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Open AccessReview
Recent Advancements in MXene-Based Biosensors for Health and Environmental Applications—A Review
by
Ashraf Ali
Ashraf Ali 1,2,
Sanjit Manohar Majhi
Sanjit Manohar Majhi 1,†,
Lamia A. Siddig
Lamia A. Siddig 1,†,
Abdul Hakeem Deshmukh
Abdul Hakeem Deshmukh 1,†,
Hongli Wen
Hongli Wen 3,
Naser N. Qamhieh
Naser N. Qamhieh 1,
Yaser E. Greish
Yaser E. Greish 4 and
Saleh T. Mahmoud
Saleh T. Mahmoud 1,*
1
Department of Physics, United Arab Emirates University, Al–Ain 15551, United Arab Emirates
2
Department of Physics, Khalifa University of Science and Technology, Abu Dhabi 127788, United Arab Emirates
3
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, China
4
Department of Chemistry, United Arab Emirates University, Al–Ain 15551, United Arab Emirates
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Biosensors 2024, 14(10), 497; https://doi.org/10.3390/bios14100497 (registering DOI)
Submission received: 18 September 2024
/
Revised: 5 October 2024
/
Accepted: 8 October 2024
/
Published: 12 October 2024
Abstract
Owing to their unique physicochemical properties, MXenes have emerged as promising materials for biosensing applications. This review paper comprehensively explores the recent advancements in MXene-based biosensors for health and environmental applications. This review begins with an introduction to MXenes and biosensors, outlining various types of biosensors including electrochemical, enzymatic, optical, and fluorescent-based systems. The synthesis methods and characteristics of MXenes are thoroughly discussed, highlighting the importance of these processes in tailoring MXenes for specific biosensing applications. Particular attention is given to the development of electrochemical MXene-based biosensors, which have shown remarkable sensitivity and selectivity in detecting various analytes. This review then delves into enzymatic MXene-based biosensors, exploring how the integration of MXenes with enzymes enhances sensor performance and expands the range of detectable biomarkers. Optical biosensors based on MXenes are examined, focusing on their mechanisms and applications in both healthcare and environmental monitoring. The potential of fluorescent-based MXene biosensors is also investigated, showcasing their utility in imaging and sensing applications. In addition, MXene-based potential wearable biosensors have been discussed along with the role of MXenes in volatile organic compound (VOC) detection for environmental applications. Finally, this paper concludes with a critical analysis of the current state of MXene-based biosensors and provides insights into future perspectives and challenges in this rapidly evolving field.
Share and Cite
MDPI and ACS Style
Ali, A.; Majhi, S.M.; Siddig, L.A.; Deshmukh, A.H.; Wen, H.; Qamhieh, N.N.; Greish, Y.E.; Mahmoud, S.T.
Recent Advancements in MXene-Based Biosensors for Health and Environmental Applications—A Review. Biosensors 2024, 14, 497.
https://doi.org/10.3390/bios14100497
AMA Style
Ali A, Majhi SM, Siddig LA, Deshmukh AH, Wen H, Qamhieh NN, Greish YE, Mahmoud ST.
Recent Advancements in MXene-Based Biosensors for Health and Environmental Applications—A Review. Biosensors. 2024; 14(10):497.
https://doi.org/10.3390/bios14100497
Chicago/Turabian Style
Ali, Ashraf, Sanjit Manohar Majhi, Lamia A. Siddig, Abdul Hakeem Deshmukh, Hongli Wen, Naser N. Qamhieh, Yaser E. Greish, and Saleh T. Mahmoud.
2024. "Recent Advancements in MXene-Based Biosensors for Health and Environmental Applications—A Review" Biosensors 14, no. 10: 497.
https://doi.org/10.3390/bios14100497
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