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Grm1tm1Dgen
Targeted Allele Detail
Summary
Symbol: Grm1tm1Dgen
Name: glutamate receptor, metabotropic 1; targeted mutation 1, Deltagen
MGI ID: MGI:3604591
Synonyms: Grm1tm1deltagen, T801
Gene: Grm1  Location: Chr10:10561803-10958100 bp, - strand  Genetic Position: Chr10, 3.44 cM, cytoband A2
Alliance: Grm1tm1Dgen page
Mutation
origin
Mutant Cell Line:  2972
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in the brain spinal cord, eye, heart, skin, tongue and testis; beta-galactosidase expression is detectable in the brain spinal cord, and eye but not in the heart, skin, tongue or testis.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 67 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Grm1 Mutation:  81 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory