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Study of serum ghrelin and resistin levels and their correlation with zinc and magnesium in men with type 2 diabetes

Study of serum ghrelin and resistin levels and their correlation with zinc and magnesium in men with type 2 diabetes

GSC Advanced Research and Reviews
Abstract
Introduction: The objectives of our work were to compare the serum concentrations of lipid parameters,insulin, resistin, ghrelin, zinc and magnesium between two groups of men with obese type 2 diabetes and a control group and to study possible correlations between these differentparameters. Material and methods: This was a monocentric case-control study during the period 19 October 2015 to 18 November 2015. It included biological parameters from two separate samples: a group of 41 male, obese, type 2 diabetic patients and a group of 34 diabetes-free controls. Results: Mean plasma ghrelin concentrations were significantly lower in patients with type 2 diabetes compared to those in the control group: (14.05 ± 2.35 pg/mL) versus (45.45 ± 13.59 pg/mL). Mean resistance was significantly higher in diabetics (10.09 ± 2.63 ng/mL) compared to healthy subjects (2.22 ± 0.58 ng/mL). In multivariate analysis, body mass index (BMI) and insulin levels were factors that could influence zincemia var...

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