk standards literature and various interventions aimed at promoting systemic change, this review analyses the capacity of marginalized stakeholders in East Africa’s dairy value chains to meet sustainability standards, focusing particularly on the social dimensions of these standards. The findings indicate that compliance with sustainability and safety standards is predominantly restricted to formal dairy networks, which process less than 20 percent of milk produced in the region. Most milk sales occur through informal or unorganized markets, which face significant barriers to meeting international sustainability benchmarks. The review advocates for the alignment of international sustainability standards with the unique conditions of the informal markets dominating East Africa’s dairy sector. It suggests enhancing stakeholder capabilities and addressing regulatory barriers as necessary steps for improving compliance with these standards. The co-operative model is highlighted as a promising approach to integrating farmers and marginalized value chain actors into the formal sector, thereby facilitating incremental adoption of sustainability standards. The paper identifies strategic entry points for organizing and upgrading the supply chain, including capacity building, certification, and catalyzing farmer groups to compliance and productivity. Full article

The rapid growth in the use of AI techniques, mainly machine learning (ML), is revolutionizing different industries by significantly enhancing decision-making processes through data-driven insights. This study investigates the influence of using ML, particularly supervised and unsupervised learning, on rational decision-making (RDM) within Jordanian e-government, focusing on the mediating role of trust. By analyzing the experiences of middle-level management within e-government in Jordan, the findings underscore that ML positively impacts the rational decision-making process in e-government. It enables more efficient and effective data gathering, improves the accuracy of data analysis, enhances the speed and accuracy of evaluating decision alternatives, and improves the assessment of potential risks. Additionally, this study reveals that trust plays a critical role in determining the effectiveness of ML adoption for decision-making, acting as a pivotal mediator that can either facilitate or impede the integration of these technologies. This study provides empirical evidence of how trust not only enhances the utilization of ML but also amplifies its positive impact on governance. The findings highlight the necessity of cultivating trust to ensure the successful deployment of ML in public administration, thereby enabling a more effective and sustainable digital transformation. Despite certain limitations, the outcomes of this study offer substantial insights for researchers and government policymakers alike, contributing to the advancement of sustainable practices in the e-government domain. Full article

Protected and conserved areas are a key area-based strategy to address the biodiversity and climate change crises. Indicators are fundamental to understanding performance over time. The Digital Observatory for Protected Areas (DOPA) was born in 2013 as a set of open-access web services and applications to be used to assess, monitor, and report on protected and conserved areas. For over a decade, it has delivered over 50 indicators to support policy processes, national and regional governments, and practitioners. DOPA has also developed a versatile and efficient back-end approach that is widely applicable in other area-based conservation contexts. Here, we describe the methods and workflows behind DOPA’s back end and provide examples of policy relevant questions it can answer. We discuss the key advantages and limitations of this systematic and replicable approach and explore the use of this back-end architecture to inform progress in area-based conservation targets for the following decades. This approach, embedded in multiple services provided by the Knowledge Centre for Biodiversity of the European Commission (KCBD), can also support the implementation and monitoring of area-based targets of the Kunming Montreal Global Biodiversity Framework at international, regional, and national levels. Full article

This article will use syndemic theory to identify and analyze overlapping health and social conditions, focusing specifically on how gender-based violence is systemically interconnected with contemporary public health issues. The overdose death crisis that continues to afflict Canadian populations is not an isolated health issue. Across Canada, it is intertwined with mental health, HIV/AIDS, COVID-19 and structural violence—the chronic and systemic disadvantages affecting those living in poverty and oppressive circumstances. Opioid use is an often-avoidant coping strategy for many experiencing the effects of trauma, relentless fear, pain, ill health and social exclusion. In particular, Indigenous and non-Indigenous women’s experiences with opioid addiction are entangled with encounters with gender based-violence, poverty and chronic ailments within structurally imposed processes and stressors shaped by a history of colonialism, ruptured lifeways and Western ways of knowing and doing, leading to disproportionate harms and occurrences of illness. While biomedical models of comorbidity and mortality approach substance misuse, gender-based violence and major infectious diseases such as HIV/AIDS and COVID-19 as distinct yet compounding realities, this article argues that these conditions are synergistically interrelated via the critical/reflexive lens of syndemic frameworks. Through secondary research using academic, media and policy sources from the past decade in Canada, complemented by prior ethnographic research, the synergistic connections among opioid addiction, gender-based violence and the effects of the COVID pandemic on diverse women will be shown to be driven by socio-structural determinants of health including poverty, intergenerational trauma, the legacy of colonialism and Western optics. Together, they embody a contemporary Canadian syndemic necessitating coordinated responses. Full article

Spodoptera frugiperda (J.E. Smith) (Noctuidae: Lepidoptera) is a notable insect pest that invades major cereal crops, causing significant damage and loss. Resistances of 2nd instar larvae of two Egyptian field populations of S. frugiperda, collected from the Fayoum and Giza governments, were measured against eight insecticides, including traditional insecticides (profenofos and cypermethrin), bio-insecticides (emamectin benzoate, spinosad, and Bacillus thuringiensis), and insect growth regulators (IGRs) (lufenuron, diflubenzuron, and methoxyfenozide). In addition, the synergistic effects of three synergists (Piperonyl butoxide (PBO), diethyl maleate (DEM), and triphenyl phosphate (TPP) were assessed, and the activities of detoxification enzymes (acetylcholine esterase (AChE), cytochrome P-450 (CYP-450), carboxylesterase (CarE), and glutathione-s-transferase (GST) were also determined. Resistance surveillance revealed that the Fayoum field population showed moderate resistance to cypermethrin (RR = 5.75-fold), followed by spinosad (RR = 2.62-fold), and lufenuron (2.01-fold). On the other hand, the Giza population exhibited significant resistance to cypermethrin only (RR = 3.65-fold). Our results revealed that emamectin benzoate was the most effective insecticide, with an LC₅₀ value of 0.003 mg/L for the Fayoum population and 0.001 mg/L for the Giza population, compared to the susceptible strain (0.005 mg/L). Among the biological insecticides, Bacillus thuringiensis was the least toxic insecticide of all the tested strains. Synergism assays indicated that DEM and TPP had the most synergistic effect on spinosad (SR = 8.00-fold for both), followed by PBO (SR = 5.71-fold) for the Fayoum population, compared with spinosad alone. The assay of detoxification enzymes showed that GST activity significantly (p < 0.05) increased in the two field strains compared to the susceptible strain. However, no significant changes were observed among the tested strains in CYP-450, CarE, or AChE. The findings of this study provide substantial insights into tracking and managing the development of insecticide resistance in S. frugiperda in Egypt. Full article

The southwest coast, specifically the Khulna region of Bangladesh, has seen a substantial increase in the production of dried fish, involving marginalized coastal people. This study uses a mixed methods approach and the sustainable livelihood approach (SLA) to assess these fish-drying communities’ socioeconomic characteristics, ways of living, and adaptability. Due to their lower literacy, irregular wages, and labor-intensive employment, the research outcomes indicated that the communities engaged in the drying process were economically disadvantaged. Male workers exhibited a relatively higher participation rate compared to females. However, it was observed that females had less power over their wages and earned less than USD 2.74–3.65 per day compared to males at USD 3.65–5.48 per day. Even though there were a lot of opportunities for employment, the survey showed that very few vendors, manufacturers, and laborers regarded themselves as financially independent. To cope with various impacts and obstacles, off-season earnings, a variety of fish species, drying facilities, dealer associations, and social relationships were crucial for dried-fish processors, workers, and traders. The research suggests implementing suitable measures to diversify alternative sources of income and emphasizes the importance of fostering strong collaboration among the communities, local management authorities, and the government. With regard to dry-fish approaches, these steps are essential for ensuring long-term sustainability and improving community resilience among coastal communities. Full article

Contemporary politics is filled with anxiety about the survival of democracy—particularly within a framework pitting liberal representative democracy against authoritarianism. In times of anxiety about authoritarianism, Western artists repeatedly return to a masterpiece of relatively early cinema: Robert Weine’s silent film Das Cabinet des Dr. Caligari, or The Cabinet of Dr. Caligari. This essay examines three twenty-first century adaptations: David Lee Fisher’s 2005 remake of the film; James Morrow’s 2017 novel, The Asylum of Dr. Caligari; and Georgie Bailey’s 2022 play Caligari. I argue that while the direct politico-cultural anxieties of Weine’s film have often been overstated, the emergence of adaptations during periods of heightened concern about authoritarianism reflects a deep-seated reception of the film as anticipating autocratic governance. However, for all its fears about power, control, and the loss of self-determination, Weine’s movie also contains the seeds of liberation. Cesare ultimately sacrifices his own life rather than murdering Jane. And it is this gesture that the adaptations examined here seek—a gesture of resistance. The sleepwalker can awaken and assert a form of just resistance in the world, even if the penalties are steep. Full article

This paper presents a novel approach to optimizing the coordination between renewable energy generation enterprises and power grid companies using evolutionary game theory. The research focuses on resolving conflicts and distributing benefits between these key stakeholders in the context of large-scale renewable energy integration. A theoretical model based on replicator dynamics is developed to simulate and analyze the evolutionary stable strategies of power generation enterprises and grid companies with particular emphasis on peak shaving services and electricity bidding. These simulations are based on theoretical models and do not incorporate real-world data directly, but they aim to replicate scenarios that reflect realistic behaviors within the electricity market. The model is validated through dynamic simulation under various scenarios, demonstrating that the final strategic choices of both thermal power and renewable energy enterprises tend to evolve towards either high-price or low-price bidding strategies, significantly influenced by initial system parameters. Additionally, this study explores how the introduction of peak shaving compensation affects the coordination process and stability of renewable energy integration, providing insights into improving grid efficiency and enhancing renewable energy adoption. Although the results are simulation-based, they are designed to offer practical recommendations for grid management and policy development, particularly for the integration of renewable energies such as wind power in competitive electricity markets. The findings suggest that effective government regulation, alongside well-designed compensation mechanisms, can help establish a balanced interest distribution between stakeholders. By offering a clear framework for analyzing the dynamics of renewable energy integration, this work provides valuable policy recommendations to promote cooperation and stability in electricity markets. This study contributes to the understanding of the complex interactions in the electricity market and offers practical solutions for enhancing the integration of renewable energy into the grid. Full article

Water resources management and the broad concept of Integrated Water Resources Management (IWRM) attract varied perspectives about their effectiveness and equity as they address diverse needs across sectors and contextual situations. Managers in the water sector generally support their current governance models, while anti-poverty advocates seek more equity in the distribution of resources. Another group of stakeholders claims a lack of inclusivity in decision-making, leading to inequitable outcomes due to hegemony and colonialization of the water management domain by sector experts, officials, and other actors. IWRM focuses on reforms in water governance to achieve greater participation and sharing of power by all sectors of society in decision-making. It can facilitate the involvement of all groups of stakeholders, including those who may in some cases need to engage in social action to address water issues. This paper reviews the claims about the validity of IWRM and analyzes them according to management scenarios where water is a connector among sector issues. The scenarios show that participation in utility and local government decisions is the main pathway for urban water, wastewater, and stormwater management, while the same pathway is more difficult to organize in dispersed situations for domestic supply and irrigation in rural areas, some cases of aquifer management, and management of sprawling flood risk zones. The body of knowledge about participation in water resources management is robust, but organizational and financial capacities among existing entities pose barriers. Water resources management and IWRM do involve hegemony, and the field of practice has been colonialized, but the existential issues and complexity of the decisions and systems involved challenge society to manage successfully while assuring equity and participation through governance reform. The debates over hegemony and colonialization in water management provide an opportunity to continue improving the norms of practice and water resources education. Full article

China has entered a period of high-quality development. As an important feature of high-quality development, green total factor productivity (GTFP) has attracted much attention. With the opening-up and economic globalization, the Yangtze River Delta, one of the strongest and most technological regions in China, has been attracting an increasing amount of foreign direct investment (FDI). This study investigates if FDI is conducive to GTFP under the constraints of specific resources and a specific environment, which has important practical significance for the utilization of FDI in the Yangtze River Delta and China. Through a literature review and sorting the current FDI in the Yangtze River Delta, the GTFP and its decomposition indicators of 27 cities from 2004 to 2019 are calculated based on their energy consumption and pollution. Using the fixed-effects model and threshold model of panel data, this study tests whether FDI promotes GTFP and whether a nonlinear impact of FDI on GTFP exists. It finds that (1) the GTFP of most cities in the Yangtze River Delta improved during the sample period, but their annual growth declined. Technology is the dominant factor affecting the growth of GTFP. (2) FDI in the Yangtze River Delta has increased, and the investment structure has improved, but the distribution among cities is uneven. (3) The scale and quality of FDI have a positive impact on GTFP, which supports the “Pollution Halo” hypothesis. Economics, education, networks, and trade openness can promote the growth of GTFP, while environmental regulation, government intervention, and industrialization have a negative impact. (4) The quality of FDI, economics, the industrial structure, the environmental regulation, and the internet are each a significant single threshold characteristic for the impact of FDI on GTFP. When one of these factors is lower than a certain threshold, FDI has less impact on GTFP. When one exceeds a certain threshold, FDI’s positive promotion effect on GTFP significantly improves. Based on the analysis, this study offers some suggestions. The government should improve the FDI selection mechanism based on realities, make appropriate environmental regulatory policies, strengthen the construction of networks, and improve the “Internet+” effect on productivity. Full article

Prefabricated buildings (PBs) are considered a green way to reduce energy consumption and carbon emissions in the construction industry due to their environmental and social benefits. However, PBs have obstacles such as high construction costs, immature technology, and insufficient policy incentives, and developers’ willingness to develop them needs to be higher. Therefore, it is necessary to explore how to motivate more developers to develop PBs. In this paper, we first discuss the impact of the carbon emissions trading scheme (ETS) on the construction industry and then consider the heterogeneity of construction developers, introduce a collaborative mechanism to establish a three-party evolutionary game model between the government and the heterogeneous developers, and explore the evolution of the three-party dynamic strategies through numerical simulation. The results show that developers’ initial development probability affects the system’s evolutionary trend, and the developer who obtains more low-carbon benefits plays a dominant role. Further analyses show that critical factors such as market profitability, synergistic benefits, and carbon tax price positively influence the development of PBs, and the influence of synergistic cooperation mechanisms should be especially emphasized. This study provides practical insights into the sustainable development of the construction industry and the government’s development of a suitable carbon portfolio policy for it. Including the construction industry in the ETS is recommended when carbon prices reach 110 RMB/t. At this point, the government can remove the subsidy for PBs, but the behaviors of the developers who participate in the ETS still need to be supervised. Full article

Rapid population growth, urbanization, and diverse production materials have led to a surge in municipal solid waste (MSW), harming the environment, climate, and sanitation. Despite China’s efforts to implement MSW segregation policies, results have been unsatisfactory. Research often emphasizes public participation, with less focus on the entire policy implementation process. This paper employed Smith’s theoretical model to comprehensively analyze the challenges of implementing a MSW segregation policy, using qualitative methods and secondary data from literature and policy documents. The findings revealed challenges at four levels: policy formulation, implementing agencies, target groups, and the external environment. Issues include policy ambiguity, unclear authority, government-enterprise cross-functionality, casual attitudes, implementer shortages, poor public participation, and economic disparities. To address these, the study recommends enhancing public engagement, clarifying responsibilities among agencies, and increasing financial support for disadvantaged areas to improve policy implementation. Full article

Background: Tyrosyl-DNA phosphodiesterase 1 (Tdp1) repairs damages in DNA induced by abortive topoisomerase 1 activity; however, maintenance of genetic integrity may sustain cellular division of neoplastic cells. It follows that Tdp1-targeting chemical inhibitors could synergize well with existing chemotherapy drugs to deny cancer growth; therefore, identification of Tdp1 inhibitors may advance precision medicine in oncology. Objective: Current computational research efforts focus primarily on molecular docking simulations, though datasets involving three-dimensional molecular structures are often hard to curate and computationally expensive to store and process. We propose the use of simplified molecular input line entry system (SMILES) chemical representations to train supervised machine learning (ML) models, aiming to predict potential Tdp1 inhibitors. Methods: An open-sourced consensus dataset containing the inhibitory activity of numerous chemicals against Tdp1 was obtained from Kaggle. Various ML algorithms were trained, ranging from simple algorithms to ensemble methods and deep neural networks. For algorithms requiring numerical data, SMILES were converted to chemical descriptors using RDKit, an open-sourced Python cheminformatics library. Results: Out of 13 optimized ML models with rigorously tuned hyperparameters, the random forest model gave the best results, yielding a receiver operating characteristics-area under curve of 0.7421, testing accuracy of 0.6815, sensitivity of 0.6444, specificity of 0.7156, precision of 0.6753, and F1 score of 0.6595. Conclusions: Ensemble methods, especially the bootstrap aggregation mechanism adopted by random forest, outperformed other ML algorithms in classifying Tdp1 inhibitors from non-inhibitors using SMILES. The discovery of Tdp1 inhibitors could unlock more treatment regimens for cancer patients, allowing for therapies tailored to the patient’s condition. Full article

Urbanization is defining global change, and megacities are fast becoming a hallmark of the Anthropocene. Humanity’s pursuit toward sustainability is reliant on the successful management of these massive urban centers and their progression into sustainable and resilient settlements. Indicators and indices are applied assessment and surveillance tools used to measure, monitor, and gauge the sustainable development and urban resilience of megacities. Unknown is how indicator-based evaluations of sustainable development and urban resilience of the world’s largest 43 cities compare. In response, this review paper used the PRISMA reporting protocol, governed by 33 established and 10 emerging megacities, to compare and contrast evaluations of sustainable development and urban resilience. Results reveal that applied assessments of sustainable development of megacities appeared earlier in time and were more abundant than those of urban resilience. Geographically, China dominated other nations in affiliations to scientific research for both sustainable development and urban resilience of megacities. Among the 100 most recurrent terms, three distinct key term clusters formed for sustainable development; seven budding key term clusters formed for urban resilience suggesting breadth in contrast to sustainable development depth. The most cited assessments of sustainable development emphasize topics of energy, methodological approaches, and statistical modeling. The most cited assessments of urban resilience emphasize topics of flooding, transit networks, and disaster risk resilience. Megacities research is dominated by few countries, suggesting a need for inclusion and international partnerships. Lastly, as the world’s people become increasingly urbanized, sustainable development and urban resilience of megacities will serve as a key barometer for humanity’s progress toward sustainability. Full article

The paper presents a framework for assessing inequality in passenger rail services by examining connectivity and accessibility across two different travelframes: favorable (daytime travel) and unfavorable (nighttime travel). The unfavorable timeframe is often characterized by a lack of adequate first-/last-mile transport availability to train stations, impacting passenger access. The study employs a newly developed inequality-to-investment ratio to classify rail transport entities like stations, routes, or zones as either winners or losers, using a performance persistence analysis. A case study was conducted using data on the superfast express (SE) train schedule and investments from 2016 to 2020 across sixteen zones of the Indian Railway, assessing service inequalities during the hours of favorable (7 a.m. to 9 p.m.) and unfavorable (9 p.m. to 7 a.m.) timeframes. Results revealed inconsistencies in inequalities among zones. Moreover, the research demonstrates that the choice between connectivity and accessibility metrics significantly influences the identification of better or worse performing zones as winners or losers, respectively, throughout the 2016–2020 period and during both timeframes. The study underscores the importance of selecting appropriate measures and suggests re-evaluating or increasing investments in certain zones of Indian Railways based on these insights. The framework proposed in this paper can be used to assess inequalities within any transportation system receiving investments or government funds, contributing to the broader goal of ensuring equitable access to transportation, which is essential for a sustainable transportation system. Full article