A 61-year-old woman presented with a 16 cm retroperitoneal sarcoma, which demanded a multispecialist effort. There was adherence to the left ureter, the iliac vessels, the mesosigmoideum and the small intestine. After angiographic embolization, the tumor, sigmoid colon and left ureter were excised. Histology, immunohistology and electron microscopy gave the diagnosis pleomorphic sarcoma. The microscopic radicality was doubtful, but we abstained from adjuvant radiotherapy due to the large field and risk of toxicity. The patient remains disease-free after 24 months.
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