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KEGG   Mirounga leonina (Southern elephant seal): 117998639
Entry
117998639         CDS       T07472                                 
Symbol
EP300
Name
(RefSeq) histone acetyltransferase p300 isoform X1
  KO
K04498  E1A/CREB-binding protein [EC:2.3.1.48]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx03083  Polycomb repressive complex
mlx03250  Viral life cycle - HIV-1
mlx04024  cAMP signaling pathway
mlx04066  HIF-1 signaling pathway
mlx04068  FoxO signaling pathway
mlx04110  Cell cycle
mlx04310  Wnt signaling pathway
mlx04330  Notch signaling pathway
mlx04350  TGF-beta signaling pathway
mlx04520  Adherens junction
mlx04630  JAK-STAT signaling pathway
mlx04720  Long-term potentiation
mlx04916  Melanogenesis
mlx04919  Thyroid hormone signaling pathway
mlx04922  Glucagon signaling pathway
mlx04935  Growth hormone synthesis, secretion and action
mlx05016  Huntington disease
mlx05152  Tuberculosis
mlx05161  Hepatitis B
mlx05164  Influenza A
mlx05165  Human papillomavirus infection
mlx05166  Human T-cell leukemia virus 1 infection
mlx05167  Kaposi sarcoma-associated herpesvirus infection
mlx05200  Pathways in cancer
mlx05203  Viral carcinogenesis
mlx05206  MicroRNAs in cancer
mlx05211  Renal cell carcinoma
mlx05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    117998639 (EP300)
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    117998639 (EP300)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    117998639 (EP300)
   04330 Notch signaling pathway
    117998639 (EP300)
   04350 TGF-beta signaling pathway
    117998639 (EP300)
   04630 JAK-STAT signaling pathway
    117998639 (EP300)
   04066 HIF-1 signaling pathway
    117998639 (EP300)
   04068 FoxO signaling pathway
    117998639 (EP300)
   04024 cAMP signaling pathway
    117998639 (EP300)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    117998639 (EP300)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    117998639 (EP300)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    117998639 (EP300)
   04935 Growth hormone synthesis, secretion and action
    117998639 (EP300)
   04919 Thyroid hormone signaling pathway
    117998639 (EP300)
   04916 Melanogenesis
    117998639 (EP300)
  09156 Nervous system
   04720 Long-term potentiation
    117998639 (EP300)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117998639 (EP300)
   05206 MicroRNAs in cancer
    117998639 (EP300)
   05203 Viral carcinogenesis
    117998639 (EP300)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    117998639 (EP300)
   05215 Prostate cancer
    117998639 (EP300)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117998639 (EP300)
   05161 Hepatitis B
    117998639 (EP300)
   05164 Influenza A
    117998639 (EP300)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117998639 (EP300)
   05165 Human papillomavirus infection
    117998639 (EP300)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    117998639 (EP300)
  09164 Neurodegenerative disease
   05016 Huntington disease
    117998639 (EP300)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mlx03000]
    117998639 (EP300)
   03036 Chromosome and associated proteins [BR:mlx03036]
    117998639 (EP300)
   03029 Mitochondrial biogenesis [BR:mlx03029]
    117998639 (EP300)
Enzymes [BR:mlx01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     117998639 (EP300)
Transcription factors [BR:mlx03000]
 Eukaryotic type
  Other transcription factors
   Pocket domain CBP
    117998639 (EP300)
Chromosome and associated proteins [BR:mlx03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    117998639 (EP300)
Mitochondrial biogenesis [BR:mlx03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Coactivators
    117998639 (EP300)
SSDB
Motif
Pfam: HAT_KAT11 KIX Creb_binding zf-TAZ RING_CBP-p300 Bromodomain ZZ KIX_2 Npa1 Med15_N
Other DBs
NCBI-GeneID: 117998639
NCBI-ProteinID: XP_034843328
Position
Unknown
AA seq 2434 aa
MKDCNTNSIPWSEVWKYLMLIKNKTEKFVILILSNSNFYLFSLLLDFGSLFDLEHDLPDE
LINSTELGLTNGGDISQLQTSLGIVQDAASKHKQLSELLRSGSSPNLNMGVGGPGQGMAS
QPQQNSPGLGLINSMVKSPMAQAGLTSPNMGMGTSGPNQGPTPSAAGMMNSPVNQPAMGM
NTGMNAGMNPGMLNAGNGQGMMPNQVMNGSIGAGRGRPNMQYPNPGMGNAGSLMTEPLQQ
GSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNSGQQIGAGGLGLQIQTKSVLPNNLS
PFAMDKKAVPGGGMPNMGQQQAPQVQQPGLVTPVAQGMGSGAHTADPEKRKLIQQQLVLL
LHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSGKSCQVAHCASSRQIISHWKN
CTRHDCPVCLPLKNAGDKRNQQSILTGAPVGLGNTSSLGVGQQSTPSLSTVSQIDPSSIE
RAYAALGLPYQVNQMPTQPQVQAKNQQNQQSGQSPQGMRPMSNMSASPMGVNGGVGVQTS
NLLSDSMLHSAINSQNPMMSENASVASLGPMPTAAQPSNTGIRKQWHEDITQDLRNHLVH
KLVQAIFPTPDPAALKDRRMENLVAYARKVEGDMYESANNRAEYYHLLAEKIYKIQKELE
EKRRTRLQKQNMLPSAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGNVPNQMMPR
ITPQPGLNQFGQMSMPQPPIGPRQTSPLQHHGQLAQPGTLNPPMGYGPRMQQPSNQSQFL
PQTQFSTQGMNVTNMPLAPSGGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPPLPQS
ALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATIPAPVPTPPAMPPGPPTQALHPPPRQTP
TPPPTQLPPPVQPSLAAAPSAEQPQQQPLPQQSAAASAPTPTAPLLPPQPSTPLSQPAVS
IEGQVSNPPSTSSTEVNSQTIPEKQPSQEVKMEAKMEVDPPEPADTQPEDIPETKAEDCK
MEPTETEERGTELKTETKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALY
RQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFN
NAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIP
RDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVE
CTECGRKMHQICVLHHEIIWPSGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRV
NDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEI
DGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVK
KLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDI
FKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSK
NAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAA
NSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRF
VYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNSQQAAATQS
PGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLI
ALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQG
LPSPTPATPTTPTGQQPATPQTPQPPPAAQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ
VTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPQMTPMAP
MSMNPPPMARGPSGHLEPGMGPTGMQQQPQWVQGGLPQPQQLQPGMQRPAMMSVAQHGQP
LNIAPQPGLGQVGVSPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAF
IKQRAAKYASSNPQPLPGQPGMPQGQPGLQPPAMPGQQGVHSNAAMPNMNPMPAGVQRAG
LPPQPPPQQLQPPMGGMSPQGQQMNMNHNAMPSQFRDILRRQQMMQQQQQGAGPGIGPGM
ANHNQFQQPQGVGYPPPPPQPQPQPRMQHHMQQMQQGSLGQMGQLPQALGAEAGASLQAY
QQRLLQQQMGSPAQPNPMSPQQHMLPSQAQSPHLQGQQIPSSLSNQVRSPQPVPSPRPQS
QPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQSSMLSQLASNP
GMANLHGASATDLGLSTDNSDLNSNLSQSTLDIH
NT seq 7305 nt   +upstreamnt  +downstreamnt
atgaaagactgcaatacaaatagtatcccatggagtgaggtttggaaatatttaatgctt
atcaagaacaaaacagagaaatttgtgattttgattctgtcaaactctaacttttatctt
ttctctttgcttttagattttggctctctgtttgatttggagcatgacttaccagatgaa
ttaatcaactctacagaattgggactaaccaatggtggtgatattagtcagcttcagaca
agtcttggcatagtacaagatgcagcctctaaacataaacaactgtcagaattgctccgg
tctggtagttcccctaacctcaatatgggggttggtggcccaggccaaggcatggccagc
cagccccaacagaatagtcctggattaggtttgataaatagcatggttaaaagcccaatg
gcacaggcaggcttgacttctcccaacatggggatgggcactagtggaccaaatcagggt
cctacgccatctgcagcaggtatgatgaacagtccagtaaatcaacctgccatgggaatg
aacacagggatgaatgctggcatgaatcctggaatgttgaatgcaggcaatggacagggg
atgatgcctaatcaagtcatgaacggttcaattggagcaggccgggggcgacctaatatg
cagtacccaaacccaggcatgggaaatgctggcagtttaatgaccgagccactgcagcaa
ggctctcctcagatgggaggacaaacaggattgagaggccctcagcctcttaagatggga
atgatgaacaaccctaatccttatggttcaccatacactcagaattctggacagcagatt
ggagctggtggccttggtctccagattcagacaaagtctgtactaccaaataacttatct
ccatttgcaatggacaaaaaggcagttcctggtggaggaatgcccaacatgggtcaacag
caggccccacaggtccagcagccaggccttgtgactccagtagcccaagggatgggttct
ggagcgcatacagctgatccagagaagcgcaagctcatccagcagcagcttgttctcctt
ttgcatgctcacaagtgccagcgccgggagcaggctaatggggaagtgaggcagtgcaac
cttccccactgtcgcacaatgaagaacgtcctaaaccacatgacacactgccagtcaggc
aagtcctgccaagtggcacactgtgcttcttctcgacaaatcatttcacactggaagaat
tgtacaaggcatgattgtcctgtgtgtctcccccttaaaaatgctggagataagagaaac
caacagtcaattctgactggagcaccagttggacttggaaatactagctctctaggggtg
ggtcaacagtctacccccagcctaagcactgttagtcagattgatcccagctctatagaa
agggcgtatgcagctcttgggctgccctatcaagtaaatcaaatgccgacgcagccccag
gtgcaagcaaagaaccagcagaatcagcagtctgggcaatctccccaaggcatgcgaccc
atgagcaacatgagtgctagtcctatgggagtaaatggaggtgtaggggttcaaacgtcg
aatcttctttctgactcaatgttgcattcagccataaattctcaaaatccaatgatgagt
gaaaatgccagtgtggcctccctgggtcctatgccaacagcagctcaaccatccaatact
ggaattcggaaacaatggcatgaagatattactcaggatcttcgaaatcatcttgttcac
aaacttgttcaagccatatttcctactccggatcctgctgctttaaaagacagacggatg
gaaaacttagttgcatacgcccggaaagtggaaggggacatgtatgaatctgcaaataat
cgagcggaatactaccacctgctagctgagaagatctataagatccagaaagaactagaa
gaaaaacgaaggactagactacagaaacaaaacatgctgcctagtgctgcaggcatggtg
ccagtttctatgaatccagggcccaatatggggcagccacaaccaggaatgacttccaat
ggccctctacctgacccatctatgatccgtggcaatgtgccaaaccagatgatgcctcgg
ataactccacagcctggtttgaatcagtttggccagatgagtatgccccagcccccaatt
ggaccccggcaaacctctcctcttcagcaccatggacagttagctcagcctggaactctc
aacccacctatgggctatgggcctcgcatgcagcagccttccaaccagagccagttcctt
ccccagactcagttctcaacacagggaatgaatgtaacgaatatgcctttggctccgtct
ggcgggcaagcaccagtatcccaagcacaaatgtccagttcttcctgccctgtgaactct
cctataatgcctccagggtctcaagggagccacattcactgtccccctctccctcagtca
gctctgcatcagaattcaccctctccagtacctagtcgcacccctacgcctcaccacact
cccccaagcataggggctcagcagccaccagcaacaattccagcccctgttcctacacct
ccagccatgccacctgggccaccgacccaggccctccatccacctccgaggcagacgcct
actccaccgccgacgcagcttcctcctccagttcagccttcgcttgctgctgcgccttca
gccgagcagccgcagcagcagcctcttccacagcagagcgccgcggcatcggcccccacc
ccgaccgcgccactgctgcccccacagccttcgactccgctttcccaaccagctgtaagc
atcgaagggcaggtatcaaacccaccatccactagtagcacagaagtgaattctcagacc
attcctgagaagcagccttcacaggaagtgaaaatggaggcaaagatggaagtggatcca
ccagaaccagccgatactcagccagaggatattccagagactaaagcagaagactgtaaa
atggaacctacagaaacagaagagagaggcactgaattaaaaactgaaacaaaagaggag
gaagaccagccaagtacttcagctacccagtcatctccagccccaggacagtcaaagaag
aagattttcaaaccagaagagttacgacaggcactgatgccaactttggaggcactttac
cgacaggatccagaatcccttccctttcgtcaacctgtggaccctcaacttcttggaatc
cctgattactttgatattgtgaagagccccatggacctttctaccatcaagaggaagtta
gacactggacagtatcaggagccctggcagtatgtggatgacatttggcttatgttcaac
aatgcctggttgtataatcggaaaacatctcgggtatacaaatactgctccaagctgtct
gaagtctttgaacaagaaattgacccagtaatgcaaagccttggatattgttgtggcaga
aagttggagttctctccacagacactctgttgctatggcaaacagttatgcacaatccct
cgtgatgccacttactacagttaccagaacaggtatcatttctgtgagaagtgtttcaat
gaaatccaaggggagagcgtttctttgggggatgacccttcccagcctcaaactacaata
aataaagaacaattttccaagagaaaaaatgacacactggatcctgaactgtttgttgaa
tgtacagagtgtggaagaaagatgcatcagatctgtgtccttcatcatgaaatcatctgg
ccatctggatttgtctgtgatggctgcttaaagaaatctgcacgaaccaggaaagaaaat
aagttttctgctaaaaggttgccatccaccaggcttggtacctttctggagaatcgtgtg
aatgactttcttaggcgacagaatcaccctgagtcaggagaggtcactgttcgggtagtt
catgcttctgacaaaactgtggaagtgaaaccaggcatgaaagcaaggtttgtagatagt
ggagagatggcagaatcctttccataccgaaccaaagccctctttgcctttgaagagata
gacggtgttgacttgtgcttctttggcatgcatgttcaagagtatggctctgactgccct
ccacccaaccagaggagagtttacatatcataccttgacagtgttcatttcttccgtcct
aaatgcttgaggactgcagtctatcatgaaattctaattggatatttagaatacgtcaag
aaactaggatatacaacagggcatatttgggcttgtcccccaagtgagggagacgactat
atcttccattgccatcctcctgaccagaagatacccaagcccaagcgactgcaggagtgg
tacaaaaagatgcttgacaaggccgtgtctgagcgaatcgtccatgactacaaggatatt
tttaaacaagctactgaagatcgattaacaagtgcaaaggagttgccttactttgagggt
gatttctggcccaatgttctggaagagagcattaaggaactggaacaggaggaggaagag
cgaaagcgagaagaaaacaccagcaacgagagcacagatgtgacaaagggagatagcaaa
aatgctaaaaagaaaaataataagaaaaccagcaaaaacaagagcagcctgagtaggggc
aacaagaagaagccaggcatgcccaatgtatccaatgacctctcgcagaaactgtatgcc
acgatggagaaacacaaagaggtcttctttgtgatccgtctcatcgctggccctgccgcc
aactccctgcctcccatcgtcgatcctgaccccctcatcccctgcgatctgatggatggg
cgggacgccttcctaaccctcgcaagggacaagcacctggagttctcttcacttcgaaga
gcccagtggtccaccatgtgcatgctggtggagctgcacacccagagccaggaccgcttc
gtctacacctgcaacgagtgcaagcaccatgtggagacacgctggcactgcactgtctgc
gaggattatgatttgtgcatcacctgctacaacactaaaaaccacgaccacaagatggag
aaactaggcctcgggttagatgacgagagcaacagccagcaggctgcggccacccagagc
ccgggagactcgcggcgcctgagcatccagcgctgcatccagtccctggtgcacgcctgc
cagtgccgcaacgccaactgctcgctgccgtcctgccagaagatgaagcgggtggtgcag
cacaccaagggctgcaagcgcaagaccaacggcggctgccccatctgtaagcagctcatc
gccctctgctgctaccacgccaagcactgccaggagaacaagtgcccggtgcccttctgc
ctcaacatcaagcagaagctccggcagcagcagctgcagcaccggctccagcaggcccag
atgctccgcaggaggatggccagcatgcagcggaccggtgtggtggggcagcagcagggc
ctgccctccccgactcctgccacccccaccacgccgacgggccagcagccagccacgccg
cagacgccccagcccccacctgccgctcagcctcagcccacccctcccaacagcatgccg
ccctacttgcccaggactcaggctgctggccctgtctcccagggcaaggcggcgggccag
gtgacgcctcccaccccccctcagactgctcagccacccctgccggggcccccgcctgcc
gcggtggaaatggccatgcagattcagagggcagctgagacgcagcgccagatggcccac
gtgcaaatttttcaaaggccgatccagcaccagatgccccagatgactccgatggccccc
atgagtatgaacccaccccctatggccagaggtcccagtgggcacttggagccagggatg
gggcccacagggatgcagcaacagccacagtgggtccaaggaggattgcctcagccccag
cagctacagcctgggatgcagaggccagccatgatgtcagtggcccagcatggtcagccc
ttgaatatagctccgcagccaggactgggccaggtaggcgtgagccctctcaaaccaggc
actgtgtctcaacaagccttacaaaaccttttgcggactctcaggtctcccagctccccc
ctacagcagcaacaggtgcttagtatccttcacgccaacccccagctgttggctgcgttc
atcaagcagcgggctgccaagtatgccagctcgaatccgcagcccctccctgggcagcct
ggcatgccccagggccagccggggctgcagccgcctgccatgccaggccagcagggggtc
cactctaacgcagccatgccgaacatgaaccccatgccagcgggcgtccagagggccggc
ctgcccccccagccgccgccgcagcagctccagccgcccatgggagggatgagcccccaa
ggccagcagatgaacatgaaccacaacgccatgccttcgcagttccgagacatcttgagg
cggcagcagatgatgcagcagcagcagcagggagcggggcccggaatcgggcccgggatg
gccaaccataaccagttccagcagccccagggagttggctacccgccgccgccgccccag
ccgcagccgcagccgcgcatgcagcatcacatgcagcagatgcagcaagggagcctgggg
cagatgggccagctcccccaggccttgggagcagaggcaggagccagcctgcaggcgtat
cagcaacgactcctccagcaacagatggggtcccctgctcagcccaaccccatgagcccc
cagcagcatatgctcccgagccaggctcagtccccacacctccaaggccagcagatccct
tcttctctctccaatcaagtgcgttctccccagcccgtcccttctccgcggccgcagtcc
cagcccccccactccagcccttccccaaggatgcagcctcagccttctccacaccacgtt
tccccacagaccagttctccacaccctggactggtagctgcccaggccaaccccatggaa
caagggcattttgccagcccggaccagagttcaatgctgtctcagctcgctagcaatcca
ggcatggcaaacctccatggtgcaagcgccacggacctgggactcagcaccgataactca
gacttgaattcaaacctctcacagagtacactagacatacactag

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (28)   
   KEGG PATHWAY (28)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (10)   
   Pfam (10)   
All databases (52)   

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