Papers by Mohammed Al-Biltagi
Pediatric Cardiology, Oct 7, 2014
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Journal of Allergy, Nov 23, 2012
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BENTHAM SCIENCE PUBLISHERS eBooks, Nov 3, 2015
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BENTHAM SCIENCE PUBLISHERS eBooks, Nov 3, 2015
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Pediatric Pulmonology, Nov 11, 2020
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BENTHAM SCIENCE PUBLISHERS eBooks, Nov 3, 2015
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BENTHAM SCIENCE PUBLISHERS eBooks, Nov 3, 2015
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Prensa médica argentina, 2014
ABSTRACT Asthma is a multifactorial disease. The increasing incidence of asthma in the last 6 dec... more ABSTRACT Asthma is a multifactorial disease. The increasing incidence of asthma in the last 6 decades may be related to the changes in population dietary habits with eating fewer fruits and vegetables and more processed foods. Diet plays an important role in the pathogenesis of asthma. Poor nutrition could also increase the likelihood of having asthma symptoms. Inadequate maternal nutrition during pregnancy could adversely impact childhood respiratory health, particularly during critical periods of embryonic and fetal growth and could increase the risks of asthma, chronic obstructive airway disease, and impaired lung functions. There are some controversies about the protective effect of breastfeeding on asthma. The effect of breastfeeding on asthma is influenced by different factors including duration of breastfeeding, the age of the child; hereditary factors as presence or absence of maternal asthma and atopy in the child, and environmental factors as exposure to tobacco smocking. With the new advancement of infant formula, as in partially or extensively hydrolyzed cow’s milk formula, the incidence of wheezing was significantly decreased than in infants fed with regular cow’s milk. The effect of bottle feeding is not only related to the milk but it could be also related to the plastic products used in the feeding bottles. Early or delayed weaning may be associated with increased risk of asthma and should not be started before 17 wk or delayed beyond 26 wk of age. Food allergy not only increases the incidence of childhood asthma, but also increases risk of asthma mortality and morbidity. However, the relationship between diet and asthma remains uncertain and needs further investigational studies.
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Cureus, Mar 9, 2023
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Down syndrome (DS) is the most frequent chromosomal disorders in the world. It occurs in all coun... more Down syndrome (DS) is the most frequent chromosomal disorders in the world. It occurs in all countries, all races, and both sexes. There are many factors affecting the occurrence of DS as it is multi-factorial and includes both genetic and environmental factors. These factors include the maternal age distribution in the population, efficiency and completeness of ascertainment, the degree of accuracy of diagnosis, the degree of acceptance of selective prenatal termination of affected pregnancies in the community, as well as different unrecognized genetic and environmental factors. Incidence of DS is found to be high in the developing countries, prob ably related to the higher morbidity due to the comorbidities associated with DS. Improving survival of infants with DS due to the improved provided health care affects the prevalence rather than the incidence of DS. The global predictable incidence of DS accord ing to World Health Organization is expected to be between 1-10/ 1000 live births all over the world. This article will discuss the difference in prevalence among different populations and countries and the potential risk factors affecting occurrence of DS in the community.
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World Journal of Clinical Pediatrics, May 9, 2021
Medical comorbidities are more common in children with autism spectrum disorders (ASD) than in th... more Medical comorbidities are more common in children with autism spectrum disorders (ASD) than in the general population. Some genetic disorders are more common in children with ASD such as Fragile X syndrome, Down syndrome, Duchenne muscular dystrophy, neurofibromatosis type I, and tuberous sclerosis complex. Children with autism are also more prone to a variety of neurological disorders, including epilepsy, macrocephaly, hydrocephalus, cerebral palsy, migraine/headaches, and congenital abnormalities of the nervous system. Besides, sleep disorders are a significant problem in individuals with autism, occurring in about 80% of them. Gastrointestinal (GI) disorders are significantly more common in children with ASD; they occur in 46% to 84% of them. The most common GI problems observed in children with ASD are chronic constipation, chronic diarrhoea, gastroesophageal reflux and/or disease, nausea and/or vomiting, flatulence, chronic bloating, abdominal discomfort, ulcers, colitis, inflammatory bowel disease, food intolerance, and/or failure to thrive. Several categories of inborn-errors of metabolism have been observed in some patients with autism including mitochondrial disorders, disorders of creatine metabolism, selected amino acid disorders, disorders of folate or B12 metabolism, and selected lysosomal storage disorders. A significant proportion of children with ASD have evidence of persistent neuroinflammation, altered inflammatory responses, and immune abnormalities. Anti-brain antibodies may play an important pathoplastic mechanism in autism. Allergic disorders are significantly more common in individuals with ASD from all age groups. They influence the development and severity of symptoms. They could cause problematic behaviours in at least a significant subset of affected children. Therefore, it is important to consider the child with autism as a whole and not overlook possible symptoms as part of autism. The physician should rule out the presence of a medical condition before moving on to other interventions or therapies. Children who enjoy good health have a better chance of learning. This can apply to all children including those with autism.
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Journal of Asthma and Allergy, 2023
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Arab Gulf Journal of Scientific Research, Jun 1, 2022
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World Journal of Clinical Cases, Aug 6, 2023
In recent years, because of the growing desire to improve the noninvasiveness and safety of tumor... more In recent years, because of the growing desire to improve the noninvasiveness and safety of tumor treatments, sonodynamic therapy has gradually become a popular research topic. However, due to the complexity of the therapeutic process, the relevant mechanisms have not yet been fully elucidated. One of the widely accepted possibilities involves the effect of reactive oxygen species. In this review, the mechanism of reactive oxygen species production by sonodynamic therapy (SDT) and ways to enhance the sonodynamic production of reactive oxygen species are reviewed. Then, the clinical application and limitations of SDT are discussed. In conclusion, current research on sonodynamic therapy should focus on the development of sonosensitizers that efficiently produce active oxygen, exhibit biological safety, and promote the clinical transformation of sonodynamic therapy.
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InTech eBooks, Jul 13, 2011
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World Journal of Clinical Pediatrics, Nov 9, 2022
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World Journal of Diabetes, May 15, 2023
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World Journal of Clinical Pediatrics, 2013
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World journal of methodology, Jul 20, 2022
Coronavirus disease 2019 (COVID-19) is a real challenge for humanity with high morbidity and mort... more Coronavirus disease 2019 (COVID-19) is a real challenge for humanity with high morbidity and mortality. Despite being primarily a respiratory illness, COVID-19 can affect nearly every human body tissue, causing many diseases. After viral infection, the immune system can recognize the viral antigens presented by the immune cells. This immune response is usually controlled and terminated once the infection is aborted. Nevertheless, in some patients, the immune reaction becomes out of control with the development of autoimmune diseases. Several human tissue antigens showed a strong response with antibodies directed against many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins, such as SARS-CoV-2 S, N, and autoimmune target proteins. The immunogenic effects of SARS-CoV-2 are due to the sizeable viral RNA molecules with interrupted transcription increasing the pool of epitopes with increased chances of molecular mimicry and interaction with the host immune system, the overlap between some viral and human peptides, the viral induced-tissue damage, and the robust and complex binding between sACE-2 and SARS-CoV-2 S protein. Consequently, COVID-19 and its vaccine may trigger the development of many autoimmune diseases in a predisposed patient. This review discusses the mutual relation between COVID-19 and autoimmune diseases, their interactive effects on each other, the role of the COVID-19 vaccine in triggering autoimmune diseases, the factors affecting the severity of COVID-19 in patients suffering from autoimmune diseases, and the different ways to minimize the risk of COVID-19 in patients with autoimmune diseases.
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World Journal of Clinical Pediatrics, Nov 9, 2022
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Papers by Mohammed Al-Biltagi