Search Results (32,604)

The HIFU ablation technique is limited by the long duration of the procedure, which results from the large difference between the size of the HIFU beam’s focus and the tumor size. Ablation of large tumors requires treating them with a sequence of single HIFU beams, with a specific time interval in-between. The aim of this study was to evaluate the biological effects induced in a malignant solid tumor of the rat mammary gland, implanted in adult Wistar rats, during HIFU treatment according to a new ablation plan which allowed researchers to significantly shorten the duration of the procedure. We used a custom, automated, ultrasound imaging-guided HIFU ablation device. Tumors with a 1 mm thickness margin of healthy tissue were subjected to HIFU. Three days later, the animals were sacrificed, and the HIFU-treated tissues were harvested. The biological effects were studied, employing morphological, histological, immunohistochemical, and ultrastructural techniques. Massive cell death, hemorrhages, tissue loss, influx of immune cells, and induction of pro-inflammatory cytokines were observed in the HIFU-treated tumors. No damage to healthy tissues was observed in the area surrounding the safety margin. These results confirmed the efficacy of the proposed shortened duration of the HIFU ablation procedure and its potential for the treatment of solid tumors. Full article

In the Energy-Harvesting (EH) Cognitive Internet of Things (EH-CIoT) network, due to the broadcast nature of wireless communication, the EH-CIoT network is susceptible to jamming attacks, which leads to a serious decrease in throughput. Therefore, this paper investigates an anti-jamming resource-allocation method, aiming to maximize the Long-Term Throughput (LTT) of the EH-CIoT network. Specifically, the resource-allocation problem is modeled as a Markov Decision Process (MDP) without prior knowledge. On this basis, this paper carefully designs a two-dimensional reward function that includes throughput and energy rewards. On the one hand, the Agent Base Station (ABS) intuitively evaluates the effectiveness of its actions through throughput rewards to maximize the LTT. On the other hand, considering the EH characteristics and battery capacity limitations, this paper proposes energy rewards to guide the ABS to reasonably allocate channels for Secondary Users (SUs) with insufficient power to harvest more energy for transmission, which can indirectly improve the LTT. In the case where the activity states of Primary Users (PUs), channel information and the jamming strategies of the jammer are not available in advance, this paper proposes a Linearly Weighted Deep Deterministic Policy Gradient (LWDDPG) algorithm to maximize the LTT. The LWDDPG is extended from DDPG to adapt to the design of the two-dimensional reward function, which enables the ABS to reasonably allocate transmission channels, continuous power and work modes to the SUs, and to let the SUs not only transmit on unjammed channels, but also harvest more RF energy to supplement the battery power. Finally, the simulation results demonstrate the validity and superiority of the proposed method compared with traditional methods under multiple jamming attacks. Full article

Large language models (LLMs), designed to provide helpful and safe responses, often rely on alignment techniques to align with user intent and social guidelines. Unfortunately, this alignment can be exploited by malicious actors seeking to manipulate an LLM’s outputs for unintended purposes. In this paper, we introduce a novel approach that employs a genetic algorithm (GA) to manipulate LLMs when model architecture and parameters are inaccessible. The GA attack works by optimizing a universal adversarial prompt that—when combined with a user’s query—disrupts the attacked model’s alignment, resulting in unintended and potentially harmful outputs. Our novel approach systematically reveals a model’s limitations and vulnerabilities by uncovering instances where its responses deviate from expected behavior. Through extensive experiments, we demonstrate the efficacy of our technique, thus contributing to the ongoing discussion on responsible AI development by providing a diagnostic tool for evaluating and enhancing alignment of LLMs with human intent. To our knowledge, this is the first automated universal black-box jailbreak attack. Full article

In precise space operation tasks, the impact of disturbing torques on the space flexible robotic arm (SFRA) cannot be ignored. Besides, the slender structure of the SFRA is very likely to generate vibration of the robotic arm. These are all potential hidden dangers in space safety. To quantify the potential risk, an accurate dynamics model of the SFRA considering the disturbing torque is built by Lagrange principle and the assumed modal method (AMM). Moreover, the effects of the disturbing torque, modal order and nonlinear terms on the deformation accuracy of the SFRA are compared. It is observed that the simplified dynamics model with neglecting the nonlinear terms (NNTs) has a high model accuracy and be easily solved. Therefore, the NNTs simplified model is chosen for deriving the transfer function of the SFRA. The parameters of the PI controller are adjusted in real time based on fuzzy rules to reduce the tracking error in the SFRA. In addition, the disturbance observer is designed to observe and compensate of the disturbance torque in the SFRA. The control method of adjusting controller parameters with fuzzy rules based on the disturbance observer greatly improves the rotational control accuracy of the SFRA. Finally, the validity of aforementioned control strategy is confirmed by simulation analysis and experimental results. Full article

To address the issue of automated apple harvesting in orchards, we propose a YOLOv5-RACF algorithm for identifying apples and calculating apple diameters. This algorithm employs the robot operating dystem (ROS) to control the robot’s locomotion system, Lidar mapping, and navigation, as well as the robotic arm’s posture and grasping operations, achieving automated apple harvesting and placement. The tests were conducted in an actual orchard environment. The algorithm model achieved an average apple detection accuracy ([email protected]) of 98.748% and a ([email protected]:0.95) of 90.02%. The time to calculate the diameter of one apple was 0.13 s, with a measurement accuracy within an error range of 1–3 mm. The robot takes an average of 9 s to pick an apple and return to the initial pose. These results demonstrate the system’s efficiency and reliability in real agricultural environments. Full article

High-altitude acclimatization refers to the physiological adjustments and adaptation processes by which the human body gradually adapts to the hypoxic conditions of high altitudes after entering such environments. This study analyzed three mRNA expression profile datasets from the GEO database, focusing on 93 healthy residents from low altitudes (≤1400 m). Peripheral blood samples were collected for analysis on the third day after these individuals rapidly ascended to higher altitudes (3000–5300 m). The analysis identified significant differential expression in 382 genes, with 361 genes upregulated and 21 downregulated. Further, gene ontology (GO) annotation analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis indicated that the top-ranked enriched pathways are upregulated, involving blood gas transport, erythrocyte development and differentiation, and heme biosynthetic process. Network analysis highlighted ten key genes, namely, SLC4A1, FECH, EPB42, SNCA, GATA1, KLF1, GYPB, ALAS2, DMTN, and GYPA. Analysis revealed that two of these key genes, FECH and ALAS2, play a critical role in the heme biosynthetic process, which is pivotal in the development and maturation of red blood cells. These findings provide new insights into the key gene mechanisms of high-altitude acclimatization and identify potential biomarkers and targets for personalized acclimatization strategies. Full article

The phonocardiogram (PCG) is a crucial tool for the early detection, continuous monitoring, accurate diagnosis, and efficient management of cardiovascular diseases. It has the potential to revolutionize cardiovascular care and improve patient outcomes. The PhysioNet/CinC Challenge 2016 database, a large and influential resource, encourages contributions to accurate heart sound state classification (normal versus abnormal), achieving promising benchmark performance (accuracy: 99.80%; sensitivity: 99.70%; specificity: 99.10%; and score: 99.40%). This study reviews recent advances in analytical techniques applied to this database, and 104 publications on PCG signal analysis are retrieved. These techniques encompass heart sound preprocessing, signal segmentation, feature extraction, and heart sound state classification. Specifically, this study summarizes methods such as signal filtering and denoising; heart sound segmentation using hidden Markov models and machine learning; feature extraction in the time, frequency, and time-frequency domains; and state-of-the-art heart sound state recognition techniques. Additionally, it discusses electrocardiogram (ECG) feature extraction and joint PCG and ECG heart sound state recognition. Despite significant technical progress, challenges remain in large-scale high-quality data collection, model interpretability, and generalizability. Future directions include multi-modal signal fusion, standardization and validation, automated interpretation for decision support, real-time monitoring, and longitudinal data analysis. Continued exploration and innovation in heart sound signal analysis are essential for advancing cardiac care, improving patient outcomes, and enhancing user trust and acceptance. Full article

Expandable graphite (EG) was modified with a charring agent and organic–inorganic hybridized intumescent flame retardants (MEG) were synthesized. This study uses a cone calorimeter (CCT) and a DaqPRO 5300 radiation heat flow meter (Fourtec, Tel Aviv, Israel) to evaluate the fire-resistant properties influenced by MEG on intumescent fire-retardant coatings. The impact of MEG on the thermal degradation of these coatings was investigated through the use of thermogravimetric analysis (TGA). The results obtained by CCT demonstrated that the incorporation of MEG markedly diminished the heat release rate and total heat release rate of the coating, in addition to enhancing the char residue compared to coatings with only expandable graphite (EG). Furthermore, TGA results demonstrate that adding MEG increases the weight of the char residue at elevated temperatures, suggesting improved thermal stability. Based on these findings, MEG exhibits a synergistic flame-retardant effect when combined with intumescent fire-retardant (IFR) systems. This synergy not only improves the flame-retardant properties of the coatings but also enhances their overall thermal stability, making MEG a promising additive for developing more efficient fire-retardant materials. Thus, MEG-modified coatings offer superior protection against fire hazards, highlighting their potential for practical applications in fire safety. Full article

The Sentinel-2 NDVI time series information content from 2017 to 2023 at a 10 m spatial resolution was evaluated based on the NDVI temporal dependency in five scenarios in central Spain. First, time series were interpolated and then filtered using the Savitzky–Golay, Fast Fourier Transform, Whittaker, and Maximum Value filters. Temporal dependency was assessed using the Q-Ljung-Box and Fisher’s Kappa tests, and similarity between raw and filtered time series was assessed using Correlation Coefficient and Root Mean Square Error. An Interpolating Efficiency Indicator (IEI) was proposed to summarize the number and temporal distribution of low-quality observations. Type of climate, atmospheric disturbances, land cover dynamics, and management were the main sources of variability in five scenarios: (1) rainfed wheat and barley presented high short-term variability due to clouds (lower IEI in winter and spring) during the growing cycle and high interannual variability due to precipitation; (2) maize showed stable summer cycles (high IEI) and low interannual variability due to irrigation; (3) irrigated alfalfa was cut five to six times during summer, resulting in specific intra-annual variability; (4) beech forest showed a strong and stable summer cycle, despite the short-term variability due to clouds (low IEI); and (5) evergreen pine forest had a highly variable growing cycle due to fast responses to temperature and precipitation through the year and medium IEI values. Interpolation after removing non-valid observations resulted in an increase in temporal dependency (Q-test), particularly a short term in areas with low IEI values. The information improvement made it possible to identify hidden periodicities and trends using the Fisher’s Kappa test. The SG filter showed high similarity values and weak influence on dynamics, while the MVF showed an overestimation of the NDVI values. Full article

Effective construction project planning relies on addressing constraints related to materials, labor, equipment, and others. Planning meetings are typical venues for stakeholders to identify, communicate, and remove constraints. However, a critical gap exists in lacking an automated approach to identify, classify, analyze, and track constraint discussions during onsite planning meetings. Therefore, this research aims to 1. develop a natural language processing model to classify constraints in meeting discussions; 2. uncover the discussion patterns of managers and foremen regarding various constraints; and 3. extract the root causes for constraints, evaluate their impacts, and prepare managers to develop practical solutions for constraint removal. This research collected meeting transcripts from 94 onsite planning meetings of a building project, spanning 263,836 words. Next, this research leveraged a general pretrained transformer (GPT) to segment discussion dialogs into topics. A Bidirectional Encoder Representations from Transformers (BERT)-based model was developed to categorize constraint types for each topic. The constraint patterns among meeting attendees were assessed. Furthermore, a GPT-based tool was devised to track root causes, impacts, and solutions for various constraints. Test results revealed an 8.8% improvement in constraint classification accuracy compared with the traditional classification model. An occupational characteristic in constraint discussion was observed in that the management team tended to balance their focus on various constraints, while foremen concentrated on more practical issues. This research contributes to the body of knowledge by leveraging language models to analyze construction planning meetings. The findings facilitate project managers in establishing constraint logs for diagnosing and prognosticating planning issues. Full article

Recently, an affine-projection-like M-estimate (APLM) algorithm has gained popularity for its ability to effectively handle impulsive background disturbances. Nevertheless, the APLM algorithm’s performance is negatively affected by steady-state misalignment. To address this issue while maintaining equivalent computational complexity, a robust cost function based on the Andrew’s sine estimator (ASE) is introduced and a corresponding affine-projection Andrew’s sine estimator (APASE) algorithm is proposed in this paper. To further enhance the tracking capability and accelerate the convergence rate, we develop the combined-step-size APASE (CSS-APASE) algorithm using a combination of two different step sizes. A series of simulation studies are conducted in system identification and echo cancellation scenarios, which confirms that the proposed algorithms can attain reduced misalignment compared to other currently available algorithms in cases of impulsive noise. Meanwhile, we also establish a bound on the learning rate to ensure the stability of the proposed algorithms. Full article

The series-type 12-pulse rectifier generates a large amount of harmonics in the AC side current due to the strong nonlinearity of its rectifying diodes, causing serious harmonic pollution to the power grid. This article proposes a series 36-pulse rectifier based on a DC side dual passive frequency-doubling circuit to suppress the AC side current harmonics of a 12-pulse rectifier. The rectifier uses two symmetrical passive pulse multiplication circuits to regulate the circulation in the DC side circuit, increasing the output voltage and current state of the rectifier bridge, thereby increasing the number of pulses in the rectifier from 12 times to 36 times. Firstly, the working principle of the rectifier and the working mode of the dual passive frequency-doubling circuit were analyzed. Secondly, the harmonic suppression mechanism of the rectifier input current was revealed, and the frequency-doubling characteristics of the load voltage were analyzed. Finally, the correctness of the theoretical analysis was verified through a semi-physical platform. The verification and comparison results show that under the optimal conditions of the injecting transformer turns ratio, the DPPC can not only reduce the THD value of the input current by about 1/3 (from 14.87% to 4.78%) but can also increase the fluctuation frequency of the load voltage by 3 times (from 12 to 36), while improving the power quality of the AC/DC side rectifier and achieving the low harmonic operation of the rectifier. The proposed 36-pulse rectifier can effectively suppress harmonics; it has the advantages of simple structure, strong robustness, and high output voltage gain, and it is suitable for medium-voltage and high-voltage high-power rectification applications. Full article

Distracted driving is one of the major factors leading drivers to ignore potential road hazards. In response to the challenges of high computational complexity, limited generalization capacity, and suboptimal detection accuracy in existing deep learning-based detection algorithms, this paper introduces a novel approach called StarDL-YOLO (StarNet-detectlscd-yolo), which leverages an enhanced version of YOLOv8n. Initially, the StarNet integrated into the backbone of YOLOv8n significantly improves the feature extraction capability of the model with remarkable reduction in computational complexity. Subsequently, the Star Block is incorporated into the neck network, forming a C2f-Star module that offers lower computational cost. Additionally, shared convolution is introduced in the detection head to further reduce computational burden and parameter size. Finally, the Wise-Focaler-MPDIoU loss function is proposed to strengthen detection accuracy. The experimental results demonstrate that StarDL-YOLO significantly improves the efficiency of the distracted driving behavior detection, achieving an accuracy of 99.6% on the StateFarm dataset. Moreover, the parameter count of the model is minimized by 56.4%, and its computational load is decreased by 45.1%. Additionally, generalization experiments are performed on the 100-Driver dataset, revealing that the proposed scheme enhances generalization effectiveness compared to YOLOv8n. Therefore, this algorithm significantly reduces computational load while maintaining high reliability and generalization capability. Full article

Historical handwritten manuscripts pose challenges to automated recognition techniques due to their unique handwriting styles and cultural backgrounds. In order to solve the problems of complex text word misdetection, omission, and insufficient detection of wide-pitch curved text, this study proposes a high-precision text detection method based on improved YOLOv8s. Firstly, the Swin Transformer is used to replace C2f at the end of the backbone network to solve the shortcomings of fine-grained information loss and insufficient learning features in text word detection. Secondly, the Dysample (Dynamic Upsampling Operator) method is used to retain more detailed features of the target and overcome the shortcomings of information loss in traditional upsampling to realize the text detection task for dense targets. Then, the LSK (Large Selective Kernel) module is added to the detection head to dynamically adjust the feature extraction receptive field, which solves the cases of extreme aspect ratio words, unfocused small text, and complex shape text in text detection. Finally, in order to overcome the CIOU (Complete Intersection Over Union) loss in target box regression with unclear aspect ratio, insensitive to size change, and insufficient correlation between target coordinates, Gaussian Wasserstein Distance (GWD) is introduced to modify the regression loss to measure the similarity between the two bounding boxes in order to obtain high-quality bounding boxes. Compared with the State-of-the-Art methods, the proposed method achieves optimal performance in text detection, with the precision and [email protected] reaching 86.3% and 82.4%, which are 8.1% and 6.7% higher than the original method, respectively. The advancement of each module is verified by ablation experiments. The experimental results show that the method proposed in this study can effectively realize complex text detection and provide a powerful technical means for historical manuscript reproduction. Full article

Accurate and reliable PV power probabilistic-forecasting results can help grid operators and market participants better understand and cope with PV energy volatility and uncertainty and improve the efficiency of energy dispatch and operation, which plays an important role in application scenarios such as power market trading, risk management, and grid scheduling. In this paper, an innovative deep learning quantile regression ultra-short-term PV power-forecasting method is proposed. This method employs a two-branch deep learning architecture to forecast the conditional quantile of PV power; one branch is a QR-based stacked conventional convolutional neural network (QR_CNN), and the other is a QR-based temporal convolutional network (QR_TCN). The stacked CNN is used to focus on learning short-term local dependencies in PV power sequences, and the TCN is used to learn long-term temporal constraints between multi-feature data. These two branches extract different features from input data with different prior knowledge. By jointly training the two branches, the model is able to learn the probability distribution of PV power and obtain discrete conditional quantile forecasts of PV power in the ultra-short term. Then, based on these conditional quantile forecasts, a kernel density estimation method is used to estimate the PV power probability density function. The proposed method innovatively employs two ways of a priori knowledge injection: constructing a differential sequence of historical power as an input feature to provide more information about the ultrashort-term dynamics of the PV power and, at the same time, dividing it, together with all the other features, into two sets of inputs that contain different a priori features according to the demand of the forecasting task; and the dual-branching model architecture is designed to deeply match the data of the two sets of input features to the corresponding branching model computational mechanisms. The two a priori knowledge injection methods provide more effective features for the model and improve the forecasting performance and understandability of the model. The performance of the proposed model in point forecasting, interval forecasting, and probabilistic forecasting is comprehensively evaluated through the case of a real PV plant. The experimental results show that the proposed model performs well on the task of ultra-short-term PV power probabilistic forecasting and outperforms other state-of-the-art deep learning models in the field combined with QR. The proposed method in this paper can provide technical support for application scenarios such as energy scheduling, market trading, and risk management on the ultra-short-term time scale of the power system. Full article