Entry |
|
Name |
Pramocaine (INN) |
Formula |
C17H27NO3
|
Exact mass |
293.1991
|
Mol weight |
293.40
|
Structure |
|
Simcomp |
|
Remark |
|
Efficacy |
Anesthetic (local) |
Target |
|
Pathway |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AD Local anesthetics
C05AD07 Pramocaine
D08407 Pramocaine (INN)
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AB Anesthetics for topical use
D04AB07 Pramocaine
D08407 Pramocaine (INN)
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D08407 Pramocaine (INN)
SCN2A
D08407 Pramocaine (INN)
SCN3A
D08407 Pramocaine (INN)
SCN4A
D08407 Pramocaine (INN)
SCN5A
D08407 Pramocaine (INN)
SCN8A
D08407 Pramocaine (INN)
SCN9A
D08407 Pramocaine (INN)
SCN10A
D08407 Pramocaine (INN)
SCN11A
D08407 Pramocaine (INN)
|
Other DBs |
|
KCF data |
ATOM 21
1 C8y C 24.2200 -18.3400
2 C8x C 24.2200 -19.7400
3 C8x C 22.9600 -17.6400
4 O2a O 25.4100 -17.6400
5 C8x C 22.9600 -20.4400
6 C8x C 21.7700 -18.3400
7 C1b C 26.6000 -18.3400
8 C8y C 21.7700 -19.7400
9 C1b C 27.8600 -17.6400
10 O2a O 20.5800 -20.4400
11 C1b C 29.0500 -18.2700
12 C1b C 19.3200 -19.7400
13 N1y N 30.2400 -17.5700
14 C1b C 18.1300 -20.4400
15 C1x C 31.4300 -18.2700
16 C1x C 30.2400 -16.1700
17 C1b C 16.9400 -19.7400
18 C1x C 32.6900 -17.5700
19 C1x C 31.4300 -15.4700
20 C1a C 15.6800 -20.4400
21 O2x O 32.6900 -16.1700
BOND 22
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 3 6 1
6 4 7 1
7 5 8 1
8 7 9 1
9 8 10 1
10 9 11 1
11 10 12 1
12 11 13 1
13 12 14 1
14 13 15 1
15 13 16 1
16 14 17 1
17 15 18 1
18 16 19 1
19 17 20 1
20 18 21 1
21 6 8 2
22 19 21 1
|