Effects of major and minor surgery on plasma glutamine and cytokine levels

M Parry-Billings, RJ Baigrie, PM Lamont… - Archives of …, 1992 - jamanetwork.com
• The plasma levels of glutamine and cytokines have been measured frequently in patients
before, during, and after elective abdominal aortic aneurysm surgery (" major surgery") or
inguinal hernia repair (" minor surgery"). The plasma glutamine level declined rapidly
following major surgery and remained markedly below preoperative levels until at least 7
days after surgery. This response of the plasma glutamine level was significantly correlated
with the production of interleukin 6 but not with that of interleukin 1, tumor necrosis factor, or …