Entry |
|
Name |
NLRP3 inflammasome signaling pathway
|
Definition |
(NLRP3+PYCARD) -> CASP1 -> (IL1B,IL18,IL33) |
Expanded |
(114548+29108) -> 834 -> (3553,3606,90865) |
Class |
|
Type |
Reference
|
Pathway |
hsa04621 | NOD-like receptor signaling pathway |
|
Gene |
114548 | NLRP3; NLR family pyrin domain containing 3 |
29108 | PYCARD; PYD and CARD domain containing |
3553 | IL1B; interleukin 1 beta |
3606 | IL18; interleukin 18 |
90865 | IL33; interleukin 33 |
|
Reference |
|
Authors |
Rathinam VA, Vanaja SK, Fitzgerald KA |
Title |
Regulation of inflammasome signaling. |
Journal |
|
Reference |
|
Authors |
Coll RC, O'Neill L, Schroder K |
Title |
Questions and controversies in innate immune research: what is the physiological role of NLRP3? |
Journal |
|