Search Results (2,783)

Maturity-onset diabetes of the young (MODY) represents the most frequent form of monogenic diabetes mellitus (DM), currently classified in 14 distinct subtypes according to single gene mutations involved in the differentiation and function of pancreatic β-cells. A significant proportion of MODY has unknown etiology, suggesting that the genetic landscape is still to be explored. Recently, novel potentially MODY-causal genes, involved in the differentiation and function of β-cells, have been identified, such as RFX6, NKX2.2, NKX6.1, WFS1, PCBD1, MTOR, TBC1D4, CACNA1E, MNX1, AKT2, NEUROG3, EIF2AK3, GLIS3, HADH, and PTF1A. Genetic and clinical features of MODY variants remain highly heterogeneous, with no direct genotype–phenotype correlation, especially in the low-penetrant subtypes. This is a narrative review of the literature aimed at describing the current state-of-the-art of the novel likely MODY-associated variants. For a deeper understanding of MODY complexity, we also report some related controversies concerning the etiological role of some of the well-known pathological genes and MODY inheritance pattern, as well as the rare association of MODY with autoimmune diabetes. Due to the limited data available, the assessment of MODY-related genes pathogenicity remains challenging, especially in the setting of rare and low-penetrant subtypes. In consideration of the crucial importance of an accurate diagnosis, prognosis and management of MODY, more studies are warranted to further investigate its genetic landscape and the genotype–phenotype correlation, as well as the pathogenetic contribution of the nongenetic modifiers in this cohort of patients. Full article

In recent years, the Chilean agricultural sector has undergone significant changes, but there is a lack of data that can be used to accurately identify these transformations. A study was conducted to assess the effectiveness of different spatial resolutions used by global land cover products (MODIS, ESA and Dynamic World (DW)), in addition to the demi-automated methods applied to them, for the identification of agricultural areas, using the publicly available agricultural survey for 2021. It was found that lower-spatial-resolution collections consistently underestimated crop areas, while collections with higher spatial resolutions overestimated them. The low-spatial-resolution collection, MODIS, underestimated cropland by 46% in 2021, while moderate-resolution collections, such as ESA and DW, overestimated cropland by 39.1% and 93.8%, respectively. Overall, edge-pixel-filtering and a machine learning semi-automated reclassification methodology improved the accuracy of the original global collections, with differences of only 11% when using the DW collection. While there are limitations in certain regions, the use of global land cover collections and filtering methods as training samples can be valuable in areas where high-resolution data are lacking. Future research should focus on validating and adapting these approaches to ensure their effectiveness in sustainable agriculture and ecosystem conservation on a global scale. Full article

Accurately evaluating drought and its effects on the natural environment is difficult in regions with limited climate monitoring stations, particularly in the hyper-arid region of the Sultanate of Oman. Rising global temperatures and increasing incidences of insufficient precipitation have turned drought into a major natural disaster worldwide. In Oman, drought constitutes a major threat to food security. In this study, drought indices (DIs), such as temperature condition index (TCI), vegetation condition index (VCI), and vegetation health index (VHI), which integrate data on drought streamflow, were applied using moderate resolution imaging spectroradiometer (MODIS) data and the Google Earth Engine (GEE) platform to monitor agricultural drought and assess the drought risks using the drought hazard index (DHI) during the period of 2001–2023. This approach allowed us to explore the spatial and temporal complexities of drought patterns in the Najd region. As a result, the detailed analysis of the TCI values exhibited temporal variations over the study period, with notable minimum values observed in specific years (2001, 2005, 2009, 2010, 2014, 2015, 2016, 2017, 2019, 2020, and 2021), and there was a discernible trend of increasing temperatures from 2014 to 2023 compared to earlier years. According to the VCI index, several years, including 2001, 2003, 2006, 2008, 2009, 2013, 2015, 2016, 2017, 2018, 2020, 2021, 2022, and 2023, were characterized by mild drought conditions. Except for 2005 and 2007, all studied years were classified as moderate drought years based on the VHI index. The Pearson correlation coefficient analysis (PCA) was utilized to observe the correlation between DIs, and a high positive correlation between VHI and VCI (0.829, p < 0.01) was found. Based on DHI index spatial analysis, the northern regions of the study area faced the most severe drought hazards, with severity gradually diminishing towards the south and east, and approximately 44% of the total area fell under moderate drought risk, while the remaining 56% was classified as facing very severe drought risk. This study emphasizes the importance of continued monitoring, proactive measures, and effective adaptation strategies to address the heightened risk of drought and its impacts on local ecosystems and communities. Full article

During wintertime temperature inversion episodes, ozone in the Uinta Basin sometimes exceeds the standard of 70 ppb set by the US Environmental Protection Agency. Since ozone formation depends on sunlight, and less sunlight is available during winter, wintertime ozone can only form if snow cover and albedo are high. Researchers have encountered difficulties replicating high albedo values in 3-D weather and photochemical transport model simulations for winter episodes. In this study, a process to assimilate MODIS satellite data into WRF and CAMx models was developed, streamlined, and tested to demonstrate the impacts of data assimilation on the models’ performance. Improvements to the WRF simulation of surface albedo and snow cover were substantial. However, the impact of MODIS data assimilation on WRF performance for other meteorological quantities was minimal, and it had little impact on ozone concentrations in the CAMx photochemical transport model. The contrast between the data assimilation and reference cases was greater for a period with no new snow since albedo appears to decrease too rapidly in default WRF and CAMx configurations. Overall, the improvement from MODIS data assimilation had an observed enhancement in the spatial distribution and temporal evolution of surface characteristics on meteorological quantities and ozone production. Full article

This study discusses the issue of determining the direction and strength of changes taking place in the structure of agricultural land in the mountain and foothill areas of the Carpathians in Poland in comparison with Slovakia, Romania and Ukraine. The most important financial institutional measures dedicated to the protection of the natural environment in Polish agriculture in the Areas facing Natural and other specific Constraints (ANCs) mountain and foothill in the first year of the CAP 2023–2027 were also established. Satellite data from 2001 to 2022 were used. The analyses used the land use classification MCD12Q1 provided by NASA and were made on the basis of satellite imagery collections from the MODIS sensor placed on two satellites: TERRA and AQUA. In EU countries, a decreasing trend in agricultural areas has been observed in areas below 350 m above sea level. In areas above 350 m, this trend weakened or even turned into an upward trend. Only in Ukraine was a different trend observed. It was found that in Poland, the degree of involvement of farmers from mountain and foothill areas in implementing financial institutional measures dedicated to protecting the natural environment during the study period was not satisfactory. Full article

In the absence of forest ecosystem time series data, monitoring proxies such as the enhanced vegetation index (EVI) can inform the capacity of forests to provide ecosystem services. We used MODIS-derived EVI at 250 m and 16-day resolution and Breaks for Additive and Seasonal Trend (BFAST) algorithms to monitor forest EVI changes (breaks and trends) in and around the Algonquin Provincial Park (Ontario, Canada) from 2003 to 2022. We found that relatively little change occurred in forest EVI pixels and that most of the change occurred in non-protected forest areas. Only 5.3% (12,348) of forest pixels experienced one or more EVI breaks and 27.8% showed detectable EVI trends. Most breaks were negative (11,969, 75.3%; positive breaks: 3935, 24.7%) with a median magnitude of change of −755.5 (median positive magnitude: 722.6). A peak of negative breaks (2487, 21%) occurred in the year 2013 while no clear peak was seen among positive breaks. Most breaks (negative and positive) and trends occurred in the eastern region of the study area. Boosted regression trees revealed that the most important predictors of the magnitude of change were forest age, summer droughts, and warm winters. These were among the most important variables that explained the magnitude of negative (R² = 0.639) and positive breaks (R² = 0.352). Forest composition and protection status were only marginally important. Future work should focus on assessing spatial clusters of EVI breaks and trends to understand local drivers of forest vegetation health and their potential relation to forest ecosystem services. Full article

Oases play a crucial role in arid regions within the human–environmental system, holding significant ecological and biological importance. The Oasis Cold Island Effect (OCIE) represents a distinct climatic feature of oases and serves as a vital metric for assessing oasis ecosystems. Previous studies have overlooked the spatial extent of the Oasis Cold Island Effect (OCIE), specifically the boundary delineating areas influenced and unaffected by oases. This boundary is defined as the Oasis Cold Island Footprint (OCI FP). Utilizing Logistic modeling and MODIS data products, OCI FPs were calculated for the Ejina Oasis from 2000 to 2019. The assessment results underscore the accuracy and feasibility of the methodology, indicating its potential applicability to other oases. Spatial and temporal distributions of OCI FPs and the intensity of the Oasis Cold Island Effect Intensity (OCIEI) in the Ejina Oasis were analyzed, yielding the following findings: (1) OCI FP area and complexity were smallest in summer and largest in autumn. (2) Over the period 2000–2019, OCI FPs exhibited a pattern of increase, decrease, and subsequent increase. (3) OCIEI peaks in summer and reaches its lowest point in winter. Lastly, the study addresses current limitations and outlines future research objectives. Full article

Exploring NDVI variation and what drives it on the Qinghai–Tibet Plateau can strategically inform environmental protection efforts in light of global climate change. For this analysis, we obtained MODIS NDVI data collected during the vegetative growing season, vegetation types for the region, and meteorological data for the same period from 2001 to 2020. We performed Theil–Sen trend analysis, Mann–Kendall significance testing, spatial autocorrelation analysis, and Hurst index calculation to review the spatiotemporal changes in NDVI characteristics on the plateau for various vegetation types. We used the correlation coefficients from these analyses to investigate how the NDVI responds to temperature and precipitation. We found the following: (1) Overall, the Qinghai–Tibet Plateau NDVI increased throughout the multi-year growing season, with a much larger area of improvement (65.68%) than of degradation (8.83%). (2) The four main vegetation types were all characterized by improvement, with meadows (72.13%) comprising the largest portion of the improved area and shrubs (18.17%) comprising the largest portion of the degraded area. (3) The spatial distribution of the NDVI had a strong positive correlation and clustering effect and was stable overall. The local clustering patterns were primarily low–low and high–high clustering. (4) The Hurst index had an average value of 0.46, indicating that the sustainability of vegetation is poor; that is, the trend of vegetation change in the growing season in a large part of the Qinghai–Tibet Plateau in the future is opposite to that in the past. (5) The plateau NDVI correlated positively with air temperature and precipitation. However, the correlations varied geographically: air temperature had a wide influence, whereas precipitation mainly influenced meadows and grassland in the northern arid zone. The overall temperature-driven effect was stronger than that of precipitation. This finding is consistent with the current research conclusion that global warming and humidification promote vegetation growth in high-altitude areas and further emphasizes the uniqueness of the Qinghai–Tibet Plateau as a climate-change-sensitive area. This study also offers a technical foundation for understanding how climate change impacts high-altitude ecosystems, as well as for formulating ecological protection strategies for the plateau. Full article

The global, near-real-time monitoring of volcano thermal activity has become feasible through thermal infrared sensors on various satellite platforms, which enable accurate estimations of volcanic emissions. Specifically, these sensors facilitate reliable estimation of Volcanic Radiative Power (VRP), representing the heat radiated during volcanic activity. A critical factor influencing VRP estimates is the identification of hotspots in satellite imagery, typically based on intensity. Different satellite sensors employ unique algorithms due to their distinct characteristics. Integrating data from multiple satellite sources, each with different spatial and spectral resolutions, offers a more comprehensive analysis than using individual data sources alone. We introduce an innovative Remote Sensing Data Fusion (RSDF) algorithm, developed within a Cloud Computing environment that provides scalable, on-demand computing resources and services via the internet, to monitor VRP locally using data from various multispectral satellite sensors: the polar-orbiting Moderate Resolution Imaging Spectroradiometer (MODIS), the Sea and Land Surface Temperature Radiometer (SLSTR), and the Visible Infrared Imaging Radiometer Suite (VIIRS), along with the geostationary Spinning Enhanced Visible and InfraRed Imager (SEVIRI). We describe and demonstrate the operation of this algorithm through the analysis of recent eruptive activities at the Etna and Stromboli volcanoes. The RSDF algorithm, leveraging both spatial and intensity features, demonstrates heightened sensitivity in detecting high-temperature volcanic features, thereby improving VRP monitoring compared to conventional pre-processed products available online. The overall accuracy increased significantly, with the omission rate dropping from 75.5% to 3.7% and the false detection rate decreasing from 11.0% to 4.3%. The proposed multi-sensor approach markedly enhances the ability to monitor and analyze volcanic activity. Full article

Atmospheric water vapor is not only a key element of the global hydrological cycle but also the most abundant greenhouse gas. The phase transition and transportation of water vapor are essential for maintaining global energy balance and regulating hydrological processes. However, due to insufficient meteorological observational data, climate research in Africa faces significant limitations despite its substantial contribution to changes in global precipitable water vapor (PWV). In this study, we used MODIS near-infrared (NIR) PWV products and Berkeley temperature data to depict the spatial–temporal variability in PWV across Africa from 2001 to 2020. The results reveal a significant increasing trend in PWV over Africa, with an increase of 0.0158 cm/year. Nearly 99.96% of Africa shows an increase in PWV, with 88.95% of these areas experiencing statistically significant changes, particularly in central regions of Africa. The increase in PWV is more pronounced in high-value months compared to low-value months. The equatorial region of the Congo Basin exhibits higher PWV, which gradually decreases as latitude increases. Despite significant warming (0.0162 °C/year) in Africa, there is no consistent positive correlation between temperature and water vapor. A positive relationship between PWV and temperature is observed in western Africa, while a negative relationship is noted in eastern and southern Africa on an annual scale. Additionally, an increasing trend in precipitation (4.6669 mm/year) is observed, with a significant positive correlation between PWV and precipitation across most of Africa, although this relationship varies by month. These findings provide valuable insights into the comprehension of the hydrothermal variation in Africa amidst climate warming. Full article

In the Mediterranean region, particularly in Antalya, southern Türkiye, rising forest fire risks due to climate change threaten ecosystems, property, and lives. Reduced soil moisture during the growing season is a key factor increasing fire risk by stressing plants and lowering fuel moisture content. This study assessed soil moisture and fuel moisture content (FMC) in ten fires (2019–2021) affecting over 50 hectares. The Fire Weather Index (FWI) and its components (FFMC, DMC, DC) were calculated using data from the General Directorate of Meteorology, EFFIS (8 km), and ERA5 (≈28 km) satellite sources. Relationships between FMCs, satellite-based soil moisture datasets (SMAP, SMOS), and land surface temperature (LST) data (MODIS, Landsat 8) were analyzed. Strong correlations were found between FWI codes and satellite soil moisture, particularly with SMAP. Positive correlations were observed between LST and FWIs, while negative correlations were evident with soil moisture. Statistical models integrating in situ soil moisture and EFFIS FWI (R: −0.86, −0.84, −0.83 for FFMC, DMC, DC) predicted soil moisture levels during extended fire events effectively, with model accuracy assessed through RMSE (0.60–3.64%). The SMAP surface (0–5 cm) dataset yielded a lower RMSE of 0.60–2.08%, aligning with its higher correlation. This study underlines the critical role of soil moisture in comprehensive fire risk assessments and highlights the necessity of incorporating modeled soil moisture data in fire management strategies, particularly in regions lacking comprehensive in situ monitoring. Full article

The South American Monsoon System, which transports moisture from Amazonia to Central-West Brazil, is an important moisture source for the summer rainy season in this region. While local evapotranspiration also contributes to the atmospheric moisture supply, the balance between local and remote sources during the onset of the rainy season remains uncertain. Our research aimed to quantify the role of local evapotranspiration in initiating the rainy season in Central-West Brazil. By utilizing data from various sources, such as remote sensing (MODIS), modern reanalysis (ECMWF’s ERA5), and composite products of rainfall (CHIRPS), and analyzing them in a comparative way, we conclusively found that local evapotranspiration is the only relevant source of moisture to the atmosphere during the dry-to-wet season transition, preceding the establishment of the monsoon system. Full article

This study addresses the pressing need for flood extent and exposure information in data-scarce and vulnerable regions, with a specific focus on West Africa, particularly Senegal. Leveraging the Google Earth Engine (GEE) platform and integrating data from the Sentinel-1 SAR, Global Surface Water, HydroSHEDS, the Global Human Settlement Layer, and MODIS land cover type, our primary objective is to delineate the extent of flooding and compare this with flooding for a one-in-a-hundred-year flood event, offering a comprehensive assessment of exposure during the period from July to October 2022 across Senegal’s 14 regions. The findings underscore a total inundation area of 2951 square kilometers, impacting 782,681 people, 238 square kilometers of urbanized area, and 21 square kilometers of farmland. Notably, August witnessed the largest flood extent, reaching 780 square kilometers, accounting for 0.40% of the country’s land area. Other regions, including Saint-Louis, Ziguinchor, Fatick, and Matam, experienced varying extents of flooding, with the data for August showing a 1.34% overlap with flooding for a one-in-a-hundred-year flood event derived from hydrological and hydraulic modeling. This low percentage reveals the distinct purpose and nature of the two approaches (remote sensing and modeling), as well as their complementarity. In terms of flood exposure, October emerges as the most critical month, affecting 281,406 people (1.56% of the population). The Dakar, Diourbel, Thiès, and Saint-Louis regions bore substantial impacts, affecting 437,025; 171,537; 115,552; and 77,501 people, respectively. These findings emphasize the imperative for comprehensive disaster preparation and mitigation efforts. This study provides a crucial national-scale perspective to guide Senegal’s authorities in formulating effective flood management, intervention, and adaptation strategies. Full article

In light of recently accelerating global warming, the changes in vegetation trends are vital for the monitoring of the dynamics of both whole ecosystems and individual species. Detecting changes within the time series of specific forest ecosystems or species is very important in the context of assessing their vulnerability to climate change and other negative phenomena. Hence, the aim of this paper was to identify the trend change points and periods of greening and browning in multi-annual time series of the normalised difference vegetation index (NDVI) and enhanced vegetation index (EVI) of four main forest-forming tree species in the temperate zone: pine, spruce, oak and beech. The research was conducted over the last two decades (2002–2022), and was based on vegetation indices data derived from the Moderate Resolution Imaging Spectroradiometer (MODIS). To this end, several research approaches, including calculating the linear trends in the moving periods and BEAST algorithm, were adapted. A pattern of browning then greening then constant was detected for coniferous species, mostly pine. In turn, for broadleaved species, namely oak and beech, a pattern of greening then constant was identified, without the initial phase of browning. The main trend change points seem to be ca. 2006 and ca. 2015 for coniferous species and solely around 2015 for deciduous ones. Full article

Wildfire susceptibility maps play a crucial role in preemptively identifying regions at risk of future fires and informing decisions related to wildfire management, thereby aiding in mitigating the risks and potential damage posed by wildfires. This study employs eXplainable Artificial Intelligence (XAI) techniques, particularly SHapley Additive exPlanations (SHAP), to map wildfire susceptibility in Izmir Province, Türkiye. Incorporating fifteen conditioning factors spanning topography, climate, anthropogenic influences, and vegetation characteristics, machine learning (ML) models (Random Forest, XGBoost, LightGBM) were used to predict wildfire-prone areas using freely available active fire pixel data (MODIS Active Fire Collection 6 MCD14ML product). The evaluation of the trained ML models showed that the Random Forest (RF) model outperformed XGBoost and LightGBM, achieving the highest test accuracy (95.6%). All of the classifiers demonstrated a strong predictive performance, but RF excelled in sensitivity, specificity, precision, and F-1 score, making it the preferred model for generating a wildfire susceptibility map and conducting a SHAP analysis. Unlike prevailing approaches focusing solely on global feature importance, this study fills a critical gap by employing a SHAP summary and dependence plots to comprehensively assess each factor’s contribution, enhancing the explainability and reliability of the results. The analysis reveals clear associations between factors such as wind speed, temperature, NDVI, slope, and distance to villages with increased fire susceptibility, while rainfall and distance to streams exhibit nuanced effects. The spatial distribution of the wildfire susceptibility classes highlights critical areas, particularly in flat and coastal regions near settlements and agricultural lands, emphasizing the need for enhanced awareness and preventive measures. These insights inform targeted fire management strategies, highlighting the importance of tailored interventions like firebreaks and vegetation management. However, challenges remain, including ensuring the selected factors’ adequacy across diverse regions, addressing potential biases from resampling spatially varied data, and refining the model for broader applicability. Full article