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KEGG   VARIANT: 596v1
Entry
596v1                      Variant                                 
Name
BCL2 overepression
Gene
BCL2  BCL2 apoptosis regulator [KO:K02161]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
overexpression
Network
nt06231  Apoptosis (cancer)
nt06267  Small cell lung cancer
nt06524  Apoptosis
Disease
H00013  Small cell lung cancer
Drug target
Venetoclax: D10679<JP/US>
Reference
  Authors
Shivapurkar N, Reddy J, Chaudhary PM, Gazdar AF.
  Title
Apoptosis and lung cancer: a review.
  Journal
J Cell Biochem 88:885-98 (2003)
DOI:10.1002/jcb.10440
Reference
  Authors
Junker K, Wiethege T, Muller KM
  Title
Pathology of small-cell lung cancer.
  Journal
J Cancer Res Clin Oncol 126:361-8 (2000)
DOI:10.1007/PL00008483
Reference
PMID:8261463
  Authors
Ikegaki N, Katsumata M, Minna J, Tsujimoto Y
  Title
Expression of bcl-2 in small cell lung carcinoma cells.
  Journal
Cancer Res 54:6-8 (1994)

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