Search Results (255)

There are numerous methods for detecting interturn faults (ITFs) in the field winding of synchronous machines (SMs). One effective approach is based on comparing theoretical and measured excitation currents. This method is unaffected by rotor temperature in static excitation SMs. However, this paper investigates the influence of rotor temperature in brushless synchronous machines (BSMs), where rotor temperature significantly impacts the exciter excitation current. Extensive experimental tests were conducted on a special BSM with measurable rotor temperature. Given the challenges of measuring rotor temperature in industrial machines, this paper explores the feasibility of using stator temperature in the exciter field current estimation model. The theoretical exciter field current is calculated using a deep neural network (DNN), which incorporates electrical brushless synchronous generator output values and stator temperature, and it is subsequently compared with the measured exciter field current. This method achieves an error rate below 0.5% under healthy conditions, demonstrating its potential for simple implementation in industrial BSMs for ITF detection. Full article

DUNE is a next-generation long-baseline neutrino oscillation experiment. It is expected to measure, with unprecedented precision, the atmospheric oscillation parameters, including the CP-violating phase ${\delta }_{CP}$. Moreover, several studies have suggested that its unique features should allow DUNE to probe several new physics scenarios. In this work, we explore the performances of the DUNE far detector in constraining new physics if a high-energy neutrino flux is employed (HE-DUNE). We take into account three different scenarios: Lorentz Invariance Violation (LIV), Long-Range Forces (LRFs) and Large Extra Dimensions (LEDs). Our results show that HE-DUNE should be able to set bounds competitive to the current ones and, in particular, it can outperform the standard DUNE capabilities in constraining CPT-even LIV parameters and the compactification radius $R_{ED}$ of the LED model. Full article

Mineral bone disease (MBD) is common in dialysis patients. Genetics and the hormonal environment influence the clinical picture and outcomes of women. This study aimed to determine how these factors affect mortality. In 234 female dialysis patients on Continuous Ambulatory (48%) or Automated (29%) Peritoneal Dialysis or Hemodialysis (23%), MBD biochemical variables, as well as bone density and genetic Bsm1 polymorphism of vitamin D receptor (VDR) were performed at baseline. The cohort was followed-up by 17 (IQ range 15–31) months. According to VDR polymorphism, the distribution of patients was bb: 64% and BB+Bb: 36%. Fifty-five patients died from all-cause mortality; the hs-C-reactive protein level was the most significant risk in multivariate Cox analysis. Nineteen died from cardiovascular mortality. None of the variables were significant for cardiovascular mortality. Patients with bb plus inflammation had the highest risk in the analysis; the significance persisted after adjustment for age, diabetes, and parathyroid hormone levels HR 2.33 (95% CI, 1.01–8.33) and after further adjustment for time on dialysis, albumin, and Osteoprotegerin levels HR 3.49 (95% CI, 1.20–10.9). The presence of the bb genotype from VDR and inflammation had the highest risk of death from all-cause mortality in females on CAPD, APD, and HD patient. Full article

An experiment was conducted to determine the apparent metabolizable energy (AME) and nitrogen-corrected AME (AMEn) of defatted black soldier fly larvae meal (BSM), full-fat dry larvae meal (BSL), and larvae fat (LF) for broiler chickens. The BSM, BSL, and LF contained on a g/kg basis, respectively, crude protein, 459, 399, 0; crude fat, 171, 240, 923; dry matter, 963, 940, 997; neutral detergent fiber, 210, 333, 0; acid detergent fibers, 95, 93, 0; and gross energy (MJ/kg), 22.04, 22.78, 38.16. An AME bioassay was performed wherein broilers were fed four experimental diets (a maize–wheat–soy basal diet and three test diets containing 100 g/kg BSM, BSL, or LF, respectively). The AME of BSM, BSL, and LF was calculated based on the differences between the AME values of basal and test diets (substitution method). The AME and AMEn for BSM, BSL, and LF were determined to be 18.20 and 17.40; 17.60 and 16.50; and 36.50 and 35.60 MJ/kg DM, respectively. There were no significant differences (p > 0.05) between nutrient retention coefficients of dry matter, N, and fat. The results showed that the examined products from black soldier fly larvae are a good source of available energy and crude protein (BSL and BSM) and can be incorporated in broiler diets as alternative protein and energy sources. Full article

Twelve commercial species exploited in the eastern Guangdong and southern Fujian waters were assessed using the Catch-Maximum Sustainable Yield (CMSY) and Bayesian Schaefer Model (BSM) methods. The carrying capacity (k), intrinsic rate of population growth (r), maximum sustainable yield (MSY), and relative biomass (B_end/k and B/B_MSY) were estimated. The current stock status was defined by B/B_MSY and fishing mortality (F/F_MSY). The results indicate that seven stocks were overfished or below safe biological limits (B/B_MSY < 0.5 or F/F_MSY > 1), two stocks were in a recovery phase (0.5 < B/B_MSY < 1, F/F_MSY < 1), and three stocks were under sustainable fishing pressure with healthy biomass, capable of producing yields close to the MSY (B/B_MSY > 1, F/F_MSY < 1). The stock statuses are consistent with previous studies on the utilization of pelagic fisheries in the eastern Guangdong and southern Fujian waters and with those assessments in other waters. The results of the assessments suggest that these stocks could be expected to produce higher sustainable catches if permitted to rebuild; thus, more effective and proactive management is needed in this upwelling fishing ground. Full article

Soil erosion and hydrogeological risk are critical phenomena gaining increased recognition within the scientific community. Although these occurrences are naturally occurring, human activities can exacerbate their impacts. For example, deforestation consistently amplifies soil erosion. This study examines two distinct forest management strategies aimed at addressing soil erosion: the Banded Standards Method (BSM) and the Scattered Standards Method (SSM). We conducted a field experiment in two test areas located in central Italy, with one area employing the BSM and the other implementing the SSM. Two soil erosion plots were established, representing prototypes of a novel erosion monitoring apparatus called the Natural Erosion Trap (NET), or Diabrosimeter, specifically designed for forest environments. At regular intervals, particularly after significant storm events, sediment and leaf litter accumulated within the erosion plots were collected, dried, and weighed to quantify erosion rates and assess the efficacy of the silvicultural methods under investigation. The results revealed a 30.72% reduction in the eroded material with BSM compared to SSM, underscoring BSM’s ability to mitigate potential hazards and preserve environmental integrity. Full article

Vitamin D deficiency and type 2 diabetes mellitus are risk factors for colorectal cancer, suggesting a role for vitamin D receptor (VDR) and insulin receptor (INSR) gene polymorphisms. We investigated the prevalence of the VDR-BsmI (rs1544410) and NsiI A/G-INSR (rs2059806) polymorphisms and their associations with colorectal adenoma (CRA) in a Romanian population. A case–control study was conducted with 110 participants (67 with CRA and 43 controls) who underwent colonoscopy. Polymerase chain reaction–restriction fragment length polymorphism analysis was used to determine the genotype and allele frequencies of the two polymorphisms. Regarding rs1544410 and CRA patients, genotype distribution was 35% B/B, 47% B/b, and 19% b/b. In the controls, the distribution was 21% B/B, 45% B/b, and 34% b/b. For rs2059806, 12% of CRA patients had A/A, 30% A/G, and 58% G/G, while 8% of the controls had A/A, 40% A/G, and 52% G/G. The recessive model showed an odds ratio of 2.84 (95% CI: 1.04–7.72, p = 0.033) for the b/b genotype. CRA patients with b/b or G/G genotypes were diagnosed at a younger age. The b allele of the rs1544410 was a risk factor for CRA. Patients with the b/b and G/G genotypes were diagnosed earlier. Full article

Research on computer-aided arrhythmia classification is actively conducted, but the limited generalization capacity constrains its applicability in practical clinical settings. One of the primary challenges in deploying such techniques in real-world scenarios is the inter-patient variability and the consequent performance degradation. In this study, we leverage our previous innovation, the n-beat-score map (n-BSM), to introduce an adversarial framework to mitigate the issue of poor performance in arrhythmia classification within the inter-patient paradigm. The n-BSM is a 2D representation of the ECG signal, capturing its constituent beat characteristics through beat-score vectors derived from a pre-trained beat classifier. We employ adversarial learning to eliminate patient-dependent features during the training of the beat classifier, thereby generating the patient-independent n-BSM (PI-BSM). This approach enables us to concentrate primarily on the learning characteristics associated with beat type rather than patient-specific features. Through a beat classifier pre-trained with adversarial learning, a series of beat-score vectors are generated for the beat segments that make up a given ECG signal. These vectors are then concatenated chronologically to form a PI-BSM. Utilizing PI-BSMs as the input, an arrhythmia classifier is trained to differentiate between distinct types of rhythms. This approach yields a 14.27% enhancement in the F1-score in the MIT-BIH arrhythmia database and a 4.97% improvement in cross-database evaluation using the Chapman–Shaoxing 12-lead ECG database. Full article

Lichens have developed numerous adaptations to optimize their survival in various environmental conditions, largely by producing secondary compounds by the fungal partner. They often have antibiotic properties and are involved in protection against intensive UV radiation, pathogens, and herbivores. To contribute to the knowledge of the arsenal of secondary compounds in a crustose lichen species, we sequenced and assembled the genome of Toniniopsis dissimilis, an indicator of old-growth forests, using Oxford Nanopore Technologies (ONT, Oxford, UK) long reads. Our analyses focused on biosynthetic gene clusters (BGCs) and specifically on Type I Polyketide (T1PKS) genes involved in the biosynthesis of polyketides. We used the comparative genomic approach to compare the genome of T. dissimilis with six other members of the family Ramalinaceae and twenty additional lichen genomes from the database. With only six T1PKS genes, a comparatively low number of biosynthetic genes are present in the T. dissimilis genome; from those, two-thirds are putatively involved in melanin biosynthesis. The comparative analyses showed at least three potential pathways of melanin biosynthesis in T. dissimilis, namely via the formation of 1,3,6,8-tetrahydroxynaphthalene, naphthopyrone, or YWA1 putative precursors, which highlights its importance in T. dissimilis. In addition, we report the occurrence of genes encoding ribosomally synthesized and posttranslationally modified peptides (RiPPs) in lichens, with their highest number in T. dissimilis compared to other Ramalinaceae genomes. So far, no function has been assigned to RiPP-like proteins in lichens, which leaves potential for future research on this topic. Full article

Despite the recognized influence of body mass on combat techniques, the relationship between body segment mass (BSM) and combat moves remains unexplored. This study aimed to examine the relationship between the striking arm mass (SAM), kicking leg mass (KLM), and body mass (BM) and the dynamic forces of direct punch (DP), palm strike (PS), elbow strike (ES), front kick (FK), and countermovement jump (CMJ) performance. Sixteen male military cadets (22.3 ± 1.8 years, 181.4 ± 7.0 cm, 82.1 ± 8.5 kg) performed combat techniques, with their performance measured by using a force plate and their body segment mass assessed by dual-energy X-ray absorptiometry. Spearman’s correlation analysis, the Wilcoxon test, and Cohen’s d were applied. The results indicated the relationship between the KLM or BM and the FK impulse (r = 0.64, p = 0.01; r = 0.52, p = 0.04, respectively) and CMJ impact force (r = 0.80, p ≤ 0.01; r = 0.70, p ≤ 0.01, respectively). The FK peak and impact forces were moderately correlated with the CMJ jump height (r = 0.74, p ≤ 0.01; r = 0.77, p ≤ 0.01). Moreover, the FK peak force was significantly higher than that for DP, PS, and ES (p ≤ 0.01, d = 3.32; p ≤ 0.01, d = 1.6; and p = 0.013, d = 1.3, respectively). The highest relationship was found between the KLM and the FK impulse; however, the difference in variability explained by the KLM versus the body mass was only 12%. This suggests that knowledge of the BSM did not provide a significantly better estimate of the dynamic forces of the punches and FKs than the knowledge of the BM. Full article

A total hip arthroplasty (THA) can improve quality of life, but loosening of the hip prosthesis is a complex problem in which vitamin D may also play a role. The Vitamin D Receptor (VDR) is involved in the response of cells to the action of vitamin D, and its genetic variability raises the question of whether individual differences could influence the risk of prosthesis loosening. The aim of this study was to investigate the relationship between VDR single nucleotide polymorphisms (SNPs) (ApaI, BsmI, FokI and TaqI) and the serum VDR and 25(OH)D levels in three groups of patients: (1) arthroscopy patients after THA without loosening of the prosthesis (CA—Control Arthroplasty), (2) patients after THA with loosened hip prostheses (L—Loosening) and (3) the control group (C—Control). Our results suggest that the genotypes tt of TaqI, BB of BsmI, and FF of FokI may influence the VDR effect in patients with loosened protheses. Our results showed that the ACAC haplotype (AtBF) was over two times more frequent in the L group than in CA + C: OR =2.35 [95% CI 1.44–3.83; p = 0.001]. There was no significant correlation between the VDR and serum 25(OH)D levels, but there were differences between studied groups. Full article

Since the early 21st century, within fuzzy mathematics, there has been a stream of research in the field of option pricing that introduces vagueness in the parameters governing the movement of the underlying asset price through fuzzy numbers (FNs). This approach is commonly known as fuzzy random option pricing (FROP). In discrete time, most contributions use the binomial groundwork with up-and-down moves proposed by Cox, Ross, and Rubinstein (CRR), which introduces epistemic uncertainty associated with volatility through FNs. Thus, the present work falls within this stream of literature and contributes to the literature in three ways. First, analytical developments allow for the introduction of uncertainty with intuitionistic fuzzy numbers (IFNs), which are a generalization of FNs. Therefore, we can introduce bipolar uncertainty in parameter modelling. Second, a methodology is proposed that allows for adjusting the volatility with which the option is valued through an IFN. This approach is based on the existing developments in the literature on adjusting statistical parameters with possibility distributions via historical data. Third, we introduce into the debate on fuzzy random binomial option pricing the analytical framework that should be used in modelling upwards and downwards moves. In this sense, binomial modelling is usually employed to value path-dependent options that cannot be directly evaluated with the Black–Scholes–Merton (BSM) model. Thus, one way to assess the suitability of binomial moves for valuing a particular option is to approximate the results of the BSM in a European option with the same characteristics as the option of interest. In this study, we compared the moves proposed by Renddleman and Bartter (RB) with CRR. We have observed that, depending on the moneyness degree of the option and, without a doubt, on options traded at the money, RB modelling offers greater convergence to BSM prices than does CRR modelling. Full article

This paper attempts to classify various blinding strategies used in particle physics. It argues that the blinding technique is not used consistently throughout searches for new physics. More importantly, the blinding technique, in its traditional sense, cannot be applicable for many current and future searches when the statistical precision of data significantly exceeds the current level of our understanding of Standard Model (SM) backgrounds. Full article

Background: The etiopathogenesis of inflammatory bowel disease (IBD) is still unclear. Prior studies suggest genetic components that may influence the incidence and severity of the disease. Additionally, it was shown that low levels of serum vitamin D may have an impact on the clinical course of the disease due to its effect on the immunological system. Methods: We aimed to investigate the correlation between the incidence of vitamin D receptor (VDR) gene polymorphisms (rs11568820, rs10735810, rs1544410, rs7975232, and rs731236, commonly described as Cdx2, FokI, Bsm, ApaI, and TaqI, respectively) and vitamin D concentration with the clinical course of IBD (disease activity, extent of the intestinal lesions). Data were obtained from 62 patients with IBD (34 with Crohn’s disease, 28 with ulcerative colitis), aged 3–18 years, and compared with controls (N = 47), aged 8–18 years. Results: Although there was no difference in the incidence of individual genotypes between the study groups (IBD, C) in all the polymorphisms examined, we described a significant increase in the chance of developing IBD for heterozygotes of Cdx2 (OR: 2.3, 95% CI 0.88–6.18, p = 0.04) and BsmI (OR: 2.07, 95% CI 0.89–4.82, p = 0.048) polymorphisms. The mean serum 25OHD level in patients with IBD was significantly higher compared with the controls (19.87 ng/mL vs. 16.07 ng/mL; p = 0.03); however, it was still below optimal (>30 ng/mL). Furthermore, a significant correlation was found between vitamin D level and TaqI in patients with IBD (p = 0.025) and patients with CD (p = 0.03), as well as with the BsmI polymorphism in patients with IBD (p = 0.04) and patients with CD (p = 0.04). A significant correlation was described between the degree of disease activity and genotypes for the FokI polymorphism in patients with UC (p = 0.027) and between the category of endoscopic lesions and genotypes for the Cdx2 polymorphism also in patients with UC (p = 0.046). Conclusions: The results suggest a potential correlation of VDR gene polymorphism with the chance of developing IBD, and the clinical course of the disease requires further studies in larger group of patients. Vitamin D supplementation should be recommended in both children with inflammatory bowel disease and in healthy peers. Full article

Piped drinking water supplies are exposed to a range of threats. Changing hazard situations arise from climate change, digitisation, and changing conditions in the power supply, among other things. Risk and crisis management adapted to the hazard situation can increase the resilience of the piped drinking water supply. Analogous to the risk management system, this article describes a methodology that ranges from hazard analysis with the prioritisation of 57 individual hazards to vulnerability assessment with the help of balance sheet structure models (BSM) and the planning and implementation of measures to increase the resilience of the piped drinking water supply in a targeted manner. The work steps mentioned build on each other and were tested using the case study of a water supply company in Saxony (Germany). As a result, priority hazards are identified, the remaining supply periods and replacement and emergency water requirements are determined as part of the vulnerability assessment, and finally, planning principles for increasing resilience are documented. The methodology focuses primarily on practicable application by water supply companies. Full article