Nikolay Dimitrov
Trakia UniversityLocation - Stara Zagora, BulgariaDepartment - Department of AnatomyPosition - Associate Professor
Phone: 0886334559
Address: Department of Anatomy
Faculty of Medicine
Trakia University
11 Armejska Str.
6000 Stara Zagora, Bulgaria
e-mail: nikolaydd@abv.bg
Phone : +359 42 664 413
Mobile: +359 886 33 45 59
Phone: 0886334559
Address: Department of Anatomy
Faculty of Medicine
Trakia University
11 Armejska Str.
6000 Stara Zagora, Bulgaria
e-mail: nikolaydd@abv.bg
Phone : +359 42 664 413
Mobile: +359 886 33 45 59
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of the Traditional Chinese Medicine (TCM). To
better understand the therapeutic effectiveness
of acupuncture, questions about the role of
mast cells (MCs) in acupuncture effect need to
be addressed. The MCs are associated mainly
with their involvement in innate immunity and
the mechanisms of defense against parasite
infections, immunomodulation of the immune
system and tissue repair. Manystudies have
beendevotedto the role ofMCs in acupuncture
and acupuncture points. Some results
revealed that the numbers of the MCs were
significantly larger along the meridian lines
in comparison with their control areas. Other
investigations reportedthatthere were no
significantdifferencesin the distribution ofMCs
betweenacupoint and non-acupoint areas.MCs
are a subject for research regarding changes in
tissue after acupuncture.Acupunctureis known
to cause alterations ofMCs in theacupuncture
pointsafteracupuncture. It leads to
tissuedislocationandmast cell degranulation.
Some researchers found evidence for the
existence of neuromastocytic junction and
its possible involvement in the effects of
acupuncture. Since MCs are important subject
for research inexperimental acupuncture,
the possible role of MCsdegranulation and
neuromastocytic junction should be considered
when discussing acupuncture effects.
Key words: acupoint, acupuncture, mast
cells