Poster: "ECR 2015 / C-1894 / Preoperative lymph node staging in patients with primary prosta... more Poster: "ECR 2015 / C-1894 / Preoperative lymph node staging in patients with primary prostate cancer: usefulness of diffusion-weighted MR imaging at 3T-device" by: "S. Ortori, P. Boraschi, V. Vallini, F. Manassero, M. Gabelloni, C. Selli, C. Bartolozzi; Pisa/IT"
Poster: "ECR 2013 / C-0799 / Evaluation of pelvic lymph nodes in patients with prostate canc... more Poster: "ECR 2013 / C-0799 / Evaluation of pelvic lymph nodes in patients with prostate cancer: usefulness of 3T Diffusion Weighted MR Imaging (DW-MRI)" by: "V. Vallini1, S. Ortori2, P. Boraschi2, V. Zampa2, F. Manassero2, C. Selli2, C. Bartolozzi2; 1Bellinzona/CH, 2Pisa/IT"
PURPOSE Our study was aimed to assess the diagnostic value of MR cholangiopancreatography (MRCP) ... more PURPOSE Our study was aimed to assess the diagnostic value of MR cholangiopancreatography (MRCP) and MR imaging at 3 T device when evaluating biliary adverse events after liver transplantation. MATERIALS AND METHODS A series of 384 MR examinations in 232 liver transplant subjects with suspected biliary complications (impaired liver function tests and/or biliary abnormalities on ultrasound) were performed at 3 T device (GE-DISCOVERY MR750; GE Healthcare). After the acquisition of axial 3D dual-echo T1-weighted images and T2-weighted sequences (propeller and SS-FSE), MRCP was performed through coronal thin-slab 3D-FRFSE and coronal oblique thick-slab SSFSE T2w sequences. DW-MRI of the liver was performed using an axial spin-echo echo-planar sequence with multiple b values (150, 500, 1000, 1500 s/mm2) in all diffusion directions. Contrast-enhanced MRCP was performed in 25/232 patients. All MR images were blindly evaluated by two experienced abdominal radiologists in consensus to determine the presence of biliary complications, whose final diagnosis was based on direct cholangiography, surgery and integrating clinical follow-up with ultrasound and/or MRI findings. RESULTS In 113 patients no biliary abnormality was observed. The remaining 119 subjects were affected by one or more of the following complications: non-anastomotic strictures including typical ischemic-type biliary lesions (n = 67), anastomotic strictures (n = 34), ampullary dysfunction (n = 4), anastomotic leakage (n = 4), stones, sludge and casts (n = 65), vanishing bile duct (n = 1). The sensitivity, specificity, PPV, NPV and diagnostic accuracy of the reviewers for the detection of all types of biliary complications were 99%, 96%, 95%, 99% and 97%, respectively. CONCLUSION MR cholangiopancreatography and MR imaging at 3 T device are extremely reliable for detecting biliary complications after liver transplantation.
Poster: "ECR 2010 / C-0024 / Ischemic-type biliary lesions following liver transplantation: ... more Poster: "ECR 2010 / C-0024 / Ischemic-type biliary lesions following liver transplantation: Evaluation with Gd-EOB-DTPA-enhanced MR cholangiography" by: "P. Boraschi, F. Donati, R. Gigoni, S. Salemi, F. Filipponi, C. Bartolozzi, F. Falaschi; Pisa/IT"
ABSTRACT Purpose: To present diffusion and perfusion magnetic resonance imaging (MRI) characteris... more ABSTRACT Purpose: To present diffusion and perfusion magnetic resonance imaging (MRI) characteristics of focal nodular hyperplasia (FNH) of the liver. Materials and methods: Thirty-five patients with 52 FNHs (21 were pathologically-confirmed) underwent MRI at 1.5-T device. MR diffusion [diffusion-weighted imaging (DWI)] was performed using a free-breathing single-shot, spin-echo, echo-planar sequence with b gradient factor value of 500 s/mm². MR perfusion [perfusion-weighted imaging (PWI)] consisted of a 3D free-breathing LAVA sequence repeated up to 5 minutes after injection of 7 mL Gd-BOPTA (MultiHance, Bracco, Italy) and 20 mL saline flush at a flow rate of 4 mL/s. Apparent diffusion coefficient (ADC) and time-signal intensity curve (TSIC) were obtained for both normal liver and each FNH by two reviewers in conference; maximum enhancement (ME) percentage, time to peak enhancement (TTP), and maximal slope (MS) were also calculated. Results: On DWI mean ADC value was 1.624×10(-3) mm(2)/s for normal liver and 1.629×10(-3) mm(2)/s for FNH. ADC value for each FNH and the normal liver was not statistically different (P=.936). On PWI, TSIC-Type 1 (quick and marked enhancement and quick decay followed by slowly decaying) was observed in all 52 FNHs, and TSIC-Type 2 (fast enhancement followed by slowly decaying plateau) in all normal livers. The mean ME, TTP and MS values were significantly different for FNH and normal liver (P=.005). Conclusion: FNHs of the liver showed typical diffusion and perfusion MRI characteristics in all cases. On the ADC map, we could get similar value between the FNHs and the background parenchyma. On the perfusion imaging, FNHs showed a different pattern distinguished from the background liver.
Poster: "ECR 2015 / C-1894 / Preoperative lymph node staging in patients with primary prosta... more Poster: "ECR 2015 / C-1894 / Preoperative lymph node staging in patients with primary prostate cancer: usefulness of diffusion-weighted MR imaging at 3T-device" by: "S. Ortori, P. Boraschi, V. Vallini, F. Manassero, M. Gabelloni, C. Selli, C. Bartolozzi; Pisa/IT"
Poster: "ECR 2013 / C-0799 / Evaluation of pelvic lymph nodes in patients with prostate canc... more Poster: "ECR 2013 / C-0799 / Evaluation of pelvic lymph nodes in patients with prostate cancer: usefulness of 3T Diffusion Weighted MR Imaging (DW-MRI)" by: "V. Vallini1, S. Ortori2, P. Boraschi2, V. Zampa2, F. Manassero2, C. Selli2, C. Bartolozzi2; 1Bellinzona/CH, 2Pisa/IT"
PURPOSE Our study was aimed to assess the diagnostic value of MR cholangiopancreatography (MRCP) ... more PURPOSE Our study was aimed to assess the diagnostic value of MR cholangiopancreatography (MRCP) and MR imaging at 3 T device when evaluating biliary adverse events after liver transplantation. MATERIALS AND METHODS A series of 384 MR examinations in 232 liver transplant subjects with suspected biliary complications (impaired liver function tests and/or biliary abnormalities on ultrasound) were performed at 3 T device (GE-DISCOVERY MR750; GE Healthcare). After the acquisition of axial 3D dual-echo T1-weighted images and T2-weighted sequences (propeller and SS-FSE), MRCP was performed through coronal thin-slab 3D-FRFSE and coronal oblique thick-slab SSFSE T2w sequences. DW-MRI of the liver was performed using an axial spin-echo echo-planar sequence with multiple b values (150, 500, 1000, 1500 s/mm2) in all diffusion directions. Contrast-enhanced MRCP was performed in 25/232 patients. All MR images were blindly evaluated by two experienced abdominal radiologists in consensus to determine the presence of biliary complications, whose final diagnosis was based on direct cholangiography, surgery and integrating clinical follow-up with ultrasound and/or MRI findings. RESULTS In 113 patients no biliary abnormality was observed. The remaining 119 subjects were affected by one or more of the following complications: non-anastomotic strictures including typical ischemic-type biliary lesions (n = 67), anastomotic strictures (n = 34), ampullary dysfunction (n = 4), anastomotic leakage (n = 4), stones, sludge and casts (n = 65), vanishing bile duct (n = 1). The sensitivity, specificity, PPV, NPV and diagnostic accuracy of the reviewers for the detection of all types of biliary complications were 99%, 96%, 95%, 99% and 97%, respectively. CONCLUSION MR cholangiopancreatography and MR imaging at 3 T device are extremely reliable for detecting biliary complications after liver transplantation.
Poster: "ECR 2010 / C-0024 / Ischemic-type biliary lesions following liver transplantation: ... more Poster: "ECR 2010 / C-0024 / Ischemic-type biliary lesions following liver transplantation: Evaluation with Gd-EOB-DTPA-enhanced MR cholangiography" by: "P. Boraschi, F. Donati, R. Gigoni, S. Salemi, F. Filipponi, C. Bartolozzi, F. Falaschi; Pisa/IT"
ABSTRACT Purpose: To present diffusion and perfusion magnetic resonance imaging (MRI) characteris... more ABSTRACT Purpose: To present diffusion and perfusion magnetic resonance imaging (MRI) characteristics of focal nodular hyperplasia (FNH) of the liver. Materials and methods: Thirty-five patients with 52 FNHs (21 were pathologically-confirmed) underwent MRI at 1.5-T device. MR diffusion [diffusion-weighted imaging (DWI)] was performed using a free-breathing single-shot, spin-echo, echo-planar sequence with b gradient factor value of 500 s/mm². MR perfusion [perfusion-weighted imaging (PWI)] consisted of a 3D free-breathing LAVA sequence repeated up to 5 minutes after injection of 7 mL Gd-BOPTA (MultiHance, Bracco, Italy) and 20 mL saline flush at a flow rate of 4 mL/s. Apparent diffusion coefficient (ADC) and time-signal intensity curve (TSIC) were obtained for both normal liver and each FNH by two reviewers in conference; maximum enhancement (ME) percentage, time to peak enhancement (TTP), and maximal slope (MS) were also calculated. Results: On DWI mean ADC value was 1.624×10(-3) mm(2)/s for normal liver and 1.629×10(-3) mm(2)/s for FNH. ADC value for each FNH and the normal liver was not statistically different (P=.936). On PWI, TSIC-Type 1 (quick and marked enhancement and quick decay followed by slowly decaying) was observed in all 52 FNHs, and TSIC-Type 2 (fast enhancement followed by slowly decaying plateau) in all normal livers. The mean ME, TTP and MS values were significantly different for FNH and normal liver (P=.005). Conclusion: FNHs of the liver showed typical diffusion and perfusion MRI characteristics in all cases. On the ADC map, we could get similar value between the FNHs and the background parenchyma. On the perfusion imaging, FNHs showed a different pattern distinguished from the background liver.
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Papers by Piero Boraschi