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KEGG   Danio rerio (zebrafish): 403063
Entry
403063            CDS       T01004                                 
Symbol
araf
Name
(RefSeq) serine/threonine-protein kinase A-Raf
  KO
K08845  A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04010  MAPK signaling pathway
dre04012  ErbB signaling pathway
dre04068  FoxO signaling pathway
dre04270  Vascular smooth muscle contraction
dre04810  Regulation of actin cytoskeleton
dre04910  Insulin signaling pathway
dre04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:dre00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    403063 (araf)
   04012 ErbB signaling pathway
    403063 (araf)
   04068 FoxO signaling pathway
    403063 (araf)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    403063 (araf)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    403063 (araf)
   04914 Progesterone-mediated oocyte maturation
    403063 (araf)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    403063 (araf)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dre01001]
    403063 (araf)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     403063 (araf)
Protein kinases [BR:dre01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   403063 (araf)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase RBD C1_1 Kinase-like zf-RING-like Pkinase_fungal ABC1 Kdo TUG-UBL1
Other DBs
NCBI-GeneID: 403063
NCBI-ProteinID: NP_991306
ZFIN: ZDB-GENE-050102-2
Ensembl: ENSDARG00000054533
UniProt: Q75Y03
Position
5:26853069..26869389
AA seq 608 aa
MSNTSSCSSSGETSPDDTPRGGGTIRVYLPNKQRTVVNVRPGQTVYDSLDKALKVRGLSQ
DCCAVFRLLEGRKRLTEWDTDITPLVGEELLVEVLDDVPLTMHNFVRKTFFKLAYCDFCH
KFLFNGFRCQTCGYKFHQHCSSKVPTVCVDMDTMTKRCVNNTEDCPAILIYPATNSISQS
DLPLTSDSPGGELPSSPSNFCLFIRGEDGQSLQRHRSTSTPNVHMVSTLEPGAAGLLEEP
FKISTVASYTGYESSPKPSTSPPHLGSPGRKPPKSPSEPKERKQSSSDDKKKVHRGGYRD
SSYYWEVHPREVSMLKRIGAGSFGTVFKGKWHGDVAIKILKVTEPTPEQLQAFKNEMQVL
RKTRHVNILLFMGFMTRPNFAIITQWCEGSSLYRHLHVTETKFDTMRRIDVARQTAQGMD
YLHAKNIIHRDLKSNNIFLHEGWTVKIGDFGLATVKSRWSGSQQVEQPSGSILWMAPEVI
RMQDTNPYTFQSDVYGYGVVLYELMSGTLPYSNINNRDQIIFMVGRGYLSPDLSKLYSNC
PKSMKRLIIDCLKFKRDERPLFPQILVSIEQVQELLPKIERSASEPSLHRAVHAEDLNPL
LLHTTRFL
NT seq 1827 nt   +upstreamnt  +downstreamnt
atgtccaacacttcctcctgttcctcctcgggggaaaccagcccggacgatacaccccga
ggtggaggcaccatccgcgtctacctccctaacaagcagcggacggtggtaaacgttcgg
cctgggcaaactgtgtatgatagtttagataaagccctaaaagtccgaggcctaagccag
gattgctgtgctgtctttcgcctgcttgaaggccggaagagacttacagaatgggacact
gacatcacacccctcgtgggggaagagctactggtagaagtcctggatgatgttcccctt
accatgcacaactttgtacgtaaaacgttctttaagttagcatactgtgacttctgccac
aagttcttattcaacggcttcaggtgtcagacatgtggatataaatttcaccagcactgc
agcagtaaagtccctacagtatgtgtggacatggacacaatgacaaaacggtgtgttaat
aatacagaagactgccctgcgatattgatatatccggccaccaattccatatcgcagagc
gacctacctttaacctcagattctcctggaggggagctgccgtcttccccgtcaaacttc
tgtttgttcattcgaggagaggacggtcagtctctccagaggcatcgatcaacctcaaca
cccaatgttcacatggtcagcacgctggagcctggcgctgctggccttttggaggagcca
ttcaaaatcagcacagtggcgtcctacacagggtacgagtcctctcccaaaccttccact
agcccaccccacctagggtcgccaggaagaaaaccccccaaatccccttctgaacccaag
gaacgaaagcagtcctcgtctgatgataaaaagaaagtgcaccggggaggttacagagac
tccagttactactgggaggtgcacccgcgggaggtgtccatgttaaagaggattggagca
ggctcttttgggaccgtctttaaaggcaagtggcatggagacgtggccatcaaaattctt
aaagtgacagagcccacaccggagcagctccaggcctttaaaaatgagatgcaggtttta
cgaaaaacacgccatgtaaacattctgctgtttatgggcttcatgacaaggcctaatttt
gccattatcacacagtggtgtgaaggcagcagtctgtatcgccatctgcatgtcactgag
accaagtttgacaccatgcggcgcattgatgttgctcgccaaacagcacagggcatggat
tatcttcacgccaagaatatcattcatcgggacttgaaatctaataatatcttcctgcat
gaaggctggacagtaaaaatcggtgactttggcttggctacagtaaagtctcgctggagt
ggctcacagcaggtcgaacagcccagtggctccatcctgtggatggctcctgaggtgatc
agaatgcaagacactaacccgtacaccttccagtctgatgtgtatggatatggagtggtg
ctctacgaactgatgtctgggactttgccttattcgaatatcaacaaccgcgatcagatt
attttcatggtgggtcgtggttacttgtctccagacctcagtaaattatacagtaactgc
ccgaaatcaatgaagaggctcatcattgactgtctgaaattcaaacgggatgaacggcct
ctctttccacagatcctggtgagcattgagcaggtccaggaattgttgccaaaaatcgag
cggagtgcctctgagccctctctacaccgtgctgtacatgccgaggacctgaatccgctt
ctccttcacaccacgcgcttcctgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
Protein domain (10)   
   Pfam (10)   
All databases (62)   

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