Papers by Fiorenzo Albani
Springer eBooks, 2004
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Bollettino - Lega Italiana contro l'Epilessia, Jul 1, 2003
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Cephalalgia, Dec 1, 1987
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The Lancet, Mar 1, 2007
... References. 1 Dauvilliers Y, Arnulf I, Mignot E. Narcolepsy with cataplexy. Lancet 2007; 369:... more ... References. 1 Dauvilliers Y, Arnulf I, Mignot E. Narcolepsy with cataplexy. Lancet 2007; 369: 499-511. Summary | Full Text | PDF(359KB) | CrossRef | PubMed. 2 Vignatelli L, D'Alessandro R, Candelise L. Antidepressant drugs for narcolepsy. Cochrane Library 2006; 4: 1-11. ...
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Journal of Chromatography B: Biomedical Sciences and Applications, Oct 1, 2001
ABSTRACT
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Neurophysiologie Clinique-clinical Neurophysiology, Dec 1, 1988
ABSTRACT
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European Journal of Clinical Pharmacology, Apr 1, 1991
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... Pharmacokinetics of metoclopramide after single oral dose administration in cirrhosis. Auteur... more ... Pharmacokinetics of metoclopramide after single oral dose administration in cirrhosis. Auteur(s) / Author(s). BERNARDI M. ; TAME MR ; ALBANI F. ; DE PALMA R. ; SCRIVANO P. ; TREVISANI F. ; GASBARRANI G. ; Affiliation(s) du ou des auteurs / Author(s) Affiliation(s). Univ. ...
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PubMed, Dec 1, 1981
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Epilepsy Research, Mar 1, 1991
Serial plasma samples collected after an acute administration of valproic acid, (VPA, 15 mg/kg as... more Serial plasma samples collected after an acute administration of valproic acid, (VPA, 15 mg/kg as oral solution) in epileptic patients were selected for this study. The plasma samples were selected from three different groups of patients; patients on phenobarbital and phenytoin with clinical VPA intolerance (group A); patients on phenobarbital and phenytoin without clinical VPA toxicity (group B); and patients without phenobarbital and phenytoin and without clinical VPA toxicity (group C). Plasma samples from 6 patients per group were analyzed for carnitines and ammonia. Ammonia levels during acute study increased significantly (P less than 0.05) in patients who experienced VPA intolerance, while no changes were found in the other patients. After acute VPA administration, total carnitine was unchanged but free carnitine was decreased (P less than 0.05) and carnitine esters were increased (P less than 0.05) in all groups of patients studied. No difference in carnitine profiles was seen between patients with or without evidence of VPA administration has an important effect on carnitine metabolism. However, unlike the acute effect on ammonia metabolism, this acute effect does not seem to be correlated with any associated antiepileptic therapy, nor does it predict clinical VPA intolerance.
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Clinical Pharmacokinectics, 1996
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PubMed, May 1, 1992
Recent development of analytical techniques for therapeutic drug monitoring of antiepileptic drug... more Recent development of analytical techniques for therapeutic drug monitoring of antiepileptic drugs are reviewed. The most commonly used procedures are high performance liquid chromatography (HPLC) and immunochemical techniques. Innovations in HPLC include commercialization of instrumentations for automatic extraction and injection of biological samples and development of restricted access media columns for direct injection of plasma without prior extraction. For immunochemical techniques, principles of "classical" major procedures are described together with the new immunoenzymatic and immunochromatographic methods in solid phase, specifically developed with the aim of making drug monitoring possible outside the traditional laboratory.
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Clinical Chemistry, Jun 1, 1982
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Journal of Chromatography B: Biomedical Sciences and Applications, 1986
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Epilepsia, Oct 1, 2013
SummaryPurposeTo present new information on the semiology and short‐term evolution of seizures as... more SummaryPurposeTo present new information on the semiology and short‐term evolution of seizures associated with primary brain tumors (PBTs) in a prospective study.MethodsThis study is a section of the PERNO study – Project of Emilia Romagna Region on Neuro‐Oncology, the main aim of which is to collect prospectively all cases of PBTs occurring in the Emilia‐Romagna region, northeast Italy (3,983,346 population) from January 2009 to December 2011, to allow epidemiologic, clinical, and biomolecular studies.The epilepsy section of the PERNO study included all the patients who experienced seizures, either as first symptom of the tumor or appearing during the course of the disease. Each patient was interviewed by the referring neurologist with a specific interest in epilepsy. The patients who entered the study were followed up with visits on a quarterly basis.Key FindingsWe collected 100 cases with full clinical, neuroradiologic, and pathologic data. The majority (79%) had high grade PBTs (glioblastoma in 50 cases), whereas the remaining patients had low‐grade gliomas, mostly localized in the frontal (60%), temporal (38%), and parietal (28%) lobes. Seizures were the first symptom of the tumor in 72 cases. Overall, the initial seizures were tonic–clonic (48%) (without clear initial focal signs in more than half of the patients), focal motor (26%), complex partial (10%), and somatosensitive (8%). The majority of cases (60%) had isolated seizures or a low seizure frequency at the onset of the disease, whereas a high seizure frequency or status epilepticus was observed in 18% and 12% of cases, respectively. Ninety‐two patients underwent surgical removal of the tumor, which was either radical (38%) or partial (53%). Seven patients underwent only cerebral biopsy. In the 72 patients in whom seizures were the first symptom, the mean time to the surgical treatment was 174 days, with a significant difference between high grade (95 days) and low grade (481 days) gliomas.At the time of our first observation, the majority of patients (69%) had already undergone surgical removal, with a mean follow‐up of 3 months after the procedure. Overall, 39 patients (56%) were seizure free after tumor removal. The good outcome did not depend on presurgical seizure frequency or tumor type, although there was a trend for better results with low‐grade PBTs.SignificanceThese data provide evidence that seizures are strictly linked to the tumoral lesion: They are the initial symptom of the tumor, reflect the tumor location and type, are usually resistant to antiepileptic treatment, and may disappear after the treatment of the lesion.
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Neurological Sciences, Oct 1, 2003
We examined the potential sex-related differences in levodopa pharmacokinetics and their relation... more We examined the potential sex-related differences in levodopa pharmacokinetics and their relation with the presence of dyskinesias in a group of 115 patients (67 men, 49 women) with Parkinson's disease. The patients were given a standard oral dose of levodopa plus benserazide (100/25 mg). The area under the levodopa plasma concentration time curve, corrected for the levodopa test dose (in mg/kg body weight), (AUC(w)) was significantly higher in women than in men, with a reduced oral clearance. No difference in the proportion of men and women experiencing dyskinesias was observed.
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Clinical Chemistry, Jun 1, 1983
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Papers by Fiorenzo Albani