Karnitin O-oktanoiltransferaza
(преусмерено са Karnitin O-octanoyltransferaza)
| Karnitin O-oktanoiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.137 | ||||||||
| CAS broj | 39369-19-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Karnitin O-oktanoiltransferaza (EC 2.3.1.137, srednjelančana/dugolančana karnitin aciltransferaza, karnitin srednjelančana aciltransferaza, lako rastvorna mitohondrijska karnitinska palmitoiltransferaza) je enzim sa sistematskim imenom oktanoil-KoA:L-karnitin O-oktanoiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- oktanoil-KoA + L-karnitin KoA + L-oktanoilkarnitin
Ovaj enzim deluje na opseg acil-KoA molekula, sa optimalnom aktivnošću na C6 ili C8 acil grupama, cf. EC 2.3.1.7 (karnitin O-acetiltransferaza) i EC 2.3.1.21 (karnitin O-palmitoiltransferaza).
Reference
[уреди | уреди извор]- ^ Farrell, S.O., Fiol, C.J., Reddy, J.K. and Bieber, L.L. (1984). „Properties of purified carnitine acyltransferases of mouse liver peroxisomes”. J. Biol. Chem. 259: 13089—13095. PMID 6436243.
- ^ Healy, M.J., Kerner, J. and Bieber, L.L. (1988). „Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?”. Biochem. J. 249: 231—237. PMID 3342008.
- ^ Miyazawa, S., Ozasa, H., Osumi, T. and Hashimoto, T. (1983). „Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver”. J. Biochem. (Tokyo). 94: 529—542. PMID 6630173.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- Carnitine+O-octanoyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
