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In-vitro scavenging activity and fractions of Lophira

In-vitro scavenging activity and fractions of Lophira

2016
ISAAC  ASIEDU-GYEKYE
Abstract
The present study aims at fractions of acetate fraction. Petroleum ether, dichloromethane, ethyl acetate, butanol and water fractions were prepared from the methanol extract of the plant. The scavenging picrylhydrazyl), the total phenolic (T fractions were determined by spectrophotometrical quercetin (Qu) as reference antioxidant. percent effective extract and fractions. An ethyl acetate fraction of the plant was conducted in female Albino rats OECD(420) Guidelines analysis. Histopathological examinations of the heart, kidney and The results showed that the ethylacetate fraction of scavenging activity of highest amount of total phenols (14,4±0,02 flavonoids (93,3±0,04mg of Qu equivalent/g of plant fraction)as and ascorbic acid (IC lipid profile didn’t show any major change compared to the control group. However, a significant increase of aminotransferase of experiment.

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