Search Results (695)

Southeast Asia is an essential region for companies carrying out large-scale land acquisitions (LSLAs). Exploring the distribution patterns and influencing factors of LSLA projects in this region is of great practical significance for summarizing the characteristics of LSLA projects in Southeast Asia, for gaining a thorough understanding of LSLA project development rules, and for formulating reasonable policies to guide local LSLA projects. This study explores the spatial distribution and influencing factors of LSLA projects in Southeast Asia using the mean center method, the kernel density estimation method, and the grey correlation method. The findings indicate the following: Firstly, the majority of LSLA projects in Southeast Asia are located in the Indo-China Peninsula, Cambodia, Myanmar, Laos, and other countries, which represent significant regions of interest for LSLA projects in this region. Secondly, the spatial distribution of LSLA intention projects and LSLA contract projects in Southeast Asia is similar, whereas LSLA production projects differ from the former two. Thirdly, the scale of LSLA projects in Southeast Asia is closely related to the host country’s natural resources, socio-economic conditions, governance, and market environment. The total GDP, per capita arable land area, net foreign direct investment inflow, and political stability have been identified as exerting a significant influence on investment corporations’ selection of LSLA host countries. Full article

Background: WHO and WOAH advocate for annual high-coverage canine rabies vaccination campaigns as the most sustainable approach to eliminate the risk of dog rabies transmission to humans. It is estimated that Cambodia has one of the highest human rabies deaths per capita of any country (5.8 human deaths per 100,000 people), highlighting the urgent need to implement an effective canine rabies vaccination program. To this end, a coalition of government and non-government organizations conducted a pioneering short-duration dog rabies vaccination campaign over 10 days across Phnom Penh and Kandal Provinces in May 2023. Methods: Over 10 working days, 120 vaccination teams, each consisting of two vaccinators and one tuk-tuk driver, traveled door-to-door to deliver parenteral rabies vaccines to all dogs that could be held by the teams or members of the community. Spatial team management and data collection were conducted through the WVS Data Collection Application. Results: A total of 74,983 dogs were vaccinated, giving a mean vaccination rate of 62.5 dogs per team per day. An additional 2145 cats were vaccinated. Of all dogs encountered by the teams, 84.0% could be vaccinated, with 99.1% of those being identified as owned. Post-vaccination surveys of 4356 households estimated a mean vaccination coverage of 70.7% in owned dogs across the districts of Phnom Penh Province. Conclusion: Short-duration, large-scale canine rabies vaccination campaigns can achieve high vaccination coverage using a door-to-door approach in urban centers of Cambodia. Data gathered through the campaign yielded insights to support the refinement and planning of a wider rabies control strategy and is anticipated to drive further support for subsequent campaigns in Cambodia. Full article

Dental practitioners, as part of their work, are exposed to a variety of hazards. This highlights the ongoing need for attention to occupational health in the dental field. A cross-sectional study was organised to investigate the range, prevalence, and associated factors for occupational health problems related to dental practice among Cambodian dentists. Participants underwent a face-to-face interview to explore dentists work-related health problems; 106 Cambodian dentists participated in this study, of which 68.9% were male. Ages ranged from 29 to 71 years, averaging 36.1 years, with the majority (77.4%) in the 29–40 age group. They had 5 to 18 years of practice experience, and worked an average of 52.2 h per week. Commonly reported health issues included back pain (88.7%), headaches (81.1%), shoulder pain (78.3%), arm/hand pain (57.5%), and eye problems (48.1%). Additionally, 38.7% of participants felt stressed and 19.8% depressed. Some reported suicidal thoughts and taking medication for depression. Despite these challenges, 91.5% enjoyed practicing dentistry. These findings highlight the need for interventions and strategies to address the physical and mental well-being of Cambodian dentists. By addressing these issues, steps can be taken to enhance the working conditions and professional satisfaction of dental professionals, ultimately benefiting both the practitioners and their patients. Full article

The Greater Mekong Subregion (GMS) economic cooperation program is an effective and fruitful regional cooperation initiative for socioeconomic development in Asia; however, the vegetation change trends and directions in the GMS caused by rapid development remain unknown. In particular, there is a current lack of comparative studies on vegetation changes in various countries in the GMS. Based on the MODIS normalized difference vegetation index (NDVI) time series data, this study analyzed the spatiotemporal patterns of vegetation coverage and their trends in the GMS from 2000 to 2022 using the Theil–Sen slope estimation, the Mann–Kendall mutation test, and the gravity center migration model. The key findings were as follows: (1) the NDVI in the GMS showed an overall upward fluctuating trend over the past 23 years, with an annual growth rate of 0.11%. The NDVI changes varied slightly between seasons, with the greatest increases recorded in summer and winter. (2) The spatial distribution of NDVI in the GMS varied greatly, with higher NDVI values in the north–central region and lower NDVI values in the south. (3) A total of 66.03% of the GMS area showed increments in vegetation during the studied period, mainly in south–central Myanmar, northeastern Thailand, Vietnam, and China. (4) From 2000 to 2022, the gravity center of vegetation greenness shifted northward in the GMS, especially from 2000 to 2005, indicating that the growth rates of vegetation in the north–central part of the GMS were higher than those in the south. Furthermore, the vegetation coverage in all countries, except Cambodia, increased, with the most pronounced growth recorded in China. Overall, these findings can provide scientific evidence for the GMS to enhance ecological protection and sustainable development. Full article

Limited data are available regarding the effect of metabolic syndrome on heart failure (HF) development in young individuals. Utilizing data from the Korean National Health Insurance Service, we included a total of 1,958,284 subjects in their 40s who underwent health screening between January 2009 and December 2009 in Korea. Subjects were classified into three groups: normal, pre-metabolic syndrome (Pre-MetS), and metabolic syndrome (MetS). MetS was identified in 10.58% of males and 5.21% of females. The hazard ratio for HF in subjects with MetS was 1.968 (95% CI: 1.526–2.539) for males and 2.398 (95% CI: 1.466–3.923) for females. For those with Pre-MetS, the hazard ratio was 1.607 (95% CI: 1.293–1.997) in males and 1.893 (95% CI: 1.43–2.505) in females. Additionally, acute myocardial infarction and low hemoglobin levels were identified as significant risk factors for HF in both genders. MetS approximately doubled the risk of developing HF in individuals in their 40s. Pre-MetS was also a significant risk factor for HF in this population. Full article

French Guiana lacks a dedicated model for developing an early warning system tailored to its entomological contexts. We employed a spatiotemporal modeling approach to predict the risk of Aedes aegypti larvae presence in local households in French Guiana. The model integrated field data on larvae, environmental data obtained from very high-spatial-resolution Pleiades imagery, and meteorological data collected from September 2011 to February 2013 in an urban area of French Guiana. The identified environmental and meteorological factors were used to generate dynamic maps with high spatial and temporal resolution. The study collected larval data from 261 different surveyed houses, with each house being surveyed between one and three times. Of the observations, 41% were positive for the presence of Aedes aegypti larvae. We modeled the Aedes larvae risk within a radius of 50 to 200 m around houses using six explanatory variables and extrapolated the findings to other urban municipalities during the 2020 dengue epidemic in French Guiana. This study highlights the potential of spatiotemporal modeling approaches to predict and monitor the evolution of vector-borne disease transmission risk, representing a major opportunity to monitor the evolution of vector risk and provide valuable information for public health authorities. Full article

Extreme rainfall, also known as heavy rainfall or intense precipitation, is a weather event characterized by a significant amount of rainfall within a short period. This study analyzes the trends in extreme precipitation indices at 17 stations in four main regions in Cambodia—the Tonle Sap, coastal, Mekong Delta, and Upper Mekong regions—between 1991 and 2021. Analyzing the data with RClimDex v1.9 reveals diverse spatial and temporal variations. The statistical analysis of the extreme rainfall indices in Cambodia from 1991 to 2021 reveals significant trends. In the Tonle Sap region, consecutive dry days (CDDs) increased at most stations, except Battabang, Kampong Thmar, and Pursat, while consecutive wet days (CWDs) increased at most stations. These trends align with rising temperatures and reduced forest cover. In the coastal region, particularly at the Krong Khemarak Phummin station, most rainfall indices increased, with a slope value of 89.94 mm/year. The extreme rainfall indices max. 1-day precipitation (RX1day) and max. 5-day precipitation (RX5day) also increased, suggesting higher precipitation on days exceeding the 95th (R95p) and 99th percentiles (R99p). The Kampot station showed a significant increase in CDDs, indicating a heightened drought risk. In the Mekong Delta, the Prey Veng station recorded a decrease in the CDDs slope value by −4.892 days/year, indicating potential drought risks. The Stung Treng station, which is the only station in Upper Mekong, showed a decreasing trend in CDDs with a slope value of −1.183 days/year, indicating a risk of extreme events. These findings underscore the complex interplay between climate change, land use, and rainfall patterns in Cambodia. Full article

To measure the long-range transport of PCDD/Fs, a background sampling site at Mt. Lulin station (Taiwan) was selected based on meteorological information and its location relative to burning events in Southeast Asia. During regular sampling periods, a higher concentration of PCDD/Fs was recorded in 2008 at Mt. Lulin station during La Niña events, with levels reaching 390 fg I-TEQ/m³. In contrast, a higher concentration of 483 fg I-TEQ/m³ was observed in 2013 during biomass burning events. This indicates that La Niña affects the ambient PCDD/F concentrations. The ratio of ΣPCDD/ΣPCDF was 0.59, suggesting significant long-range transport contributions from 2007 to 2023. From 2007 to 2015, the predominant species was 2,3,4,7,8-PCDF, accounting for 25.3 to 39.6% of the total PCDD/Fs. From 2018 onward, 1,2,3,7,8-PCDD became more dominant, accounting for 15.0 to 27.1%. According to the results from the receptor model PMF (n = 150), the sources of PCDD/Fs were identified as dust storms and monsoon events (19.3%), anthropogenic activity (28.5%), and biomass burning events (52.2%). The PSCF values higher than 0.7 highlighted potential PCDD/F emission source regions for Mt. Lulin during biomass burning events, indicating high PSCF values in southern Thailand, Cambodia, and southern Vietnam. Full article

This study examines the current state of China’s agricultural exports to ASEAN countries using a segmented export structure analysis via a stochastic frontier gravity model, based on panel data from 2007 to 2020. The results indicate that: (1) China’s primary agricultural exports to ASEAN countries include plant products, food and beverages, and tobacco, with animal products mainly exported to Thailand, plant products mainly exported to Vietnam, and animal and plant fats, food, beverages, and tobacco mainly exported to Malaysia. (2) The economic scale and population size of China and ASEAN countries have differing impacts on various markets, while distance significantly negatively affects the exports of animal products, plant products, food, beverages, and tobacco. Additionally, ASEAN countries’ per capita carbon emissions positively influence the exports of these product categories. (3) The liner shipping connectivity index is significantly negatively correlated with trade inefficiency. The influences of financial freedom, trade freedom, investment freedom, and government expenditure on trade inefficiency vary across ASEAN countries. (4) China’s export efficiency for animal products, plant products, food, beverages, and tobacco has increased rapidly to Thailand and Vietnam, with Malaysia and Singapore showing high export efficiency, while that to Cambodia lags. (5) China exhibits significant export potential to Thailand, Indonesia, and Vietnam, with substantial expansion opportunities in Indonesia. Moreover, China’s export potential and opportunities in Cambodia are steadily increasing. Full article

Student leadership prepares students for responsibilities, such as taking on specific tasks and assuming leadership roles in their future personal and professional lives. Developing students’ leadership profiles is among the important goals of educational systems aiming for future generations to take responsibility and advance their countries. With this perspective in mind, the PISA assessment includes items to measure students’ leadership behaviors. This study aims to extract student leadership profiles from the leadership-related items in the PISA 2022 application, using data from Cambodia, Peru, Paraguay, and Guatemala, which have different governance systems and cultural characteristics. The second purpose of the research is to determine the distribution of the identified leadership profiles in these countries and explain them in the context of governance and cultural characteristics. Latent class analysis was used to determine student leadership profiles. Accordingly, two-class and three-class latent models were found to be the most suitable models to explain student profiles. While the distinction between student profiles is more pronounced in the two-class model, the three-class model provides more detailed information about student profiles. In this respect, two-class and three-class latent models are reported comparatively. In the two-class latent model, students are labeled as the “Shy or Lack of Self-Confidence Group” and the “Active Leader or Influential Group”. In the three-class latent model, students are labeled as the “Moderate or Passive Leader Group”, the “Strong Leader or Influential Group”, and the “Avoidant or Leadership-Uncomfortable Group”. In both models, it is one of the striking findings that Cambodian students are in the low leadership profile, and Peruvian students are in the high leadership profile. Full article

Ramon syndrome (MIM 266270) is an extremely rare genetic syndrome, characterized by gingival fibromatosis, cherubism-like lesions, epilepsy, intellectual disability, hypertrichosis, short stature, juvenile rheumatoid arthritis, and ocular abnormalities. Hereditary or non-syndromic gingival fibromatosis (HGF) is also rare and considered to represent a heterogeneous group of disorders characterized by benign, slowly progressive, non-inflammatory gingival overgrowth. To date, two genes, ELMO2 and TBC1D2B, have been linked to Ramon syndrome. The objective of this study was to further investigate the genetic variants associated with Ramon syndrome as well as HGF. Clinical, radiographic, histological, and immunohistochemical examinations were performed on affected individuals. Exome sequencing identified rare variants in TBC1D2B in both conditions: a novel homozygous variant (c.1879_1880del, p.Glu627LysfsTer61) in a Thai patient with Ramon syndrome and a rare heterozygous variant (c.2471A>G, p.Tyr824Cys) in a Cambodian family with HGF. A novel variant (c.892C>T, p.Arg298Cys) in KREMEN2 was also identified in the individuals with HGF. With support from mutant protein modeling, our data suggest that TBC1D2B variants contribute to both Ramon syndrome and HGF, although variants in additional genes might also contribute to the pathogenesis of HGF. Full article

Land use/cover change(LUCC) has a significant impact on the ecological environment. Within the Belt and Road Initiative (BRI), as the largest cross-spatial cooperation initiative in human history, one of the core issues is how to scientifically and effectively use and manage the land in the region to prevent the destruction of important ecological and environmental resources. In order to reduce impact on the latter, in this study, we used the bivariate choropleth–multiple-criteria decision analysis (BC-MCDA) method based on the connotation of the sustainable development goals to construct an ecological and environmental risk warning framework. We found that in the study area, 10.51% of the land has high ecological and environmental risk and importance, corresponding to conflict zones, which require special attention. Conflict areas are mainly distributed in the Gangetic Plain in India, the plains in central and southern Cambodia, the Indonesian archipelago, and the southern coastal areas of China. Due to the uneven spatial distributions of population and important ecological and environmental resources, the pressure on this type of land use is very high. A share of 8.06% of the land has high risk–low importance, corresponding to economic development zones. Following years of human development, the ecological and environmental value of this type of land is low. A share of 58.75% of the land has low risk and importance, corresponding to wilderness areas. The natural climatic conditions of this type of land are relatively poor, often characterized by a cold climate or water scarcity, and the human interference index is low. A share of 22.68% of the land has low risk–high importance, corresponding to ecological conservation areas, which are the most important areas for ecological function services for humans at present. Finally, we proposed development suggestions for each type of land. Full article

Municipal solid waste management in developing countries faces limitations, especially concerning technologies for treatment and disposal, which is crucial for achieving environmental and economic sustainability goals. This paper investigates municipal solid waste management in Laos, compared with the ASEAN-Japan regions, focusing on background information, waste characteristics, environmental impact, and treatment technologies for resource utilization. The findings indicate a continuous rise in municipal waste generation in Laos, particularly in the capital Vientiane, from 0.21 million tons in 2012 to 0.37 million tons in 2021. Treatment methods include unsanitary landfilling, basic recycling, and open dumping, as well as burning or discharge into rivers, posing potential risks to the environment and human health. Japan and Singapore have shown decreasing trends, with Japan reducing from 45.23 million tons in 2012 to 40.95 million tons in 2021 and Singapore from 7.27 million tons in 2021 to 6.94 million tons in 2021. Laos encounters challenges in managing municipal waste, especially in waste recovery and waste-to-energy practices, crucial elements of integrated solid waste management aimed at promoting environmental and economic sustainability. Enhancing waste management in Laos involves developing a waste management act with segregation, recycling, and extended producer responsibility policies. Implementing mechanical biological treatment facilities, waste-to-energy plants, and upgraded landfills is crucial. Capacity building and public awareness campaigns on waste management will improve sustainability, reduce environmental impacts, and advance sustainable development goals for sustainable cities and communities. Full article

The Lower Mekong Basin has had extensive hydropower dam development, which changes its hydrologic conditions and threatens the exceptional aquatic biodiversity. This study quantifies the degree of hydrologic change between pre-impact (1965–1968) and post-impact (2018–2021) peak hydropower development in two major tributaries of the Lower Mekong Basin—the Sekong River, with the fewest dams, and the Sesan River, with the most dams. Both rivers have historically supported migratory fishes. We used daily pre- and post-impact data and the Indicators of Hydrologic Alteration framework to evaluate streamflow changes from dam development. We found significant changes in low- and high-magnitude flows in the pre- and post-impact periods of dam development. For the Sekong River, minimum flow had large fluctuations, with increases of 290% to 412% compared to the pre-impact period, while the Sesan River’s minimum flow ranged from 120% to 160% more than pre-impact. Dry season flows increased by 200 ± 63% on average in the Sekong River, which was caused by releases from upstream dams. Meanwhile, the Sesan River’s dry season flows increased by 100 ± 55% on average. This study indicates that seasonal flow changes and extreme flow events occurred more frequently in the two basins following dam construction, which may threaten the ecosystem’s function. Full article

Poor mastitis control favors intramammary infection (IMI), which always involves CNS. This study aimed to determine the relationships of IL-4, IL-6, and IL-10 in mastitis milk with concurrent infection, bacterial pathogens, SCC, and MDA, an oxidative stress marker. All mastitis quarters from five smallholder dairy farms were sampled aseptically before morning milking and again before afternoon milking for bacteriological identification using MALDI-TOF mass spectrometry. The samples with the concomitant infection between streptococci and CNS and their pairs of another sample from the quarters were selected. In addition, samples were randomly chosen to have a controlled single infection. IL-4, IL-6, and IL-10 were measured with ELISA kits. MDA was measured using HPLC, while SCC was measured using Fossomatic™ FC. The results from a repeated measure analysis showed that IL-4 positively correlated with SCC, while IL-6 showed a negative trend. IL-4 levels were highest in CNS infections and significantly higher than in non-infected or mixed infections (p < 0.05). The IL-6 level of the mixed bacteria was highest and showed a different trend from non-infection, and the quarter was infected with streptococcal bacteria. In conclusion, from a single infection, the streptococci and CNS quarter showed varied immune responses, including trendily higher IL-6 and IL-4. Full article