Papers by nelly abdelsalam
Dental Science Updates, 2021
ABSTRACTAim: To evaluate the effect of intra-canal cryotherapy on interleukin-1βand interleukin-1... more ABSTRACTAim: To evaluate the effect of intra-canal cryotherapy on interleukin-1βand interleukin-10 expression in teeth with symptomatic apical periodontitis.Methodology: Forty-eight single rooted teeth in patients with symptomatic apical periodontitiswere randomly divided into 4 groups according to the irrigation protocol.Group I (control); 5% sodium hypochlorite at room temperature. Group II; 5% coldsodium hypochlorite (2-5°C). Group III; final rinse with 20 mL of 5% cold sodiumhypochlorite (2-5°C) for 5 minutes. Group IV; final rinse with 20 mL of cold saline (2-5°C) for 5 minutes. Paper point passing 2 mm beyond the apex was used to collect periapicalfluid before, immediately after mechanical instrumentation and after one week tocharacterize the mRNA expression of IL-1β and Il-10 using real-time polymerase chainreaction (PCR). Statistical analysis was performed using one-way ANOVA to comparebetween all groups. Results: Our results revealed statistically significant (at P≤ 0.05)do...
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Aim: To evaluate the effect of intra-canal cryotherapy on interleukin-1β and interleukin-10 expre... more Aim: To evaluate the effect of intra-canal cryotherapy on interleukin-1β and interleukin-10 expression in teeth with symptomatic apical periodontitis. Methodology: Forty-eight single rooted teeth in patients with symptomatic apical periodontitis were randomly divided into 4 groups according to the irrigation protocol. Group I (control); 5% sodium hypochlorite at room temperature. Group II; 5% cold sodium hypochlorite (2-5°C). Group III; final rinse with 20 mL of 5% cold sodium hypochlorite (2-5°C) for 5 minutes. Group IV; final rinse with 20 mL of cold saline (25°C) for 5 minutes. Paper point passing 2 mm beyond the apex was used to collect periapical fluid before, immediately after mechanical instrumentation and after one week to characterize the mRNA expression of IL-1β and Il-10 using real-time polymerase chain reaction (PCR). Statistical analysis was performed using one-way ANOVA to compare between all groups. Results: Our results revealed statistically significant (at P≤ 0.05) ...
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Introduction: This study aimed to assess the radiographic and histopathologic outcomes of immatur... more Introduction: This study aimed to assess the radiographic and histopathologic outcomes of immature dog teeth with apical periodontitis after revascularization using propolis. Materials and Methods: Periapical pathosis was induced in 48 double-rooted premolars in six dogs aged 6–9 months. The root canals were irrigated with 10 mL of 2.25% NaOCl per tooth. The teeth were divided into two groups (24 teeth each) according to the disinfection of root canals as follows: Group I (propolis group): disinfected with propolis paste and Group II (control group): without disinfectant. After 3 weeks, bleeding was induced to fill the canal spaces, the pulp chamber of the teeth was plugged with mineral trioxide aggregate, and the access cavities were sealed with glass ionomer cement. Samples were classified into three subgroups depending on the evaluation period as follows: subgroup i: 2 weeks, subgroup ii: 4 weeks, and subgroup iii: 8 weeks. Increase in the root length and root thickness and decea...
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ABSTRACTIntroduction: intracanal medicaments have an important role in disinfecting ofthe pulp sp... more ABSTRACTIntroduction: intracanal medicaments have an important role in disinfecting ofthe pulp space and in endodontic regenerative procedures. These medications comein close contact with the periradicular tissue, thus their degradation products must bebiocompatible with the periapical tissue. Otherwise, these medicaments will resultin intense inflammatory reaction. Aim of the study: The purpose of this in vitrostudy was to evaluate and compare the cytotoxicity of three intracanal medications;Neem oil, double antibiotic paste (DAP) and calcium hydroxide (Ca(OH)2).Materials and Methods: Immortalized human gingival fibroblast cells were retrievedfrom the cell bank and then cultured. Three different intracanal medications (Neemoil, DAP, Ca(OH)2) were added to the cultured cells. Cell viability was evaluatedusing 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) andApoptosis/necrosis assays. Statistical analysis was performed using One-way ANOVAand post-hoc Tukey t...
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Introduction: Cryotherapy is a new form of treatment, in which the body is exposed to cold temper... more Introduction: Cryotherapy is a new form of treatment, in which the body is exposed to cold temperatures. Hence, this study was aimed to evaluate the effect of intracanal cryotherapy on postendodontic pain and interleukin-6 (IL-6) expression in teeth with symptomatic apical periodontitis. Materials and Methods: Forty-eight single-rooted teeth in patients with symptomatic apical periodontitis were randomly divided into four groups based on the irrigation protocol. Group I (control): 5% sodium hypochlorite (NaOCl) at room temperature (RT) was used during instrumentation and final rinse. Group II: 5% cold NaOCl (2°C–5°C) was used during the root canal procedure. Group III: 5% NaOCl at RT during instrumentation, while the final rinse was 20 mL of 5% cold NaOCl (2°C–5°C). Group IV: 5% NaOCl at RT during instrumentation followed by 20 mL of cold saline (2°C–5°C). Postoperative pain score was recorded using a modified visual analog scale at 12, 24, 48, and 72 h and after 1 week. Paper point...
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Journal of Endodontics
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Journal of Endodontics
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Papers by nelly abdelsalam