| Entry |
|
|---|
| Name |
Rivoceranib (USAN/INN);
Apatinib |
|---|
| Formula |
C24H23N5O
|
|---|
| Exact mass |
397.1903
|
|---|
| Mol weight |
397.47
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG02966 Rivoceranib
D11288 Rivoceranib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
VEGFR family
VEGFR2 (KDR)
D11288 Rivoceranib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG02966 Rivoceranib
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 30
1 C8y C 15.4700 -18.3400
2 C8x C 14.2100 -19.0400
3 C8x C 13.0200 -18.2700
4 C8y C 13.0200 -16.9400
5 C8x C 14.2100 -16.2400
6 C8x C 15.4700 -16.9400
7 N1b N 11.8300 -16.1700
8 C5a C 10.5700 -16.8700
9 O5a O 10.5700 -18.2700
10 C8y C 9.3800 -16.1700
11 C8y C 8.1900 -16.8700
12 N5x N 7.0000 -16.1700
13 C8x C 7.0000 -14.7700
14 C8x C 8.1900 -14.0700
15 C8x C 9.3800 -14.7700
16 N1b N 8.1900 -18.2700
17 C1b C 6.9776 -18.9700
18 C8y C 5.7821 -18.2796
19 C8x C 5.7820 -16.8703
20 C8x C 4.5696 -16.1703
21 N5x N 3.3572 -16.8703
22 C8x C 3.3572 -18.2797
23 C8x C 4.5696 -18.9796
24 C1z C 16.6757 -19.0514
25 C1x C 16.6901 -20.4397
26 C1x C 18.0149 -20.8550
27 C1x C 18.8193 -19.7234
28 C1x C 17.9916 -18.6087
29 C3b C 16.6766 -17.6500
30 N3a N 16.6766 -16.2500
BOND 33
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 8 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 10 15 1
17 11 16 1
18 16 17 1
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 18 23 1
26 1 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 24 28 1
32 24 29 1
33 29 30 3
|
|---|
