[PDF][PDF] Characterization of inflammatory responses to eccentric exercise in humans

J Peake, KK Nosaka, K Suzuki - 2005 - ro.ecu.edu.au
Eccentric exercise commonly results in muscle damage. The primary sequence of events
leading to exercise-induced muscle damage is believed to involve initial mechanical
disruption of sarcomeres, followed by impaired excitation-contraction coupling and calcium
signaling, and finally, activation of calcium–sensitive degradation pathways. Muscle damage
is characterized by ultrastructural changes to muscle architecture, increased muscle proteins
and enzymes in the bloodstream, loss of muscular strength and range of motion and muscle …