Entry |
|
Name |
RIG-I-NFKB signaling pathway
|
Definition |
RNA -> RIGI -> MAVS -> IKK -> NFKBIA -> NFKB => (IFNA,IFNB1) |
Expanded |
C00046 -> 23586 -> 57506 -> (1147+3551+8517) -> 4792 -> (4790+5970) => ((3439,3440,3441,3442,3443,3444,3445,3446,3447,3448,3449,3451,3452),3456) |
Class |
|
Type |
Reference
|
Pathway |
hsa04622 | RIG-I-like receptor signaling pathway |
|
Gene |
23586 | RIGI; RNA sensor RIG-I |
57506 | MAVS; mitochondrial antiviral signaling protein |
1147 | CHUK; conserved helix-loop-helix ubiquitous kinase |
3551 | IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta |
8517 | IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma |
4792 | NFKBIA; NFKB inhibitor alpha |
4790 | NFKB1; nuclear factor kappa B subunit 1 |
5970 | RELA; RELA proto-oncogene, NF-kB subunit |
3439 | IFNA1; interferon alpha 1 |
3440 | IFNA2; interferon alpha 2 |
3441 | IFNA4; interferon alpha 4 |
3442 | IFNA5; interferon alpha 5 |
3443 | IFNA6; interferon alpha 6 |
3444 | IFNA7; interferon alpha 7 |
3445 | IFNA8; interferon alpha 8 |
3446 | IFNA10; interferon alpha 10 |
3447 | IFNA13; interferon alpha 13 |
3448 | IFNA14; interferon alpha 14 |
3449 | IFNA16; interferon alpha 16 |
3451 | IFNA17; interferon alpha 17 |
3452 | IFNA21; interferon alpha 21 |
3456 | IFNB1; interferon beta 1 |
|
Metabolite |
|
Reference |
|
Authors |
Xie P |
Title |
TRAF molecules in cell signaling and in human diseases. |
Journal |
|
Reference |
|
Authors |
Mu Y, Li M, Ding F, Ding Y, Ao J, Hu S, Chen X |
Title |
De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea) and analysis of the immune relevant genes and pathways involved in the antiviral response. |
Journal |
|
Reference |
|
Authors |
Arnoult D, Carneiro L, Tattoli I, Girardin SE |
Title |
The role of mitochondria in cellular defense against microbial infection. |
Journal |
|
Reference |
|
Authors |
Jensen S, Thomsen AR |
Title |
Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion. |
Journal |
|