Quetiapine Alternatives Compared
Quetiapine | Caplyta | Lybalvi |
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Quetiapine | Caplyta (lumateperone) | Lybalvi (olanzapine / samidorphan) |
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Prescription only
Quetiapine is an antipsychotic that calms and sedates, helping to relieve psychotic thoughts and manic and depressive behavior. Sedation, low blood pressure, and weight gain are common side effects... View more |
Prescription only
Caplyta is an atypical antipsychotic that may be used to treat adults with schizophrenia. Sedation is the most common side effect and it should not be used in people with moderate to severe liver... View more |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide. |
Related suggestions Schizophrenia
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More about Quetiapine | More about Caplyta (lumateperone) | More about Lybalvi (olanzapine / samidorphan) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Quetiapine has an average rating of 7.2 out of 10 from a total of 2205 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
Caplyta has an average rating of 6.4 out of 10 from a total of 172 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 31% reported a negative effect. |
Lybalvi has an average rating of 8.5 out of 10 from a total of 12 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 0% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: quetiapine side effects in more detail. |
See also: Caplyta side effects in more detail. |
See also: Lybalvi side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all quetiapine prices |
View all Caplyta prices |
View all Lybalvi prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Seroquel, Seroquel XR |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
6 hours |
18 hours |
54 hours (empirically) |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 716 drugs are known to interact with quetiapine:
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A total of 596 drugs are known to interact with Caplyta:
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A total of 696 drugs are known to interact with Lybalvi:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
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First Approval Date | ||||||||||||||||||||||||||
September 26, 1997 |
December 20, 2019 |
May 28, 2021 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.