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Search Results (20,683)

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24 pages, 711 KiB  
Review
Effects of Physical Exercise on the Microbiota in Irritable Bowel Syndrome
by Chunpeng Li, Jianmin Li, Qiaorui Zhou, Can Wang, Jiahui Hu and Chang Liu
Nutrients 2024, 16(16), 2657; https://doi.org/10.3390/nu16162657 (registering DOI) - 11 Aug 2024
Abstract
Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by abdominal pain, bloating, diarrhea, and constipation. Recent studies have underscored the significant role of the gut microbiota in the pathogenesis of IBS. Physical exercise, as a non-pharmacological intervention, has been proposed [...] Read more.
Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder characterized by abdominal pain, bloating, diarrhea, and constipation. Recent studies have underscored the significant role of the gut microbiota in the pathogenesis of IBS. Physical exercise, as a non-pharmacological intervention, has been proposed to alleviate IBS symptoms by modulating the gut microbiota. Aerobic exercise, such as running, swimming, and cycling, has been shown to enhance the diversity and abundance of beneficial gut bacteria, including Lactobacillus and Bifidobacterium. These bacteria produce short-chain fatty acids that possess anti-inflammatory properties and support gut barrier integrity. Studies involving IBS patients participating in structured aerobic exercise programs have reported significant improvements in their gut microbiota’s composition and diversity, alongside an alleviation of symptoms like abdominal pain and bloating. Additionally, exercise positively influences mental health by reducing stress and improving mood, which can further relieve IBS symptoms via the gut–brain axis. Long-term exercise interventions provide sustained benefits, maintaining the gut microbiota’s diversity and stability, supporting immune functions, and reducing systemic inflammation. However, exercise programs must be tailored to individual needs to avoid exacerbating IBS symptoms. Personalized exercise plans starting with low-to-moderate intensity and gradually increasing in intensity can maximize the benefits and minimize risks. This review examines the impact of various types and intensities of physical exercise on the gut microbiota in IBS patients, highlighting the need for further studies to explore optimal exercise protocols. Future research should include larger sample sizes, longer follow-up periods, and examine the synergistic effects of exercise and other lifestyle modifications. Integrating physical exercise into comprehensive IBS management plans can enhance symptom control and improve patients’ quality of life. Full article
(This article belongs to the Section Nutritional Immunology)
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<p>Effects of physical exercise on the gut microbiota in irritable bowel syndrome and on symptoms. IBS—irritable bowel syndrome; IS—immune system; PC—pro-inflammatory cytokines.</p>
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11 pages, 288 KiB  
Article
Virtual Reality and Higher Education Sporting Events: Social Anxiety Perception as an Outcome of VR Simulation
by Kyu-Soo Chung, Chad Goebert and John David Johnson
Behav. Sci. 2024, 14(8), 695; https://doi.org/10.3390/bs14080695 (registering DOI) - 10 Aug 2024
Viewed by 187
Abstract
Background: This study investigates the relationship between Virtual Reality Exposure Therapy (VRET) and social anxiety in sport environments. Social anxiety is a mental health condition that manifests people’s intense fear of being watched and judged by others and worrying about humiliation It is [...] Read more.
Background: This study investigates the relationship between Virtual Reality Exposure Therapy (VRET) and social anxiety in sport environments. Social anxiety is a mental health condition that manifests people’s intense fear of being watched and judged by others and worrying about humiliation It is important to research potential tools like VRET that could help to mitigate the impact of social anxiety as people with social anxiety often avoid attending live events due to the venue’s sensory stimuli and the social encounters they anticipate. VR simulation could allow socially anxious individuals to fully experience a sporting event simulation minus the anxiety induced by potential social encounters. VR’s therapeutic effects on social anxiety should be explored when considering several findings of VR intervention to mental health . Aim: The study aims to assess the impact of exposing socially anxious people to a virtual sporting game by measuring their levels of social anxiety, team identification, and intentions to attend a live sporting event before and after the VR exposure. Due to VR’s positive experience, social anxiety is expected to decrease. However, team identification and intentions to attend live sporting events are expected to increase because of VR’s ability to develop sport fanship. Method: Fourteen students with symptoms of social anxiety participated in the study. To create the VR simulation stimuli, the researchers used six 360° cameras to record an NCAA Division-I women’s volleyball game. Participants experienced the sporting event via VR simulation. Data were analyzed via one-group pre- and post-comparison. Results and Conclusion: Significant results were found for behavioral intentions of participants after experiencing the simulation. Social anxiety’s difference was negative 0.22, t(13) = 3.47, p < 0.01. After watching the game in VR, the respondents’ social anxiety decreased significantly. Team identification’s difference was 0.53, t(13) = −3.56, p < 0.01. Lastly, event visit intentions’ difference was 0.24, t(13) = −2.35, p < 0.05. Team identification and intentions to visit a sporting event rose significantly after viewing the game in VR. Full article
17 pages, 386 KiB  
Article
Strategies for Coping with Minority Stress among Queer Young Adults: Usage Frequency, Associations with Demographics, and Mental Health
by Yinuo Xu, William J. Hall, McRae Scott, Yutong Gao, Pin-Chen Chiang, Denise Yookong Williams, Ankur Srivastava, Magdelene E. Ramon and Adam R. Englert
Int. J. Environ. Res. Public Health 2024, 21(8), 1052; https://doi.org/10.3390/ijerph21081052 (registering DOI) - 10 Aug 2024
Viewed by 193
Abstract
Queer young adults report significantly higher levels of anxiety and depression than their heterosexual counterparts, which is linked to sexual minority stress. Therefore, it is important to understand the coping strategies employed by this population to navigate minority stress and how coping strategies [...] Read more.
Queer young adults report significantly higher levels of anxiety and depression than their heterosexual counterparts, which is linked to sexual minority stress. Therefore, it is important to understand the coping strategies employed by this population to navigate minority stress and how coping strategies may impact mental health outcomes. Drawing from a U.S. national diverse sample of 387 queer young adults (ages 18–39 years), we analyzed descriptive results of 11 behavioral strategies to cope with minority stress and used ordered logistic and linear regression to examine the following objectives: the frequency of the use of each coping strategy, and the associations between each strategy and demographic characteristics as well as depression and anxiety. Results revealed that avoidance and talking with friends were the most frequently utilized coping strategies, while prayer/religious activities and counseling/psychotherapy/support groups were infrequently used. We examined utilization preferences of coping strategies across demographic factors (e.g., assigned sex at birth and sexual orientation). The use of counseling/psychotherapy/support group was positively associated with mental health symptoms, while exercise and mindfulness/mediation were associated with lower mental health symptoms. Our findings provide insights for mental health researchers and professionals in selecting appropriate coping strategies for queer young adults in prevention and intervention efforts. Full article
17 pages, 1811 KiB  
Article
Thermodynamic Exercises for the Kinetically Controlled Hydrogenation of Carvone
by Artemiy A. Samarov, Sergey V. Vostrikov, Aleksandr P. Glotov and Sergey P. Verevkin
Chemistry 2024, 6(4), 706-722; https://doi.org/10.3390/chemistry6040042 (registering DOI) - 10 Aug 2024
Viewed by 107
Abstract
Carvone belongs to the chemical family of terpenoids and is the main component of various plant oils. Carvone and its hydrogenated products are used in the flavouring and food industries. A quantitative thermodynamic analysis of the general network of carvone hydrogenation reactions was [...] Read more.
Carvone belongs to the chemical family of terpenoids and is the main component of various plant oils. Carvone and its hydrogenated products are used in the flavouring and food industries. A quantitative thermodynamic analysis of the general network of carvone hydrogenation reactions was performed based on the thermochemical properties of the starting carvone and all possible intermediates and end products. The enthalpies of vaporisation, enthalpies of formation, entropies and heat capacities of the reactants were determined by complementary measurements and a combination of empirical, theoretical and quantum chemical methods. The energetics and entropy change in the hydrogenation and isomerisation reactions that take place during the conversion of carvone were derived, and the Gibbs energies of the reactions were estimated. It was shown that negative Gibbs energies are recorded for all reactions that may occur during the hydrogenation of carvone, although these differ significantly in magnitude. This means that all these reactions are thermodynamically feasible in a wide range from ambient temperature to elevated temperatures. Therefore, all these reactions definitely take place under kinetic and not thermodynamic control. Nevertheless, the numerical Gibbs energy values can help to establish the chemoselectivity of catalysts used to convert carvone to either carvacarol or to dihydro- and terahydrocarvone, either in carvotanacetone or carveol. Full article
(This article belongs to the Section Theoretical and Computational Chemistry)
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Graphical abstract

Graphical abstract
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<p>General network of carvone hydrogenation reactions.</p>
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<p>Cis-trans isomerisation of the carvone derivatives as a concomitant of carvone hydrogenation reactions.</p>
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<p>Structures of the most stable conformers of carvone (CAS 99-49-0) as calculated using the G4 method.</p>
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<p>Calculating of <math display="inline"><semantics> <mrow> <msubsup> <mrow> <mo>∆</mo> </mrow> <mrow> <mi mathvariant="normal">l</mi> </mrow> <mrow> <mi mathvariant="normal">g</mi> </mrow> </msubsup> <msubsup> <mrow> <mi>H</mi> </mrow> <mrow> <mi mathvariant="normal">m</mi> </mrow> <mrow> <mi mathvariant="normal">o</mi> </mrow> </msubsup> </mrow> </semantics></math>(298 K). Development of the contribution H→iPr(en) for the exchange of the H-atom in the cyclohexane ring for the iso-propenyl substituent (<b>left</b>). Development of the contribution H→iPr for the exchange of the H-atom in the cyclohexane ring for the iso-propyl substituent (<b>right</b>). All values in kJ·mol<sup>−1</sup>.</p>
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<p>Calculation of the enthalpy of vaporisation, <math display="inline"><semantics> <mrow> <msubsup> <mrow> <mo>∆</mo> </mrow> <mrow> <mi mathvariant="normal">l</mi> </mrow> <mrow> <mi mathvariant="normal">g</mi> </mrow> </msubsup> <msubsup> <mrow> <mi>H</mi> </mrow> <mrow> <mi mathvariant="normal">m</mi> </mrow> <mrow> <mi mathvariant="normal">o</mi> </mrow> </msubsup> </mrow> </semantics></math>(298 K), of carvone using the 2-methyl-2-cyclohexen-1-one as the “centrepiece” (<b>left</b>). Calculation the enthalpy of vaporisation, <math display="inline"><semantics> <mrow> <msubsup> <mrow> <mo>∆</mo> </mrow> <mrow> <mi mathvariant="normal">l</mi> </mrow> <mrow> <mi mathvariant="normal">g</mi> </mrow> </msubsup> <msubsup> <mrow> <mi>H</mi> </mrow> <mrow> <mi mathvariant="normal">m</mi> </mrow> <mrow> <mi mathvariant="normal">o</mi> </mrow> </msubsup> </mrow> </semantics></math>(298 K), of tetrahydrocarvone using the 2-methyl-cyclohexanone as the “centrepiece” (<b>right</b>). All values in kJ·mol<sup>−1</sup>. The experimental values of vaporisation enthalpies of the “centrepieces” are given in <a href="#app1-chemistry-06-00042" class="html-app">Tables S2 and S5</a>.</p>
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<p>Reactions of the partial and complete hydrogenation of double bonds in carvone and carvacrol (reactions 16–18 in <a href="#chemistry-06-00042-t005" class="html-table">Table 5</a>).</p>
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9 pages, 241 KiB  
Article
The Association between Anthropometric Measurements and Body Composition with Hand Grip Strength among the Elderly Population in Indonesia
by Nina Kemala Sari, Stepvia Stepvia and Muhana Fawwazy Ilyas
J. Clin. Med. 2024, 13(16), 4697; https://doi.org/10.3390/jcm13164697 (registering DOI) - 10 Aug 2024
Viewed by 184
Abstract
Background/Objectives: Hand grip strength (HGS) is a crucial measure for evaluating muscle function and general physical ability, and it may be associated with several diseases. Previous studies have demonstrated inconsistent associations between anthropometric measurement and body composition with HGS. This study aims [...] Read more.
Background/Objectives: Hand grip strength (HGS) is a crucial measure for evaluating muscle function and general physical ability, and it may be associated with several diseases. Previous studies have demonstrated inconsistent associations between anthropometric measurement and body composition with HGS. This study aims to investigate the association between anthropometric measurement and body composition with HGS in the elderly population residing in Indonesia. Methods: This is a cross-sectional study on older adults aged between 60 and 82 years who live in the community. Anthropometric parameters assessed in this study comprised the body mass index (BMI), mid-upper arm circumference (MUAC), calf circumference (CC), and waist circumference (WC). Subsequently, body composition measurements, including fat mass (FM), fat-free mass (FFM), muscle mass (MM), skeletal muscle mass (SMM), and the appendicular skeletal mass index (ASMI), were assessed using a body composition analyzer. Last, the measurement of HGS was conducted using a hand dynamometer. Results: A total of 109 participants were involved in this study. Our study demonstrates a significant association between anthropometric parameters, namely CC and HGS. Subsequently, several body composition parameters, including FFM, SMM, ASMI, and MM in the four extremities, are also significantly associated with HGS. However, in a multivariate analysis, only CC and FFM were able to significantly predict HGS. Conclusions: Improving CC and maintaining FFM may enhance muscle strength in older adults. This suggests that targeted exercise and nutrition programs could increase muscle mass and strength, thereby mitigating age-related decline and improving quality of life. Full article
(This article belongs to the Section Clinical Rehabilitation)
13 pages, 647 KiB  
Article
Isokinetic Knee Strengthening Impact on Physical and Functional Performance, Pain Tolerance, and Quality of Life in Overweight/Obese Women with Patellofemoral Pain Syndrome
by Nadhir Hammami, Eya Bouzouraa, Cengiz Ölmez, Soukaina Hattabi, Najla Mhimdi, Mehrzia Amani Khezami, Pedro Forte, Andrew Sortwell, Anissa Bouassida and Monèm Jemni
J. Clin. Med. 2024, 13(16), 4696; https://doi.org/10.3390/jcm13164696 (registering DOI) - 10 Aug 2024
Viewed by 243
Abstract
Background/Objectives: Patellofemoral syndrome is a common osteoarticular condition that affects many individuals. Various treatment options are available, with a significant emphasis on targeted muscle-strengthening exercises. The purpose of this study was to investigate the effect of isokinetic muscle strengthening on muscle strength, joint [...] Read more.
Background/Objectives: Patellofemoral syndrome is a common osteoarticular condition that affects many individuals. Various treatment options are available, with a significant emphasis on targeted muscle-strengthening exercises. The purpose of this study was to investigate the effect of isokinetic muscle strengthening on muscle strength, joint range of motion, quality of life, physical performance, and pain tolerance in overweight/obese women with patellofemoral syndrome. Methods: Twenty-four overweight or obese women with patellofemoral syndrome participated in the study during September and October 2023 in a private medical facility for physical medicine and functional rehabilitation. They were randomly assigned to one of two groups for six weeks of isokinetic muscle strengthening. The first group (ISO.G) followed a rehabilitation program combined with isokinetic muscle strengthening. A second group (PCM.G) followed a rehabilitation program that includes an isokinetic protocol in passive compensation movement. The extensors’ peak torque was measured before and after training. Results: The flexors’ peak torque, stair climbing test, 10 m walk, chair lift, monopodal support, goniometric knee flexion test, heel–buttock distance measurement, pain, and quality of life scores improved significantly in both groups. The ISO.G, on the other hand, benefited from a significant increase in quadriceps muscle strength revealed by the extensors’ peak torque. Conclusions: For the treatment of patellofemoral syndrome, isokinetic muscle strengthening in concentric mode appears to have a significant advantage over the classic rehabilitation program with isokinetic passive compensation, particularly in muscle strength gain, in addition to the improvement of joint range of motion, quality of life, physical performance, and pain tolerance. Isokinetic training may be recommended as a beneficial approach for the rehabilitative treatment of patellofemoral pain syndrome in overweight/obese women. Full article
(This article belongs to the Special Issue Obesity and Physical Exercises)
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<p>Flowchart of the study design.</p>
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12 pages, 478 KiB  
Article
Post-Isometric Relaxation Versus Self-Stretching for Non-Specific Neck Pain in Working-Age Individuals
by Vilma Dudonienė, Kornelija Mikalajūnė, Aistė Pažėrienė and Laura Žlibinaitė
Appl. Sci. 2024, 14(16), 7000; https://doi.org/10.3390/app14167000 (registering DOI) - 9 Aug 2024
Viewed by 229
Abstract
The study aimed to investigate the effectiveness of post-isometric relaxation (PIR) compared to self-stretching (SS) in working-age individuals with chronic non-specific neck pain. A parallel-group study was conducted with 50 patients who were randomized to either the self-stretching (SS, n = 25) or [...] Read more.
The study aimed to investigate the effectiveness of post-isometric relaxation (PIR) compared to self-stretching (SS) in working-age individuals with chronic non-specific neck pain. A parallel-group study was conducted with 50 patients who were randomized to either the self-stretching (SS, n = 25) or post-isometric relaxation (PIR, n = 25) group and received interventions three times a week for four weeks. In addition to these interventions, all patients were prescribed transcutaneous electrical nerve stimulation (TENS). Outcome measures were neck pain, the neck disability index (NDI), hand grip strength (HGS), and cervical spine range of motion (ROM). Data were collected at baseline and after four weeks of outpatient rehabilitation. Repeated measures ANOVA was used to determine within-group differences, and an independent t-test compared between-group differences. There were no significant differences between the groups at baseline in neck pain intensity. Following both interventions, pain intensity and functional disability decreased, cervical spine ROM increased, and HGS improved (p < 0.05). Between-group analysis showed that participants in the PIR group achieved lower pain intensity (p = 0.032, Cohen’s d = 0.81), greater neck extension ROM (p = 0.001, Cohen’s d = 0.96), and lower neck disability index (p = 0.004, Cohen’s d = 0.85) compared to the SS group. In conclusion, both PIR and SS interventions effectively reduced neck pain, increased range of motion, and decreased the neck disability index in working-age individuals. Neither technique showed superiority in increasing neck ROM and HGS. However, PIR was superior to SS in reducing neck pain and NDI, indicating potential benefits from integrating these interventions during treatment sessions. Full article
(This article belongs to the Special Issue Exercise, Fitness, Human Performance and Health)
15 pages, 971 KiB  
Article
Neglect in Older Adults: A Sociodemographic and Health Approach in the Portuguese Context
by Joana Correia Jesus, Sofia von Humboldt, Luisa Soares and Isabel Leal
Soc. Sci. 2024, 13(8), 419; https://doi.org/10.3390/socsci13080419 - 9 Aug 2024
Viewed by 216
Abstract
Southern European countries have shown indicators of accelerated aging. In Portugal, a particularly worrying aspect of this reality lies in the relationship between the aging process and the incidence of violence in older adults, as the degree of dependence and/or health status becomes [...] Read more.
Southern European countries have shown indicators of accelerated aging. In Portugal, a particularly worrying aspect of this reality lies in the relationship between the aging process and the incidence of violence in older adults, as the degree of dependence and/or health status becomes a significant risk factor for the occurrence of violence. The objectives of the present study were (1) to assess the risk of violence and indicators of neglect in Portuguese older adults; (2) to examine the differences in neglect indicators according to sociodemographic characteristics and health habits. The final sample consisted of 1012 Portuguese older adults aged 65 or over. Participants were asked about sociodemographic characteristics and health habits. The risk of violence was measured using the Vulnerability to Abuse Screening Scale, and the neglect subscale of the Elder Abuse: A Multinational Prevalence Survey was used to evaluate indicators of exposure to neglect in the past year. The results show that approximately 27% of the population presents values of risk to violence. One-tenth of participants were exposed to low levels of neglect indicators and slightly fewer people (5%) were exposed to higher levels of neglect indicators. There are significant differences regarding exposure to neglect according to the age groups, gender, and marital status, depending on the living situation, years of retirement, practice of physical exercise, existence of chronic disease, alcohol consumption, and frequency of leaving home. Full article
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<p>Descriptive data on the risk of violence (VASS) in Portuguese older adults.</p>
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<p>A summary table of the sociodemographic profile and health habits for exposure to neglect in Portuguese older adults. Note: The sociodemographic and health habit variables with significantly higher indicators of exposure to neglect are found in color.</p>
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11 pages, 12531 KiB  
Article
Effects of Exercise on the Inter-Session Accuracy of sEMG-Based Hand Gesture Recognition
by Xiangyu Liu, Chenyun Dai, Jionghui Liu and Yangyang Yuan
Bioengineering 2024, 11(8), 811; https://doi.org/10.3390/bioengineering11080811 - 9 Aug 2024
Viewed by 176
Abstract
Surface electromyography (sEMG) is commonly used as an interface in human–machine interaction systems due to their high signal-to-noise ratio and easy acquisition. It can intuitively reflect motion intentions of users, thus is widely applied in gesture recognition systems. However, wearable sEMG-based gesture recognition [...] Read more.
Surface electromyography (sEMG) is commonly used as an interface in human–machine interaction systems due to their high signal-to-noise ratio and easy acquisition. It can intuitively reflect motion intentions of users, thus is widely applied in gesture recognition systems. However, wearable sEMG-based gesture recognition systems are susceptible to changes in environmental noise, electrode placement, and physiological characteristics. This could result in significant performance degradation of the model in inter-session scenarios, bringing a poor experience to users. Currently, for noise from environmental changes and electrode shifting from wearing variety, numerous studies have proposed various data-augmentation methods and highly generalized networks to improve inter-session gesture recognition accuracy. However, few studies have considered the impact of individual physiological states. In this study, we assumed that user exercise could cause changes in muscle conditions, leading to variations in sEMG features and subsequently affecting the recognition accuracy of model. To verify our hypothesis, we collected sEMG data from 12 participants performing the same gesture tasks before and after exercise, and then used Linear Discriminant Analysis (LDA) for gesture classification. For the non-exercise group, the inter-session accuracy declined only by 2.86%, whereas that of the exercise group decreased by 13.53%. This finding proves that exercise is indeed a critical factor contributing to the decline in inter-session model performance. Full article
(This article belongs to the Section Biosignal Processing)
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Figure 1
<p>Electrode setup for the data collection. Numbers 1–4 denote the four <math display="inline"><semantics> <mrow> <mn>8</mn> <mo>×</mo> <mn>8</mn> </mrow> </semantics></math> electrode arrays placed on the forearm.</p>
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<p>Ten gestures used in the experiment: (1) wrist flexion, (2) wrist extension, (3) wrist radial, (4) wrist ulnar, (5) wrist pronation, (6) wrist supination, (7) hand close, (8) hand open, (9) thumb and index finger pinch, and (10) thumb and middle finger pinch.</p>
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<p>Two-dimensional heat map of muscle activation before and after exercise. Each map presents the RMS of sEMG signals. Brighter pixels denote more active muscle groups. For better visualization, the original <math display="inline"><semantics> <mrow> <mn>16</mn> <mo>×</mo> <mn>16</mn> </mrow> </semantics></math> maps are upsampled to <math display="inline"><semantics> <mrow> <mn>100</mn> <mo>×</mo> <mn>100</mn> </mrow> </semantics></math> via bicubic interpolation.</p>
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<p>Mean classification accuracies (%) within sessions for two groups. Statistical tests were conducted between the two groups for each session. ‘n.s.’ denotes that no statistical significance was found between exercise and non-exercise group.</p>
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<p>Mean classification accuracies (%) in the inter-session scenario for two groups. A statistical test was conducted between the two groups. ‘*’ denotes a significant difference between the two groups, with a <span class="html-italic">p</span>-value between 0.01 and 0.05.</p>
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<p>Confusion matrix for intra-session and inter-session gesture recognition. The numbers 1 to 10 represent the index of hand gestures shown in <a href="#bioengineering-11-00811-f002" class="html-fig">Figure 2</a>. Note that the value in row i and column j represents the probability that gesture i (i = 1, 2, …, 10) is recognized as gesture j (j = 1, 2, …, 10).</p>
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<p>The visualized data distribution of exercise group and non-exercise group. The bottom-right corner of the figure exhibits the centroid distances of the ten categories between two sessions for the exercise and non-exercise groups. A larger distance indicates a more significant deviation in data distribution between sessions. A <span class="html-italic">p</span>-value of less than 0.05 indicates that the data distribution deviation in the exercise group is significantly greater than that in the non-exercise group.</p>
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<p>Relationship between the increase in biceps circumference (%) and mean inter-session classification accuracy (%). Each red dot represents the mean accuracy for a specific increase in biceps circumference. The dotted line represents the fitted trend, and the shaded area indicates the confidence interval.</p>
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15 pages, 1070 KiB  
Article
Reproducibility and Repeatability in Focus: Evaluating LVEF Measurements with 3D Echocardiography by Medical Technologists
by Marc Østergaard Nielsen, Arlinda Ljoki, Bo Zerahn, Lars Thorbjørn Jensen and Bent Kristensen
Diagnostics 2024, 14(16), 1729; https://doi.org/10.3390/diagnostics14161729 - 9 Aug 2024
Viewed by 188
Abstract
Three-dimensional echocardiography (3DE) is currently the preferred method for monitoring left ventricular ejection fraction (LVEF) in cancer patients receiving potentially cardiotoxic anti-neoplastic therapy. In Denmark, however, the traditional standard for LVEF monitoring has been rooted in nuclear medicine departments utilizing equilibrium radionuclide angiography [...] Read more.
Three-dimensional echocardiography (3DE) is currently the preferred method for monitoring left ventricular ejection fraction (LVEF) in cancer patients receiving potentially cardiotoxic anti-neoplastic therapy. In Denmark, however, the traditional standard for LVEF monitoring has been rooted in nuclear medicine departments utilizing equilibrium radionuclide angiography (ERNA). Although ERNA remains a principal modality, there is an emerging trend towards the adoption of echocardiography for this purpose. Given this context, assessing the reproducibility of 3DE among non-specialized medical personnel is crucial for its clinical adoption in such departments. To assess the feasibility of 3DE for LVEF measurements by technologists, we evaluated the repeatability and reproducibility of two moderately experienced technologists. They performed 3DE on 12 volunteers over two sessions, with a collaborative review of the results from the first session before the second session. Two-way intraclass correlation values increased from 0.03 to 0.77 across the sessions. This increase in agreement was mainly due to the recognition of false low measurements. Our findings underscore the importance of incorporating reproducibility exercises in the context of 3DE, especially when operated by technologists. Additionally, routine control of the acquisitions by physicians is deemed necessary. Ensuring these hurdles are adequately managed enables the adoption of 3DE for LVEF measurements by technologists. Full article
(This article belongs to the Topic AI in Medical Imaging and Image Processing)
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<p>Boxplots of LVEF measurements by OP1 (<b>a</b>) and OP2 (<b>b</b>), further split by sex and measurement session.</p>
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<p>Strip-dot plots of LVEF percentages by OP1 (<b>a</b>) and OP2 (<b>b</b>). Triangles represent M1 and circles M2.</p>
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<p>Bland–Altman plot with LOA (solid, colored lines) with confidence intervals (shaded grey areas). Triangles represent M1 and circles M2. The x-axis represents the average LVEF of OP1 and OP2, while the y-axis represents the difference.</p>
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<p>Variability chart of the total measurement dataset generated using the “VCR” R package. Individual measurements are depicted as points, with the red plus symbol representing the mean of each replicate set. Grey horizontal bars indicate the mean of all measurements for each subject, while light-blue bars represent the means of the entire measurement session.</p>
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<p>Paired-line plots or “spaghetti-plots”, representing the change in mean-LVEF between measurement sessions for operator 1 in panel (<b>a</b>) and operator 2 in panel (<b>b</b>).</p>
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9 pages, 230 KiB  
Article
Influenza Vaccination Practices and Perceptions Among Young Athletes: A Cross-Sectional Study in Greece
by Dimitrios Lamprinos, Maria Vroulou, Michail Chatzopoulos, Panagiotis Georgakopoulos, Paraskevi Deligiorgi, Evangelos Oikonomou, Gerasimos Siasos, Petros G. Botonis, Kostas A. Papavassiliou, Dimitrios Papagiannis, Theodoros Pouletidis, Christos Damaskos, George Rachiotis and Georgios Marinos
Vaccines 2024, 12(8), 904; https://doi.org/10.3390/vaccines12080904 - 9 Aug 2024
Viewed by 340
Abstract
Background: Influenza vaccination among athletes is a crucial area in sports medicine. This descriptive, cross-sectional study aims to explore the vaccination practices and intentions regarding influenza vaccines among young athletes. Methods: A structured, questionnaire-based study was conducted among students from the National School [...] Read more.
Background: Influenza vaccination among athletes is a crucial area in sports medicine. This descriptive, cross-sectional study aims to explore the vaccination practices and intentions regarding influenza vaccines among young athletes. Methods: A structured, questionnaire-based study was conducted among students from the National School of Sports in Greece. The survey was conducted over the period of April to May 2023. Overall, 138 participants participated in the study. Results: More than half of the participants had received a flu vaccine in the past, but only 12.3% were vaccinated against influenza for 2022–2023. The main reasons seemed to be the lack of time (40.6%) and the idea that influenza does not lead to any serious health threats for the participants (36.2%). The main factor that affected their decision to get the flu vaccine or not was the need for more information regarding influenza vaccination (79%). Conclusions: The recent study showed low vaccination coverage among people of young age participating in sports activities. The qualitative views of the participants highlighted the significance of the lackof a well-organized information program provided by health professionals and coaches. Full article
(This article belongs to the Special Issue Acceptance and Hesitancy in Vaccine Uptake)
28 pages, 10501 KiB  
Article
Hydrological Monitoring System of the Navío-Quebrado Coastal Lagoon (Colombia): A Very Low-Cost, High-Value, Replicable, Semi-Participatory Solution with Preliminary Results
by Andrea Gianni Cristoforo Nardini, Jairo R. Escobar Villanueva and Jhonny I. Pérez-Montiel
Water 2024, 16(16), 2248; https://doi.org/10.3390/w16162248 - 9 Aug 2024
Viewed by 256
Abstract
Like many coastal lagoons in several countries, the “Navío Quebrado” lagoon (La Guajira, Colombia) is a very delicate and precious environment; indeed, it is a nationally recognized Flora and Fauna Sanctuary. Several factors, including climate change, are threatening its existence because of changes [...] Read more.
Like many coastal lagoons in several countries, the “Navío Quebrado” lagoon (La Guajira, Colombia) is a very delicate and precious environment; indeed, it is a nationally recognized Flora and Fauna Sanctuary. Several factors, including climate change, are threatening its existence because of changes in the governing hydro-morphological and biological processes. Certainly, the first step to addressing this problem is to understand its hydrological behavior and to be able to replicate, via simulation, its recent history before inferring likely futures. These potential futures will be marked by changes in the water input by its tributary, the Camarones River, and by modified water exchange with the sea, according to a foreseen sea level rise pattern, as well as by a different evaporation rate from the free surface, according to temperature changes. In order to achieve the required ability to simulate future scenarios, data on the actual behavior have to be gathered, i.e., a monitoring system has to be set up, which to date is non-existent. Conceptually, designing a suitable monitoring system is not a complex issue and seems easy to implement. However, the environmental, socio-cultural, and socio-economic context makes every little step a hard climb. An extremely simple—almost “primitive”—monitoring system has been set up in this case, which is based on very basic measurements of river flow velocity and water levels (river, lagoon, and sea) and the direct participation of local stakeholders, the most important of which is the National Park unit of the Sanctuary. All this may clash with the latest groovy advances of science, such as in situ automatized sensors, remote sensing, machine learning, and digital twins, and several improvements are certainly possible and desirable. However, it has a strong positive point: it provides surprisingly reasonable data and operates at almost zero additional cost. Several technical difficulties made this exercise interesting and worthy of being shared. Its novelty lies in showing how old, simple methods may offer a working solution to new challenges. This humble experience may be of help in several other similar situations across the world. Full article
(This article belongs to the Special Issue Climate Change and Hydrological Processes)
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<p>Scheme of the typical hydrological and ecological cycle of a coastal lagoon in La Guajira: (<b>a</b>) dry season; (<b>b</b>) flood season with opening of la boca and outflow of semi-fresh water; (<b>c</b>) sea–lagoon exchange according to the tide.</p>
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<p>Navío-Quebrado (Camarones) lagoon: (<b>a</b>) wet season; (<b>b</b>) opening of the mouth (“la boca”); (<b>c</b>) the bar between the sea and lagoon (closed mouth).</p>
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<p>Study area: (<b>a</b>) general location; (<b>b</b>) location of specific points of interest.</p>
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<p>Location of hydrometers: (<b>a</b>) view from downstream at Puente Troncal; (<b>b</b>) view from the observation point at Puente Viejo; (<b>c</b>) rule at Puente Troncal; (<b>d</b>) rule at the same site during a flood (this is located on the opposite side of the pillar).</p>
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<p>Cross-section at Puente Troncal. It can be noted that the 0 of the hydrometer (on the right) was placed where the water was on the day of installation; however, the water level can be lower (the depth was estimated by directly wading into the section). This means that negative values of the water height h are also possible. The wetted topography was manually surveyed by measuring depth with respect to the water surface every 100 cm, as represented in the figure.</p>
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<p>Difficult Access to the measurement sites: (<b>a</b>) Puente Troncal; (<b>b</b>) Puente Viejo.</p>
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<p>Stage–discharge relationship (polynomial regression) of the Tomarrazon-Camarones River in Puente Troncal with gauging data from 23 April 2022 until 23 October 2023 (y denotes elevation m asl).</p>
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<p>Analytic relationships (approximated) for the cross-section of the river at P.Troncal: (<b>a</b>) wetted area A = A(h); (<b>b</b>) wetted perimeter p = p(h).</p>
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<p>Matching between measured Q and Q estimated via the Chezy–Manning equation (R<sup>2</sup> = 0.9738), with data from 23 April 2022–23 October 2023.</p>
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<p>Surprise from new data on the Tomarrazon-Camarones River in Puente Troncal: (<b>a</b>) Stage–discharge relationship (power law regression, R<sup>2</sup> = 0.9172) with gauging data from 23 April 2022 until 23 November 2023; (<b>b</b>) matching between measured and estimated values (red line: perfect matching, dotted line: linear regression with R<sup>2</sup> = 0.9119).</p>
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<p>Deviation Q measured vs. Q estimated by the found stage–discharge relationship (m<sup>3</sup>/<sub>s</sub>) as a function of the water elevation y<sub>Lagoon</sub> (in cm above sea level). The blue dotted line interpolates the points linearly.</p>
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<p>Improvement of the matching between measured Q and Q estimated by the Q = Q(y<sub>river</sub>, y<sub>lagoon</sub>) relationship (light blue dots are the same as in <a href="#water-16-02248-f009" class="html-fig">Figure 9</a> for ease of comparison). Data until 23 November 2023.</p>
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<p>Extract of the time series of recorded data (at hourly time steps) showing the inconsistency between lagoon data and sea data, which are always higher than 0 and higher than the lagoon levels (top: sea elevation data kindly provided by DIMAR: daily moving average indicated by the darker line; bottom: lagoon water elevation data collected by our project).</p>
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<p>General view of the lagoon water level measurement system.</p>
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<p>Construction details of the water surface measurement system: (<b>a</b>) sealed inlet of the hydrometer; (<b>b</b>) filtering lateral surface of the piezometer covered by a plastic grid and inserted into gravel-filled holes; (<b>c</b>) fully installed system.</p>
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<p>Scheme of the construction details of the measuring systems: (<b>a</b>) hydrometer and (<b>b</b>) piezometer.</p>
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<p>Alteration of the measurement of the water level h because of the volume of the inserted rule.</p>
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<p>“Instantaneous altimetry” criterion: Elevation pattern of lagoon perimeter according to satellite images taken in 2017 (basis of the adopted DEM). The local peaks (“outliers”) are attributed to DEM imperfections, possibly due to imprecision in the definition of the water surface polygon which may create incorrect height values. What counts here, anyway, is the prevailing behavior. The mean elevation is denoted by the brown bar.</p>
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<p>Horizontality check: synchronic monitoring criterion: (<b>a</b>) original data obtained; (<b>b</b>) the three sets of curves refer to three different survey days (in May, no exchange with the sea or river inflow and negligible evaporation effect during daytime, so constant values; in June, outgoing flow is emptying the lagoon, although a moderate river inflow was present; in November a significant river inflow is filling the lagoon, in spite of a moderate open mouth); the top curves refer to the lagoon, the bottom ones to the river at the same time: a synchronic behavior is apparent, as well as the existence of an elevation difference of about 12–20 cm.</p>
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<p>Instantaneous altimetry test based on DEM analysis: Shore affected by lower (<b>a</b>) and higher (<b>b</b>) elevations; location of anomalous points: the most depressed point (y= −1 m.a.s.l) corresponds to the boca and was most probably captured near the surface of the sea; the highest one, on the other hand, lies in the middle of nowhere and seems to be a local imperfection.</p>
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<p>Details of the mouth and velocity measurements: (<b>a</b>) lagoon during an “open period”; (<b>b</b>) Our vehicle for surveying the cross-section; (<b>c</b>) Manual measurement of depth and velocity.</p>
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<p>Spatial pattern of 111 GNSS-RTK points (red). The background image is a Landsat 8 of 20 September 2022 when the lagoon was at maximum filling. The false color image identifies water (dark blue tone) under a combination of bands: NIR, SWIR1, and Red.</p>
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<p>Hypsometric curves: Surface area S = S(y) (m<sup>2</sup>); Storage volume V= V(y) (m<sup>3</sup>) related to lagoon elevation y<sub>L</sub> [masl]. Polynomial curves: S(y) = 8010914.35 y<sup>3</sup> − 8335673.88 y<sup>2</sup> + 7166288.16 y + 16056191.36 (R<sup>2</sup> = 1.00); V(y) = 4983114.71 y<sup>2</sup> + 15272088.13 y + 8414661.47 (R<sup>2</sup> = 1.00).</p>
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<p>Climatological variables of the study area (from IDEAM data: Rain from Camarones station ID 15050010. All others from Riohacha station ID 15065180).</p>
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<p>Output of the monitoring system for the period of 10 December 2021 to 14 January 2023 (hourly time step; one square is 500 h), with no correction for the sea level data. At the bottom is the status of the lagoon mouth: C: closed; O: Open; S: Semi-open.</p>
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<p>Summary of the whole exercise conducted to set up the hydrological monitoring system.</p>
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14 pages, 2489 KiB  
Article
The Influence of Acute Oral Lactate Supplementation on Responses to Cycle Ergometer Exercise: A Randomized, Crossover Pilot Clinical Trial
by Taylor R. Ewell, Matthew C. Bomar, David M. Brown, Reagan L. Brown, Beatrice S. Kwarteng, David P. Thomson and Christopher Bell
Nutrients 2024, 16(16), 2624; https://doi.org/10.3390/nu16162624 - 9 Aug 2024
Viewed by 355
Abstract
The purpose of this study was to investigate the potential ergogenic effects of an oral lactate supplement. For this double-blind, randomized, placebo-controlled crossover design, fifteen recreational exercisers (nine males, six females) ingested a placebo or a commercially available lactate supplement prior to cycle [...] Read more.
The purpose of this study was to investigate the potential ergogenic effects of an oral lactate supplement. For this double-blind, randomized, placebo-controlled crossover design, fifteen recreational exercisers (nine males, six females) ingested a placebo or a commercially available lactate supplement prior to cycle ergometer exercise. Primary outcomes included peak oxygen uptake (VO2peak; via indirect calorimetry), VO2 at the ventilatory threshold, and work rate at the lactate threshold (arterialized venous blood from a heated hand) determined during incremental exercise to fatigue, and power output during a 20-min cycling time trial. Compared with placebo, the oral lactate supplement (19 ± 1 mg/kg body mass) did not influence VO2peak (placebo: 44.3 ± 7.8 vs. oral lactate: 44.3 ± 7.1 mL/kg/min (mean ± SD); p = 0.87), VO2 at the ventilatory threshold (placebo: 1.63 ± 0.25 vs. oral lactate: 1.65 ± 0.23 L/min; p = 0.82), or work rate at the lactate threshold (placebo: 179 ± 69 vs. oral lactate: 179 ± 59 W; p = 0.41). Throughout the 20-min time trial, the work rate was slightly greater (4%) with oral lactate (204 ± 41 W) compared with placebo (197 ± 41 W; main effect of treatment p = 0.02). Collectively, these data suggest that this commercially available lactate supplement did not acutely influence the physiological responses to incremental cycle ergometer exercise but elicited a modest ergogenic effect during the short-duration time trial. Full article
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<p>Consolidated standards of reporting trials (CONSORT) flow diagram for incremental exercise test.</p>
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<p>Consolidated standards of reporting trials (CONSORT) flow diagram for FTP<sup>20</sup>.</p>
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<p>Oral lactate had no influence on the physiological responses to ramp exercise. Panels (<b>A</b>–<b>E</b>): The paired mean difference between placebo and oral lactate as illustrated using estimation plots. Both conditions are plotted on the left axes as a slopegraph: each paired set of observations is connected by a line. The paired mean difference is plotted on a floating axis on the right. Symbols represent individual mean differences, the horizontal line at zero provides reference, the other shows the actual mean difference. The error bars around the heavy solid horizontal line are the 95% confidence intervals. Panel (<b>A</b>): Oral lactate had no influence on peak oxygen uptake (VO<sub>2peak</sub>). Panel (<b>B</b>): Oral lactate had no influence on work rate at VO<sub>2peak</sub>. Panel (<b>C</b>): Oral lactate had no influence on heart rate at VO<sub>2peak</sub>. Panel (<b>D</b>): Oral lactate had no influence on respiratory exchange ratio (RER) at VO<sub>2peak</sub>. Panel (<b>E</b>): Oral lactate had no influence on the VO<sub>2</sub> at ventilatory threshold. Panel (<b>F</b>): Oral lactate had no influence on blood lactate concentration during incremental exercise. Panels (<b>A</b>–<b>E</b>) show individual data, discriminated by sex. Panel (<b>F</b>) shows mean and standard deviation of group data. Exercise time was normalized to % of time to exhaustion to promote visual clarity.</p>
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<p>Oral lactate evoked a modest improvement in 20-min cycle ergometer time trial performance without influencing heart rate or ratings of perceived exertion (RPE). Panels (<b>A</b>,<b>B</b>) show group (<b>A</b>) and individual (<b>B</b>) data for work rates over the 20-min trial. Panel (<b>C</b>): Oral lactate had no influence on heart rate during the time trial. Panel (<b>D</b>): Oral lactate had no influence on RPE during the time trial. Panels (<b>A</b>,<b>C</b>,<b>D</b>) show mean and standard deviation of group data. Panel (<b>B</b>) shows individual responses; data have been offset from 5-min markers to promote visual clarity.</p>
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11 pages, 391 KiB  
Article
Match Injury Incidence for a New Zealand Amateur Domestic Female Soccer Team over Two Consecutive Seasons
by Doug A. King, Patria A. Hume and Trevor N. Clark
Sports 2024, 12(8), 216; https://doi.org/10.3390/sports12080216 - 9 Aug 2024
Viewed by 161
Abstract
Objective: To determine the match injury incidence for a New Zealand amateur domestic female soccer team over two consecutive seasons. Methods: A descriptive, epidemiological observational study was conducted to determine match injury incidence for 49 players over two domestic seasons. Match exposure and [...] Read more.
Objective: To determine the match injury incidence for a New Zealand amateur domestic female soccer team over two consecutive seasons. Methods: A descriptive, epidemiological observational study was conducted to determine match injury incidence for 49 players over two domestic seasons. Match exposure and injury burden were calculated. Results: A total of 84 match-related injuries resulted in a match injury incidence of 145.5 (95% confidence interval (CI): 117.4 to 180.1) per 1000 match h. Attackers had a higher incidence of injuries for total (200.0 per 1000 match h) and missed matches (152.4 per 1000 match h). The lower limbs had the highest injury incidence (105.6 per 1000 match h), with ankle injury being the most reported (43.3 per 1000 match h) lower limb injury. Over three quarters (75.3%) of the injuries recorded were missed match injuries. Sprains/strains were the most recorded total (86.6 per 1000 match h) injury type. Fractures were recorded as having the highest mean injury burden (68.7 ± 70.4 days). Discussion: Historically, there was a paucity of injury burden data for female football; however, the data presented within this study can be utilised to support the identification of injury patterns and areas to be included within injury reduction programmes. Full article
16 pages, 5072 KiB  
Article
Design of Exergaming Platform for Upper Limb Rehabilitation Using Surface Electromyography
by Nikolaos Panagiotopoulos, Sofia Lampropoulou, Nikolaos Avouris and Athanassios Skodras
Appl. Sci. 2024, 14(16), 6987; https://doi.org/10.3390/app14166987 - 9 Aug 2024
Viewed by 220
Abstract
This study explores the development and pilot testing of an exergame designed for the rehabilitation of individuals with upper limb deficits. While traditional physiotherapy is effective, it often fails to fully engage patients due to its repetitive nature. This research integrates a novel [...] Read more.
This study explores the development and pilot testing of an exergame designed for the rehabilitation of individuals with upper limb deficits. While traditional physiotherapy is effective, it often fails to fully engage patients due to its repetitive nature. This research integrates a novel exergame into physiotherapy regimens, aiming to enhance patient motivation through a gaming experience that complements conventional sessions. The exergame is structured around a narrative-driven adventure, with exercises embedded in gameplay that mirror adjustable physiotherapy routines. It utilizes the Myo armband, a wearable electromyography device, to capture muscle activity and movement. The system, part of a web-based platform, is easily deployable in various settings, including home environments. Comprehensive evaluations with health professionals and neurological patients indicate that the exergame significantly improves patient engagement. This study not only demonstrates the potential of exergames in enhancing traditional therapy but also underscores the importance of patient-centered therapeutic tools. Full article
(This article belongs to the Section Biomedical Engineering)
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<p>Architecture of the exergaming platform.</p>
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<p>Screenshots illustrating the storytelling elements of the game. (<b>a</b>) Title screen. (<b>b</b>) Frame from the introductory scene. (<b>c</b>) Home screen for the first week. (<b>d</b>) Home screen for the fourth week.</p>
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<p>Gameplay scene showing key elements numbered for reference.</p>
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<p>Images capturing various stages of the gameplay. (<b>a</b>) During the hold time of the exercise. (<b>b</b>) Just after the hold time has passed but before the player stops the exercise. (<b>c</b>) During the rest time of the exercise. (<b>d</b>) Just before level completion.</p>
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<p>Example of incorrect movement recognition in the game. While the game screenshot on the left shows a successfully completed finger abduction repetition, the attached camera footage on the right reveals the player performing a finger flexion motion at that moment.</p>
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<p>Mean scores based on Likert scale.</p>
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<p>Mean level completion times (in minutes) for each member of the respective groups.</p>
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<p>Successful recognition rate comparison.</p>
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