Asparagine and glutamine: co-conspirators fueling metastasis

M Luo, M Brooks, MS Wicha - Cell metabolism, 2018 - cell.com
M Luo, M Brooks, MS Wicha
Cell metabolism, 2018cell.com
Cancer cells frequently hijack normal metabolic pathways to promote their growth and
metastasis. Two recent papers by Knott et al.(2018) and Pavlova et al.(2018) demonstrate
that asparagine and glutamine work in concert to drive tumor growth and metastasis through
modulation of cell survival, growth, and EMT regulatory pathways.
Cancer cells frequently hijack normal metabolic pathways to promote their growth and metastasis. Two recent papers by Knott et al. (2018) and Pavlova et al. (2018) demonstrate that asparagine and glutamine work in concert to drive tumor growth and metastasis through modulation of cell survival, growth, and EMT regulatory pathways.
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