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Search Results (2)

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Keywords = 20-hydroxyecdysterone

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35 pages, 4192 KiB  
Review
Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition
by Velislava Todorova, Stanislava Ivanova, Dzhevdet Chakarov, Krasimir Kraev and Kalin Ivanov
Nutrients 2024, 16(9), 1382; https://doi.org/10.3390/nu16091382 - 2 May 2024
Cited by 1 | Viewed by 8128
Abstract
The naturally occurring compounds ecdysterone and turkesterone, which are present in plants, including Rhaponticum carthamoides Willd. (Iljin), Spinacia oleracea L., Chenopodium quinoa Willd., and Ajuga turkestanica (Regel) Briq, are widely recognized due to their possible advantages for both general health and athletic performance. [...] Read more.
The naturally occurring compounds ecdysterone and turkesterone, which are present in plants, including Rhaponticum carthamoides Willd. (Iljin), Spinacia oleracea L., Chenopodium quinoa Willd., and Ajuga turkestanica (Regel) Briq, are widely recognized due to their possible advantages for both general health and athletic performance. The current review investigates the beneficial biological effects of ecdysterone and turkesterone in nutrition, highlighting their roles not only in enhancing athletic performance but also in the management of various health problems. Plant-based diets, associated with various health benefits and environmental sustainability, often include sources rich in phytoecdysteroids. However, the therapeutic potential of phytoecdysteroid-rich extracts extends beyond sports nutrition, with promising applications in treating chronic fatigue, cardiovascular diseases, and neurodegenerative disorders. Full article
(This article belongs to the Section Sports Nutrition)
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Figure 1

Figure 1
<p>PRISMA 2020 flow diagram [<a href="#B40-nutrients-16-01382" class="html-bibr">40</a>].</p>
Full article ">Figure 2
<p><span class="html-italic">Rhaponticum carthamoides</span> phytochemical composition and effects.</p>
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<p><span class="html-italic">Spinacia oleracea</span> nutrient profile and biological effects.</p>
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<p><span class="html-italic">Chenopodium quinoa</span> phytochemicals and biological effects.</p>
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13 pages, 2413 KiB  
Article
Development and Validation of High-Performance Liquid Chromatography for Identification and Quantification of Phytoecdysteroids Ecdysterone and Turkesterone in Dietary Supplements
by Velislava Todorova, Kalin Ivanov, Diana Karcheva-Bahchevanska and Stanislava Ivanova
Processes 2023, 11(6), 1786; https://doi.org/10.3390/pr11061786 - 12 Jun 2023
Cited by 6 | Viewed by 3537
Abstract
Phytoecdysteroids are a group of naturally occurring ecdysteroid hormones found in certain plant families and used for centuries for their adaptogenic, tonifying, and antioxidant properties. Ecdysterone and turkesterone are the dominant phytoecdysteroids found in the plant species Rhaponticum carthamoides Willd., Cyanotis arachnoidea C.B.Clarke [...] Read more.
Phytoecdysteroids are a group of naturally occurring ecdysteroid hormones found in certain plant families and used for centuries for their adaptogenic, tonifying, and antioxidant properties. Ecdysterone and turkesterone are the dominant phytoecdysteroids found in the plant species Rhaponticum carthamoides Willd., Cyanotis arachnoidea C.B.Clarke and Ajuga turkestanica (Regel) Briq., and have been recognized for their adaptogenic potential and ability to enhance physical performance. However, over the past few years, supplementation with ecdysterone by professional athletes has raised some concerns about its safety and quality, leading to its inclusion in the World Anti-Doping Agency monitoring program. This study proposes a simple and reliable method for quality control of ecdysterone- and turkesterone-containing products using high-performance liquid chromatography (HPLC) analysis. The HPLC method is based on reversed-phase chromatography and gradient elution to achieve a superior separation of phytoecdysteroids. The method has been shown to qualify both phytoecdysteroids at low concentrations such as 10.98 μg/mL for ecdysterone and 11.43 μg/mL for turkesterone. This method could be successfully used in research programs and routine quality control of dietary supplements to ensure their safety in professional athletes’ nutrition. Full article
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Graphical abstract

Graphical abstract
Full article ">Figure 1
<p>Chemical structures of ecdysterone and turkesterone.</p>
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<p>Effects of <span class="html-italic">R. carthamoides</span> extracts.</p>
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<p>(<b>A</b>) HPLC chromatogram of the standard solution of 20-hydroxyecdysone (25 μg/mL) with a retention time of 3.902 min. (<b>B</b>) HPLC chromatogram of the standard solution of turkesterone (25 μg/mL) with a retention time of 4.554 min. (<b>C</b>) HPLC chromatogram of the standard solutions of 20-hydroxyecdysterone and turkesterone.</p>
Full article ">Figure 4
<p>Calibration curves of 20-hydroxyecdysterone and turkesterone.</p>
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